Rhincodon typus (whale shark): 109915588
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Entry
109915588 CDS
T06055
Symbol
tyk2
Name
(RefSeq) non-receptor tyrosine-protein kinase TYK2
KO
K11219
non-receptor tyrosine-protein kinase TYK2 [EC:
2.7.10.2
]
Organism
rtp
Rhincodon typus (whale shark)
Pathway
rtp04217
Necroptosis
rtp04620
Toll-like receptor signaling pathway
rtp04621
NOD-like receptor signaling pathway
rtp05168
Herpes simplex virus 1 infection
Brite
KEGG Orthology (KO) [BR:
rtp00001
]
09140 Cellular Processes
09143 Cell growth and death
04217 Necroptosis
109915588 (tyk2)
09150 Organismal Systems
09151 Immune system
04620 Toll-like receptor signaling pathway
109915588 (tyk2)
04621 NOD-like receptor signaling pathway
109915588 (tyk2)
09160 Human Diseases
09172 Infectious disease: viral
05168 Herpes simplex virus 1 infection
109915588 (tyk2)
09180 Brite Hierarchies
09181 Protein families: metabolism
01001 Protein kinases [BR:
rtp01001
]
109915588 (tyk2)
Enzymes [BR:
rtp01000
]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.10 Protein-tyrosine kinases
2.7.10.2 non-specific protein-tyrosine kinase
109915588 (tyk2)
Protein kinases [BR:
rtp01001
]
Non-receptor tyrosine kinases
JAK family [OT]
109915588 (tyk2)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
PK_Tyr_Ser-Thr
Pkinase
FERM_F2
Jak1_Phl
FERM_F1
SH2_1
SH2
ABC1
APH
FERM_C_FAK1
Motif
Other DBs
NCBI-GeneID:
109915588
NCBI-ProteinID:
XP_048474057
LinkDB
All DBs
Position
38:complement(2120759..2212908)
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AA seq
1184 aa
AA seq
DB search
MALCPCTVTNSDTKLDGCHSSAPGLRVHLYWSSEGPQDLVFTEGEMVAEDICVLAAQKCS
ISPLCHNLYALCDLKENLWFPPNHIFKIDKDLCLTLHYRMRFYFKNWHGMSEKEPRVYRW
TPKRNDHEKFDQGSPLFDHMSLNYIFSQGKHDFVNGIAPLKEPQNEQELHVFQNESLGMA
VLHLSYIAVLSGRSLSEVAKEISFKGCIPKTFRAKIERCNALTKIRLKRGFRKFVRSFHL
PVVGSGKVIQHDIIFKYLSTLENLCTNFGGEVFRVSYLEVLPESSRTPYINNRNYLQTTE
DIICPTLPTQEYEVLVTGTEGIQWRILKKEPAPLKRTGWKSKPADSGSCKSTEIVEFTEK
PWSHFCDFKEITHIVISDCRVSVHRQDNKCLDLVLPSHKQALSFSALIDGYSRLTTDSHH
YLCHEVASPRVVLSITSGIHGPMQPHYVTTKLRREENKEGLYVLRWSALDFNKIIMTVVS
KEKPEFELLKGSGSFQDMKQFQIERKTPDAYVLQGWERSFPSVKELLESLKGCMLKSGNE
SYMVKKCCPPVPHEFSNLLITKNVKDSDVRPLTAQLNLSQLSFHQIRKEEIIQEHHLGRG
TRMNIYAGRFCEGEVEEEEEMDSPCGTSHSEARDIRVVLKVLDPSHRDIALAFFELASLM
SQISHAHLAFVHGVCVRGSENILVEEYVEFGPLDVLLRKERGKLNPEWSLTVIQQLASAL
SYLEDKNMVHGNICCKNVLVARKGLEEGSTPFIKVSDPGISFTVLTQEERVERIPWIAPE
CVQNVNKLSLGADKWSFGTTVLEICCNGEVPLKERTLSEKERFYEMKGKLPEPSCKELAD
LNSQCHSYEANQRPSFRTILRELTMLQQQNPDISCENSVPTVSDPTVFQKRYLKKVRDLG
EGHFGKVGLYIYDPFNDGTGEVVAVKSLKSECGEELHTSWTREIEILKTLYHDNIVKYKG
SSSEQGGQIVQLIMEYLPLGSLRDYLPKHAVGLGQLLLFAKQICQGMSYLQSQRYVHRDL
AARNVLVENENVVKIGDFGLAKAIPEHQDYYRVKDDGDSPVFWYAVDCLKEGKFNFASDV
WSFGVTLYELLTYCETRQSPPAKFIEMIGVTHGQMTVVRLIDLLERGQRLPCPKSCPLEV
YQLMNKCWESDPARRPPFQELIPVFQKLYERYKRIETSNILQKL
NT seq
3555 nt
NT seq
+upstream
nt +downstream
nt
atggcgctgtgcccctgcaccgtgacgaactctgacaccaagctggatggatgccactct
tcagcgccaggcttgagggtgcacctgtactggtcaagcgaaggcccacaggaccttgtt
tttaccgagggggagatggttgcagaagacatatgtgttctggctgcacagaaatgctcc
atttccccgctgtgccacaacttgtatgcactttgtgacttaaaagaaaatctttggttt
cctccgaatcatatcttcaagattgacaaggacctgtgtttgactctgcactatcgtatg
aggttttattttaagaactggcatggtatgtctgaaaaggagcctagggtataccgatgg
acaccgaagaggaatgaccatgagaaattcgaccaaggcagccctctgtttgaccacatg
