Salvelinus sp. IW2-2015 (Arctic char): 111979597 Help Entry 111979597         CDS       T05762                                  Name (RefSeq) obscurin-like   KO K17531   obscurin-RhoGEF [EC:2.7.11.1] Organism salp  Salvelinus sp. IW2-2015 (Arctic char) Pathway salp04820   Cytoskeleton in muscle cells Brite KEGG Orthology (KO) [BR:salp00001]  09140 Cellular Processes   09142 Cell motility    04820 Cytoskeleton in muscle cells     111979597  09180 Brite Hierarchies   09181 Protein families: metabolism    01001 Protein kinases [BR:salp01001]     111979597   09182 Protein families: genetic information processing    04131 Membrane trafficking [BR:salp04131]     111979597 Enzymes [BR:salp01000]  2. Transferases   2.7  Transferring phosphorus-containing groups    2.7.11  Protein-serine/threonine kinases     2.7.11.1  non-specific serine/threonine protein kinase      111979597 Protein kinases [BR:salp01001]  Serine/threonine kinases: CAMK group   Trio family [OT]    111979597 Membrane trafficking [BR:salp04131]  Others   Rho GTPase associated proteins    Rho guanine nucleotide exchange factors (GEFs)     111979597 BRITE hierarchy SSDB OrthologParalogGene clusterGFIT Motif Pfam:  I-set Ig_3 ig Ig_2 V-set Ig_4 Ig_5 Izumo-Ig Ig_6 C1-set V-set_CD47 fn3 SOS1_NGEF_PH RhoGEF Ig_DSCAM-DSCAML_C Ig_CD22 PH SH3_2 DUF3237 CDC48_2 PapD_C IQ Motif Other DBs NCBI-GeneID:  111979597 NCBI-ProteinID:  XP_024003450 LinkDB All DBs Position LG19:complement(13100520..13119558) Genome browser AA seq 6003 aa AA seqDB search MDQNLFGGAPRFLTRPKAFAVCVGKDATLSCTIVGNPTLLITWEKEKLRLTSGGRFKTVD DGNVYRLTIYDLTLEDSGQYMCRAKNNVGEAYACVTLHVGLPQEMVERAPVFMVKPTSVR VGLGGDVVFHCRVAAYPESTFDWDKDGRYLAETNRIKVSSDGDSSSLRIQSVRSLDSGTY TCRAQNSVGRSNSAATLVIDTQDSRHLGQDKSTSLLSHMQKRKEGISIYRTAETRSSSHN STTTSSTATTTVTDGLSGLGLAHGSAALVSQLPKSVFTRTCTVTEGKHAKLSCFVTGHPK PHIIWRKDGGNIGEGRRHIMYEDQAENFILKILYCKQSDNGLYTCNASNMAGQTYSAVLV IVKEPKVPFRRKLQDVEVQEKMTAMLLCEVPVSASQASWFMEETRLEDSSKYCMEEEGTM RRLTIRNVTTNDDAVYICEMKEGSRTVAELTVLGNITKKLPRRTVVSGSDTVIFCVELEH PNSDAYWTRNGERLKPDTRISIACTLRQYTLTINHCQADDSGEVAFVAGDCKTSTRFSVA AARKHPPDPPIDVVVRNKTDSSITLHWSPPDSDRPVPIKGYMVERRKVGAQTWQRCNGME VSPFTEITIQNITEEASYQFRISAVNDYGQSQYMEVPGTFYLEPSAELKTGLMNSTAISG EEASLSVDLSAVCSGSWSINGRLLRSGADYLITRQKTTHTLTIRTVLMEMNGAVVKFVGG GSESTCILHVKAPAIRFTSKSAHTEVVTCSAQSSAQLTTEVSDYDAQVVWMKNGRELKMG KKYECISTDRKRTLMVHNVTEEDTGIYECVLNEDRMSLQLSLKDEAKFLNKPRGPMGVAP ALSGDLELNCEVSSASGVVVWRKDQTLVTEDQRTTIVSKGTQRRLVVKNVKKSDEGHYSC ETVEDKVTFQVKIKEAQQAVFSNKDAVQKEVKVTLSQKATLSCEVSDPKTEVKWYKDGKL LTSSETVSTETKGRSRLLIVDKIEKKDAGDYTCEARAEKLVFKIHVSETQQSAFYNKESV QKEVKATLSQQATLSCEVSDTKTEVKWYKDGKLLTSSKTVSMSVWYPDTSQLRVAFCERL TSLALCSVKWYKDGKLLTSSKTVSMETKGKTRQLVIEKAEKKDAGEYTCEVGTEKLVYKI QVAEAQAVFXNKESVQKEVKATLSQQATLSCEVSDTKTEVKWYKDGKLLTSSKTVSTETK GKTRQLVIEKVEKKDAGEYTCEVGTEKLVYKIQVAEAPQAAFTNKDSVQKEVKANLSQKA TLTCEVSDTKTEVKWYKDGKLLPSSKTVSMETKGKTRNLVIEKMEKKDGGEYTCEVGTEK LDFKIHVAGETQAAFYNKESVQKEVKATLSQKATLSCEVSDTKTEVKWYKDGKLLTSSKT VSMETKGKTRQLVIENVEKKDAGEYTCEVGAEKLAFKIQMADTQAAFTNKESVQKEVKAT LSQKATLSCEVSDTKTETKGKTRQLVIEKVEKKDAGEYTCEVGAEKLAFKIEVAESSAKF KKTAVKGACSVQASEKIVLTTELTSESASVKWFRDGVELKESSKYDMKREGHSRTLIVKS TEVKDSGTYSCHTADDKLEFKVQVKDSPLKFVVQLQPVATELGGTLTLTCEMNRALGDVL WRHNSCEIIPGGRFCVSTDGPKRVLTVTGMAKEDEGEYSCECKDDKTSAKVSTKAPRLVK