Ruminococcus bicirculans (ex Wegman et al. 2014): RBI_I00189
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Entry
RBI_I00189 CDS
T03158
Symbol
hemD
Name
(GenBank) Uroporphyrinogen-III C-methyltransferase/Uroporphyrinogen-III synthase
KO
K13542
uroporphyrinogen III methyltransferase / synthase [EC:
2.1.1.107
4.2.1.75
]
Organism
rus
Ruminococcus bicirculans (ex Wegman et al. 2014)
Pathway
rus00860
Porphyrin metabolism
rus01100
Metabolic pathways
rus01110
Biosynthesis of secondary metabolites
rus01120
Microbial metabolism in diverse environments
rus01240
Biosynthesis of cofactors
Brite
KEGG Orthology (KO) [BR:
rus00001
]
09100 Metabolism
09108 Metabolism of cofactors and vitamins
00860 Porphyrin metabolism
RBI_I00189 (hemD)
Enzymes [BR:
rus01000
]
2. Transferases
2.1 Transferring one-carbon groups
2.1.1 Methyltransferases
2.1.1.107 uroporphyrinogen-III C-methyltransferase
RBI_I00189 (hemD)
4. Lyases
4.2 Carbon-oxygen lyases
4.2.1 Hydro-lyases
4.2.1.75 uroporphyrinogen-III synthase
RBI_I00189 (hemD)
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Gene cluster
GFIT
Motif
Pfam:
TP_methylase
HEM4
Motif
Other DBs
NCBI-ProteinID:
CCO03922
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Position
I:complement(223113..224573)
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AA seq
486 aa
AA seq
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MSGRVIIAGAGCGDYDLITMRGYEALKSCDVVIYDSLIDSRLLDFCKDGAEKICVGKRAG
RHSSTQEEINTLLVEKAAEGGVVLRLKGGDPFVFGRGGEEITALKAAGIPHSLIPGVTSS
VAVPELAGIPVSHRGLSRSFHVITGHTANDLLPEHFESYAKCGGTLIFLMGLRNLPEIAG
RLIENGMGENTPAAVISKGATPEQRAVKGCLDDIAEKVKREDLPAPAVIIVGETAGLDLS
PTYLPPLYGVSVAVTATKGLSRRLIKSLNALGAYAHRCGGFELRELNDEVTEKAFSRLSE
GFYSHVALTSPNGAEIFLKRLRESRIDIRKLSGVKIAVIGKGTGAKLEKAGLYADIMPEK
FNSVALGNMLSDTLTPEDRLLIVRSSEGSAELVKPLSEKWLNFDDVHIYEPVYSTGEKID
DDYAVFASAGGVRSFFSGGGSLSENTKCISIGEVTAAELKKYGINGPLLPTESTAEGIIQ
KILSDK
NT seq
1461 nt
NT seq
+upstream
nt +downstream
nt
atgagcggcagagttataatagcaggagcaggctgtggagattatgaccttatcacaatg
agaggttatgaggctctgaaaagctgtgacgtggtgatatatgacagccttatagacagc
cgtttgcttgacttttgcaaggacggtgcggagaaaatatgcgttggaaagcgtgcaggc
agacacagctccacgcaggaggagataaacacgcttcttgtggaaaaagccgcagagggc
ggtgttgttctcaggctaaaaggcggcgacccttttgtgttcggcagagggggcgaggag
ataactgcactcaaagccgcaggcataccacacagccttataccgggggtgacttcctcg
gtggcagtgcctgagcttgcaggtataccggtgagccacaggggactttcaagaagcttt
catgttataacaggtcacactgcgaacgacctgctccctgagcattttgaaagctatgca
aaatgcggtggaacgcttatttttcttatggggcttagaaatctccctgagatagcaggc
aggctcattgaaaacggtatgggcgaaaatactcctgcggcggtgatatcaaagggtgct
acccccgagcagagggctgtaaagggctgtcttgacgacattgctgaaaaggtgaagaga
gaggatctgcctgcgcctgcggtgataatagttggagaaaccgctgggcttgatctttcg
cctacctacctgcctccattgtatggagtttctgtggctgtcactgccacaaaggggctt
tcaaggcggcttataaagtcgctcaatgcccttggggcgtatgctcaccgctgtggcgga
tttgagcttagggagctgaacgatgaggtcacggaaaaagctttctcacggctttcagag
ggcttttacagccatgttgctcttacaagtccaaatggtgcggagatatttttgaaaagg
ctcagagaaagccgtattgacataagaaagctaagcggagtgaagatagctgtcataggc
aaaggcactggggcgaagcttgaaaaggctgggctttatgcagacataatgcctgaaaaa
ttcaacagcgtggctcttggaaatatgctctcggacactcttacccctgaggacaggctt
cttatagtacgctcctcggaggggtcagcggagcttgttaagccattgtctgaaaaatgg
ctgaactttgatgatgtgcatatttacgagcctgtttacagcacaggcgagaagatagat
gatgactacgctgtgtttgccagtgcaggcggagtgaggagctttttcagtggcggagga
agcttatcagagaatacaaagtgtatctccataggcgaagtgacggcggcagagctaaaa
aaatacggtataaatggtcctctgcttccaacggaaagcacggcagagggaataatacaa
aagatactttcagataagtga
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