tcgctcaactacatcttctcacagggtaaacacgattttgttaacggcatcgctcctctc
aaagaaccgcagaatgagcaggaattacacgtcttccaaaacgagagcctgggaatggcc
gtgctgcatctttcatacattgcagtcctgagtggacgctcacttagcgaagtggccaag
gaaataagttttaaggggtgcatcccaaagacattccgtgctaaaatagagaggtgtaat
gccctgaccaagatccggctgaaacgtggcttccgaaagtttgtaaggagcttccacctg
cctgtggttggttcggggaaggtgatccagcatgacattatattcaaatacctgtctacc
ttggagaacctttgcaccaactttggaggcgaggtctttcgtgtttcatatctggaagtg
cttccagaaagtagtaggaccccctacataaacaatcggaattacctgcagaccacagag
gatatcatctgccccacactacctacccaggaatatgaagtgctggtgactgggacagag
ggaattcagtggagaatacttaagaaggagcctgcacccctcaaaaggacaggctggaag
agcaaaccagcagacagtggcagctgcaaatccactgaaatagttgagttcactgagaag
ccatggtcgcacttttgtgatttcaaggagattacacacatcgtcatctctgactgcagg
gtcagtgttcacagacaggataacaaatgtctggaccttgtactgccctcacacaaacaa
gcactgtccttttcagcgctgatagatggctactctcgcctgaccactgactctcaccac
tatctgtgtcatgaggttgcttctccgcgggttgtgctgagcatcaccagtggcattcat
ggaccaatgcaaccgcactatgtcacaactaagctccgacgagaggagaacaaggaagga
ctctatgtgctgcgatggagtgctttagacttcaataagattatcatgacggttgtcagt
aaggaaaagcctgagtttgaattattgaaaggttctgggagttttcaagacatgaagcag
tttcagattgagaggaagaccccagacgcgtatgtgctgcagggctgggagcggtcattt
cccagtgtgaaagagctcctcgagagtcttaagggctgcatgctgaaatcggggaatgag
agctacatggtcaaaaagtgttgtccgcctgttccacatgaattctccaatttactcata
acgaagaatgtgaaagatagtgatgtgcgaccactcacagcgcagttaaatctgagccag
ctcagcttccatcaaataaggaaggaggaaatcattcaggagcatcatttgggccgtgga
acgaggatgaatatctacgctggtaggttttgcgagggtgaagttgaggaggaagaagag
atggactctccctgtggaacaagccacagtgaagcaagggatatccgtgtggtgttgaaa
gttcttgatcctagtcacagagacattgcattggcattcttcgagctggccagtctgatg
agtcaaatctctcatgctcacctcgccttcgtgcatggagtctgtgtgcggggctcagaa
aatatacttgtggaagaatatgtcgaatttggacctctggatgtcttgttgcgaaaggag
agaggaaagctgaacccagagtggagtctgactgtcattcagcaacttgctagtgcactg
agctacttggaggataaaaacatggtgcatgggaacatttgctgcaagaatgtgctcgta
gcgaggaaggggctggaagagggaagcacccctttcatcaaagtcagtgatcccggcatc
agtttcaccgtgcttactcaagaagaacgtgtggagcgaattccctggatcgctccagag
tgtgtccagaatgtgaacaagttaagtctgggtgctgacaaatggagctttgggacgacc
gtgctggaaatctgctgtaatggagaggtcccactgaaggagcgaacactgtctgagaaa
gagagattctacgagatgaaagggaaacttccagaaccttcctgtaaggagcttgctgac
ctgaatagccaatgtcacagctacgaagcaaaccaacggccatctttccggactattctg
cgggaactcacgatgctgcaacagcaaaatccggacatttcctgtgaaaattcagtgcct
accgtctctgaccccactgtcttccagaaacgctacctgaagaaggtccgagatcttgga
gagggtcacttcggcaaggtgggtctgtacatttatgacccatttaatgatggcacaggg
gaagttgtggcagtgaaatcgctgaagtcagagtgtggggaggagctccacacaagctgg
acacgggagatcgagattctgaaaacactgtaccacgacaacatcgtcaaatacaaaggc
agcagcagtgagcaaggaggtcagattgtacagctgattatggagtatctgccgctgggc
agtctgcgagattaccttccaaaacacgctgtcggacttgggcagcttctgctattcgca
aaacagatttgtcagggcatgtcgtacctccagtcgcagcggtatgtgcatcgtgatctg
gctgccaggaatgtcctggtggaaaatgagaatgttgtcaagattggggactttgggttg
gccaaagcgatccctgaacaccaggactattaccgagtgaaggatgatggagacagtcct
gtgttctggtatgctgttgactgtctcaaggaaggaaaattcaactttgcttctgatgtt
tggtcgtttggagtcacattatatgaacttttaacgtattgtgaaacccgccagagtcca
ccagctaaattcattgagatgattggagtgacgcatggacagatgacggtggtacgactg
attgatctgctggagaggggacagcgcttgccttgtccaaagtcttgccctttggaggtt
taccagctgatgaacaagtgttgggaatctgatccagctcgacgtcccccatttcaggag
ctgatcccagtctttcagaaactgtatgaaagatacaaaaggatagaaacttcaaacatt
ctccagaagttataa
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