LTSKLSNVAAVEGKEAIFKCSVTPADVKVKWFCNNVPITAGPKYKIEHGGTSHSLTVTSV SQDDAQEISIDAEGKTCSATLQVQLEPVMFKKKLENVMVVEEQKEVKLEVELSKPSKEVR WMKNSVVLQPGGNMEIRVDGAKQTLVFKSVTTADRGYYSCETLDDKTQAKLTVDVKKIEV VNGLLPEVKAHEKETVTLEVELSQADVEGSWTRDSVKLKAGSNCRITALGKKHALTLSQI KMEDAGTIAFQAEGVKTSAKLIVTEPVAMISKPMEDVKAPEKEKATLECEVSRTNAEVKW FKGDMELKPGKNFRILSQGRTRSLLIHKCSQEDEGTYVCQTSDDNTSAKLTVHARDIQIV KKLEDVEVMEKESASFFCEISHDEVDCQWFKGDTKLKVGDNIKMRQEGKIYVLLFKSVTP EDFAEIKFTAEKASSTAKLTVKELPVQFVKKLRDKLALYTHRGFLECQVSRASAKVKWYK NKKEIKPSKKHEISSEGIYRKLTINDVGSDDEDTYTCDAIDDKTSCKLLVEEQAISIVRE LSAVEVTEPFAAFFEVEINIDSVKPPKWTLNGVAVQESVDVEMDKEGSMHRLTFKKTKAS MTGPVQFMAGKSKSVAQLTVQERPLEVVEPIKDMTVKEKGSATLSCKFSAAPKEVSWFKG QTLLDASDKYNLKQDAVRAQLTIQKLTGEDTGEYRCLSCAAETKATLTVEVRKVEITKHL VDTEVDEDSDAVFTCEINYTDEEVQWLLNEKALFSNEVNTITHMGKMHTLTLKNLAPEDG GTIIFKVREIKEGVTLKVKEKRAVFLKSLDDVVGEVKGMITLACEVSKPRVSPTWRKDGT ILTTGSKYEVLHTGKSLGLIIKDVTKEDAGEYSCDLGTELSKSKVTVRDLSIGITKQLKS VEAMEGETCSFQCILSRESTDECSWTFNGQTVANGGRFQVSSTGRKYMLVIKDVTPADAG EVVFNIKNLNSKTTLAVEGKAQSVSRELQSISVVSGEDAVFTCEVTQTRATVQWAKDGKD IRKSEKYEISKEERVMKLTVHSVTVQDSGEYSCEVIGGATTKAKLEIKEPVHKFTKELKD SEVEEEGSVTLQCETAQPASKATWSKGGVELKAGGRYEMSQKETVLHLTIKQLEEKDGGT YTCDVGTATMTAMVTVKALPASFIQKLKNQQAKEGESVTLCSVFIQTWGQAQPVTFKHKL ESQEAEEGGSVTLHSKCTRGQWRLQLLCGDQKTTAGLKIKAQPVTFKHKLESQEAEEGGS VTLHCELSKPGVPGEWRKGTQVLKSGEKYQMKQKESVSELLISKVVPEDSGDYSCVCGDQ KTTASLKIKALPVIFKQDLQSQEVEEGGSVTLHCELSKPGVPVEWGKGTQVLQSGEKYQM KQKDCSVELQVCDLKPEDTGSYHCRAGDTESSAYLKVNALPVIFTKELQSQQAEEGGSVT LHCELSKPGLPVEWRKXEVGLCPCAKYEILQEGHSARLVIQNLDPEDSGSYTCDSGDRKT TAHLAVKALPVYFKTRLQNLEWDAGEIAILRCEITKPGASVVWSRGDRVLESNNKYQLKQ EGAIVKLIIYSLQGADSGEYICDTGYQKTSSMLTVQDVEVTIVKVLNSCSVHEGEDVHFE CHLSHVDAKEVQWKLADVPLQNNEMNLIRAQGKVHSLTLRGVTQADSGTVTFTVGHHTST ASLTVRGAPVVFKKELESQEAVEGGSVSLTCEISADGKVTWRRGSVLLTQGEKYSMEHTG STYILMVHKLKVEDAGEYTCDTGXKQSTATLIVKESVRITRELHDITVTTGQNAVFACEL SQEGVTNGEWWLGDNLLQNNDLNQMTCQGRVHRLTLQMVTPDESGDVAFVVGEEKTVACL LVEEKPKALILEKPHDTVALEGETVTLSCTVSDPTATVTWSRNDVAIKAGLKYDLRKNGA LLQLRIHNLEMEDSGTYCCDTGDAQCTVTLTVEGAPAFFQKELKNQEAQEGDDITLHCEL SKAGTHVEWRKGGMVLQAGKKYEMRQEGCVQELHIRNLEPEDNGYYTCDAGDQLTTASVA VQAKPIEILQGLENMDTIDGGEALFECSISRCEIKDSCWLIDGKPVKDSPTTEIVSFESG RRHLLLLKDLHVGDNCKVTFQAGTAATSALLNVKGWQLDVVSGLEDKVAVVGEKVEFSCI LTEPVPKAEVAWYSNGAELKNDNTWAMQADGCSYHLVLRQAPAMPPQEITFAARDAISMA KLTVITVPDPPEDPELVSKHKQGVTLSWFTPLSDGGSPILGYRVEMRLADSALWLPCHAE PVCNTEFSVDNLIPGSGYRFRVAAINRAGTGEPVQLPQTVQLEAPITVTQQLACPDLQEG KMARVECQLSAEGSSVTWLRDNKELEFGVKYQVTIEGKTQVLLIKDFESADQGVYTCVAS DEAESSINLNLPTGEMGVSLEGAQPSLPPEAASEGDVHALWEALAKKRRMSREPTLDSIS ELPDEEDKEPKTSKEPVKEKKAPEKVNEKEKVVEPVIIAKKKELDTNLHTSSEDESRVPT LVSYLKKSSKSSLSASDQTESISTEKFYAQTSVQQTTVLQTSSSGQKITAQTTEITECGS EEIEEKGLLDAAVKIQAAFKGYKSCKDMCPVFKDVFKDQTKEPNGTIHLECVVEGKPDKV RWLKDGEPLVDSKHHHIDIYNDGTCSLVITAVTTKDTGIYTCEVTNKFGVTIHSGKVTVG SAREASGRRPLTMGYSADSEAESSSAESEMDESLRQASKRLRRLLRTRLPATSEEESFVS CDDEAVLQAPEPKSYREDERYLYIRFDTRSEAQVASLHFQEMFTAQGMPVETTIQEAGPL KVELRIMKMGYTQDGSATPTQEKQLPAFMTGAPAAPVFLTELQSQDVPDGYPVSFDCVVI GKPTPSVRWFKDGKLLEENDHYMINEDHEGCHQLIITTVLPSDMGVYRCMAENTSGIAAT KAELRVDMSCSSDYDTAADATETGSYISAKGYMSRETEAFESVAEDEQMPQVLDELHDVH VSPGSPIAKMQLKVKGFPXPRVYWFKDGITLRSSDRILLLDKRDVHSLEVLEVKREDTGE YSAYISNAAGSAYSSARILVLGPGELPPVEKHDPKVPLVPPRFLEKFSNRKVKQGASVTM SVRVEGSPTPMVTWLKEESAEDVLWIKPDTKGYKVARSGRQHSLILMDAGSEHAGTYTCI ATNRAGQSICTAHFEVEDAPRPKEETKXPLGITVSPPEENAGRKMPYLGEVGTEEFLMKL