Sporomusa acidovorans: SPACI_021150
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Entry
SPACI_021150 CDS
T10566
Symbol
murF
Name
(GenBank) UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase
KO
K01929
UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase [EC:
6.3.2.10
]
Organism
sacv Sporomusa acidovorans
Pathway
sacv00300
Lysine biosynthesis
sacv00550
Peptidoglycan biosynthesis
sacv01100
Metabolic pathways
sacv01502
Vancomycin resistance
Brite
KEGG Orthology (KO) [BR:
sacv00001
]
09100 Metabolism
09105 Amino acid metabolism
00300 Lysine biosynthesis
SPACI_021150 (murF)
09107 Glycan biosynthesis and metabolism
00550 Peptidoglycan biosynthesis
SPACI_021150 (murF)
09160 Human Diseases
09175 Drug resistance: antimicrobial
01502 Vancomycin resistance
SPACI_021150 (murF)
Enzymes [BR:
sacv01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.2 Acid-D-amino-acid ligases (peptide synthases)
6.3.2.10 UDP-N-acetylmuramoyl-tripeptide---D-alanyl-D-alanine ligase
SPACI_021150 (murF)
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Gene cluster
GFIT
Motif
Pfam:
Mur_ligase_M
Mur_ligase_C
Mur_ligase
Motif
Other DBs
NCBI-ProteinID:
XFO72069
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Position
2242939..2244321
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AA seq
460 aa
AA seq
DB search
MADFSVSEILKATGGHLLHAGDKKVFRGVSTDTRNIKSSNLFIALVGERFDGNDFVAQAA
AKGAAGLLVSRAVSVPAGVTVIQVTNTLQALQALAKFHRQRFSIPLVAVTGSNGKTTTKD
MLAAVLSGRFKVLKTEANFNNEIGLSLTLLQLEPSHEAAVVEMGMRARGEIHALTEIALP
TVGVVTNVGETHMEILGSIENIAAAKAELVEAIGHDDLVVLNGDDPHVRAMQRKAQGRVV
LYGLHPDAFVRAENIVTGKDGELITTFDCCSPRGSFPVTLAAVGIHNVYNALAAIATGWE
LGLKPSEIKAGITSFVPGAMRLEVKRYGDITVINDVYNASPLSMAAALNTLTAVSKGRKI
AVLGDMLELGDAAVEAHRRIGRQAAENEVAILISVGEMAKHIAAAARESGVKTTYSFAGH
QEAIEVLRQVIQPGDCILLKGSRGMKMETMLHTFQDKSLS
NT seq
1383 nt
NT seq
+upstream
nt +downstream
nt
atggctgatttcagtgtaagcgaaattctcaaggcaacaggcggacatttgcttcatgcc
ggcgacaagaaggtgtttcgcggtgtgtctactgacacgagaaatataaaatcaagcaat
ttgtttatcgctctcgtcggtgaacggtttgacggtaatgattttgttgctcaggctgca
gccaaaggagcagccggtctactagtcagcagggcagtaagtgtaccggcaggggtaact
gttatacaagtaaccaataccttacaagctttgcaggcattagcgaagtttcatcgtcag
cgcttttctattccgctggttgctgtgacaggttctaatggcaagacgaccaccaaggac
atgctggctgcggtattatcaggcaggttcaaggttcttaaaaccgaggccaattttaat
aatgaaatcggtttgtcgcttaccctgttacaactggaaccaagccacgaagccgctgtg
gttgagatggggatgcgcgcccggggggaaattcacgcccttactgagattgcgttgcct
acggtgggagttgtgacaaacgtaggcgaaacccatatggaaattcttggttccattgaa
aatatcgctgctgccaaggcagaactagtggaagcaattggtcacgatgacttggttgta
cttaatggcgatgatcctcatgtacgagctatgcagcgtaaggcacaaggaagagttgtc
ctttacggcttacatcctgacgcctttgttcgggctgaaaatatagttaccggcaaagac
ggtgaattaataactacctttgactgttgcagcccgcgcggttcttttcctgttacgtta
gcagcggtcggcatccacaatgtttacaatgcgctggcggcgattgcaacaggctgggaa
ttggggctgaaaccaagtgaaataaaagccgggataacgagctttgtcccgggtgccatg
cggctggaagttaaaaggtacggcgatattaccgtaattaatgatgtatataatgccagt
ccgttatccatggcagcggctttaaacacgttgacggccgtcagcaaaggcagaaaaatt
gccgtacttggcgatatgctggaattaggtgatgccgctgttgaagctcaccggcgaatc
ggcaggcaagcggcggaaaacgaagtggcgattcttatatcggtgggagaaatggcaaaa
catattgctgctgctgctcgcgagagcggtgtgaaaactacgtattcctttgccgggcat
caagaggccattgaggtacttcgccaggttatccagcctggagattgtattctacttaag
ggctctcgcggtatgaaaatggaaactatgctacatacatttcaagacaaatcgctttca
tag
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