Staphylococcus aureus subsp. aureus Newman: NWMN_1114
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Entry
NWMN_1114 CDS
T00557
Symbol
pyrAB
Name
(GenBank) carbamoyl-phosphate synthase, pyrimidine-specific, large chain
KO
K01955
carbamoyl-phosphate synthase large subunit [EC:
6.3.5.5
]
Organism
sae
Staphylococcus aureus subsp. aureus Newman
Pathway
sae00220
Arginine biosynthesis
sae00240
Pyrimidine metabolism
sae00250
Alanine, aspartate and glutamate metabolism
sae01100
Metabolic pathways
sae01110
Biosynthesis of secondary metabolites
sae01240
Biosynthesis of cofactors
Brite
KEGG Orthology (KO) [BR:
sae00001
]
09100 Metabolism
09104 Nucleotide metabolism
00240 Pyrimidine metabolism
NWMN_1114 (pyrAB)
09105 Amino acid metabolism
00250 Alanine, aspartate and glutamate metabolism
NWMN_1114 (pyrAB)
00220 Arginine biosynthesis
NWMN_1114 (pyrAB)
Enzymes [BR:
sae01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.5 Carbon-nitrogen ligases with glutamine as amido-N-donor
6.3.5.5 carbamoyl-phosphate synthase (glutamine-hydrolysing)
NWMN_1114 (pyrAB)
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Gene cluster
GFIT
Motif
Pfam:
CPSase_L_D2
CPSase_L_D3
MGS
Dala_Dala_lig_C
ATP-grasp_3
ATP-grasp
GARS_A
ATPgrasp_Ter
ATP-grasp_4
ATP-grasp_5
RimK
ATP-grasp_2
Motif
Other DBs
NCBI-ProteinID:
BAF67386
UniProt:
A6QGA4
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Position
1218907..1222080
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AA seq
1057 aa
AA seq
DB search
MPKRNDIKTILVIGSGPIIIGQAAEFDYAGTQACLALKEEGYRVILVNSNPATIMTDKEI
ADKVYIEPLTHDFIARIIRKEQPDALLPTLGGQTGLNMAIQLHESGVLQDNNVQLLGTEL
TSIQQAEDREMFRTLMNDLNVPVPESDIVNTVEQAFKFKEQVGYPLIVRPAFTMGGTGGG
ICHNDEELHEIVSNGLHYSPATQCLLEKSIAGFKEIEYEVMRDKNDNAIVVCNMENIDPV
GIHTGDSIVVAPSQTLSDVEYQMLRDVSLKVIRALGIEGGCNVQLALDPHSFDYYIIEVN
PRVSRSSALASKATGYPIAKLAAKIAVGLTLDEMLNPITGTSYAAFEPTLDYVISKIPRF
PFDKFEKGERELGTQMKATGEVMAIGRTYEESLLKAIRSLEYGVHHLGLPNGESFDLDYI
KERISHQDDERLFFIGEAIRRGTTLEEIHNMTQIDYFFLHKFQNIIDIEHQLKEHQGDLE
YLKYAKDYGFSDKTIAHRFNMTEEEVYQLRMENDIKPVYKMVDTCAAEFESSTPYYYGTY
ETENESIVTDKEKILVLGSGPIRIGQGVEFDYATVHAVWAIQKAGYEAIIVNNNPETVST
DFSISDKLYFEPLTEEDVMNIINLEKPKGVVVQFGGQTAINLADKLAKHGVKILGTSLEN
LNRAEDRKEFEALLRKINVPQPQGKTATSPEEALANAAEIGYPVVVRPSYVLGGRAMEIV
DNDKELENYMTQAVKASPEHPVLVDRYLTGKEIEVDAICDGETVIIPGIMEHIERAGVHS
GDSIAVYPPQTLTEDELATLEDYTIKLAKGLNIIGLINIQFVIAHDGVYVLEVNPRSSRT
VPFLSKITDIPMAQLAMRAIIGEKLTDMGYQEGVQPYAEGVFVKAPVFSFNKLKNVDITL
GPEMKSTGEVMGKDTTLEKALFKGLTGSGVEVKDHGTVLMTVSDKDKEEVVKLAQRLNEV
GYKILATSGTANKLAEYDIPAEVVGKIGGENDLLTRIQNGDVQIVINTMTKGKEVERDGF
QIRRTTVENGIPCLTSLDTANALTNVIESMTFTMRQM
NT seq
3174 nt
NT seq
+upstream
nt +downstream
nt
atgcctaaacgtaatgatatcaaaacaattttagtaatagggtctgggccaattatcata
ggtcaagcagctgaatttgattatgctggaacacaagcatgtctagctttaaaagaagag
ggatatcgagttattcttgtaaattcaaatccagcgacaatcatgactgataaggaaatt
gcggataaagtatatatcgaaccgttaactcatgattttatagcgcgaattatacgtaaa
gagcaacctgacgctttacttccaactttaggtggtcaaacaggtttaaacatggcgatt