TSQITEMVSAKISQDSAQNHQVLQWMKSWPKASTSLRVPGGDSDDETKTPSASPHHGRSR PSSILADSSSESDDPDARGEMFDIYVATADYNPTIPNKETISLKEGQYVEVLDSAHPLKW LVRTKPTKTTPSRQGWVSPAYLDKKLKLSADAGDVPETGGEEVSEGEYKRRLLQLIQDMI NSEAEFVKEMDFFTSHHVKHVESPDAPSDITSQKEAIFRNINEIKAFHSEFMFPKLRECD TDDDVAMRFLRSGEGFEKYLQYLVGQQKAEAAISDKTVHHFFKKYTDKQQASADPAEGPV LSINAYLQKPLDRIQKYKASLKELIRNKARNGQNCCLLEEAYAMVSSLPQRSENTHHVSM IENYPATLDVLGEPIRQGPFMMWEGAPGVRSSSRGHRRHAFLFKNYVIICKSKRDSNTDT QGYVFKNMMKLNNIDVNETVEGDDRAFEIWHEREDSVRKYTLQARTVIIKNSWLRDLRDL QQRYTMPGWSMPDFDELLADCTAELGQTVKLACKVTGIPKPVVTWYKDGHAVEADPHHII IEDPDGSCTLILDNMTADDSGQYMGFATSTAGNASTLGKITVQVPPRFVNKMRNAVFTVG EDAQFSCTIQSAPSPKIRWFKEGRLLTDQEKYQTYSESRSGVLVLVIKGTTERDLGHYEC ELSNRLGSARCAADLCLPSAVTRRGEQAITIEVTEQETKIPKKTIIIEETITTVVKNTRM KRRGLSQSGFNRSQTSTPDLPTTPTARQRRQASANRKTTIPTLYVTDPEGGAGARAAENK WVEVEEIIEYKVNKSPRPSRRGVSPAGSERAHTPSSTRPQRSANPNANNNNNLVELQNHS ELQGAQPLYWDDEEEEDVDVAVDGSEVXPGISGDAYEVSSLLIPNDHEHEEDEAWLEEQQ EAFITEPDDDDNTPRKLEPKILTQGGRVLTLEDLEDYVPREGETYGSSNTRSSPPERPCE ISVLQREIGGSAVGQPVLLNVGRPVVMPRESPRPGFFSRFRDHLSGSMFSPAGPHHNYHP SGGQSRREIPIQVSHAKLEVKPLYCSEVQRVEGXQQSYKTKVYTSVGKPVTLQISKNNPY QNQ NT seq 18012 nt NT seq  +upstreamnt  +downstreamnt atggaccagaacctgtttggaggggcccccagattcctcacgcggcccaaagcgtttgca gtgtgcgtgggcaaggatgccactctaagctgcaccatcgtgggcaaccccaccctattg attacctgggaaaaggagaagctacgtctgacctctgggggccgcttcaagacggtggat gatggtaatgtctaccgcctcaccatctacgatctaaccctggaagacagcggccagtac atgtgccgggccaaaaacaacgtcggggaggcatacgcatgtgtaacccttcatgtaggc cttccacaggagatggtggagagggcccccgtcttcatggtcaagcctacctctgtacgc gttggcctggggggcgatgtggtcttccactgccgggttgctgcttacccagagtctaca tttgactgggataaggacgggcgttacctagccgagacaaaccgcatcaaggtgtcctcg gacggcgacagcagctccctgaggatccagagcgtgcgcagcctagacagcggcacgtat acctgccgcgcccagaactcagtgggccgctcgaactctgccgccaccttggtcatagac acccaggactcccgtcacctgggccaggacaagagcacctccctcctctcccacatgcag aagcgtaaagaagggatctccatctaccgcacagcagagacccgcagctcctctcacaac tccaccaccacctcttccacggccaccactacggtcacagacgggctgagcggtctgggt ctggcccacggcagcgcagcactggtcagccagctacccaaaagcgtctttacccgcacc tgcacggtgactgagggcaagcatgccaagctcagctgcttcgtgacgggtcaccccaag cctcatatcatctggaggaaggatggggggaacatcggcgagggacgaaggcacatcatg tatgaggaccaggccgagaatttcatcctcaagatcctgtactgtaagcagagcgacaat ggcctgtacacctgtaatgcctccaatatggctggacaaacctacagcgctgtgctggtg attgttaaagagcccaaggtgccgttcaggaggaagctgcaggatgtggaggtccaggag aagatgacggccatgctgctgtgtgaggtgcccgtttcggctagccaggccagctggttc atggaggagacacgtctggaggacagctccaagtactgcatggaagaggaggggaccatg cgtcgcctcaccatccgcaatgtcaccactaatgatgatgccgtctacatctgcgagatg aaggaggggagccgcaccgtagccgagctcactgtgctggggaacatcactaagaagctt cccaggaggactgtagtgtcggggagtgatacagtgatcttctgcgttgagctggagcac cccaattctgacgcctactggacacgcaacggcgagcgtctgaagccggacacacggata tccattgcctgcaccctcagacagtacacgctaaccatcaaccactgccaggccgacgac tcaggagaggtggcctttgtggctggagactgcaagacctccacacgattctctgtcgcg gctgccagaaagcaccctccagatccccctatcgacgtggtggtgcgtaacaagaccgac tcgtccatcaccctccactggtcccccccagacagtgaccgccccgtgcccatcaaaggg tacatggtagagaggaggaaggtgggtgcccagacctggcagaggtgcaatggcatggag gtcagcccctttactgagatcacgatccagaatatcacagaggaggccagctaccagttc cgcatctccgcagtcaacgactacggccagagccaatacatggaggtgcctgggaccttc tacctcgagccctctgcagagctgaagacaggcctgatgaacagcacagccatctcaggc gaggaggcctccctctccgtggacctgtctgccgtgtgctctggctcctggtctatcaac