Ruminococcus sp. SR1/5: CK1_24650
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Entry
CK1_24650 CDS
T02601
Name
(GenBank) UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase
KO
K01929
UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase [EC:
6.3.2.10
]
Organism
rum
Ruminococcus sp. SR1/5
Pathway
rum00300
Lysine biosynthesis
rum00550
Peptidoglycan biosynthesis
rum01100
Metabolic pathways
rum01502
Vancomycin resistance
Brite
KEGG Orthology (KO) [BR:
rum00001
]
09100 Metabolism
09105 Amino acid metabolism
00300 Lysine biosynthesis
CK1_24650
09107 Glycan biosynthesis and metabolism
00550 Peptidoglycan biosynthesis
CK1_24650
09160 Human Diseases
09175 Drug resistance: antimicrobial
01502 Vancomycin resistance
CK1_24650
Enzymes [BR:
rum01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.2 Acid-D-amino-acid ligases (peptide synthases)
6.3.2.10 UDP-N-acetylmuramoyl-tripeptide---D-alanyl-D-alanine ligase
CK1_24650
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Gene cluster
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Motif
Pfam:
Mur_ligase_M
Mur_ligase_C
Mur_ligase
Adeno_E3_CR1
Motif
Other DBs
NCBI-ProteinID:
CBL20416
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Position
complement(2147329..2148717)
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AA seq
462 aa
AA seq
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MKNLTLENITKVCNGIYHGPQEKLQEEVTAITTDSRKVEKGGLFVPVVGERVDAHRFIPQ
VMEAGALATLSERTLEGADHPYIQVGSSLQAVKDIAEFYLEQLDIPVVGITGSVGKTSTK
EVIASVLKEKYRTLKTQGNFNNELGLPLTVFRLRDEDEIAVLEMGISDFGEMTRLAKIAK
PDTCVITNIGTCHLENLGDRDGVLKAKTEIFQYVKRNIVLNGDDDKLSTVKEYNSMQPVF
FGNGENASVTCENVESRGLKGMSCDICLKGKMAENGEFQTFHVDIPMPGRHMVSNALAAA
AVGRLYGLNAEQIKNGIESLEPVSGRFNMIETDKFMIVDDCYNANPMSMKASLDVLQDGL
GRKVAILGDMGELGTDEAALHEGVGVHAGQCRIDACICVGPLAAHIAEKASQTNPDLTVI
REKDLESLLKNLNTYVKPGDTILVKASHFMKFENVVKALQEM
NT seq
1389 nt
NT seq
+upstream
nt +downstream
nt
atgaaaaatcttacattggaaaatatcacaaaagtctgcaatggtatttaccacggcccg
caggaaaaacttcaggaggaagtgactgcgatcacaacggacagccgtaaggtggaaaaa
ggaggtctttttgtaccggtagtaggagagcgtgtggatgctcaccgttttatcccgcag
gtaatggaagcaggtgcactcgcgaccttatccgagagaactcttgaaggggcggatcat
ccgtatatccaggtaggctcctcccttcaggcagtaaaagacattgcggagttttatctg
gagcagcttgatattccggttgtgggaatcacaggaagcgttggaaagaccagcacaaaa
gaggtgatcgcctctgtgctgaaggaaaaataccgtacactgaaaacccaggggaatttc
aacaatgagctgggacttccactgacagtattccgccttcgtgatgaagatgagatcgca
gttctggaaatgggaatcagtgatttcggtgagatgacccgtcttgcaaagatcgcaaaa
ccggacacctgcgtgatcacaaacatcggaacctgccatctggaaaaccttggggacaga
gacggcgtcctgaaggcaaaaacagagatttttcagtatgtgaagagaaatatcgtactt
aacggtgatgatgataagctctccacagtaaaggaatacaacagcatgcagccggtattt
ttcggaaacggagaaaatgcttctgttacctgtgaaaatgtggaaagccgtggcctgaag
ggaatgagctgtgacatctgtctgaagggaaaaatggcagagaacggagagttccagaca
tttcatgtagatattccaatgccgggacgtcatatggtatccaatgcactggcagcagca
gctgtgggcagactttacggactgaatgcagagcagatcaaaaatggcatcgaaagcctg
gaaccggtcagcggaagattcaatatgatcgagaccgataaattcatgatcgtagatgac
tgctacaacgcaaatcccatgtccatgaaggcgtccctggatgttcttcaggacggactt
ggaagaaaggttgccatccttggcgatatgggtgagcttggaacggatgaagctgcactt
catgaaggtgtaggcgttcatgcaggtcagtgcaggatcgatgcatgcatctgcgtagga
ccacttgcagcccatatcgcggaaaaagcatctcagaccaatccggacttgacagtcatc
cgggaaaaagatctggaaagccttcttaagaacctgaacacatatgtgaaacctggagat
accatcctcgtaaaggcttctcacttcatgaaatttgaaaatgtagtcaaagcactgcag
gaaatgtaa
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