Streptococcus agalactiae 2603 (serotype V): SAG0768
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Entry
SAG0768 CDS
T00091
Symbol
murF
Name
(GenBank) UDP-N-acetylmuramoylalanyl-D-glutamyl-2,6-diaminopimelate--D-alanyl-D-alanyl ligase
KO
K01929
UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase [EC:
6.3.2.10
]
Organism
sag
Streptococcus agalactiae 2603 (serotype V)
Pathway
sag00300
Lysine biosynthesis
sag00550
Peptidoglycan biosynthesis
sag01100
Metabolic pathways
sag01502
Vancomycin resistance
Brite
KEGG Orthology (KO) [BR:
sag00001
]
09100 Metabolism
09105 Amino acid metabolism
00300 Lysine biosynthesis
SAG0768 (murF)
09107 Glycan biosynthesis and metabolism
00550 Peptidoglycan biosynthesis
SAG0768 (murF)
09160 Human Diseases
09175 Drug resistance: antimicrobial
01502 Vancomycin resistance
SAG0768 (murF)
Enzymes [BR:
sag01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.2 Acid-D-amino-acid ligases (peptide synthases)
6.3.2.10 UDP-N-acetylmuramoyl-tripeptide---D-alanyl-D-alanine ligase
SAG0768 (murF)
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Gene cluster
GFIT
Motif
Pfam:
Mur_ligase_M
Mur_ligase_C
Mur_ligase
Motif
Other DBs
NCBI-ProteinID:
AAM99655
UniProt:
Q8E0G5
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All DBs
Position
764727..766094
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AA seq
455 aa
AA seq
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MKLSLHEVAKVVGAKNQVSEFEDVPLGNIEFDSRNISEGDLFLPLKGARDGHEFIEMAFD
NGAIATISEKEIEGHPYLLVSDALKAFQVLAQYYIEKMNVDVIAVTGSNGKTTTKDMIAA
ILSTTYKTYKTQGNYNNEIGLPYTVLHMPEDTEKIILEMGQDHLGDIHVLSEIAKPRIAV
VTLIGEAHLEFFGSREKIAEGKMQITDGMSSDGILIAPGDPIIDPYLPANQMTIRFGHDQ
ELQVTELKEEKHSLTFKTNALEHQLRIPVPGKYNATNAMVAAYVGKLLAVAEEDIVDALE
NLQLTRNRTEWKKSANGADILSDVYNANPTAMRLILETFSAIPNNDGGKKIALLADMKEL
GEQSVDLHNQMIMSIRPDSIDTLICYGQDIEGLAQLASQMFPIGKVYFFKKNQEVDQFDQ
LLAKVKDTLKEKDQILLKGSNSMNLSKIVDILEVG
NT seq
1368 nt
NT seq
+upstream
nt +downstream
nt
atgaagcttagtttgcatgaagttgctaaagtagttggcgctaaaaatcaagtatcagag
tttgaagacgttcccctgggaaatattgaatttgatagtcgtaatatcagtgaaggtgac
ttatttcttcccttaaaaggagcaagagatggacatgagtttatagagatggcttttgat
aatggagcaatagcaaccatttcagagaaggaaatagagggtcatccttatcttttagtg
tctgatgcacttaaagcatttcaagtcttggcacagtattatattgaaaagatgaacgtt
gatgttattgcagtaactggctcaaatggtaagacaacaactaaagatatgatagctgca
atcttatcaaccacatataagacttataaaacacaaggaaactacaataacgagattggc
ttaccctatactgtgctacacatgccagaagatactgaaaaaattattttggagatggga
caggatcatcttggagatatccatgtgttatctgaaattgcaaaaccacgtattgctgtt
gttactttgattggtgaagcacacttagaattttttggtagtcgagaaaagattgcagaa
gggaaaatgcaaatcacagatggtatgagttcagatggcatattaattgcaccgggagat
ccaattattgatccatatcttccagcaaaccagatgactattcgttttggtcatgaccaa
gaattgcaagtgacagaactcaaagaagaaaaacattccttaacttttaaaactaatgct
ttggagcaccaattacgtataccagtacctggtaagtacaatgcaactaatgcgatggtc
gctgcctatgttggaaaattattagcagtagcagaagaagatatagtggatgctctagaa
aatcttcaactaactcgtaatcgcaccgaatggaagaaatcagccaatggagcagatatt
ttatcagatgtttacaatgctaacccaacggctatgcgattgatactagaaaccttttca
gctattcccaataatgatggtggaaagaagattgctcttttagctgatatgaaagaactg
ggagaacaatctgtggatttacataatcaaatgattatgagtatcagacctgactctatt
gatactttgatttgttatggccaggatattgaggggttggctcaattagcaagccagatg
ttcccaattggtaaagtgtatttctttaaaaagaatcaagaagtagatcagtttgatcaa
ttgcttgcaaaagtaaaagatactcttaaggagaaagatcaaatattattaaaaggttct
aactcaatgaatctttctaaaatagttgatattcttgaagtaggataa
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