ggccgcctcctgcggagtggggctgactacctcatcacacgccaaaagaccacacatacg ctgacgatccgaactgtcttgatggagatgaatggagcagtggtcaaatttgtgggcggt ggctccgagagcacttgtatactccacgtgaaggctccagctatccggttcaccagtaag tccgctcacactgaggtggtgacctgcagcgcccagtcctccgcccagctgaccacagag gtgtccgattatgatgctcaggtggtctggatgaagaatggacgggagctgaagatgggc aagaagtatgagtgcataagcaccgaccgcaagaggaccctgatggtgcacaacgtcacc gaagaggacacgggaatctatgagtgtgtcttaaatgaagaccgaatgtccctgcagctt tctctaaaagatgaagccaagttcctgaacaagcccaggggtcccatgggggtggcgcct gccctcagcggggaccttgagttgaactgtgaggtgtcgtctgcaagcggggtggtggtg tggaggaaggatcagacattggtcactgaggaccaaagaaccaccatcgtctccaaaggg acacagaggagactggtcgtcaagaatgtcaagaagagtgacgagggacactactcctgc gagacagtcgaggacaaagtcacattccaggtcaagataaaagaagcccaacaggctgtc ttctccaacaaggacgctgtacagaaggaggtgaaagttactctctcccagaaagccact ctgagctgtgaggtgtctgaccccaagacagaggtgaaatggtacaaggatggcaagctg ctgacttccagtgagacagtctccacggagacaaagggcaggagtcgtctgttgatagta gacaaaattgagaagaaggatgctggagattacacctgtgaggctagagcagagaagctg gtctttaaaatacatgtttcagaaacccaacagtctgccttctacaacaaggagtctgta cagaaggaggtgaaagctactctctcacagcaagccactctgagctgtgaggtgtctgat accaagacagaggtgaaatggtacaaggatggcaagctgctgacttccagtaagaccgtc tccatgtctgtctggtatccagacacctcacagctcagagtggctttctgtgagagactg acgagtcttgccctttgctcggtgaaatggtacaaggatggcaagctgctgacttccagt aagaccgtctccatggagacaaagggcaagactcgtcagctggtgatagagaaggcggag aagaaggatgctggagagtacacctgtgaggttggaacggagaaactggtctataagatt caggtggcagaagcccaggctgtcttcwmcaacaaggagtctgtacagaaggaggtgaaa gctactctctcacagcaagccactctgagctgtgaggtgtccgacaccaagacagaggtg aaatggtacaaggacggcaagctgctgacttccagtaagaccgtctccacggagacaaag ggcaagactcgtcagctggtgatagagaaggtggagaagaaggatgctggagagtacacc tgtgaggttggaacggagaaactggtctataagattcaggtggcagaagcaccacaggct gcattcaccaacaaggactctgtacagaaggaggtgaaagctaatctctcacagaaagcc actctgacctgtgaggtgtccgacaccaagacagaggtgaaatggtacaaggacggcaag ctgctgccttccagtaagaccgtctccatggagacaaagggcaagactcgtaatctagtg atagaaaagatggagaagaaggatggtggagagtacacctgtgaggtgggaacagaaaag ctggacttcaagatacacgtggcaggagaaactcaggctgccttctacaacaaggagtct gtacaaaaagaggtgaaagctactctctcccagaaagccactctgagctgtgaggtgtcc gacaccaagacagaggtgaaatggtacaaggacggcaagctactgacttccagtaagacc gtctccatggagacaaagggcaagactcgtcagctggtgatagaaaatgtggagaagaag gatgctggagagtacacctgtgaggttggagcagagaaactagccttcaagattcagatg gcagacactcaagcagccttcaccaacaaggagtctgtacagaaggaggtgaaagctact ctctcccagaaagccactctgagctgtgaggtgtctgataccaagacagagacaaagggc aagactcgtcagctggtgatagagaaggtggagaagaaggatgctggagagtacacctgt gaggttggagcggagaagttggccttcaagatagaggtggcagaatcctctgccaaattt aaaaaaactgcagtgaagggtgcatgcagtgttcaagcaagtgagaagattgttttgacc actgagttgacttcggagagtgccagtgttaagtggttcagggacggtgtggagttgaag gagagctctaagtatgacatgaagagagagggacattctcgtaccctgattgtgaagtcc actgaagtcaaagacagtggcacctactcatgccacactgctgacgacaagcttgagttc aaagttcaagtcaaggattcaccgctgaagtttgtggtgcagttgcagcctgtagccaca gagctgggtggtacactgaccctgacctgtgaaatgaaccgagccttaggggacgtgctc tggcgccacaacagctgtgagatcatacccggcggcaggttctgtgtcagcactgatggt cccaagcgggtccttactgtgacaggaatggcgaaagaggatgagggagaatacagctgt gaatgcaaagatgataagacctctgccaaggtctccaccaaagcacccagactggtgaag ctgacttccaagctgagcaacgtcgctgctgtggaggggaaggaggccatcttcaagtgt agtgtcaccccagctgacgtcaaagtgaaatggttctgcaacaacgtgcccatcactgct gggcctaaatataagattgagcatgggggcaccagccattccctcaccgtcacctcagtg agtcaggatgatgctcaagagatcagcattgatgcagagggcaaaacctgcagtgctacc