Streptomyces alboflavus: SMD44_02291
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Entry
SMD44_02291 CDS
T05221
Symbol
murF
Name
(GenBank) UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase
KO
K01929
UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase [EC:
6.3.2.10
]
Organism
salf
Streptomyces alboflavus
Pathway
salf00300
Lysine biosynthesis
salf00550
Peptidoglycan biosynthesis
salf01100
Metabolic pathways
salf01502
Vancomycin resistance
Brite
KEGG Orthology (KO) [BR:
salf00001
]
09100 Metabolism
09105 Amino acid metabolism
00300 Lysine biosynthesis
SMD44_02291 (murF)
09107 Glycan biosynthesis and metabolism
00550 Peptidoglycan biosynthesis
SMD44_02291 (murF)
09160 Human Diseases
09175 Drug resistance: antimicrobial
01502 Vancomycin resistance
SMD44_02291 (murF)
Enzymes [BR:
salf01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.2 Acid-D-amino-acid ligases (peptide synthases)
6.3.2.10 UDP-N-acetylmuramoyl-tripeptide---D-alanyl-D-alanine ligase
SMD44_02291 (murF)
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Motif
Pfam:
Mur_ligase_M
Mur_ligase_C
Mur_ligase
DUF2126
DUF561
Motif
Other DBs
NCBI-ProteinID:
ARX82877
UniProt:
A0A1Z1W8Y7
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All DBs
Position
complement(2474964..2476394)
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AA seq
476 aa
AA seq
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MIALSLAEIATVVGGQTYDIPDPQVQVTAPVVMDSREVEPGGLFAAFVGERVDGHDYAAQ
VVGAGAVAVLASRPCGVPAIVVDDVQTALGALARHVVARLGATLVALTGSAGKTSTKDLI
AQVIGRKAPTVWTPGSFNNEIGLPLTALSATDETKFLVLEMGARGIGHIRYLTGLTPPRI
GLVLNVGTAHIGEFGGREQIAQAKGELVEALPADGAAILNADDPLVRAMASRTKARVLLF
GEAADADVRAENVRLTENGQPAFTLTTPTGCSDVRLRLYGEHHVSNALAAAAVAHELGMS
VDEIALALSEAGTLSRWRMEVTERPDGVTVVNDAYNANPESMRAALRALAAMGRAAQAEG
GRTWAVLGHMAELGDDGLAEHDAVGRLAVRLNVNKLVAVGGREASWLQLGAYNEGSWGEE
SVHVSDAQAAIDLLRSELRPGDVVLVKASRSVGLERVALTLLDDAAASSEGQVAGR
NT seq
1431 nt
NT seq
+upstream
nt +downstream
nt
gtgatcgccctctccctcgccgagatcgccaccgtcgtcggcgggcagacgtacgacata
ccggatccgcaggtccaggtgaccgctccggtcgtcatggactcccgtgaggtggagccc
ggcggcctgttcgccgccttcgtgggcgagcgcgtcgacgggcacgactacgccgcccag
gtcgtgggggcgggcgcggtcgccgtgctcgcctcgcggccgtgcggggtgcccgccatc
gtcgtcgacgacgtgcagacggcgctcggcgccctcgcccggcacgtcgtcgcccggctc
ggcgccaccctcgtcgccctcaccggctccgcgggcaagaccagcaccaaggacctgatc
gcccaggtcatcggccgcaaggcgcccaccgtgtggacgccgggatcgttcaacaacgag
atcggcctgccgctgaccgcgctgagcgccaccgacgagacgaagttcctcgtcctggag
atgggcgcccgcggcatcggccacatccggtacctcaccgggctgacgccgccgcggatc
ggcctcgtcctgaacgtcggcaccgcccacatcggcgagttcggcggccgcgagcagatc
gcgcaagcaaagggcgagctggtcgaggcgctcccggccgacggcgccgcgatcctcaac
gccgacgaccccctcgtacgcgcgatggcctcccgcacgaaggcccgtgtgctgctcttc
ggagaggccgccgacgccgacgtacgtgccgagaatgtccggctcaccgagaacggacag
cccgccttcacgctcaccacacccaccgggtgcagcgacgtgcggctgcgcctgtacggt
gagcaccacgtgtcgaacgcgctcgccgcggccgccgtcgcccatgagctgggcatgtcc
gtggacgagatcgccctcgcgctctccgaggcgggcacgctgtcccgctggcggatggag
gtcaccgagcgcccggacggcgtgacggtcgtcaacgacgcctacaacgcgaaccccgag
tccatgcgagccgccctgcgcgcgctcgcggccatgggcagagccgcgcaggccgagggc
gggcgcacgtgggcggtgctcggtcacatggccgagctcggtgacgacgggctcgccgag
cacgacgcggtcggacgccttgccgtccggctgaacgtgaacaagctcgtggcagtcggg
ggcagggaagcgtcctggctccaactgggcgcatacaacgagggttcgtggggtgaggag
tcggtgcacgtgtccgacgcacaggcggcgatcgacctgctgcgcagcgagctgcgccca
ggagacgtcgtgctggtgaaggcgtccagatcggtcggtctcgagcgggtcgcgctgacg
ctgctcgacgacgccgccgcgtcttcggaggggcaggtcgccggccgatga
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