Streptomyces noursei NK660: DC74_4144
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Entry
DC74_4144 CDS
T03082
Name
(GenBank) putative branched-chain alpha keto acid dehydrogenase E1 alpha subunit
KO
K00166
2-oxoisovalerate dehydrogenase E1 component subunit alpha [EC:
1.2.4.4
]
Organism
salu
Streptomyces noursei NK660
Pathway
salu00280
Valine, leucine and isoleucine degradation
salu00640
Propanoate metabolism
salu00785
Lipoic acid metabolism
salu01100
Metabolic pathways
salu01110
Biosynthesis of secondary metabolites
salu01210
2-Oxocarboxylic acid metabolism
Module
salu_M00036
Leucine degradation, leucine => acetoacetate + acetyl-CoA
Brite
KEGG Orthology (KO) [BR:
salu00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00640 Propanoate metabolism
DC74_4144
09105 Amino acid metabolism
00280 Valine, leucine and isoleucine degradation
DC74_4144
09108 Metabolism of cofactors and vitamins
00785 Lipoic acid metabolism
DC74_4144
Enzymes [BR:
salu01000
]
1. Oxidoreductases
1.2 Acting on the aldehyde or oxo group of donors
1.2.4 With a disulfide as acceptor
1.2.4.4 3-methyl-2-oxobutanoate dehydrogenase (2-methylpropanoyl-transferring)
DC74_4144
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Motif
Pfam:
E1_dh
TPP_enzyme_C
DXP_synthase_N
Motif
Other DBs
NCBI-ProteinID:
AIA04626
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Position
complement(4717009..4718226)
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AA seq
405 aa
AA seq
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MTVEGTAERKTARGGSKRTTAKKTTPAKKATQSKAGNSAGPDQAEQDQLVQLLTPEGTRV
EHPDYTIDLSPEELRGLYRDMVLTRRFDAEATTLQRQGELGLWASLLGQEAAQIGSGRAL
RDDDYVFPTYREHGVAWCRGVDPTNLLGMFRGVNHGGWDPNSNNFHLYTIVIGSQTLHAT
GYAMGVQKDGADSAVIAYFGDGASSQGDVAESFTFSAVYNAPVVFFCQNNQWAISEPTEK
QTRVPLYQRAQGYGFPGVRVDGNDVLACLAVTKAALDRARTGQGPMLIEAFTYRMGAHTT
SDDPTRYRPDEETLAWEAKDPILRLRKYLEAEGLVDDAYLAAIDEESDVLGKRVRDVVRA
MPDPDHLAIFENVYADGHALVDEERAQFAAYQASFADADAAAEGN
NT seq
1218 nt
NT seq
+upstream
nt +downstream
nt
gtgaccgtggaaggcactgccgagcggaaaaccgcccgcggcggcagcaagcgcaccacc
gccaaaaagacgacgccggcgaagaaggcgacgcagtccaaggccgggaacagcgccggg
ccggaccaggcggagcaggaccagctcgtacaactgctgaccccggaagggacgcgggtc
gagcacccggactacacgatcgacctctctcccgaggaactgcgcggtctctaccgcgac
atggtgctgacccggcggttcgacgccgaggcgaccaccctccagcgccagggcgaactg
ggcctgtgggcctcgctgctgggccaggaagccgcgcagatcggttccggccgcgcgctg
cgcgacgacgactacgtctttcccacctaccgggagcacggcgtggcctggtgccgcggc
gtcgacccgacgaacctgctggggatgttccgcggcgtcaaccacggcggctgggacccc
aacagcaacaacttccacctctacaccatcgtcatcggatcgcagacgctgcacgcgacc
ggctacgcgatgggcgtgcagaaggacggcgcggattccgcggtcatcgcgtacttcggt
gacggcgcgtccagccagggcgacgtcgccgaatccttcaccttctccgcggtctacaac
gccccggtcgtcttcttctgccagaacaaccagtgggcgatttccgagcccaccgagaag
cagacccgcgtccccctctaccagcgcgcccaggggtacggattccccggcgtccgggtg
gacggcaacgacgtgctggcctgcctggcggtgaccaaggcggcgctggaccgcgcgcgc
accggccagggccccatgctgatcgaggcgttcacctaccgcatgggcgcccacaccacc
tccgacgacccgacgcggtaccgcccggacgaggagacgctggcctgggaggccaaggac
ccgatcctgcggctgcggaagtacctggaggccgagggcctcgtcgacgacgcctacctc
gccgcgatcgacgaggagagcgacgtcctgggcaagcgggtccgcgacgtcgtacgggcc
atgcccgacccggatcacctggcgatcttcgagaacgtctatgccgacgggcacgcgctc
gtcgatgaggagcgcgcgcagttcgccgcctaccaggcgtcgttcgcggacgccgacgcc
gccgcggaggggaactga
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