Saccharopolyspora sp. ASAGF58: FDZ84_04295
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Entry
FDZ84_04295 CDS
T06538
Name
(GenBank) UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase
KO
K01929
UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase [EC:
6.3.2.10
]
Organism
sacg
Saccharopolyspora sp. ASAGF58
Pathway
sacg00300
Lysine biosynthesis
sacg00550
Peptidoglycan biosynthesis
sacg01100
Metabolic pathways
sacg01502
Vancomycin resistance
Brite
KEGG Orthology (KO) [BR:
sacg00001
]
09100 Metabolism
09105 Amino acid metabolism
00300 Lysine biosynthesis
FDZ84_04295
09107 Glycan biosynthesis and metabolism
00550 Peptidoglycan biosynthesis
FDZ84_04295
09160 Human Diseases
09175 Drug resistance: antimicrobial
01502 Vancomycin resistance
FDZ84_04295
Enzymes [BR:
sacg01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.2 Acid-D-amino-acid ligases (peptide synthases)
6.3.2.10 UDP-N-acetylmuramoyl-tripeptide---D-alanyl-D-alanine ligase
FDZ84_04295
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Motif
Pfam:
Mur_ligase_M
Mur_ligase_C
Mur_ligase
Motif
Other DBs
NCBI-ProteinID:
QIZ34097
UniProt:
A0A6H1R381
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All DBs
Position
complement(972969..974438)
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AA seq
489 aa
AA seq
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MIRLSLADIAEAVVGRLHRAESSEIVSAGVEFDSRKIEPGGLFVAVPGEQVDGHDFAAQA
VANGAVGVLAAREVDAPAVIVPPVSGDAAGALALAGDVDGSGAAVLAGLAKLARHVVDRL
PQLTVVGVTGSSGKTSTKDLIAQLLEPMGPTVAPPGSFNNELGHPWTVLRADEGTRHLVL
ELSARGVGHIANLCEVAPPRIGAVLNVGHAHLGEFGSQEAVAQAKGELVEALPADGVAVL
NADDPLVAAMADRTKARVVFVGESPGAQVRAADIEVDDLARPTFTLVTAQGEARVTLPLF
GEHHVGNALTAAAIALELGATVEQVAERLGSVRRVSARRMEVSETPGGVTVVDDAYNANP
ESVRAALKTLAAMTRGRPGRAWAVLGPMAELGELDVEAHDEIGRLAVRLNIDRLVVVGEQ
ARAMHQAASLEGSWGEESVLVPDIDAAVALLRAELRPGDVVLAKASNSAGLWRVAEALLA
EGDSGGRKP
NT seq
1470 nt
NT seq
+upstream
nt +downstream
nt
ttgatccggctcagcctcgccgacatcgcggaagcggtggtcggcaggcttcatcgtgcg
gaaagctcggagatcgtaagcgcgggtgtcgagttcgactcgcgcaagatcgaacccggc
gggctgttcgtggccgtgcccggggaacaggtcgacgggcatgacttcgcggcgcaggcc
gtcgcgaatggtgcggtgggcgttctcgccgcgcgggaggtcgacgccccggcagtgatc
gtgccgccggtgagcggcgacgcggcgggcgcgctggcgctggccggtgacgtggacggc
tccggcgccgcggtgctggccgggctggcgaagctggcccgccacgtggtcgaccggctg
ccgcagctcaccgtggtaggcgtgaccggctcgtcgggcaagacgtccacgaaggacctg
atcgcgcagctgctggaaccgatggggccgacggtcgcgccgcccggctcgttcaacaac
gagctcggccacccgtggaccgtgctgcgcgccgacgagggcacccggcacctggtgctg
gagctgtccgcgcgcggcgtcgggcacatcgcgaacctgtgcgaggtggctccgccgcgc
atcggcgcggtgctcaacgtcggccacgcgcacctcggcgagttcggctcgcaggaggcg
gtggcgcaggccaagggcgaactggtcgaggcgctgcccgccgacggcgtggcggtgctc
aacgccgacgacccgctggtcgcggcgatggccgaccggacgaaggcccgcgtggtcttc
gtcggggaaagccccggcgcgcaggtgcgcgcggcggacatcgaggtcgacgacctggcg
cgaccgacgttcacgctggtcaccgcgcagggcgaggcccgggtgacgctgccgcttttc
ggcgagcaccacgtgggcaacgcgctgaccgcggccgccatcgcgctggagctcggagcg
accgtcgagcaggtggccgagcggctcggctcggtgcgccgggtgtccgcgcggcgcatg
gaggtcagcgagacaccgggcggcgtcacggtcgtcgacgacgcctacaacgccaacccg
gaatcggtccgggcggcgctgaagacgctggccgcgatgacccgcgggcgcccgggccgg
gcgtgggcggtgctggggccgatggccgaactcggcgagttggatgtagaagcgcacgac
gagatcgggcggctggccgtccgcctgaacatcgaccggctggtggtggtcggcgaacag
gcccgggcgatgcaccaggcggcatcgctggaagggtcgtggggagaggagtcggttctg
gtgccggacatcgatgcggccgtcgcgctgctgcgcgccgagctgcgtcccggtgacgtg
gtgctcgccaaggcatcgaactccgccgggctgtggcgggtcgccgaagccctgctggcc
gagggagattcaggggggcgcaagccgtga
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