Ruminococcus bicirculans (ex Wegman et al. 2014): RBI_I00950
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Entry
RBI_I00950 CDS
T03158
Symbol
purL
Name
(GenBank) Phosphoribosylformylglycinamidine synthase
KO
K01952
phosphoribosylformylglycinamidine synthase [EC:
6.3.5.3
]
Organism
rus
Ruminococcus bicirculans (ex Wegman et al. 2014)
Pathway
rus00230
Purine metabolism
rus01100
Metabolic pathways
rus01110
Biosynthesis of secondary metabolites
Module
rus_M00048
De novo purine biosynthesis, PRPP + glutamine => IMP
Brite
KEGG Orthology (KO) [BR:
rus00001
]
09100 Metabolism
09104 Nucleotide metabolism
00230 Purine metabolism
RBI_I00950 (purL)
Enzymes [BR:
rus01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.5 Carbon-nitrogen ligases with glutamine as amido-N-donor
6.3.5.3 phosphoribosylformylglycinamidine synthase
RBI_I00950 (purL)
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Gene cluster
GFIT
Motif
Pfam:
GATase_5
AIRS_C
FGAR-AT_linker
AIRS
GATase_3
Motif
Other DBs
NCBI-ProteinID:
CCO04665
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All DBs
Position
I:complement(1069026..1072739)
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AA seq
1237 aa
AA seq
DB search
MSVYRIYVEKKPEFAVEANSLIGGIKSALGLENLTGLRVINRYDAEGLSREDFDLAAPVV
FSEPAVDVTYDHLPAVKADEFVFAVEYLPGQFDQRADSCAQCISLLTGGKRPTIKSARIY
IVSGKLTEAELDQIKHYMINPVESREASLDCFDTLDIKYTIPTTVKTVEGFIYSTDDDLK
FMLTDLGLAMDFDDIKFCQDYFKNVEKRNPTITEIRMIDTYWSDHCRHTTFSTIVDNVSI
DSDYIAATFADYINTRKDLYAGRTDKPVTLMDLACIGAKQLKKAGLLKDLDESEEINACS
VKITVDVDGNPEDWLLMFKNETHNHPTEIEPFGGAATCLGGAIRDPLSGRSYVYQAMRVT
GAGNPLVPVEDTITGKLPQRKIVVGAANGYSSYGNQIGLATGHVHEIYHPGYVAKRMEIG
AVIGAAPAENVRRERPEPEDIVILLGGRTGRDGCGGATGSSKSHNLHSLENCGAEVQKGN
APEERKLQRLFRNPEVTSMIKRCNDFGAGGVSVAIGELADGLSINLDAVTKKYDGLDGTE
LAISESQERMAVVIAKSDLEKFMAEAAKENLEATMVARVTAEPRLKMNWCGNTIVDLTRE
FLNSNGAEKHTDISIPAPVFAAESNDADTADRWESMISNLNICSQKGLIERFDSTIGANT
VLMPFGGKYQNTPTQAMAAKLPVLHGNTKTTSIMGWGYDPYLSSVSPYHGAMSAVVESIA
KVIATGGIYEKCWLTFQEYFERTQNDPERWGKPMSALLGAYKAQIELGCGSIGGKDSMSG
TFEEIDVPPTLVSFAVSVTDADKVVSQEFKKAGSKVILIKPEYDDNKLVNFDSLKAVFKK
VEKLIAEGKVLSCWAVSYGGVSEAVAKMAFGNKIGFKFTDKLTAEELYRACYGAFVIELA
EGVDTDERVIGETTESYEIKSDNYTISLDKLQTLWEGKLEPVYPVHVKEPAEKPEKYSYK
ADKRVAPAIKVAKPKVLIPVFPGTNCEYDTARAFEKAGAEADIFVVRNLTEQAIKESVDA
MEKKIKESQIVMLPGGFSGGDEPDGSGKFIVSFLRNPRLTDAIHDLLKNRDGLMLGICNG
FQALIKLGLVPYGEIRDMRDDSPTLTFNTIARHQSKMVNTRIASNKSPWLAGCEVGDIHS
VAISHGEGRFVATAEEIAQLAANGQIATQYVDFDGEPTFDIHCNPNTSFQAIEGITSPDG
RVLGKMGHSERKGCCVSKNVPGEKDQKIFESGVAYFK
NT seq
3714 nt
NT seq
+upstream
nt +downstream
nt
atgtctgtttaccgtatttatgtagaaaaaaagcctgaatttgcagttgaagcaaattca
cttatcggcggaataaagtcagctctgggacttgaaaaccttacaggtctgagagttata
aaccgctatgacgcagagggtctttcaagagaggattttgaccttgcagcaccagtcgtt
ttctctgagcctgctgttgacgttacttacgatcacctgcctgctgtaaaagctgacgag
tttgtttttgcagttgagtatctgccaggtcagtttgatcagagagctgattcctgcgca
cagtgtatctcacttctcactggaggaaaaagacctactatcaagtcagcgagaatttat
atcgtttctggcaaactcacagaagcagagcttgaccagatcaagcactatatgataaac
cctgttgagtcaagagaagcttcccttgattgcttcgatacacttgatatcaagtatact
atccctaccacagttaagactgttgagggctttatctattcaacagacgatgacctgaaa
tttatgctcacagacttgggtcttgcaatggactttgacgatatcaagttctgtcaggat
tatttcaagaacgttgaaaagagaaatcctactatcactgagataagaatgatagataca
