Saccharopolyspora sp. ASAGF58: FDZ84_05730
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Entry
FDZ84_05730 CDS
T06538
Symbol
leuC
Name
(GenBank) 3-isopropylmalate dehydratase large subunit
KO
K01703
3-isopropylmalate/(R)-2-methylmalate dehydratase large subunit [EC:
4.2.1.33
4.2.1.35
]
Organism
sacg
Saccharopolyspora sp. ASAGF58
Pathway
sacg00290
Valine, leucine and isoleucine biosynthesis
sacg00660
C5-Branched dibasic acid metabolism
sacg01100
Metabolic pathways
sacg01110
Biosynthesis of secondary metabolites
sacg01210
2-Oxocarboxylic acid metabolism
sacg01230
Biosynthesis of amino acids
Module
sacg_M00432
Leucine biosynthesis, 2-oxoisovalerate => 2-oxoisocaproate
Brite
KEGG Orthology (KO) [BR:
sacg00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00660 C5-Branched dibasic acid metabolism
FDZ84_05730 (leuC)
09105 Amino acid metabolism
00290 Valine, leucine and isoleucine biosynthesis
FDZ84_05730 (leuC)
Enzymes [BR:
sacg01000
]
4. Lyases
4.2 Carbon-oxygen lyases
4.2.1 Hydro-lyases
4.2.1.33 3-isopropylmalate dehydratase
FDZ84_05730 (leuC)
4.2.1.35 (R)-2-methylmalate dehydratase
FDZ84_05730 (leuC)
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GFIT
Motif
Pfam:
Aconitase
AcnX
Motif
Other DBs
NCBI-ProteinID:
QIZ34331
UniProt:
A0A6H1R1N0
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All DBs
Position
complement(1265801..1267204)
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AA seq
467 aa
AA seq
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MGKTLAEKVWEAHIVRRGEGHEPDLLYIDLHLVHEVTSPQAFEGLRLAGRPVRRPDLTLA
TEDHNVPTTGIDLPIADPVSRTQVDTLRKNCEEFGIRLHPMGDAEQGIVHVVGPQLGLTQ
PGTTVVCGDSHTSTHGAFGALAFGIGTSEVEHVLATQTLPLKPFKTMAINIEGTLRPGVT
SKDVILAVIAKIGTGGGQGYVLEYRGEAIRQLSMEARMTICNMSIEAGARAGMIAPDETT
FDYLEGRPHAPEGAEWGAAVEYWKTLRTDDDATFDAEVTLNADELTPFVTWGTNPGQGLP
LGEQVPDPAQIVDEGERFAAEKALAYMGLTPGTPLREVSVDTVFLGSCTNGRIEDLRAAA
EVLKGRKVAADVRMLVVPGSMKVRQQAESEGLHEVFTAAGAEWRSAGCSMCLGMNPDQLT
PGERSASTSNRNFEGRQGKGGRTHLVSPLVAAATAVRGTLSAPEDLD
NT seq
1404 nt
NT seq
+upstream
nt +downstream
nt
atgggaaaaacgctcgcggagaaggtttgggaagcgcacatcgtgcgccgtggtgaaggg
cacgagccagacctgctctacatcgatctccacctggtgcacgaggtcaccagtccgcag
gccttcgaagggcttcggttggcgggccggccggtgcgccgccccgatctgacgctggcc
accgaagaccacaacgtgcccaccaccgggatcgacctgccgatcgccgacccggtgtcc
cgcacgcaggtcgacaccttgcggaagaactgcgaggaattcggcatccgcctgcacccg
atgggcgacgccgagcagggcatcgtgcacgtcgtcgggccgcagctcggcctgacgcag
ccgggcaccaccgtggtctgcggcgacagccacacctcgacgcacggcgctttcggcgcg
ttggccttcggcatcggcacttccgaggtcgagcacgtgctggccacccagacgctgccg
ctgaagccgttcaagaccatggccatcaacatcgaaggcaccctgcgcccgggagtcacc
agcaaggacgtgatcctggccgttatcgcgaagatcggcaccggcggcggccagggctac
gtcctggagtaccgcggcgaagcgatccgccagctgtccatggaagcccgcatgacgatc
tgcaacatgtcgatcgaggcgggcgcgcgggccggcatgatcgcgcccgacgaaacgact
ttcgactacctcgaggggcgcccgcacgcccccgagggcgccgagtggggcgccgccgtc
gagtactggaagacgctgcgcaccgacgacgacgccacattcgacgcagaagttacgctg
aacgcggatgaactgaccccgttcgtcacctggggcaccaacccggggcagggcctgccg
ctgggcgagcaggtgccggacccggcgcagatcgtcgacgagggcgagcggttcgccgcc
gagaaggccttggcgtacatgggcttgacccccgggacgccgctgcgcgaggtgtccgtg
gacaccgtgttcctcggctcctgcaccaatggccggatcgaggacctgcgcgccgccgcc
gaggtcctcaagggccgcaaggtcgccgcggacgtgcggatgctcgtcgtgcccggctcg
atgaaggtccgccagcaggcggagtccgaagggctgcacgaggttttcaccgccgccggc
gcggaatggcgttcggccggttgttcgatgtgcctgggcatgaacccggaccagctcacg
ccgggcgagcgcagcgcgtcgacctccaaccgcaacttcgagggcaggcaaggcaagggc
ggccgcacccacctggtctccccgctggtcgccgcggccaccgccgtgcgcggaaccctg
tccgcccccgaagacctcgactga
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