Ruminococcus bicirculans (ex Wegman et al. 2014): RBI_I00562
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Entry
RBI_I00562 CDS
T03158
Symbol
leuB
Name
(GenBank) 3-isopropylmalate dehydrogenase
KO
K00052
3-isopropylmalate dehydrogenase [EC:
1.1.1.85
]
Organism
rus
Ruminococcus bicirculans (ex Wegman et al. 2014)
Pathway
rus00290
Valine, leucine and isoleucine biosynthesis
rus00660
C5-Branched dibasic acid metabolism
rus01100
Metabolic pathways
rus01110
Biosynthesis of secondary metabolites
rus01210
2-Oxocarboxylic acid metabolism
rus01230
Biosynthesis of amino acids
Module
rus_M00432
Leucine biosynthesis, 2-oxoisovalerate => 2-oxoisocaproate
Brite
KEGG Orthology (KO) [BR:
rus00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00660 C5-Branched dibasic acid metabolism
RBI_I00562 (leuB)
09105 Amino acid metabolism
00290 Valine, leucine and isoleucine biosynthesis
RBI_I00562 (leuB)
Enzymes [BR:
rus01000
]
1. Oxidoreductases
1.1 Acting on the CH-OH group of donors
1.1.1 With NAD+ or NADP+ as acceptor
1.1.1.85 3-isopropylmalate dehydrogenase
RBI_I00562 (leuB)
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Motif
Pfam:
Iso_dh
Motif
Other DBs
NCBI-ProteinID:
CCO04286
UniProt:
A0AAW6ECR2
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All DBs
Position
I:618226..619308
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AA seq
360 aa
AA seq
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MEKKITVIKGDGIGPEIVTEAQKVLDKVAEKFGHKFVYTDILMGGCSIDKYGVPLTDEAV
EIAKNSDAVLLGSIGGNTSTSPWYKLAPNLRPEAGLLKIRKELGLFANLRPANLYPELRE
ACPLKDDIIGDGFDMMIMRELTGGLYFGARKTENVDGVETAVDTLTYNENEIRRIAIRGF
DIAMKRRKKVTSVDKANVLDSSRLWRKVVNEVAKDYPEVELEHMLVDNCAMQLVRDPKQF
DVILTENMFGDILSDEAAMISGSLGMLASASLNDTKFGMYEPSHGSAPDIAGQDKANPIA
TILSASMLLRFSFDMDKEADAIDNAVKKVLEAGYRTGDIMSEDMKLVGCKEMGSLVADMI
NT seq
1083 nt
NT seq
+upstream
nt +downstream
nt
atggaaaagaaaataacagttataaagggcgacgggataggccctgaaatagtaacagaa
gcacagaaggtcctcgacaaggttgctgaaaagttcggtcataagtttgtttatactgat
atccttatgggcggctgttctatagataaatatggcgttccgcttacagacgaggctgtc
gagatagcaaagaactcagacgcagttctgcttggctctatcggcggaaatacttccact
tcaccatggtataagcttgctccgaacctcaggcctgaagccggactcctgaaaataaga
aaagagcttggtctgttcgctaacctgcgtcctgcaaatctttatcctgagcttagagaa
gcttgcccccttaaggacgatataatcggcgacggcttcgacatgatgataatgagagag
cttacaggcggtctgtattttggtgcgagaaagacagagaacgttgacggcgttgaaact
gccgttgatactcttacatataacgagaacgagataagaagaattgctatccgtggcttt
gacatcgccatgaagagaagaaagaaagttacaagcgttgataaggctaacgttcttgat
tcttcaagactttggagaaaggtagtaaacgaggtagctaaggattatcctgaggtcgag
cttgagcatatgctcgttgacaactgcgcaatgcagcttgtaagagatcctaagcagttt
gacgttatccttacagagaatatgttcggtgatatcctttctgacgaggctgcaatgata
tcaggctcacttggtatgctggcttccgcttcactgaacgacacaaagttcggtatgtat
gagcctagccacggctctgcacctgatatcgcaggacaggataaggctaatcctatcgct
actatactttcagcttcaatgctcctgagattttctttcgatatggataaggaagcagac
gctatcgacaatgctgtcaagaaagtccttgaagcaggctacagaacaggggatatcatg
tcagaggacatgaagctcgttggctgtaaggaaatgggcagtcttgttgcagatatgata
taa
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