KEGG   Streptomyces actuosus: DMT42_27465
Entry
DMT42_27465       CDS       T08084                                 
Name
(GenBank) ketol-acid reductoisomerase
  KO
K00053  ketol-acid reductoisomerase [EC:1.1.1.86]
Organism
sact  Streptomyces actuosus
Pathway
sact00290  Valine, leucine and isoleucine biosynthesis
sact00770  Pantothenate and CoA biosynthesis
sact01100  Metabolic pathways
sact01110  Biosynthesis of secondary metabolites
sact01210  2-Oxocarboxylic acid metabolism
sact01230  Biosynthesis of amino acids
Module
sact_M00019  Valine/isoleucine biosynthesis, pyruvate => valine / 2-oxobutanoate => isoleucine
sact_M00570  Isoleucine biosynthesis, threonine => 2-oxobutanoate => isoleucine
Brite
KEGG Orthology (KO) [BR:sact00001]
 09100 Metabolism
  09105 Amino acid metabolism
   00290 Valine, leucine and isoleucine biosynthesis
    DMT42_27465
  09108 Metabolism of cofactors and vitamins
   00770 Pantothenate and CoA biosynthesis
    DMT42_27465
Enzymes [BR:sact01000]
 1. Oxidoreductases
  1.1  Acting on the CH-OH group of donors
   1.1.1  With NAD+ or NADP+ as acceptor
    1.1.1.86  ketol-acid reductoisomerase (NADP+)
     DMT42_27465
SSDB
Motif
Pfam: KARI_N KARI_C F420_oxidored NAD_binding_2 2-Hacid_dh_C AdoHcyase_NAD PDH_N NAD_Gly3P_dh_N Rossmann-like ApbA NAD_binding_7 CoA_binding GFO_IDH_MocA
Other DBs
NCBI-ProteinID: AWT45660
UniProt: A0A2U9P7D0
LinkDB
Position
5896962..5897960
AA seq 332 aa
MAELFYDADADLSIIQGRKVAVIGYGSQGHAHALSLRDSGVDVRVGLHEGSKSKAKAEEQ
GLRVVTPAEAAAEADVIMILVPDPIQAQVYEESIAPHLKDGDALFFGHGFNIRFGFIKPP
AGVDVCMVAPKGPGHLVRRQYEEGRGVPCIAAVEQDASGNAFALALSYAKGIGGTRAGVI
KTTFTEETETDLFGEQAVLCGGTAALVKAGFETLTEAGYQPEIAYFECLHELKLIVDLMY
EGGLEKMRWSISETAEWGDYVTGPRIITDATKAEMKKVLAEIQDGTFAQQWMDEYHGGLK
KYNEYKQQDSEHLLETTGKQLRKLMSWVDEEA
NT seq 999 nt   +upstreamnt  +downstreamnt
gtggccgagctgttctacgacgccgacgccgacctgtccatcatccagggccgcaaggtc
gcggtcatcggttacggcagccagggccacgcccacgcgctgtcgctccgtgactcgggt
gtcgacgtgcgtgtcggtctgcacgagggctccaagtccaaggccaaggccgaggagcag
ggcctgcgcgtggtgacgccggccgaggccgccgccgaggcggacgtcatcatgatcctg
gtgccggacccgatccaggcccaggtctacgaggagtccatcgccccgcacctgaaggac
ggcgacgcgctgttcttcggccacggcttcaacatccgcttcggcttcatcaagcccccg
gccggcgtggacgtctgcatggtcgccccgaagggcccgggccacctggtgcgccgtcag
tacgaggagggccgcggcgttccgtgcatcgccgccgtcgagcaggacgcctccggcaac
gccttcgcgctggccctgtcgtacgccaagggcatcggcggcacccgcgccggcgtcatc
aagacgaccttcaccgaggagaccgagaccgacctgttcggtgagcaggccgtgctgtgc
ggtggcaccgccgcgctggtgaaggcgggcttcgagacgctgaccgaggccggctaccag
ccggagatcgcctacttcgagtgcctgcacgagctgaagctgatcgtggacctcatgtac
gagggcggcctggagaagatgcgctggtcgatctccgagaccgccgagtggggcgactac
gtcaccggcccgcggatcatcaccgacgccaccaaggccgagatgaagaaggtcctcgcc
gagatccaggacggcaccttcgcccagcagtggatggacgagtaccacggcggcctgaag
aagtacaacgagtacaagcagcaggactccgagcacctgctggagaccaccggcaagcag
ctgcgcaagctgatgagctgggtcgacgaggaggcgtaa

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