Sulfolobus acidocaldarius DSM 639: Saci_0600
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Entry
Saci_0600 CDS
T00251
Symbol
leuB
Name
(GenBank) 3-isopropylmalate dehydrogenase
KO
K00052
3-isopropylmalate dehydrogenase [EC:
1.1.1.85
]
Organism
sai
Sulfolobus acidocaldarius DSM 639
Pathway
sai00290
Valine, leucine and isoleucine biosynthesis
sai00660
C5-Branched dibasic acid metabolism
sai01100
Metabolic pathways
sai01110
Biosynthesis of secondary metabolites
sai01210
2-Oxocarboxylic acid metabolism
sai01230
Biosynthesis of amino acids
Module
sai_M00432
Leucine biosynthesis, 2-oxoisovalerate => 2-oxoisocaproate
Brite
KEGG Orthology (KO) [BR:
sai00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00660 C5-Branched dibasic acid metabolism
Saci_0600 (leuB)
09105 Amino acid metabolism
00290 Valine, leucine and isoleucine biosynthesis
Saci_0600 (leuB)
Enzymes [BR:
sai01000
]
1. Oxidoreductases
1.1 Acting on the CH-OH group of donors
1.1.1 With NAD+ or NADP+ as acceptor
1.1.1.85 3-isopropylmalate dehydrogenase
Saci_0600 (leuB)
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Motif
Pfam:
Iso_dh
PdxA
Motif
Other DBs
NCBI-ProteinID:
AAY79992
UniProt:
Q4JB37
Structure
PDB
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Position
complement(480116..481129)
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AA seq
337 aa
AA seq
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MGFVVALIQGDGIGPEVVSKSKTILARLNEKFSLPIEYIEVEAGDTTKNKFGDALPKDSL
RVIEKADMILKGPVGETAADVVVKLRLMYDLYANLRPAKSLPGLENKFGDVDILVVRENT
EDLYKGLEHVISDGVTVGIKVITRAASTRIAQVALNQALRRKKKVVCVHKSNVMRITDGL
FAESCRNVLKGKVEYSEMYVDAAAANLVRNPQAFDVIVTENTYGDILSDEAGQIAGSLGI
SPSANIGDRKSLFEPVHGAAFDIAGKNIANPTAFLLSVGMMLDRMQELSGDIRYNNAAKS
LRDAIYSVYSEGKYLTPDVGGSSTTDEMISAIRSKIG
NT seq
1014 nt
NT seq
+upstream
nt +downstream
nt
atgggttttgttgtagcattaattcaaggggacggcataggtccggaagttgttagcaaa
tcaaaaaccatattagctaggttaaatgaaaaattcagtctccccatagaatatattgag
gtagaagctggagatactactaaaaataagttcggtgatgcattacctaaagactcatta
agagtaatagagaaagctgatatgattttgaagggtcccgtgggcgagactgctgctgat
gttgtagttaagctaagacttatgtacgatttatatgcaaatttaagacctgctaaatct
cttcctggtctagaaaataaattcggagatgttgatatcttagtagttagagagaataca
gaagacctatacaagggtttagaacatgttatctctgatggagttacagtgggtattaaa
gttataactcgcgccgcctcgacaagaatagctcaagttgcactaaatcaagcattgaga
agaaagaaaaaggtagtttgtgtccataaatcgaatgttatgagaattacagatgggttg
tttgcggaatcatgtagaaatgtattgaaaggaaaagtggagtattctgaaatgtatgtt
gacgctgctgctgcaaacttagttaggaatcctcaagcattcgatgtaatagttactgag
aatacttacggcgatatattaagtgatgaggcaggccaaatagcaggtagtctaggtata
tccccttcagctaatatcggtgacaggaagtctttgtttgagccagtacatggtgcagca
ttcgatattgctggcaagaatatagctaatcccactgctttccttttatcagtaggaatg
atgttagatagaatgcaagaactctcgggcgacataagatacaataatgcagctaaatct
ttgcgagacgctatatattcagtgtattctgaagggaaatatctaacgcctgatgtaggt
ggaagttctacaacagatgaaatgataagcgcaatacggagtaaaataggttaa
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