Salvelinus sp. IW2-2015 (Arctic char): 111975375
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Entry
111975375 CDS
T05762
Symbol
pik3ca
Name
(RefSeq) phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform
KO
K00922
phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha/beta/delta [EC:
2.7.1.153
]
Organism
salp
Salvelinus sp. IW2-2015 (Arctic char)
Pathway
salp00562
Inositol phosphate metabolism
salp01100
Metabolic pathways
salp04012
ErbB signaling pathway
salp04068
FoxO signaling pathway
salp04070
Phosphatidylinositol signaling system
salp04081
Hormone signaling
salp04140
Autophagy - animal
salp04150
mTOR signaling pathway
salp04210
Apoptosis
salp04218
Cellular senescence
salp04370
VEGF signaling pathway
salp04510
Focal adhesion
salp04620
Toll-like receptor signaling pathway
salp04625
C-type lectin receptor signaling pathway
salp04810
Regulation of actin cytoskeleton
salp04910
Insulin signaling pathway
salp04914
Progesterone-mediated oocyte maturation
salp05100
Bacterial invasion of epithelial cells
salp05132
Salmonella infection
salp05168
Herpes simplex virus 1 infection
Brite
KEGG Orthology (KO) [BR:
salp00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00562 Inositol phosphate metabolism
111975375 (pik3ca)
09130 Environmental Information Processing
09132 Signal transduction
04012 ErbB signaling pathway
111975375 (pik3ca)
04370 VEGF signaling pathway
111975375 (pik3ca)
04068 FoxO signaling pathway
111975375 (pik3ca)
04070 Phosphatidylinositol signaling system
111975375 (pik3ca)
04150 mTOR signaling pathway
111975375 (pik3ca)
09133 Signaling molecules and interaction
04081 Hormone signaling
111975375 (pik3ca)
09140 Cellular Processes
09141 Transport and catabolism
04140 Autophagy - animal
111975375 (pik3ca)
09143 Cell growth and death
04210 Apoptosis
111975375 (pik3ca)
04218 Cellular senescence
111975375 (pik3ca)
09144 Cellular community - eukaryotes
04510 Focal adhesion
111975375 (pik3ca)
09142 Cell motility
04810 Regulation of actin cytoskeleton
111975375 (pik3ca)
09150 Organismal Systems
09151 Immune system
04620 Toll-like receptor signaling pathway
111975375 (pik3ca)
04625 C-type lectin receptor signaling pathway
111975375 (pik3ca)
09152 Endocrine system
04910 Insulin signaling pathway
111975375 (pik3ca)
04914 Progesterone-mediated oocyte maturation
111975375 (pik3ca)
09160 Human Diseases
09172 Infectious disease: viral
05168 Herpes simplex virus 1 infection
111975375 (pik3ca)
09171 Infectious disease: bacterial
05132 Salmonella infection
111975375 (pik3ca)
05100 Bacterial invasion of epithelial cells
111975375 (pik3ca)
09180 Brite Hierarchies
