Saccharopolyspora sp. ASAGF58: FDZ84_11590
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Entry
FDZ84_11590 CDS
T06538
Symbol
pdhA
Name
(GenBank) pyruvate dehydrogenase (acetyl-transferring) E1 component subunit alpha
KO
K00166
2-oxoisovalerate dehydrogenase E1 component subunit alpha [EC:
1.2.4.4
]
Organism
sacg
Saccharopolyspora sp. ASAGF58
Pathway
sacg00280
Valine, leucine and isoleucine degradation
sacg00640
Propanoate metabolism
sacg00785
Lipoic acid metabolism
sacg01100
Metabolic pathways
sacg01110
Biosynthesis of secondary metabolites
sacg01210
2-Oxocarboxylic acid metabolism
Module
sacg_M00036
Leucine degradation, leucine => acetoacetate + acetyl-CoA
Brite
KEGG Orthology (KO) [BR:
sacg00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00640 Propanoate metabolism
FDZ84_11590 (pdhA)
09105 Amino acid metabolism
00280 Valine, leucine and isoleucine degradation
FDZ84_11590 (pdhA)
09108 Metabolism of cofactors and vitamins
00785 Lipoic acid metabolism
FDZ84_11590 (pdhA)
Enzymes [BR:
sacg01000
]
1. Oxidoreductases
1.2 Acting on the aldehyde or oxo group of donors
1.2.4 With a disulfide as acceptor
1.2.4.4 3-methyl-2-oxobutanoate dehydrogenase (2-methylpropanoyl-transferring)
FDZ84_11590 (pdhA)
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Motif
Pfam:
E1_dh
TPP_enzyme_C
Motif
Other DBs
NCBI-ProteinID:
QIZ35230
UniProt:
A0A6H1R4Y8
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Position
complement(2452345..2453562)
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AA seq
405 aa
AA seq
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MSPEQWTRPEAEGADGPPAAIAAKPTREQVIAGLRATSEGGADLVQLLTPEGQRVTHPDF
DIDVSDAQLRDLYRDMVLVRRADREGNALQRQGQLGIWVPLLGQEAAQIGAGRAMQPQDM
AFPSYREHGVAWCRGIDPTELLGIFRGTDHGSWDPNSTRFHLYTIVIGNQCLNATGYAMG
QRFDGKVGDPDGEATMVFFGDGATSQGDVHEAMVWSAVYDAPVVFFCQNNQWAISEPIER
QTRVPLYRRASGYGFPGIRVDGNDVLASLAVTKWALDECRQGNGPVLIEAFTYRMDAHTT
SDDPTRYRLADEQEAWKLKDPIERLRVHLVREQIADQGFFDGVDAGADELAARLRDFCFN
MPEPPPERMFSEVYAEDTPQLAAQREDYLKYLAGFADDAMAGGVR
NT seq
1218 nt
NT seq
+upstream
nt +downstream
nt
atgtcccccgagcaatggacgcgacccgaagccgaaggcgccgacggcccccctgccgct
atcgcagcgaaacccacacgggagcaggtgatcgccggtttgcgcgccacgagcgaaggt
ggagctgacctggttcagctactcaccccggaaggccaacgggtaacacaccccgacttc
gacatcgacgtctccgacgcgcagctgcgcgacctgtaccgggacatggtgctggtccgc
cgcgccgaccgggagggcaacgccctgcagcggcagggccagctgggcatctgggtcccg
ctgctcggccaggaagccgcccagatcggcgccggccgggcgatgcagccgcaggacatg
gcgttccccagctaccgggagcacggcgtcgcctggtgccgcggcatcgacccgaccgag
ctgctgggcatcttccgcggtaccgaccacggcagctgggacccgaacagcacgcggttc
cacctctacacgatcgtcatcggcaaccagtgcctgaacgccaccggttatgcgatgggc
cagcgcttcgacggcaaggtcggcgacccggacggcgaggccaccatggtcttcttcggc
gacggcgccaccagccagggcgacgtgcacgaggccatggtgtggtcggcggtctacgac
gccccggtggtgttcttttgccagaacaaccagtgggcgatctccgagccgatcgagcgc
cagactcgcgtgccgctctaccgccgcgccagcgggtacggcttccccggcatccgggtg
gacggcaacgacgtgctggccagcctcgcggtcaccaagtgggcgctggacgagtgccgc
cagggcaacgggccggtgctgatcgaggcgttcacctaccggatggacgcgcacaccacc
tccgacgacccgacccgctaccggctggccgacgagcaggaggcctggaagctcaaggat
ccgatcgaacgactgcgggtgcacctggtccgcgagcagatcgccgaccagggcttcttc
gacggcgtcgacgccggagccgacgagctcgccgcccggctgcgcgacttctgcttcaac
atgcccgaaccaccaccggagcgaatgttctccgaggtttacgcggaggacaccccgcag
ctggccgcccagcgcgaggattacctcaagtacctggccggtttcgccgacgacgcgatg
gcaggaggtgtgcgctga
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