Streptococcus agalactiae 2-22 (serotype Ib): GBS222_0641
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Entry
GBS222_0641 CDS
T02656
Symbol
murF
Name
(GenBank) UDP-N-acetylmuramoylalanyl-D-glutamyl-2,6-diamino pimelate-D-alanyl-D-alanyl ligase
KO
K01929
UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase [EC:
6.3.2.10
]
Organism
sagl
Streptococcus agalactiae 2-22 (serotype Ib)
Pathway
sagl00300
Lysine biosynthesis
sagl00550
Peptidoglycan biosynthesis
sagl01100
Metabolic pathways
sagl01502
Vancomycin resistance
Brite
KEGG Orthology (KO) [BR:
sagl00001
]
09100 Metabolism
09105 Amino acid metabolism
00300 Lysine biosynthesis
GBS222_0641 (murF)
09107 Glycan biosynthesis and metabolism
00550 Peptidoglycan biosynthesis
GBS222_0641 (murF)
09160 Human Diseases
09175 Drug resistance: antimicrobial
01502 Vancomycin resistance
GBS222_0641 (murF)
Enzymes [BR:
sagl01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.2 Acid-D-amino-acid ligases (peptide synthases)
6.3.2.10 UDP-N-acetylmuramoyl-tripeptide---D-alanyl-D-alanine ligase
GBS222_0641 (murF)
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GFIT
Motif
Pfam:
Mur_ligase_M
Mur_ligase_C
Mur_ligase
Motif
Other DBs
NCBI-ProteinID:
CCO74417
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Position
675898..677265
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AA seq
455 aa
AA seq
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MKLSLHEVAKVVGAKNQVSEFEDVPLGNIEFGSRNISEGDLFLPLKGARDGHEFIEMAFD
NGAIATISEKEIEGHPYLLVSDALKAFQVLAQYYIEKMNVDVIAVTGSNGKTTTKDMIAA
ILSTTYKTYKTQGNYNNEIGLPYTVLHMPEDTEKIVLEMGQDHLGDIYVLSEIAKPRIAV
VTLIGEAHLEFFGSREKIAEGKMQITDGMSSDGILIAPGDPIIDPYLPANQMTIRFGHDQ
ELQVTELKEEKHSLTFKTNALEHQLRIPVPGKYNATNAMVAAYVGKLLAVAEEDIVDALE
NLQLTRNRTEWKKSANGADILSDVYNANPTAMRLILETFSAIPNNDGGKKIALLADMKEL
GEQSVDLHNQMIMSIRPDSIDTLICYGQDIEGLAQLASQMFPIGKVYFFKKNQEVDQFDQ
LLAKVKDTLKEKDQILLKGSNSMNLSKIVDILEVG
NT seq
1368 nt
NT seq
+upstream
nt +downstream
nt
atgaagcttagtttgcatgaagttgctaaagtagttggcgctaaaaatcaagtatcagag
tttgaagacgttcccctgggaaatattgaatttggtagtcgtaatatcagtgaaggtgac
ttatttcttcccttaaaaggagcaagagatggacatgagtttatagagatggcttttgat
aatggagcaatagcaaccatttcagagaaggaaatagagggtcatccttatcttttagtg
tctgatgcacttaaagcatttcaagtcttggcacagtattatattgaaaagatgaacgtt
gatgttattgcagtaactggctcaaatggtaagacaacaactaaagatatgatagctgca
atcttatcaaccacatataagacttataaaacacaaggaaactacaataacgagattggc
ttaccatatactgtgctacacatgccagaagatactgaaaaaattgttttggagatggga
caggatcatcttggagatatctatgtgttatctgaaattgcaaaaccacgtattgctgtt
gttactttgattggtgaagcacacttagaattttttggtagtcgagaaaagattgcagaa
gggaaaatgcaaatcacagatggtatgagttcagatggcatattaattgcaccgggagat
ccaattattgatccatatcttccagcaaaccagatgactattcgttttggtcatgaccaa
gaattgcaggtgacagaactcaaagaagaaaaacattccttaacttttaaaactaatgct
ttggagcaccaattacgtataccagtacctggtaagtacaatgcaactaatgcgatggtc
gctgcctatgttggaaaattattagcagtagcagaagaagatatagtggatgctctagaa
aatcttcaactaactcgtaatcgcaccgaatggaagaaatcagccaatggagcagatatt
ttatcagatgtttacaatgctaacccaacggctatgcgattgatactagaaaccttttca
gctattccgaataatgatggtggaaagaagattgctcttttagctgatatgaaagaactg
ggagaacaatctgtggatttacataatcaaatgattatgagtatcagacctgactctatt
gatactttgatttgttatggccaggatattgaggggttggctcaattagcaagccagatg
ttcccaattggtaaagtgtatttctttaaaaagaatcaagaagtggatcagtttgatcaa
ttgcttgcaaaagtaaaagatactcttaaggagaaagatcaaatattattaaaaggttct
aactcaatgaatctttctaaaatagttgatattcttgaagtaggataa
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