Streptomyces noursei NK660: DC74_2568
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Entry
DC74_2568 CDS
T03082
Name
(GenBank) UDP-N-acetylmuramoyl-tripeptide--D-alan yl-D-alanineligase
KO
K01929
UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase [EC:
6.3.2.10
]
Organism
salu
Streptomyces noursei NK660
Pathway
salu00300
Lysine biosynthesis
salu00550
Peptidoglycan biosynthesis
salu01100
Metabolic pathways
salu01502
Vancomycin resistance
Brite
KEGG Orthology (KO) [BR:
salu00001
]
09100 Metabolism
09105 Amino acid metabolism
00300 Lysine biosynthesis
DC74_2568
09107 Glycan biosynthesis and metabolism
00550 Peptidoglycan biosynthesis
DC74_2568
09160 Human Diseases
09175 Drug resistance: antimicrobial
01502 Vancomycin resistance
DC74_2568
Enzymes [BR:
salu01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.2 Acid-D-amino-acid ligases (peptide synthases)
6.3.2.10 UDP-N-acetylmuramoyl-tripeptide---D-alanyl-D-alanine ligase
DC74_2568
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Gene cluster
GFIT
Motif
Pfam:
Mur_ligase_M
Mur_ligase_C
Mur_ligase
AIRS
PhageMin_Tail
Motif
Other DBs
NCBI-ProteinID:
AIA03072
LinkDB
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Position
complement(2921628..2923070)
Genome browser
AA seq
480 aa
AA seq
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MISLSLAEIASIVGGQQHDIPDPDREVTGPVVSDSRAVRPGGLFVAFAGERVDGHEFAVG
AVEAGATAVLASRPVGVPAIVVDDVVAALGALARAVVDRLGTTVVGLTGSAGKTSTKDLI
AQLLQRHGPTVWPEGNLNNEIGLPLTALRADATTRHLVLEMGARGIGHIRYLAGLTPPRI
GVVLNVGTAHLGEFGGREQIAQAKGELVESLPAAEDGGVAVLNADDPYVRAMASRTKART
VLFGESPEAAVRAENVRLSGLGQPAFTLHTPSGCSDVTMRLYGEHHVSNALAAAAVAHEL
GMPVDEIATALSEAGTLSRWRMEVTERADGVTVVNDAYNANPESMRAALRALVAMGTAAR
AQGGRTWAVLGEMAELGEESLAEHDAVGRLVVRLNVSKLVAVGGREAAWLDMGAKNEGSW
GEESVHVSDARAAIDLLRRELRGGDVVLVKASRSVGLERVAAALLDGEIGSGVEGGAASR
NT seq
1443 nt
NT seq
+upstream
nt +downstream
nt
gtgatctccctgtccctcgccgagatcgcgagcatcgtcggcgggcagcagcacgacata
ccggacccggaccgcgaggtcaccgggccggtcgtgtcggactcccgggccgtccgcccg
ggtggcctgttcgttgcgttcgccggtgagcgcgtcgacggtcacgagttcgccgtcggc
gccgtcgaagccggtgcgacggccgttctcgcgtcccgtccggtcggcgtcccggcgatc
gtcgtcgacgacgtcgtcgcagctctcggcgcacttgcccgggccgtcgtggaccggttg
ggcaccaccgtcgtggggctgaccggctcggccggcaagaccagcaccaaggacctgatc
gcccagctgctccagcggcacgggccgacggtgtggccggaaggcaacctcaacaacgag
atcgggctgccgctcaccgcgctgcgcgccgacgccaccacccggcacctcgtcctggag
atgggcgcccgcggcatcggccacatccgctacctcgccgggctgaccccgccccggatc
ggggtggtcctcaacgtcggcaccgcgcacctcggcgagttcggcggccgcgagcagatc
gcccaggccaagggcgagctcgtcgagtcgctgcccgcggccgaggacggcggtgtggcg
gtgctcaacgcggacgacccgtacgtccgggccatggcgtcccgcacgaaggcccgcacc
gtcctcttcggcgagtccccggaggccgccgtccgtgccgagaatgtccggctcagcggc
ctcggacagcccgccttcacgcttcacacaccctccgggtgcagcgatgtgacgatgcgg
ctgtacggtgagcaccacgtgtcgaacgcgctcgccgcggccgccgtcgcccatgagttg
ggcatgcccgtagacgagatcgccaccgcgctctccgaagccggcacgctctcccgctgg
cggatggaggtcaccgagcgcgcggacggcgtgacggtcgtcaacgacgcctacaacgcg
aaccccgagtccatgcgagcggcgctgcgtgcgctggttgccatgggcaccgccgccagg
gcgcaggggggccggacgtgggcggtgctcggtgagatggccgagctgggcgaggagtca
ctcgccgaacacgacgcggtcggacggctggtcgtccggctcaacgtcagcaagctcgtg
gcggtcggcggcagggaagcggcctggctcgacatgggcgccaagaacgagggttcgtgg
ggtgaggagtcggtgcacgtgtccgacgcgcgggcggcgatcgacctgttgcgcagggag
ctgcgagggggagacgtcgtgctggtgaaggcgtccaggtcggtcggcctggagcgggtc
gccgcggcattgctggacggcgagatcggttccggtgttgagggcggggccgcgtcccga
tga
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