09182 Protein families: genetic information processing
04131 Membrane trafficking [BR:
salp04131
]
111975375 (pik3ca)
Enzymes [BR:
salp01000
]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.1 Phosphotransferases with an alcohol group as acceptor
2.7.1.153 phosphatidylinositol-4,5-bisphosphate 3-kinase
111975375 (pik3ca)
Membrane trafficking [BR:
salp04131
]
Endocytosis
Rab GTPases and associated proteins
Rab associated proteins
111975375 (pik3ca)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
PI3Ka
PI3_PI4_kinase
PI3K_C2
PI3K_rbd
PI3K_p85B
DUF2321
ABC1
Ribosomal_S15
C2
Motif
Other DBs
NCBI-GeneID:
111975375
NCBI-ProteinID:
XP_023859397
LinkDB
All DBs
Position
LG16:22351102..22367275
Genome browser
AA seq
1068 aa
AA seq
DB search
MPPRPSSGELWGIHLMPPRIFVDCLLPNGMILTLECLREATLITIKHEVFKEARKYPLHH
LLQEETSYIFVSVTQEAEREEFYDETRRLCDLRLFQPFLKVIEPVGNREEKILNREIGFA
IGMPVCEFDLVKDPEVQDFRRNILNVCKDSVELRDANGPHSRALYVYPPNVESTQELPKH
IHGKLDKGQIIVVIWVIVSPNNDKQKYTLKINHDCVPEQVIAEAIRKKTRSMLLSPEQLK
MCVQEYQGKYILKVCGCDEYLLEKFPLSQYKYVRSCIMLGRMPNLMLMAKDSLYSQLPMD
NFTMPSYARRISTATPYMNGESSTKSLWTINGTLRIRVLCATYVNVNIRDIDKIYVRTGI
YHGGEQMCDNVNTQRVPCSNPRWNEWLTYDMYIPDIPRAARLCLSICSVKGRKGAKEEHC
PLAWGNVNLFDYTHTLVSGKMALNLWPVPHGLEDLLNPIGVTGSNPNKETPCLELEFDYF
SSPVKFPDMTTVEGHANWTISRELGFNYCQSGQSNRVARDHALTDSDNEQLRQVCNRDPL
SEITEQEKDFLWRHRHYCVNIPEILPKILLAVKWNSRDEVAQMYCLLKDWPAIKPEQAME
LLDCNYPDPMIRDFAVRCLEKYLTDDKLSQYLIQLVQVLKYEQYLDNPLVRFLLKKALTN
QRIGHFFFWHLKSEMHNKTVSQRFGLLLESYCRACGMYLKHLSRQVEAMEKLINLTDILK
QEKKDETQKVQMKFLVEQMRRPDYMDALQNFTSPLNPAHQLGNIRLEECRIMSSAKRPLW
LNWENPDIMSELLFQNNEIIFKNGDDLRQDMLTLQIIRIMENIWQNQGLDLRMLPYGCMS
LGDCVGLIEVVRSSHTIMQIQCKGGLKGALQFNSSTLHQWLKDKNKGEMYDLAVDLFTRS
CAGYCVATFILGIGDRHNSNIMVKDDGQLFHIDFGHFLDHKKKKFGYKRERVPFVLTQDF
LIVISKGTQECTKTREFERFQEMCYKAYLAIRQHANLFINLFSMMLGSGMPELQSFDDIA
YIRKTLALDKTEQEALDYFMKQMNDAHHGGWTTKMDWIFHTIRQHALN
NT seq
3207 nt
NT seq
+upstream
nt +downstream
nt
atgcctcctaggccttcttctggtgaattatggggcatccatttgatgcccccccggatc
tttgtggactgcttgttgccaaacgggatgatcctgaccctcgagtgcctccgtgaggct
acgctcatcaccatcaaacatgaagtgttcaaggaggccaggaagtaccccctgcatcac
ctactacaggaggagacctcttacatatttgtcagtgttacgcaggaggcagagcgagag
gagttctacgatgaaactaggagactatgtgatctcaggctctttcagccttttctgaag
gtcatcgaaccggttggtaaccgagaggagaaaattctgaacagagaaattggattcgca
attggtatgcctgtttgcgagtttgacttagtaaaggaccctgaggtgcaggacttcagg
aggaatattcttaacgtctgtaaggattcagtagaactccgagacgccaatggaccccat
agtcgggctttatatgtctaccctcccaatgttgaatcgacacaagaacttccaaagcac
atccatggcaaactggacaaaggtcaaatcattgtagtgatctgggtgattgtctcaccc
aacaatgacaagcagaaatacaccctgaagatcaaccatgattgtgtgccagaacaggtg
atagctgaggccatcaggaagaagaccaggagcatgctgttgtcccctgaacaactcaag
