Streptomyces actuosus: DMT42_23900
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Entry
DMT42_23900 CDS
T08084
Symbol
purH
Name
(GenBank) bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/inosine monophosphate cyclohydrolase
KO
K00602
phosphoribosylaminoimidazolecarboxamide formyltransferase / IMP cyclohydrolase [EC:
2.1.2.3
3.5.4.10
]
Organism
sact
Streptomyces actuosus
Pathway
sact00230
Purine metabolism
sact00670
One carbon pool by folate
sact01100
Metabolic pathways
sact01110
Biosynthesis of secondary metabolites
Module
sact_M00048
De novo purine biosynthesis, PRPP + glutamine => IMP
Brite
KEGG Orthology (KO) [BR:
sact00001
]
09100 Metabolism
09104 Nucleotide metabolism
00230 Purine metabolism
DMT42_23900 (purH)
09108 Metabolism of cofactors and vitamins
00670 One carbon pool by folate
DMT42_23900 (purH)
09180 Brite Hierarchies
09183 Protein families: signaling and cellular processes
04147 Exosome [BR:
sact04147
]
DMT42_23900 (purH)
Enzymes [BR:
sact01000
]
2. Transferases
2.1 Transferring one-carbon groups
2.1.2 Hydroxymethyl-, formyl- and related transferases
2.1.2.3 phosphoribosylaminoimidazolecarboxamide formyltransferase
DMT42_23900 (purH)
3. Hydrolases
3.5 Acting on carbon-nitrogen bonds, other than peptide bonds
3.5.4 In cyclic amidines
3.5.4.10 IMP cyclohydrolase
DMT42_23900 (purH)
Exosome [BR:
sact04147
]
Exosomal proteins
Exosomal proteins of other body fluids (saliva and urine)
DMT42_23900 (purH)
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Paralog
Gene cluster
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Motif
Pfam:
AICARFT_IMPCHas
MGS
Motif
Other DBs
NCBI-ProteinID:
AWT45036
UniProt:
A0A2U9P5R1
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Position
5067627..5069189
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AA seq
520 aa
AA seq
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MTAESNKRPIRRALVSVYDKTGLEELARGLHEAGVELVSTGSTASRIAAAGVPVTKVEEL
TGFPECLDGRVKTLHPRVHAGILADLRLDSHREQLAELGVEPFDLVVVNLYPFRETVASG
ATPDECVEQIDIGGPSMVRAAAKNHPSVAVVTSPERYADVLAAVQDGGFDLAARKRLAAE
AFRHTAEYDIAVSSWFASSYAPADDSQFPEFIAATLERAHTLRYGENPHQPAALYVSGEG
GLAAAEQLHGKEMSYNNYTDTDAARRAAYDHAEPCVAIIKHANPCGIAIGADVAEAHRKA
HACDPVSAYGGVIAVNRPVSKEMAEQVAEIFTEVIVAPDYEEGALEALTKKKNIRVLRCP
GGPAHPVEVKPIDGGALLQVADRLQADGDDPANWTLASGEALGEDELQQLAFAWKACRAV
KSNAILLAKDGASVGVGMGQVNRVDSCKLAVERAGEERARGAYAASDAFFPFPDGPEILI
AAGVRAIVQPGGSIRDEQVVEAAKKAGVTMYFTGTRHFFH
NT seq
1563 nt
NT seq
+upstream
nt +downstream
nt
gtgaccgccgagagcaacaagcggccgattcgccgggcgctcgtcagcgtctacgacaag
accggcctggaggagctggcccgcgggctgcacgaggccggggtcgagctggtgtcgacc
gggtccaccgcctcccgtatcgccgccgccggcgtccccgtcaccaaggtcgaggagctg
accggcttccccgagtgcctggacggccgggtcaagaccctgcacccgcgcgtgcacgcc
ggcatcctcgccgacctgcgcctcgacagccaccgcgagcagctcgccgagctgggcgtg
gagccgttcgacctcgtcgtcgtcaacctctaccccttccgcgagaccgtcgcctccggc
gccacgccggacgagtgcgtcgagcagatcgacatcggcggcccctccatggtccgcgcc
gccgccaagaaccacccctcggtggccgtggtcaccagccccgagcggtacgccgacgtc
ctcgcggccgtccaggacggcggcttcgacctcgccgcccgcaagcgcctggccgcggag
gccttccggcacacggcggagtacgacatcgccgtctcctcctggttcgcctcctcctac
gcgccggccgacgactcccagttccctgagttcatcgccgccaccctggagcgcgcgcac
accctgcgctacggcgagaacccgcaccagccggccgcgctgtacgtctccggcgagggc
ggcctcgcggccgccgagcagttgcacggcaaggagatgtcgtacaacaactacacggac
acggacgccgcccgccgtgccgcgtacgaccacgccgagccctgcgtcgcgatcatcaag
cacgccaacccctgcggcatcgcgatcggcgcggacgtcgccgaggcgcaccgcaaggcg
cacgcctgcgacccggtctccgcgtacggcggtgtcatcgccgtgaaccggccggtcagc
aaggagatggccgagcaggtcgcggagatcttcaccgaggtcatcgtcgccccggactac
gaggagggggccctggaggccctcaccaagaagaagaacatccgggtgctgcgctgcccc
ggcggccccgcgcaccccgtcgaggtcaagccgatcgacggcggcgcgctgctccaggtc
gccgaccggctccaggccgacggcgacgacccggccaactggacgctggccagcggcgag
gcgctcggtgaggacgagctgcagcagctcgccttcgcctggaaggcgtgccgcgcggtg
aagtccaacgcgatcctgctcgccaaggacggcgcctcggtcggcgtcggcatgggccag
gtcaaccgcgtcgactcgtgcaagctcgccgtggagcgggcgggcgaggagcgggcccgc
ggcgcgtacgccgcctcggacgcgttcttcccgttccccgacggtcctgagatcctcatc
gccgccggggtgcgggccatcgtccagccgggcggctcgatccgcgacgagcaggtcgtg
gaggccgcgaagaaggcgggtgtcacgatgtacttcaccggcacccgccacttcttccac
tag
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