Staphylococcus aureus subsp. aureus Newman: NWMN_1965
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Entry
NWMN_1965 CDS
T00557
Symbol
leuC
Name
(GenBank) 3-isopropylmalate dehydratase, large subunit
KO
K01703
3-isopropylmalate/(R)-2-methylmalate dehydratase large subunit [EC:
4.2.1.33
4.2.1.35
]
Organism
sae
Staphylococcus aureus subsp. aureus Newman
Pathway
sae00290
Valine, leucine and isoleucine biosynthesis
sae00660
C5-Branched dibasic acid metabolism
sae01100
Metabolic pathways
sae01110
Biosynthesis of secondary metabolites
sae01210
2-Oxocarboxylic acid metabolism
sae01230
Biosynthesis of amino acids
Module
sae_M00432
Leucine biosynthesis, 2-oxoisovalerate => 2-oxoisocaproate
Brite
KEGG Orthology (KO) [BR:
sae00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00660 C5-Branched dibasic acid metabolism
NWMN_1965 (leuC)
09105 Amino acid metabolism
00290 Valine, leucine and isoleucine biosynthesis
NWMN_1965 (leuC)
Enzymes [BR:
sae01000
]
4. Lyases
4.2 Carbon-oxygen lyases
4.2.1 Hydro-lyases
4.2.1.33 3-isopropylmalate dehydratase
NWMN_1965 (leuC)
4.2.1.35 (R)-2-methylmalate dehydratase
NWMN_1965 (leuC)
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Motif
Pfam:
Aconitase
Motif
Other DBs
NCBI-ProteinID:
BAF68237
UniProt:
A6QIQ5
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All DBs
Position
2176954..2178324
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AA seq
456 aa
AA seq
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MGQTLFDKVWNRHVLYGKLGEPQLLYIDLHLIHEVTSPQAFEGLRLQNRKLRRPDLTFAT
LDHNVPTIDIFNIKDEIANKQITTLQKNAIDFGVHIFDMGSDEQGIVHMVGPETGLTQPG
KTIVCGDSHTATHGAFGAIAFGIGTSEVEHVFATQTLWQTKPKNLKIDINGTLPTGVYAK
DIILHLIKTYGVDFGTGYALEFTGETIKNLSMDGRMTICNMAIEGGAKYGIIQPDDITFE
YVKGRPFADNFAKSVDKWRELYSDDDAIFDRVIELDVSTLEPQVTWGTNPEMGVNFSEPF
PEINDINDQRAYDYMGLEPGQKAEDIDLGYVFLGSCTNARLSDLIEASHIVKGNKVHPNI
TAIVVPGSRTVKKEAEKLGLDTIFKNAGFEWREPGCSMCLGMNPDQVPEGVHCASTSNRN
FEGRQGKGARTHLVSPAMAAAAAIHGKFVDVRKVVV
NT seq
1371 nt
NT seq
+upstream
nt +downstream
nt
atgggtcaaacattatttgacaaggtgtggaacagacatgtgttatacgggaaattgggc
gaaccgcaactattatacattgatttacaccttatacatgaagttacttctcctcaagca
tttgaaggacttaggcttcaaaacagaaaattaagacgcccagatttaacatttgcaaca
ctcgatcacaatgttcctactattgatatattcaatattaaagatgaaattgcaaacaaa
caaatcacaacattacaaaaaaacgccatagattttggggtgcatatttttgatatgggt
tctgatgaacaaggtattgttcacatggtaggacctgagacaggacttacacagcctggc
aagacaatcgtttgtggtgactctcacacagcaacacatggagcatttggtgctattgca
tttggaattggaacaagtgaagttgaacatgttttcgcaactcaaacgctatggcaaaca
aaacccaaaaacttaaaaatcgatattaatggtaccttaccaacaggcgtctatgctaag
gacattattctgcatttaattaaaacgtatggtgttgactttggtacaggctatgctttg
gaatttactggcgaaacaattaaaaacctttcaatggatggtcgaatgactatttgtaac
atggctatcgaaggtggtgccaaatacggcataatccaacctgatgatataacatttgaa
tatgttaaagggagaccatttgccgataacttcgctaaatcagttgataagtggcgtgag
ctatattctgatgacgacgcgatatttgatcgtgtaattgaacttgatgtttcaacatta
gaaccacaagtgacatggggaactaatcctgaaatgggtgttaatttcagtgaaccattc
cctgaaatcaatgatatcaacgatcaacgtgcgtatgattatatggggttagaaccaggt
caaaaagctgaagacatcgacttagggtatgtttttctcggttcatgtacaaatgctaga
ctatcagatttgattgaagctagtcatattgttaaaggaaataaagttcatccaaatatt
acagctattgtcgtaccaggttctcgtacagtaaaaaaagaagcagaaaaattaggtcta
gatactatctttaaaaatgcaggatttgaatggcgtgaaccaggatgttcaatgtgttta
ggcatgaatcctgaccaagtacctgagggcgtacattgtgcatctacaagtaatcgaaac
tttgaaggacgacaaggcaaaggtgcaagaacacatttagtatcccctgctatggcagca
gcagcagctattcatggtaaatttgtggacgtaagaaaggtggttgtttaa
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