Streptococcus agalactiae NGBS572: EN73_08925
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Entry
EN73_08925 CDS
T03517
Name
(GenBank) bifunctional glutamate--cysteine ligase/glutathione synthetase
KO
K01919
glutamate--cysteine ligase [EC:
6.3.2.2
]
Organism
sagg
Streptococcus agalactiae NGBS572
Pathway
sagg00270
Cysteine and methionine metabolism
sagg00480
Glutathione metabolism
sagg01100
Metabolic pathways
sagg01240
Biosynthesis of cofactors
Brite
KEGG Orthology (KO) [BR:
sagg00001
]
09100 Metabolism
09105 Amino acid metabolism
00270 Cysteine and methionine metabolism
EN73_08925
09106 Metabolism of other amino acids
00480 Glutathione metabolism
EN73_08925
Enzymes [BR:
sagg01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.2 Acid-D-amino-acid ligases (peptide synthases)
6.3.2.2 glutamate---cysteine ligase
EN73_08925
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Gene cluster
GFIT
Motif
Pfam:
Glu_cys_ligase
ATP-grasp_6
RimK
GARS_A
Dala_Dala_lig_C
ATP-grasp_3
ATP-grasp_4
ATPgrasp_ST
CPSase_L_D2
ATP-grasp
Motif
Other DBs
NCBI-ProteinID:
AIF89308
UniProt:
A0AAW6XVV6
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Position
1744352..1746604
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AA seq
750 aa
AA seq
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MIIDRLLQRSHSHLPILQATFGLERESLRIHQPTQRVAQTPHPKTLGSRNYHPYIQTDYS
EPQLELITPIAKDSQEAIRFLKAISDVAGRSINHDEYLWPLSMPPKVREEDIQIAQLEDA
FEYDYRKYLEKTYGKLIQSISGIHYNLGLGQELLTSLFELSQADNAIDFQNQLYMKLSQN
FLRYRWLLTYLYGASPVAEEDFLDQKLNNPVRSLRNSHLGYVNHKDIRISYTSLKDYVND
LENAVKSGQLIAEKEFYSPVRLRGSKACRNYLEKGITYLEFRTFDLNPFSPIGITQETVD
TVHLFLLALLWIDSSSHIDQDIKEANRLNDLIALSHPLEKLPNQAPVSDLVDAMQSVIQH
FNLSPYYQDLLESVKRQIQSPELTVAGQLLEMIEGLSLETFGQRQGQIYHDYAWEAPYAL
KGYETMELSTQLLLFDVIQKGVNFEVLDEQDQFLKLWHNSHIEYVKNGNMTSKDNYIVPL
AMANKVVTKKILDEKHFPTPFGDEFTDRKEALNYFSQIQDKPIVVKPKSTNFGLGISIFK
TSANLASYEKAIDIAFTEDSAILVEEYIEGTEYRFFVLEGDCIAVLLRVAANVVGDGIHT
ISQLVKLKNQNPLRGYDHRSPLEVIELGEVEQLMLEQQGYTVNSIPPEGTKIELRRNSNI
STGGDSIDVTNTMDPTYKQLAAEMAEAMGAWVCGVDLIIPNATQAYSKDKKNATCIELNF
NPLMYMHTYCQEGPGQSITPRILAKLFPEL
NT seq
2253 nt
NT seq
+upstream
nt +downstream
nt
gtgattatcgatcgactgttacaaagaagccactctcatctaccgattctacaagctaca
tttggcttagagagagaaagccttcgtattcaccaacccactcaaagggttgctcaaaca
ccccatcccaaaacattagggagtcgtaactatcatccttatatccaaacggattatagt
gaacctcaattagaactcattacacctattgcaaaggatagccaagaagccattcgattt
ttgaaagctataagtgatgttgctggacgctctatcaaccacgatgaatacttatggccg
ctttctatgccacccaaagtgagggaagaagacatacagattgcccaattagaggatgct
tttgaatatgattatcgcaaatatttggagaagacttatggaaaactaatacaatccatc
tctggaattcactataatctcggtttaggtcaagagttattaacttctctctttgaattg
agtcaagcagataatgctattgattttcagaaccagctttacatgaaattgtctcaaaat
tttttacgttaccgttggttactaacttatctatacggagcgagcccagtagctgaagaa
gactttttagatcagaaactgaataaccctgtccggtcacttagaaatagtcacttaggt
tatgtgaatcataaagatattcgtatttcttatactagcttgaaggattatgtcaacgat
ctagaaaatgctgtaaaaagtgggcaattgattgctgagaaagaattttattcacctgtt
cgtctccgtggtagtaaggcctgtcgtaattatttagaaaaaggaattacatatttagag
tttcgcacttttgatctcaacccatttagcccaatcggtataacgcaggaaactgttgat
actgttcaccttttcttattggcgcttttgtggatagattctagtagtcatattgaccaa
gatatcaaggaagccaatagattaaatgaccttatagcacttagtcatccattagaaaaa
ttacctaatcaagcaccagtttctgacttagtggatgctatgcaatctgttatccaacat
tttaacttatcaccttactatcaagacctattggaatctgtaaaaaggcaaattcagtca
cctgaattaacggtagctggtcaacttttagaaatgattgaaggactttccttagaaaca
tttggacaaagacaaggacaaatttatcacgattatgcttgggaagctccctacgcctta
aagggatatgaaacgatggaactttctacccaattgctactatttgacgttatccaaaaa
ggagtcaacttcgaagtgctggatgaacaagatcaattcctaaaattatggcacaatagt
catattgagtacgttaaaaatggtaatatgacctcaaaagataactatattgtaccgctc
gctatggctaacaaagttgttacaaaaaaaatcctagatgaaaagcatttcccaactcct
tttggagatgaatttactgaccgtaaagaggcacttaactatttttcacaaatccaagat
aagccaatcgtcgttaagccaaaatctacaaactttggtttaggcatttctatttttaaa
acatcagctaacttagcttcttatgaaaaagcaattgacatcgcttttaccgaagatagt
gctattcttgtggaagaatatattgagggtaccgaataccgtttcttcgtccttgagggg
gactgtattgctgtattgcttagggtagcagctaatgtcgttggagatggtattcatact
attagtcagctagttaaacttaaaaaccaaaaccctctcagaggctatgatcatcgctct
cctctagaagttattgagctcggagaagtagaacagttaatgttggaacaacaaggatac
actgttaacagtatccctccagaaggaacaaaaatagaacttcgccgtaattctaatatt
tccactggcggtgactctatagatgtaacaaatacaatggatcctacatataaacaacta
gcagctgagatggcagaggctatgggggcttgggtttgtggagttgatttaattattcct
aatgccactcaagcatactcaaaagataagaaaaatgctacttgcattgaactaaacttt
aacccattgatgtatatgcacacctactgtcaagaggggcctggtcaatctattacacct
cgaattttggctaaactgttcccagaattataa
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