Candidatus Syntrophocurvum alkaliphilum: SYNTR_0539
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Entry
SYNTR_0539 CDS
T06326
Name
(GenBank) UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase
KO
K01929
UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase [EC:
6.3.2.10
]
Organism
salq
Candidatus Syntrophocurvum alkaliphilum
Pathway
salq00300
Lysine biosynthesis
salq00550
Peptidoglycan biosynthesis
salq01100
Metabolic pathways
salq01502
Vancomycin resistance
Brite
KEGG Orthology (KO) [BR:
salq00001
]
09100 Metabolism
09105 Amino acid metabolism
00300 Lysine biosynthesis
SYNTR_0539
09107 Glycan biosynthesis and metabolism
00550 Peptidoglycan biosynthesis
SYNTR_0539
09160 Human Diseases
09175 Drug resistance: antimicrobial
01502 Vancomycin resistance
SYNTR_0539
Enzymes [BR:
salq01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.2 Acid-D-amino-acid ligases (peptide synthases)
6.3.2.10 UDP-N-acetylmuramoyl-tripeptide---D-alanyl-D-alanine ligase
SYNTR_0539
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Gene cluster
GFIT
Motif
Pfam:
Mur_ligase_M
Mur_ligase_C
Mur_ligase
Motif
Other DBs
NCBI-ProteinID:
QGT99132
UniProt:
A0A6I6DEK2
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All DBs
Position
542693..544090
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AA seq
465 aa
AA seq
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MKFGLQLINDSINPKLIRGNANLEYSGVSTDSRNIVSQTLFFALAGDKFDGHDFVNIALE
NGANGAVISKKIDISTKFIDDKTIILVEDTLQALQDLATGYRKTFSNTNFIAITGSVGKT
TTKELLADFFNTEYSTLKTKGNFNNEIGLPLSILDLESHHKVAVFELAMRAKGEIKNLSD
ILNPNYAIITNVEPVHLEPMGSFKNIASAKCELLENIGLDGYALINGDIDILVKTAQEYK
CTKYTFGYKENNDIQIVNVETNENGLYIRLRIIDFITNLFFPIPTEKLAYNIAASTGLAY
LLGVDINNIKEVLSKYKTTHGRLHTTQQNGVTIMDDTYNANPLSMIAAIETLKNIGGKNR
RIAVLGDMYELGHMEKTGHIKVGEAVVSNSIDELVAIGKNAKYIAEGAASNKMNNENINC
FSNKEEAFNWLKTNIKVGDYILFKASRGMGLETIIKDLKDFLTNK
NT seq
1398 nt
NT seq
+upstream
nt +downstream
nt
atgaaattcggattacaattaattaatgattctataaaccctaagttaataagaggaaat
gctaatttagaatattctggggtatctactgattcacgaaatattgtatctcaaacttta
ttttttgcattagctggagataaatttgatggacatgactttgttaatatagcattagaa
aatggagctaatggtgctgtaataagtaaaaaaatagatatttcgaccaaatttatagat
gataaaacaataattttagtagaggatacgttacaagcattacaagatttagcaacagga
tatagaaaaacatttagcaatacaaattttattgctattaccggtagtgttggaaagaca
actactaaagaactactggctgatttttttaatactgagtacagtactttaaaaaccaaa
ggaaactttaataatgagattggattgcctttaagtattttagatttagaaagtcatcat
aaagttgctgtttttgagttagcaatgagagcaaaaggagaaataaaaaatctttcagac
atattaaacccaaattatgctattattacaaatgttgaaccagttcacttagaacctatg
ggtagttttaaaaacattgctagtgcaaaatgcgaattattagaaaatatagggttagac
ggttatgctttaattaatggtgatatagatatattagtaaaaactgcacaagaatataaa
tgtacaaaatatacatttggttataaggaaaataacgatatacaaattgtaaatgttgag
actaatgaaaatggtttatatattaggttaagaataatagattttattactaatttattt
tttccaataccaactgaaaaactagcatataatatagcggcttcaacaggattagcttat
cttttaggggtagatattaataatataaaagaagttttatcaaagtataaaactacacat
ggaaggctacatacaacacaacaaaatggtgtaactataatggatgatacctataatgca
aatccattatccatgatagctgcaatagaaacactgaaaaatatcggtggtaaaaacagg
agaattgctgtattaggtgatatgtatgaattagggcacatggaaaaaactggtcacatc
aaagtgggtgaagcagttgtatctaattcaatagacgaacttgtagctattggcaaaaat
gctaaatatattgccgagggtgcagcaagtaataaaatgaataatgaaaatataaattgt
ttttcaaataaagaagaagcatttaattggttaaaaactaacattaaagtaggcgattat
atattatttaaggcttcaagaggaatgggattagaaaccataataaaagatttaaaggat
tttttaaccaataaataa
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