ctccaagtgcaactggagccggtgatgttcaagaagaagctggagaatgtgatggtggtg gaggaacagaaggaggtgaagctggaggtagagctgagtaaaccctctaaagaggtcagg tggatgaagaacagcgtggtgctacagcctggaggcaacatggagatcagggtggacgga gccaagcagaccctggtctttaagagtgtgactacggccgatcgtggctactactcctgt gagaccctggacgacaagacccaggccaagctcacagtggatgtgaaaaagattgaggtg gtgaacggcctgctgccggaggtcaaggcccatgagaaggagacggtgaccctagaggtg gagctcagccaggctgacgtggagggctcctggaccagggacagcgtcaagctcaaggca gggtccaactgccgcatcacggccctgggaaagaagcacgccctcacactatcccaaatc aagatggaggatgcaggaacaattgccttccaagcagagggggtcaaaacttctgccaaa ctcattgttacagaacctgtggctatgatctctaaacccatggaggatgtcaaagcccca gagaaggagaaggcaacgcttgagtgtgaggtgtccagaactaatgctgaggtcaagtgg ttcaagggtgacatggaactgaaaccaggaaagaacttccgcatcctctcccaggggcgc acacgcagcctgctaatccacaaatgttcacaagaggatgagggcacatacgtctgccaa acgtctgatgacaacacatcagctaaactcactgttcatgcccgagacattcaaatagtg aagaagcttgaggacgtggaggtgatggagaaggagagcgcttcgttcttctgtgagatc tctcacgatgaagtggactgccagtggttcaaaggcgacaccaaactcaaagtcggtgac aacatcaagatgagacaagagggtaaaatctatgtgctgctgtttaagtcggtgacccca gaagactttgctgagattaaattcacagctgaaaaggcctcttcaacagccaaactgaca gtgaaagagctccctgtccagtttgtgaagaagctcagggataagttagccttgtataca caccgtgggttcttggaatgccaagtgtcccgggccagcgccaaggtcaagtggtacaag aacaagaaggagatcaagcccagcaagaagcatgagatcagcagcgagggtatataccgc aaactcaccataaacgacgtgggctcggatgatgaggatacttacacctgtgacgccatt gatgacaagacatcctgtaaacttcttgtggaagagcaggccatcagcatcgtacgggag ctaagtgccgtggaagtgaccgagccctttgccgccttcttcgaggtggagatcaacatc gactcagtcaagccccccaagtggaccctgaatggtgtggccgtgcaggagagcgttgac gtggagatggataaggagggctccatgcaccgcctcacctttaagaagaccaaggcgtcc atgacaggacctgtccagttcatggctggcaagagcaagtctgtggcccagctcactgtc caagagcgccctcttgaggtggtagagcccattaaagatatgacagtcaaggagaagggc tcagccactctgagctgcaagttctccgccgcacccaaagaggtgagctggttcaaaggg caaaccctcctggatgcttccgacaagtacaacctgaaacaggacgctgtgagggctcag ctgaccatccagaagctgactggggaagacactggggagtaccgctgtctgtcgtgtgct gccgagaccaaagccactctcactgtagaggttcggaaagtggagatcaccaaacacttg gtggacacagaggtggatgaggacagtgatgcagtgttcacctgtgagatcaactacact gatgaggaggtgcaatggctactcaatgaaaaagcactcttctccaacgaggtcaacacc atcacacacatgggcaaaatgcacacgctcacactcaagaatctggcacctgaggatggg ggcaccatcatcttcaaggttagggaaatcaaggagggtgtgaccctaaaagtcaaagag aagcgtgcagtgttcctcaagtctctggatgatgtggtgggagaggtgaaaggtatgatc accctggcttgtgaggtctccaagcccagggtctcccccacctggaggaaagatggtacg atccttaccactggctctaagtatgaggtcctgcacaccggcaagtccctgggtctgatc atcaaggatgttaccaaggaagacgcaggggagtacagctgcgacctgggaactgagctt tccaagtcaaaggtcactgtgagagacctgagcataggtatcaccaagcagttgaagtcc gtggaggcgatggagggagagacatgtagctttcagtgtattctgtcacgggaaagcact gacgagtgttcctggaccttcaatggccagaccgtggctaacggaggacgcttccaggtc tccagtacaggtcgcaagtacatgctggttatcaaggatgtgacaccagccgatgctggt gaggtggtcttcaacatcaagaacctgaactccaagactaccttagctgttgaaggcaaa gctcaatctgtatcacgggagctgcagagcattagtgtagtctcaggggaggatgctgtg ttcacctgtgaggtcacacagaccagggccactgtccagtgggccaaagatgggaaggac atcaggaagagtgagaagtatgagatcagtaaagaggagagggtcatgaagttgaccgtc cacagtgtcactgttcaggactctggggaatatagttgtgaggttatcggaggtgcaact accaaggccaagctggagatcaaagagccagtccacaagtttaccaaggagcttaaggac agcgaggtggaggaggagggctcagtgaccctgcagtgtgagacagcccagcctgcctcc aaggccacctggtccaagggaggcgtggagctgaaggccgggggacgctatgagatgagt cagaaggagaccgtcctccacctcactatcaaacagctggaggagaaagacggcggcact