caactacacgaaagtggtgtgcttcaagataataacgtccaattattaggaactgagcta
acatcaattcaacaagcagaagaccgtgaaatgtttagaacattaatgaatgatttaaac
gttcctgtaccagagagtgacattgtaaatacagtagagcaagcctttaaattcaaagag
caagtgggatacccgctaattgttagaccggcatttacgatgggtggtaccggaggcggt
atttgtcataatgatgaagaattacatgaaatcgtctcaaatggtcttcattatagtcca
gcaacgcaatgtttattagaaaaatctatcgcaggttttaaagaaatcgaatacgaagta
atgcgtgataaaaacgataatgccatcgttgtatgtaacatggaaaatattgatccagtt
ggtattcatacaggcgattcaattgttgtggctcctagtcaaacattatcagatgttgag
tatcaaatgttacgtgatgtttcattaaaagttattcgagctttaggtatcgaaggtggt
tgtaatgttcaattagcattagatccccattcattcgattattatattatagaagtaaat
ccgcgtgtatcacgttcatcagcgttagcttcaaaagcaacaggatatcctattgcaaaa
ttagctgctaaaatcgcggttggtctaacattagatgaaatgttaaatccaattacagga
acatcttatgcagcgtttgaaccaactttagactatgtgatttcaaaaataccaagattt
ccttttgataaatttgaaaaaggagaacgagagcttggcacacaaatgaaagcaacaggt
gaagttatggccattggtcgaacttacgaagaatcattgttaaaagcaattcgatcactt
gagtatggtgtgcatcacttaggattaccaaatggtgaaagcttcgatcttgattatatt
aaagaacgtatttcacaccaagatgatgaacgattatttttcatcggcgaagcaattaga
agaggcacaacattagaagaaattcataatatgactcagattgattacttcttcttacac
aagttccaaaacattattgatattgagcatcaattaaaagagcatcaaggtgatttagaa
tatcttaaatatgcaaaagattatggatttagtgataaaacaatagcgcatcgctttaat
atgacggaagaagaagtatatcaattgcgtatggaaaatgatattaaacctgtttacaag
atggttgatacttgcgcagctgaatttgaatcttcaacaccatattattatggtacatac
gaaactgaaaatgaatccatagttactgacaaagaaaaaatcttagtattaggctctgga
ccaattcgaatcggccaaggtgtagaatttgactatgcgacagttcatgccgtttgggca
attcaaaaagcagggtacgaagcgataattgtgaataacaatccagaaacagtttcaaca
gacttctcaatttctgacaaattatactttgaacctttaactgaagaagatgtgatgaat
atcattaatttagaaaaacctaaaggtgtcgttgtacaatttggaggacaaacagcgatt
aatttagcagacaaattggctaaacatggtgttaaaatacttggtacttcactagaaaat
ctaaatcgtgctgaagatagaaaagaatttgaagcactattaagaaaaattaacgtgcca
cagccacaagggaaaacagctacatcacctgaggaagcattagcgaatgctgcagaaatc
ggatatccggttgtagtaagaccttcttatgtattaggtggtcgcgcaatggaaattgta
gacaatgacaaagagttagaaaactatatgacccaggctgtaaaagcgagtccggaacat
ccggtactagtcgatagatatttaactggtaaagaaattgaagttgatgcgatttgtgat
ggagaaacggtcattattccaggaatcatggaacatattgaacgtgctggtgtgcatagt
ggtgactcaatcgctgtatatccaccacaaactttgacagaagacgagttagcaacactt
gaggactatactataaaattagctaaaggtttaaacatcattggcttaatcaacattcaa
ttcgttatagctcacgatggtgtgtatgttttagaagtaaatccacgttctagtagaacg
gtaccattcttaagtaaaattactgatattccaatggcacaattagctatgcgagcaatc
attggggaaaaactaacagatatgggttatcaagaaggggttcaaccatatgctgagggt
gtctttgtgaaagcaccagtatttagttttaataaattgaaaaatgttgatattacttta
ggacctgaaatgaagtcaacaggtgaagtgatggggaaagatactacattagaaaaggcg
ttattcaaagggttaacaggtagtggcgttgaagttaaagatcacggtacagtattaatg
accgtcagtgacaaagataaagaggaagttgttaaattggcacaacgcttaaatgaagtt
ggctataaaattttagcaacgtctggaacagctaataaattagctgagtatgacatacct
gcagaagtagtaggcaaaattggtggcgaaaatgatttattaacacgtattcaaaatggt
gatgttcaaatcgttataaatacaatgactaaaggtaaagaagtagaaagggatggcttc
caaattagacgtactacagttgaaaatggtattccatgtttgacatctttagatacagct
aatgccttaacgaatgtaattgaaagtatgacatttacaatgcgtcaaatgtaa
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