Rathayibacter toxicus 70137: TI83_04985
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Entry
TI83_04985 CDS
T03670
Name
(GenBank) UDP-N-acetylmuramoylalanyl-D-glutamate--2,6-diaminopimelate ligase
KO
K01929
UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase [EC:
6.3.2.10
]
Organism
rtx
Rathayibacter toxicus 70137
Pathway
rtx00300
Lysine biosynthesis
rtx00550
Peptidoglycan biosynthesis
rtx01100
Metabolic pathways
rtx01502
Vancomycin resistance
Brite
KEGG Orthology (KO) [BR:
rtx00001
]
09100 Metabolism
09105 Amino acid metabolism
00300 Lysine biosynthesis
TI83_04985
09107 Glycan biosynthesis and metabolism
00550 Peptidoglycan biosynthesis
TI83_04985
09160 Human Diseases
09175 Drug resistance: antimicrobial
01502 Vancomycin resistance
TI83_04985
Enzymes [BR:
rtx01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.2 Acid-D-amino-acid ligases (peptide synthases)
6.3.2.10 UDP-N-acetylmuramoyl-tripeptide---D-alanyl-D-alanine ligase
TI83_04985
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Gene cluster
GFIT
Motif
Pfam:
Mur_ligase_M
Mur_ligase_C
Mur_ligase
WZC_N
CBM_20
Motif
Other DBs
NCBI-ProteinID:
AJM77474
UniProt:
A0A0C5BEL8
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All DBs
Position
1100776..1102200
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AA seq
474 aa
AA seq
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MIALTLAEIADSVSGRLHLSTSSANAATIVSGVTETDSREIAPNGIFVAKRGAQTDGHVF
ASAAVERGAALLIVERPLDLAVPQVIVDDSVTALGALATEVIRRARVLGGLSVVGITGSN
GKTTTKNLLRTILGRIGETVAPRGSYNNEVGAPITMLQVSESTRFLVAEMGASAVGEIRR
LVRMAKPDVGVVLAVGLAHAGSFGGVERTLEAKTEMVADLTADDIAVLNSDDARVVSMSE
RTPARILWFGRGESADVRALEVDSTVQGTRFTIEVTAGEGRQAARADLLLRVLGEHHVMN
ALAATAAALSLGVDLDEIVVALETVTLAEHGRMEVLGGAEVTIINDAYNASPDSTAAALR
TLAQIGPQYGRTVAVLGEMSELGEWADEEHERVGLLAVRLNIAQLVVVGAGARRIHVAAE
REGSWNGESVFAESADEAEKFLEGYLRAGDVALVKSSNSAGLRFLGDRLGERYR
NT seq
1425 nt
NT seq
+upstream
nt +downstream
nt
atgatcgccctcaccctcgccgagatcgccgattccgtgtcgggacggctgcacctgtcc
acgtcgtcagctaatgccgccaccatcgtgagcggagtcaccgaaaccgactcccgagaa
attgcgcccaacggcatttttgtggccaaacgcggcgcgcagaccgacggccatgtgttc
gcctcggcggccgtggagcgcggcgccgctctcctgattgtggagcgaccccttgatctt
gccgtgccgcaggtgattgttgatgactccgtcactgctctcggcgctttagcaaccgag
gtgatccggcgggcacgggtacttggcgggttgagcgttgtcgggatcaccgggtcgaac
ggtaagaccacgaccaagaacctcctccgcacaatcctcgggcgcatcggcgagacggtt
gctccgcggggctcgtataacaacgaggtcggcgcgccgatcaccatgctgcaggtgtcg
gaatcgactcgcttcctggtggcagagatgggagccagcgcggtcggcgagattcgtcgc
ctcgttcggatggctaagccagatgtgggagtggtgctcgcggtaggtctcgcacacgcc
ggctcgtttggtggcgttgaacgcaccctcgaggccaaaaccgaaatggtcgccgacctc
accgcggacgatattgcggtccttaactccgacgacgcccgagtggtctccatgtcggag
cgcaccccagcccgcatactctggtttgggcgtggcgaaagcgccgatgttcgcgcactc
gaggtggactccacggtgcagggcacccgtttcaccatcgaggtgacggcaggtgaaggt
cgtcaggctgcccgagcagacctgctgctgcgggtgctcggcgaacaccacgtcatgaat
gcgctggcagcgactgccgcggccctctccttgggcgtcgaccttgacgagatcgtggtc
gccctggagacggtcaccctcgccgagcacgggcggatggaggtgctcggaggtgcggag
gtcaccatcatcaacgacgcctacaacgcgagccccgactcgacggccgctgccctgcgt
accctcgcccaaatcggcccgcagtatggacgtacggttgcggtgctcggtgagatgagc
gagctgggagagtgggccgatgaggagcacgagcgcgtcggtctgctcgcggtgcgcctg
aacatcgcccagctcgtcgtcgttggtgctggcgcgcgtcgaattcacgtggcggcagag
cgtgaaggctcgtggaacggcgaatccgtctttgcggaatcggccgacgaggctgaaaaa
tttctcgaaggataccttcgtgccggtgacgtcgcactggtgaagtcgtcaaactcggcc
ggactgcgtttcctcggcgaccggcttggggagcggtaccggtga
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