tacacctgtgacgtgggcactgcgacgatgacggcaatggtgacagtcaaagccttgcct gccagctttatacaaaagctgaagaaccagcaggccaaggaaggggagagtgtcacgctc tgctctgtgtttatccaaacctggggccaagcccaacctgttacattcaaacacaaactg gagagccaggaggctgaggaggggggcagtgttaccctgcactcaaagtgtaccagagga cagtggagactacagctgttgtgtggagaccagaagactacagccggtctcaagataaag gcccaacctgttacattcaaacacaaactggagagccaggaggctgaggaggggggcagt gttaccctgcactgtgagctctctaaacctggagtccctggggaatggaggaagggaaca caggtgctgaagtctggagaaaagtaccagatgaagcagaaagaatctgtgagtgaactc ctgatcagcaaagtggtaccagaggacagtggagactacagctgtgtgtgtggagaccag aagactacagccagtctcaagataaaggctcttccagtcatattcaaacaagatctgcag agtcaggaggttgaagaggggggcagtgttaccctgcactgtgagctctctaaacctggg gtccctgtggaatgggggaagggaacacaggtcctgcagtctggagaaaagtaccagatg aagcagaaagattgcagtgtggaactccaagtctgtgatttgaaacctgaagacacggga agctaccactgcagggctggagacacagagagctcagcatacctgaaagtcaatgctctc ccagtcattttcactaaagagctgcagagccaacaggctgaagaggggggcagtgttacc ctgcactgtgagctttctaaacctgggctccctgtggaatggaggaaggyggaggtgggt ctttgcccctgtgccaagtatgaaatcctccaggaagggcacagcgctaggctagtcatc caaaacttagacccagaagactcaggcagctacacctgtgacagtggtgaccggaaaacc acagcacaccttgctgtgaaggccctgcccgtttacttcaaaactcgactacagaatcta gagtgggacgcaggtgagatcgccatcctccgctgtgagatcaccaagcctggggccagc gttgtctggagccggggcgacagggtcctggaatctaacaacaagtatcagctgaaacag gaaggggccattgtgaagcttatcatctatagcctacaaggggctgactctggggagtat atctgtgacacaggttaccagaagacctcctccatgctcactgtacaggacgtggaggtg accatagtgaaggtcttgaacagctgttcggtgcacgagggggaggatgtccactttgag tgccatctgtcccacgttgatgccaaggaggtccagtggaagcttgcggacgtccctctg cagaacaatgaaatgaacctgatccgtgcccagggcaaggtgcacagcctcaccctcagg ggggtcacccaggccgactcgggcacagtcaccttcaccgtgggtcaccatacctccacc gcaagcctgaccgtccgaggggcccctgtggtgttcaagaaggagctggagagccaggaa gcagtggagggaggcagtgtttccctgacctgtgagatcagtgctgatggcaaggtgacc tggagaaggggctctgtgctcctcacccagggggagaagtattccatggagcacacaggt tctacctacatcctgatggttcacaagttaaaggttgaagatgctggagagtacacctgc gataccgggmataagcagagcacagccaccctgatagtcaaagagtctgtacgcatcact cgggagctgcacgacatcacagtgaccaccgggcagaatgctgtctttgcgtgtgagttg tcccaggagggcgtgaccaacggagagtggtggctgggcgataacctcctccagaacaac gacctgaaccagatgacctgccagggccgggtacaccggctgacactgcagatggtcacc cccgatgaatcaggggacgtggcgtttgtggtgggcgaggagaagaccgtcgcttgccta ctggtggaagagaagcccaaagccttaatccttgagaagcctcacgatacagtggccttg gagggtgagacagtcaccctgtcctgcactgtctccgaccccacggcaaccgtcacctgg agcaggaatgatgtggctatcaaagcaggactcaagtacgacctgcggaagaatggagct ctcctgcagctgcgcatccacaacctggagatggaggactctggaacctactgctgcgat accggggatgcacagtgcaccgtcaccttgactgtggaaggtgccccggcattctttcag aaagagctgaagaaccaggaagcccaggagggtgatgatatcactctgcactgtgagctc tccaaggcgggcactcacgtggagtggaggaagggaggcatggtcctccaggctggtaag aagtacgagatgaggcaggagggctgcgttcaggagctccacattcgcaacctggagcca gaggacaacggctactacacctgtgatgctggagatcagctcaccacggcgtcagtggca gtgcaagccaaacccatagaaatcctccagggcctggagaacatggacaccatcgacggc ggcgaggccctgttcgagtgctcgatctctcgttgcgagatcaaagacagctgctggctc attgacggcaagccggtgaaggattcgccaaccactgagattgtgtccttcgagagtggc cgccgccacctgctgctgctaaaggatctgcacgtcggggacaactgcaaagtgaccttc caggctggcaccgcagcgacctccgccctgctcaacgtcaaaggctggcagctggatgtg gtgagcggtctggaggataaggtagctgtggtgggagagaaggtagagttcagctgcata ctgactgagcctgtgcctaaagcggaggtagcctggtactctaacggagccgagctaaag aatgataacacctgggccatgcaggctgacggttgctcctaccacctggtgctgagacag