Streptomyces actuosus: DMT42_33795
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Entry
DMT42_33795 CDS
T08084
Symbol
egtA
Name
(GenBank) ergothioneine biosynthesis glutamate--cysteine ligase EgtA
KO
K01919
glutamate--cysteine ligase [EC:
6.3.2.2
]
Organism
sact
Streptomyces actuosus
Pathway
sact00270
Cysteine and methionine metabolism
sact00480
Glutathione metabolism
sact01100
Metabolic pathways
sact01240
Biosynthesis of cofactors
Brite
KEGG Orthology (KO) [BR:
sact00001
]
09100 Metabolism
09105 Amino acid metabolism
00270 Cysteine and methionine metabolism
DMT42_33795 (egtA)
09106 Metabolism of other amino acids
00480 Glutathione metabolism
DMT42_33795 (egtA)
Enzymes [BR:
sact01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.2 Acid-D-amino-acid ligases (peptide synthases)
6.3.2.2 glutamate---cysteine ligase
DMT42_33795 (egtA)
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Motif
Pfam:
GCS2
Motif
Other DBs
NCBI-ProteinID:
AWT46770
UniProt:
A0A2U9PAI0
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Position
complement(7392116..7393435)
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AA seq
439 aa
AA seq
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MSDSVSGCTDIAAVTEPEVEALVKGICFKTGPPRTLGVEVEWLVHELHAPRLPVSPERLE
AAYAALRTVPLRSALTVEPGGQLELSSLPAASLTECIGTVSADLDAVRAVLRAQGLGLVG
LGHDPWHPPRRYLREPRYDAMEACLDRTGPAGRGMMCTSASVQVCLDAGYEEPGPLGHGR
RWWLAHTLGAVLVAAFANSPLALGRATGWRSTRQLLWAEIGPGRAGAPGPDGDPRAAWAR
HVLDSPVMCIRRDGGPWEVPEGLTFRQWIRSGAPRPPTRADLDYHITTLFPPVRPRGHLE
LRMIDAQPGDDGWIVPLAVTAALFDDAQAAETAYRTVKPLAERSGGLPAPHNPLWTAAAR
DALADPELHEAAVACFGTALEALPRLGAGPRVTGAVAAYLDRYVRKGRCPADDLLDRLDG
TAPAGPPPRTTAHGKDIRQ
NT seq
1320 nt
NT seq
+upstream
nt +downstream
nt
atgtccgactcggtaagtggctgtacggatatcgcggcagtcaccgaacccgaagtggaa
gccctggtcaagggcatctgcttcaagaccggaccgccccgcaccctcggggtggaagtg
gaatggctggtccacgagctgcacgcaccgcggctccccgtatcgcccgaacgtctcgaa
gcggcctacgccgccctgcgtaccgtgcccctgcggtcggcgctcaccgtcgaacccggc
ggtcagctggagctgagctcgctccccgccgcctcgctcaccgagtgcatcggtaccgtc
tccgccgacctggacgccgtccgcgccgtgctgcgcgcccagggcctgggcctggtgggc
ctcggccacgacccctggcacccgccccggcggtatctgcgcgagccgcgctacgacgcc
atggaggcctgcctcgaccgcaccggcccggccggccgcggcatgatgtgcacctcggcc
tcggtccaggtctgcctggacgccgggtacgaggagcccggcccgctcgggcacgggcgg
cgctggtggctcgcgcacaccctgggcgcggtcctcgtggccgccttcgccaactcgccg
ctggccctgggccgggcgaccggctggcgctccacccggcagctgctgtgggcggagatc
ggccccggccgggcgggcgccccgggcccggacggcgatccgcgcgcggcctgggcccgg
cacgtgctggacagcccggtgatgtgcatccgccgggacggcggcccgtgggaggtgccg
gaggggctcaccttccggcagtggatccgttcgggcgcgccccggccgcccacccgggcg
gacctggactaccacatcaccaccctgttcccgccggtccggccgcgcggccatctggag
ctgcggatgatcgacgcgcagcccggcgacgacggctggatcgtgccgctcgccgtcacg
gccgcgctcttcgacgacgcgcaggccgccgagaccgcctaccgcaccgtgaagccgctg
gccgagcggtccggggggctgcccgcgccgcacaacccgctgtggaccgccgcggcacgc
gacgcgctggccgaccccgagctgcacgaggccgccgtggcctgcttcggcacggccctg
gaggcgctgccgcggctcggcgccgggccgcgggtcaccggtgccgtcgcggcctacctg
gaccgctacgtccgcaaggggcgctgccccgccgacgatctgctcgaccgactggacggg
acggccccggccgggcccccgccccgcacgaccgcgcacgggaaggacatccgccagtga
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