Salvelinus sp. IW2-2015 (Arctic char): 111968105
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Entry
111968105 CDS
T05762
Name
(RefSeq) glutamate--cysteine ligase catalytic subunit
KO
K11204
glutamate--cysteine ligase catalytic subunit [EC:
6.3.2.2
]
Organism
salp
Salvelinus sp. IW2-2015 (Arctic char)
Pathway
salp00270
Cysteine and methionine metabolism
salp00480
Glutathione metabolism
salp01100
Metabolic pathways
salp01240
Biosynthesis of cofactors
salp04216
Ferroptosis
Module
salp_M00118
Glutathione biosynthesis, glutamate => glutathione
Brite
KEGG Orthology (KO) [BR:
salp00001
]
09100 Metabolism
09105 Amino acid metabolism
00270 Cysteine and methionine metabolism
111968105
09106 Metabolism of other amino acids
00480 Glutathione metabolism
111968105
09140 Cellular Processes
09143 Cell growth and death
04216 Ferroptosis
111968105
Enzymes [BR:
salp01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.2 Acid-D-amino-acid ligases (peptide synthases)
6.3.2.2 glutamate---cysteine ligase
111968105
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Motif
Pfam:
GCS
GCS2
HasA
Motif
Other DBs
NCBI-GeneID:
111968105
NCBI-ProteinID:
XP_023849427
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Position
LG8:51662956..51670866
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AA seq
630 aa
AA seq
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MGLLSKGSPLNWEETKKYADHVRKHGIVQFLNIYNKVKERQKDVLLWGDEVEYMLIEMDE
KNGKVRLVLNGGEVLETLQDKGEKTNPNHPTLWRPEYGSYMIEGTPGQPYGGTMSEFNTV
EDNMGKRRREASSVLNKNETLATITSFPRLGCPGFTQPEYKPTPVEKGVSKSLFFPDEAI
NRHPRFSTLTRNIRHRRGEKVVINVPIFKDKCTPSPFVEKFPEDDGEAARAALPDHIYMD
AMGFGMGNCCLQVTFQACSIEEARYLYDQLATFCPIMMALSAASPFYRGYVSDIDCRWGV
ISASVDDRTGEERGLEPLKTNKFRILKSRYDSIDSYLSSCGDRYNDIDLTIEEEINKQLL
DAGIDKLLAQHIAHLFIRDPLSLFEEKIYLDDENESDHFENLQSTNWQTMRFKPPPPNSD
IGWRVEFRPMEVQLTDFENSAFVVFIVLLTRVILSYKLDFLIPLSKVDENMKVAQKRNAV
QEGMFYFRKDIYKGCNPALDSSSSAAQNGLDSEGDNEYTLMSIDTIINGKEGIFQGLIPI
LNXYLENMEVDVDTRCTILNYLKLIKRRASGELMTMAKWMREFVDKHPQYKQDSVITDRI
NYDLLRKCDSITKGEERCPELIGDPVNRGK
NT seq
1893 nt
NT seq
+upstream
nt +downstream
nt
atgggcttgctgtcaaaagggtcaccgctcaactgggaagaaaccaaaaaatatgcagac
catgttaggaaacatggcatcgttcagtttctcaacatctataacaaggtgaaagaacga
cagaaagatgtcttattatggggcgatgaggtggaatacatgttgattgaaatggatgag
aaaaatggaaaggttcgrcttgttctcaatggtggagaggttttggaaacccttcaagac
aaaggagaaaagaccaaccccaaccatcctaccctttggaggccagagtatggcagctac
atgatcgaagggactccygggcagccctacggtgggacgatgtcagagttcaacacagtg
gaggacaacatggggaagcgaaggcgagaggcctcatctgtgctgaataagaatgaaaca
cttgccaccatcacgtcattcccaaggttaggctgcccaggcttcacacagccagaatac
aagccaacacctgttgaaaagggagtgtcaaaatcactgttcttcccagatgaagccata
aacagacacccaagattcagcaccctgaccagaaacattcgtcacagaagaggagagaag
gtggtgatcaatgtacccatctttaaagacaaatgcaccccatctccatttgtggagaag
tttccggaagatgatggagaggccgccagggcagctctacctgatcacatctacatggat
gccatgggatttggaatgggcaactgctgtcttcaggtgacattccaagcctgcagcatt
gaagaggcgaggtacctttatgaccaactagcaacattctgccctataatgatggccctc
agtgctgcttcgccgttctacagaggctatgtgtcagacattgattgtcgctggggagtt
atttctgcstcggtagatgacaggaccggggaagagagggggctggagcctttgaaaacc
aacaaatttcgkatcttgaaatccagatatgattcaatcgacagctacctctccagctgt
ggcgataggtacaatgacatagatctgacaatagargaggagatcaacaaacaactgctg
gatgcagggattgacaaactgctggcccaacacatagcccatctcttcatccgggatccg
ctctcactatttgaagagaaaatttacttggatgatgaaaacgagtctgatcattttgag
aatctgcagtcaaccaactggcagacaatgaggttcaaacctcctcctccaaactcggac
atcggatggcgagttgagttccgtcccatggaggtgcaacttaccgattttgaaaactct
gcattcgttgttttcatcgtcctgctcaccagggttatactgtcctataaactggacttt
ctcatccccttgtcaaaggttgacgaaaacatgaaagttgcccagaaaagaaatgcagtc
caagagggcatgttttacttccggaaggacatctataaaggctgcaaccctgccctcgat
agctcctcytcggctgcccagaatggcttggacagtgagggtgacaatgagtacacactg
atgagcattgacacaatcatcaatggaaaggaaggaatttttcaagggttgataccaatc
ctcaactgrtacctagaaaacatggaggtggatgttgatacaagatgcaccatcctgaac
tacctgaagctcatcaagagacgtgcctctggtgaactgatgaccatggctaaatggatg
agggagtttgtggacaagcacccccaatacaagcaagacagtgtcataactgacagaatc
aactacgacctactccgcaagtgtgacagcatcacaaaaggagaggagcgatgcccagaa
cttattggtgacccagtcaatcggggcaaatga
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