gccccagccatgccaccacaggagatcacctttgctgccagggatgccatttccatggcc aagctcactgtcatcaccgttccagaccccccggaggacccagagctggtcagtaagcat aaacagggggtgaccctgtcctggttcacacctctcagcgatggaggcagccccattttg ggttacagggtggagatgaggctggcggacagcgccctctggcttccgtgccatgcagag cctgtgtgtaacacagagttctctgtggataacctcatcccagggagcggctacaggttc agggtggcagckatcaacagagctgggactggagaacctgtccagctgcctcagaccgtt cagctggaggctccaatcacagttacccagcagttggcctgtccagacttgcaggagggt aagatggcccgtgtagagtgccagctctctgctgagggcagctcggtcacctggctcaga gacaacaaggagctggagtttggggtcaaataccaggtcaccatcgagggcaagacacaa gtgctyctgatcaaagactttgagtctgctgaccagggcgtgtacacctgtgtggcctca gacgaggcagaaagctccattaatctcaacctaccaacaggtgagatgggggttagtttg gagggggcccagcccagcctgcctcctgaggctgcctccgagggtgatgtccacgcgctg tgggaggccctggccaagaaacgccgcatgagccgagagcccaccctagactccatctct gagctgcctgatgaggaggacaaggagccgaaaacatccaaggagccagtcaaggagaag aaagccccagagaaggtgaacgaaaaggagaaggttgtggagcctgtcatcatcgcaaag aagaaggagttggataccaatctacacaccagctctgaggatgagtccagggttccaacg ctggtgtcctacctgaagaagagcagcaagtcctccctctctgcatccgaccagacagag tccatctcaactgagaagttctatgcacagacctcagtgcaacagaccacagtcctacag acctcatcttcgggacagaagatcacagcacagaccacagagatcactgagtgcggaagt gaggagattgaagaaaaggggctgctggatgctgctgtcaagatccaggctgcgttcaag ggctacaagtcctgcaaggacatgtgtccagtcttcaaggatgtcttcaaggaccagacc aaggagcccaatggcaccatccacctggagtgtgtggttgagggcaagcccgacaaggtg cgctggctgaaggacggcgagccccttgtggacagcaaacaccatcacatcgacatctac aacgatggcacctgctctctggtaatcaccgccgttaccaccaaggacacgggcatctac acatgtgaggtcaccaacaagttcggcgtgaccatccacagcggcaaggtgacagtaggc tcggcacgggaggcatctggaaggaggcccctgaccatgggctacagcgctgacagcgag gcggagagctcgtctgcagaaagcgagatggatgagtctttgaggcaggccagcaaacgg cttcgccgcctcctccgcacacgcctgccggccacgtcggaggaggagtcgtttgtcagc tgtgatgatgaggctgttctgcaggcccccgagcccaaatcgtaccgtgaggacgagcgc tacctctacatccgctttgacacgcggtctgaggcacaggtggcgtcgctgcactttcag gagatgttcacggcccaggggatgcctgtggagaccaccatccaggaggctggacctctc aaagtggagctgcgcatcatgaagatgggatacactcaagatggctctgcaacacccaca caggagaagcagctgcccgcgttcatgacaggagcccctgcggccccagtcttcctgacc gaactccagagccaggacgtgcctgacggttacccggtcagctttgactgcgtggtgatc ggaaagcctacacccagcgtgcgttggttcaaggacgggaagctcctggaggagaatgac cactacatgatcaacgaggaccacgagggctgccaccagctcatcatcaccaccgtgctg ccttctgacatgggcgtctaccgctgcatggccgagaacaccagtggcattgctgccact aaggctgagctcagggttgacatgtcttgcagttcagactacgatactgcagctgatgcc actgagacaggctcctacatcagcgccaagggctacatgtcaagggaaacggaagcgttt gagtctgtggcagaggatgagcagatgccacaagtactggatgaactccatgatgtgcac gtcagcccaggctcacccatcgctaagatgcagctgaaagtcaaaggtttccccycgccc agagtgtactggttcaaggacggtatcacgctgcgttcctcagacaggatcctgctgctg gacaagagagacgtccacagtctggaggtcctggaggtgaagagggaggatacaggagag tactctgcctacatcagcaacgctgctggatcagcatactcctctgctaggatactggtt ctgggtccaggagagctcccacctgtagaaaagcacgatcccaaggtgcctctggtgccg ccacggttcctggagaagtttagcaacaggaaggtgaaacagggagccagtgtcaccatg tcagtcagagtggaaggttctcccacccccatggtgacgtggctgaaagaggagtctgct gaggacgtgttgtggatcaagccagacactaagggctataaggtggccaggtctgggcgc caacacagcctcatcctcatggatgcgggttctgagcacgccggcacctacacctgcata gccaccaacagggccggccagtccatctgcactgcccactttgaggtagaggatgcgcca cgaccaaaggaagagaccaaaatscctctgggtattactgtcagccctccagaggagaat gctggcagaaaaatgccttatctaggtgaagttggaacagaggagtttcttatgaagctc acctctcagatcacagagatggtatctgccaagatcagccaagacagcgcacagaaccat caagtgctccagtggatgaaatcatggcccaaagcctccacctcactacgtgtcccggga