Streptomyces akebiae: K1J60_27130
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Entry
K1J60_27130 CDS
T08702
Name
(GenBank) uroporphyrinogen-III synthase
KO
K01719
uroporphyrinogen-III synthase [EC:
4.2.1.75
]
Organism
sakb
Streptomyces akebiae
Pathway
sakb00860
Porphyrin metabolism
sakb01100
Metabolic pathways
sakb01110
Biosynthesis of secondary metabolites
sakb01120
Microbial metabolism in diverse environments
sakb01240
Biosynthesis of cofactors
Module
sakb_M00121
Heme biosynthesis, plants and bacteria, glutamate => heme
sakb_M00846
Siroheme biosynthesis, glutamyl-tRNA => siroheme
sakb_M00926
Heme biosynthesis, bacteria, glutamyl-tRNA => coproporphyrin III => heme
Brite
KEGG Orthology (KO) [BR:
sakb00001
]
09100 Metabolism
09108 Metabolism of cofactors and vitamins
00860 Porphyrin metabolism
K1J60_27130
Enzymes [BR:
sakb01000
]
4. Lyases
4.2 Carbon-oxygen lyases
4.2.1 Hydro-lyases
4.2.1.75 uroporphyrinogen-III synthase
K1J60_27130
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Gene cluster
GFIT
Motif
Pfam:
HEM4
Trans_reg_C
Motif
Other DBs
NCBI-ProteinID:
QYX79703
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Position
6305102..6306292
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AA seq
396 aa
AA seq
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MDRTDRTDRTDRTDRADRVAQTEHGPLAGFTVGVTAARRADELGALLQRRGAAVLHAPAL
RIVPLADDSELLAATKGLLDQAPDIVVATTAIGFRGWVEAADGWGLGEALLDRLRGVEVL
ARGPKVKGAIRAAGLTEEWSPSSESMAEVLDRLLEQGVEGRRIAVQLHGEPLPGFVESLR
AGGAEVVGVPVYRWMPPEDITPVDRLLDATVGRGVDALTFTSAPAAASLLSRAEDRGLLP
ELLNALNHDVLPACVGPVTALPLQAHGVDTVQPERFRLGPLVQLLCQELPGRARTLPVAG
HHVEIRGHAVLVDGALRPVPPAGMSLLRALCRRPGWVVPRSDLLRALPGAGRDEHAVETA
MARLRTALGTPKLIQTVVKRGYRLALDPAADAKYDA
NT seq
1191 nt
NT seq
+upstream
nt +downstream
nt
atggaccggacagatcgaacggaccggactgaccgcaccgaccgagcggaccgggtggcg
cagaccgaacacgggccgctcgccggcttcaccgtgggcgtcaccgccgcccgccgggcc
gacgagctcggggcgctgctccagcgccgcggcgccgcggtcctgcacgcccccgcgctg
cgcatcgtgccgctcgccgacgacagcgaactgctcgccgcgaccaagggcctgctcgac
caggcgcccgacatcgtggtggcgacgacggccatcggcttccgcggctgggtcgaggcg
gcggacggctggggcctcggcgaggccctgctcgaccggctgcggggtgtcgaggtcctg
gcccgcggaccgaaggtgaagggcgcgatccgcgccgccggtctcacggaggagtggtcc
ccctcctcggagtccatggccgaggtgctcgaccgtctgctggagcagggggtcgagggc
cgccgcatcgccgtccagctccacggcgaaccgcttcccggcttcgtggagtccctgcgc
gccgggggagcggaggtggtcggcgtccccgtctaccgctggatgccgcccgaggacatc
acccccgtggaccgcctcctcgatgcgacggtcggccgcggcgtcgacgccctcaccttc
accagcgctcccgcggcggcgtccctgctctcccgcgccgaggaccggggcctgctcccg
gagttgctcaacgcgctgaaccacgacgtcctgcccgcctgtgtgggcccggtgaccgcc
ctgccgctccaggcgcacggcgtggacacggtccagcccgaacgcttccgcctcggcccc
ctcgtccaactcctgtgccaggaactccccggccgcgcccgcacgctgcccgtcgccggc
caccatgtggagatccgcggccacgcggtcctcgtcgacggggccctgcgccccgtgccc
ccggccggcatgtccctgctccgcgcgctctgtcgcaggcccggctgggtcgtcccccgc
tccgacctcctgcgcgccctccccggcgcgggccgcgacgaacacgccgtggagacggcg
atggcccgcctccgcacggccctcggcaccccgaaactcatccagaccgtggtcaagcgc
ggctaccgccttgccctggacccggcggcggacgcgaagtacgacgcgtga
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