tactggtctgaccactgccgccatactacattctccactatcgtcgataacgtttctatc
gactcagactacatagctgctacctttgcagactatatcaacacaagaaaagacctttat
gcaggcagaactgacaagcctgttacacttatggatcttgcttgtatcggcgcaaaacag
cttaaaaaggctggtctgctcaaagaccttgacgagagtgaggagataaacgcttgctct
gttaagataacggttgacgttgacggcaatcctgaggactggctgctcatgttcaaaaac
gaaacacacaaccaccctacagagatcgagcctttcggcggtgcggcaacttgcctcggc
ggtgctatcagagaccctctgtcaggacgttcatatgtatatcaggcaatgagagtaaca
ggcgcaggcaatccgctggttcctgttgaggacactatcacaggtaagcttccacagaga
aagatagttgtaggtgcggcaaatggttattcttcatacggcaaccagataggtcttgct
accggtcacgttcacgagatatatcacccaggctatgttgcgaagagaatggagataggt
gctgtaatcggtgctgctcctgctgagaacgtaagacgtgaaagacctgagcctgaggat
atcgttatcctccttggcggaagaacaggacgtgacggctgcggcggagcaacaggttct
tcaaaatcacacaacctccactcacttgaaaactgcggagctgaggtacagaagggtaac
gcacctgaggaaagaaagcttcagcgtttgttcagaaatcctgaagttacttcaatgata
aagcgttgtaacgacttcggtgcaggcggagtttccgttgctatcggcgagcttgctgac
ggactttctatcaaccttgacgctgttacaaagaagtatgacggtcttgacggcactgag
cttgctatctctgagtcacaggagagaatggctgttgttatcgcaaagagcgaccttgaa
aagttcatggctgaggctgcaaaggaaaaccttgaagcaacaatggtggcaagagtaact
gctgagccaagacttaaaatgaactggtgcggcaacactatcgttgacctaacaagagag
tttcttaactcaaacggtgctgaaaagcacacagatatttccatccctgctcctgttttc
gcagcagagagcaacgatgctgacactgctgaccgctgggagtctatgatatcaaacctc
aacatatgctcacagaagggtcttattgagagatttgactcaacaatcggtgcaaacaca
gttcttatgccatttggcggtaaatatcagaacacacctacacaggcaatggctgcaaag
ctccctgttcttcacggcaatacaaagacaacgtccattatgggctggggctatgaccca
tatctctcatctgtaagcccataccacggcgcaatgagcgctgtagttgagtctatcgca
aaggtcatcgcaacaggcggtatatatgagaagtgctggctcacattccaggagtatttc
gagagaacacagaatgatcctgagcgttggggcaagcctatgtctgctctcctcggtgca
tacaaggcacagatagagctgggatgcggttctatcggcggtaaggactcaatgtcaggt
acattcgaggaaatagacgttccacctacacttgtttcattcgctgtatcagtaacagac
gcagacaaggtagtttcacaggaattcaagaaggccggctctaaggtaattcttatcaag
cctgagtatgatgacaacaagcttgtgaacttcgattcacttaaggcagtatttaaaaag
gtagaaaagcttatcgctgagggcaaggtgctttcatgctgggctgtatcctacggcggt
gtatccgaggctgttgcaaaaatggcatttggtaacaagataggctttaagttcacagac
aagctcacagcagaagaactttacagagcttgctatggcgcatttgttatcgagcttgct
gagggcgttgacactgacgagagagttatcggtgaaacaacagaaagctatgagataaag
tcagacaattacacaataagccttgacaagctccagacactttgggagggcaagcttgaa
cctgtatatcctgttcatgtgaaagagcctgctgaaaagcctgaaaagtacagctacaag
gcagacaagagagtcgcacctgctatcaaggtggcaaagccaaaggtgcttatccctgta
ttccctggcacaaactgcgaatacgatacagcaagagcctttgaaaaggcaggcgctgag
gctgacatcttcgttgtaagaaaccttacagaacaggctatcaaggagtctgttgacgca
atggagaagaagataaaagagtcacagatagtaatgctcccaggcggattcagcggtggc
gacgagcctgacggttcaggcaagttcatcgtatcattcctgagaaacccaaggcttaca
gacgctatccatgacctgctgaaaaatcgtgacggtcttatgcttggtatctgcaacggc
ttccaggcacttatcaagcttggtcttgtaccatatggtgagataagagatatgagagac
gactcccctacactgacattcaacaccattgcaagacaccagtctaaaatggtaaacaca
aggatcgcttccaacaagtcaccatggcttgcaggctgtgaggtaggcgatatccacagc
gtggctatctcacacggtgagggacgtttcgttgcaacagcagaggagatcgcacagctt
gctgcaaacggacagatcgctacacagtatgttgactttgacggagagcctacatttgac
attcattgcaaccctaacacatcattccaggctatcgagggtatcacctcacctgacgga
cgtgttcttggtaaaatgggtcactcagagcgtaagggctgctgcgtatcaaagaacgtt
cctggtgaaaaggatcagaagatatttgaaagcggcgtagcttacttcaagtaa
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