Staphylococcus aureus subsp. aureus COL (MRSA): SACOL2042
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Entry
SACOL2042 CDS
T00225
Symbol
ilvD
Name
(GenBank) dihydroxy-acid dehydratase
KO
K01687
dihydroxy-acid dehydratase [EC:
4.2.1.9
]
Organism
sac
Staphylococcus aureus subsp. aureus COL (MRSA)
Pathway
sac00290
Valine, leucine and isoleucine biosynthesis
sac00770
Pantothenate and CoA biosynthesis
sac01100
Metabolic pathways
sac01110
Biosynthesis of secondary metabolites
sac01210
2-Oxocarboxylic acid metabolism
sac01230
Biosynthesis of amino acids
Module
sac_M00019
Valine/isoleucine biosynthesis, pyruvate => valine / 2-oxobutanoate => isoleucine
sac_M00570
Isoleucine biosynthesis, threonine => 2-oxobutanoate => isoleucine
Brite
KEGG Orthology (KO) [BR:
sac00001
]
09100 Metabolism
09105 Amino acid metabolism
00290 Valine, leucine and isoleucine biosynthesis
SACOL2042 (ilvD)
09108 Metabolism of cofactors and vitamins
00770 Pantothenate and CoA biosynthesis
SACOL2042 (ilvD)
Enzymes [BR:
sac01000
]
4. Lyases
4.2 Carbon-oxygen lyases
4.2.1 Hydro-lyases
4.2.1.9 dihydroxy-acid dehydratase
SACOL2042 (ilvD)
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Gene cluster
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Motif
Pfam:
ILVD_EDD_N
ILV_EDD_C
adh_short_C2
Motif
Other DBs
NCBI-ProteinID:
AAW37005
UniProt:
Q5HEE8
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Position
2101069..2102757
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AA seq
562 aa
AA seq
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MRSDMIKKGDHQAPARSLLHATGALKSPTDMNKPFVAICNSYIDIVPGHVHLRELADIAK
EAIREAGAIPFEFNTIGVDDGIAMGHIGMRYSLPSREIIADAAETVINAHWFDGVFYIPN
CDKITPGMILAAMRTNVPAIFCSGGPMKAGLSAHGKALTLSSMFEAVGAFKEGSISKEEF
LDMEQNACPTCGSCAGMFTANSMNCLMEVLGLALPYNGTALAVSDQRREMIRQAAFKLVE
NIKNDLKPRDIVTREAIDDAFALDMAMGGSTNTVLHTLAIANEAGIDYDLERINAIAKRT
PYLSKIAPSSSYSMHDVHEAGGVPAIINELMKKDGTLHPDRITVTGKTLRENNEGKEIKN
FDVIHPLDAPYDAQGGLSILFGNIAPKGAVIKVGGVDPSIKTFTRKAICFNSHDEAVEAI
DNRTVRAGHVVVIRYEGPKGGPGMPEMLAPTSSIVGRGLGKDVALITDGRFSGATRGIAV
GHISPEAASGGPIALIEDGDEITIDLTNRTLNVNQPEDVLARRRESLTPFKAKVKTGYLA
RYTALVTSANTGGVMQVPENLI
NT seq
1689 nt
NT seq
+upstream
nt +downstream
nt
atgcgaagcgacatgatcaaaaaaggagatcaccaagcaccagcaagaagtcttttacat
gccacgggcgcgctaaaaagtccaactgatatgaacaaaccatttgtagctatttgtaac
tcttatattgatattgttcctggacatgttcacttgagagagcttgcagatatagctaaa
gaagcaattagagaagccggtgccattccatttgaattcaatacaattggtgttgatgat
ggaatagctatgggacatatcggaatgcgatattctctaccatcacgtgaaattattgca
gatgcagctgaaactgtaattaacgctcattggtttgacggcgtattttacattcctaat
tgtgacaagattacacccggtatgattttagcagccatgaggacaaacgtaccagctatc
ttttgctctggtggaccaatgaaagctggcttatctgcacatggaaaagcattaacactt
tcatcaatgtttgaagcagtcggcgcatttaaagaaggatcgatttctaaagaagaattt
ttagatatggaacaaaatgcctgccctacttgtggttcatgtgctgggatgtttactgca
aattcaatgaactgtttgatggaagttttaggtctagcattaccatacaacggtactgca
cttgcagtcagtgatcagcgacgagaaatgattcgccaagcagcttttaaattagttgaa
aatattaaaaatgatttaaaaccacgtgatatcgttactcgcgaagcaattgatgatgca
tttgcacttgatatggctatgggtggttcaacaaacacggtactgcatacgttagccatt
gccaatgaagctggtattgattatgacttagagcgcattaatgctattgccaaacgcacg
ccatatttatcaaaaatagcacctagttcatcgtattcaatgcatgatgtgcatgaagct
ggtggcgtcccagcaattattaatgaattgatgaagaaagatggcacgttacacccagat
agaatcacagttactggcaaaacgttacgtgaaaataacgaaggcaaagaaattaagaac
tttgatgtcattcaccctcttgatgcaccatatgatgcacaaggcggtttatctatctta
tttggtaatatcgcccctaaaggcgcagttattaaagttggcggcgttgatccatctatc
aaaacatttactaggaaagcaatttgtttcaattcgcatgatgaagctgttgaagcaata
gacaatcgtaccgttcgtgcaggccacgtcgttgtcattagatatgaaggacctaaaggt
ggaccaggtatgcctgaaatgttagcacctacttcctctattgttggtcgcggcttaggt
aaagatgttgcattaattactgatgggcgtttttccggtgccacaagaggtattgcagtt
ggtcatatttcccctgaagctgcatctggtggaccaattgccttaattgaagatggtgat
gagattactattgatttaacaaatcgtacattaaacgtaaaccagcctgaagatgttcta
gcgcgtcgccgagaatctttaacaccatttaaagcgaaagtaaaaacaggttatctagct
cgttatactgccctagtaactagcgcaaatacaggtggcgtcatgcaagtccctgagaat
ttaatttaa
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