Runella sp. SP2: DTQ70_19365
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Entry
DTQ70_19365 CDS
T05690
Name
(GenBank) UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase
KO
K01929
UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase [EC:
6.3.2.10
]
Organism
rup
Runella sp. SP2
Pathway
rup00300
Lysine biosynthesis
rup00550
Peptidoglycan biosynthesis
rup01100
Metabolic pathways
rup01502
Vancomycin resistance
Brite
KEGG Orthology (KO) [BR:
rup00001
]
09100 Metabolism
09105 Amino acid metabolism
00300 Lysine biosynthesis
DTQ70_19365
09107 Glycan biosynthesis and metabolism
00550 Peptidoglycan biosynthesis
DTQ70_19365
09160 Human Diseases
09175 Drug resistance: antimicrobial
01502 Vancomycin resistance
DTQ70_19365
Enzymes [BR:
rup01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.2 Acid-D-amino-acid ligases (peptide synthases)
6.3.2.10 UDP-N-acetylmuramoyl-tripeptide---D-alanyl-D-alanine ligase
DTQ70_19365
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Gene cluster
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Motif
Pfam:
Mur_ligase_M
Mur_ligase_C
Mur_ligase
DUF4350
FGGY_C
23ISL
Motif
Other DBs
NCBI-ProteinID:
AYQ34181
UniProt:
A0A3G3GSH4
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All DBs
Position
4833201..4834484
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AA seq
427 aa
AA seq
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MTISQLYDCFLACNGVSTDTRQIVEGCLFVALRGDKFDGNVYAKDALEKGAKYAIVDNSE
YAVDNRFLLVENSLEALQQLANHHRRQLNIPVVGLTGSNGKTTTKELIAAVLSKKFRTYA
TKGNLNNHIGVPLTLLAIDKSYEMAVVEMGANHQKEIALLSSIAEPTHGMITNIGKAHLE
GFGGIEGVRKGKGELFDWLSTSGGTVFVNGANATLQEMANERNFSEKVLYLADATAPQLL
EDTPLVIYQDAHQQTVHTHLTGRYNFENIAAALAIGAYFGVSDQDANAAVAEYNPTNNRS
QIIQKGSNTVIMDAYNANPSSMAAAIENFGKLKAERKMVILGDMLELGDESPTEHLALGK
LVAAQKFDVVILAGKLMKDALSALPKAYYFPDKFSLHNWVIDHPQQNTHVLIKGSRGMGL
ETVVPYL
NT seq
1284 nt
NT seq
+upstream
nt +downstream
nt
atgacgatttctcaattatacgattgctttttggcctgtaatggcgtttcaactgatacc
cgacaaattgttgaaggctgtttgtttgtagccctgcggggagataagtttgatggaaat
gtttatgccaaagatgcgttagaaaaaggagcaaaatacgccattgtggataactctgaa
tacgctgtggataaccgtttcctgttggtggaaaacagtttagaagcgcttcaacaattg
gccaaccaccaccgtcgtcaactcaacatcccagtagtaggcttgacaggttccaatgga
aaaaccactacaaaagagctgattgcggccgttttaagtaaaaaatttcgcacttacgct
accaaaggcaatcttaataaccacatcggtgtgccgctcacgctattggccatcgacaaa
agttacgaaatggccgtcgtagaaatgggtgccaaccaccaaaaagaaattgcccttctc
agcagcatcgccgagcctacccacggcatgattaccaacattggcaaagcccatttggaa
ggttttggaggaattgaaggagtccgcaaaggcaaaggagaattatttgattggctttcg
acttcgggcggtacggtgtttgtcaacggcgccaatgcgaccctccaagaaatggccaac
gagcgcaattttagtgaaaaggtactttacctagccgatgccactgccccgcaactgtta
gaagatactcctttggtgatttaccaagatgcccaccaacaaaccgttcatacgcatctg
acgggccggtacaattttgaaaatatcgccgcagctttggcgattggcgcttattttggc
gtttcggatcaagatgccaacgccgccgtcgcagagtacaatccgacgaataatcgctct
caaatcattcaaaaaggaagcaataccgtaattatggacgcttacaacgccaacccctct
tctatggcagccgctattgaaaactttgggaagttgaaagccgagcgtaaaatggtaatt
ttgggagatatgctcgaactaggcgacgaatcgcccacggaacacttagcactgggaaaa
ttggtagcggcgcaaaaatttgacgttgtcattttggcggggaagctcatgaaagatgcc
ttgtctgctttgccaaaagcctattatttccccgataaattctcattacacaactgggtt
attgatcatcctcaacaaaacacccatgtgcttatcaaaggctcaagaggaatgggatta
gagaccgttgttccgtatttgtag
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