ggcgatagcgacgatgagaccaaaacaccctccgcctcgccccatcacggccgctctcgc cccagctccattctcgcggactcctcctctgagtctgacgaccctgatgccaggggagag atgtttgacatctatgtggctacggctgactacaaccccaccatccccaacaaagagacc atttccctgaaggagggccagtatgttgaggttctggattcggcacatccactcaaatgg ctggtccggaccaaaccaaccaaaaccaccccatcccgccagggctgggtctcgcctgcc tacctggacaagaaactcaagctgtctgctgatgctggtgatgtcccagagacaggtgga gaagaggtctcagaaggagagtacaaaagaagactactccaactgatccaggacatgatc aacagcgaggcagagtttgtcaaagagatggacttcttcacctcccaccacgtcaagcat gtggagagccctgacgccccatctgacatcaccagccagaaggaggccatattcaggaac atcaacgagatcaaggccttccatagcgagttcatgttccctaagttgcgcgagtgcgac acagatgacgacgtggccatgcggttcctgaggagcggggagggctttgagaaatacctc cagtaccttgtaggccagcaaaaggcagaggccgctatcagtgacaagaccgtacaccac ttcttcaagaagtacacagacaaacagcaggccagtgccgaccctgctgaagggcctgta ttgagcattaatgcctacctacagaaacctctggacagaatccagaagtacaaggcctca ctcaaggagctgatcaggaacaaggccaggaacggtcagaactgctgcctgctggaggag gcctatgccatggtttcatcactgcctcagcgttcagagaacacacaccacgtctccatg atagagaactaccctgccactctggatgtattgggggagcccatcagacagggacccttc atgatgtgggagggtgcacctggggtcaggtcctcctccagagggcaccgtcgacacgcg ttcctcttcaaaaactatgtcatcatctgcaaatccaagagagactccaacacagacacc cagggctacgtctttaagaacatgatgaagctgaacaacatagacgtgaacgagacagtg gagggtgacgaccgggcctttgagatctggcacgagcgcgaggactctgtcaggaagtac acgcttcaggctcgcaccgtcatcatcaagaactcctggctgcgagacctcagggacctg cagcagcgctacaccatgcccggctggagtatgcctgactttgatgagcttctggctgac tgcacagcggagctgggacagacagtgaaactggcctgcaaggttactggaatacccaaa cctgtggtcacctggtacaaggatgggcatgcggtggaggccgaccctcaccacatcatc atcgaggaccctgacggttcctgcaccctgatcctggacaacatgacagctgatgactct ggacagtacatgggcttcgccactagcaccgcaggcaacgccagcaccctggggaagatc actgtccaagtgcctcctcgtttcgtgaacaagatgaggaatgctgtctttaccgttggt gaggatgctcagttctcctgcaccatccagagcgcccccagccccaagatcaggtggttc aaggagggtaggctgctgactgaccaggagaagtatcagacctacagtgagtcccgtagt ggagtactggttctagtcattaaaggcactacggagagagacctgggacattacgaatgt gagttgtctaatcgactgggcagtgctaggtgtgcagctgatctgtgccttccttctgct gtgactaggagaggagagcaggcgatcaccatcgaagtcaccgagcaggagactaaaata ccaaagaaaaccatcatcatagaggagaccataaccacggtggtgaagaacacccgcatg aagcgtcgtggcctgtctcaatctgggttcaaccgctcccaaacctccaccccagatctc cccaccacccccacggccaggcagaggaggcaggcttccgccaacaggaagaccaccatc cccaccctgtatgtcacggaccccgaggggggcgcaggggcccgggctgcggagaacaag tgggtggaggtagaggaaataattgagtacaaggtcaacaagtcgcccaggccctccagg agaggtgtctccccagccgggtcggagcgggcgcacaccccctcctccacccggccacag aggtccgcaaaccctaacgccaacaacaacaacaacctggtagaactgcagaaccactcc gagctgcagggggcacagcctctgtactgggacgatgaggaggaggaggatgttgacgtg gctgtggatgggtccgaggtcycccctggaatcagtggagatgcctacgaggtctcctcg cttctaattcctaacgaccatgaacacgaagaggatgaggcctggctagaggagcagcaa gaggctttcatcacagaaccggatgacgacgacaacacacccaggaagctggagcctaag atcctgacccagggcggtcgcgttctcaccctggaggacctggaggactacgtccccagg gagggggagacctacggctcctccaacacccgttcatcacctcccgagaggccctgcgag atctcagttctccagagggagattggcggctctgctgtgggccagccggtgctgctcaat gtagggaggcctgtggtgatgcctagggagagccccaggccgggcttcttcagccgcttt agagatcacctctcaggaagcatgttctccccggccggcccccaccacaactaccacccc agcggaggtcagtccaggagggagattcccatccaggtcagccacgccaagctagaggtc aagccgttgtactgctctgaggtgcagagagtggagggastgcagcagagctacaaaacc aaagtctacacgtcagtgggcaagccagtcactcttcagattagcaagaataacccgtat caaaaccaataa

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