atgtgtgtgcaggagtaccagggcaagtacatcctcaaggtgtgcggctgtgacgagtac
ctcctggagaaattccccctgagtcaatataagtatgtgaggagttgcatcatgcttggc
aggatgcccaacctcatgctgatggcgaaggatagcctttattctcagttacccatggac
aacttcaccatgccctcgtacgcccggcgcatctccaccgccaccccgtacatgaacgga
gagtcctccaccaagtctctgtggaccatcaacggaaccctgcggatacgagtgctctgt
gccacatatgtcaatgtgaacattcgggatatagataagatttatgtgcgaaccggcatc
taccatggaggggagcagatgtgtgacaatgtgaacacgcagcgtgtgccatgctctaat
cccaggtggaacgagtggctgacctacgacatgtacattcccgacatcccccgggcggcc
cgcctctgtctctccatctgctctgtgaaaggcaggaaaggggcgaaggaggagcactgt
ccactggcgtgggggaacgtcaacctgtttgactacactcacaccctggtctctggtaaa
atggctctgaacctgtggcctgtaccccacggcctggaggacctactcaaccccatcgga
gtcacaggctccaaccccaacaaggaaactccttgtctagagctggagtttgactacttc
agcagtcctgtcaagttcccagacatgaccaccgtggagggacatgctaactggaccata
tccagggagctaggtttcaactactgccagtcaggccagagtaacagagtggcgcgagac
catgccttaacggacagtgataacgagcagctgagacaggtgtgcaaccgagaccccctg
tctgagatcacagagcaggagaaggacttcctctggaggcacaggcactactgtgtaaat
atacctgaaatcctgcccaagatcctgctggctgtgaagtggaactccagagatgaagta
gcacagatgtattgccttctgaaggattggccagcaataaaaccagagcaagccatggag
ctgctggattgtaactatccagacccaatgatccgtgactttgctgttcggtgccttgag
aagtacttgaccgacgataaactctctcagtacctcattcagttggtccaggttctgaaa
tatgagcagtaccttgataacccactggtacgatttctactgaaaaaggccttgactaac
caaaggataggacacttctttttctggcacttaaagtccgagatgcacaataagacggtg
agtcagcggttcggcctgctgctggagtcctactgccgggcgtgtggcatgtacctgaag
cacctgagcagacaagtggaggccatggagaaactcatcaacctcaccgacattctcaaa
caggagaagaaggacgagactcagaaagtgcagatgaagtttctggtggagcagatgagg
aggccagactacatggacgccctgcagaatttcacctcccccctcaaccctgcacaccag
ctgggaaacatacggcttgaggagtgcagaatcatgtcatctgccaaaagaccactgtgg
ctcaactgggaaaaccctgacatcatgtccgagctcctctttcagaacaatgagatcata
ttcaaaaacggagacgacctgcgacaggacatgctaacacttcagatcatcagaatcatg
gagaacatttggcagaaccagggtctagacctcaggatgttgccgtacggctgcatgtct
ttaggtgactgtgtggggctgatcgaggtggtgcggagctctcacaccatcatgcagatc
cagtgtaaaggtggcttgaagggggcgctacagttcaacagctcaacactacaccagtgg
ctcaaagacaagaacaagggagagatgtatgaccttgccgttgacttgtttacgcgatcc
tgtgctgggtattgcgtggcgaccttcatcctaggcatcggtgacagacacaacagtaac
ataatggtgaaggatgatgggcagctttttcacatagattttggccattttctggatcac
aagaaaaagaaatttggctacaagcgagagcgagttccgtttgtcctaactcaagacttc
ttgattgtgatcagcaaagggacccaggagtgcacgaagaccagagagtttgagagattt
caggagatgtgctataaggcctacttggccattcgtcagcatgccaacctcttcatcaac
ctgttctccatgatgctgggctccgggatgcccgagctgcagtccttcgatgacattgcc
tacatccgtaaaaccctggccctggacaagactgagcaggaggccctggactacttcatg
aagcaaatgaacgacgcccaccatggcggctggaccaccaagatggactggattttccac
accatccgccagcacgcgcttaactaa
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