Streptomyces alboniger: CP975_03035
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Entry
CP975_03035 CDS
T06908
Name
(GenBank) amino acid adenylation domain-containing protein
Organism
salw
Streptomyces alboniger
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
Condensation
AMP-binding
PP-binding
AMP-binding_C
Motif
Other DBs
NCBI-ProteinID:
QEV16611
UniProt:
A0A5J6HE30
LinkDB
All DBs
Position
complement(692980..713001)
Genome browser
AA seq
6673 aa
AA seq
DB search
MTSSTPSNSASNSASDPADSTRQPSRPSRQARAEALPEDMREALRRRLAGRTGGAAPAAR
QGIPRADRERPLPLSFAQQRLWFLDRLRPGDARYNSAVALRLTGAPDQEALRAALTAVVA
RHEALRTTFEETEGRPVQRVHPAGPVPLPVRDAGDLHKDLLAEYSRPFDLSSGPLLRALL
LRESATSHVLLLTAHHIITDGWSTGIVLDELCTAYDAFAQGAAPALPPVATQYPDFAAWQ
RARLSGARLDGELAHWRQRLAGAVAPELPLDRPRRGEEAGEGAVHSFAVPARLTARLRDL
ARQQHTTLHTALVATAQALLARWSGQDDITVGSLTPGRSRTDLERSVGFFVNTVVLRTPV
EASGSFRELLALAAETVGDAFAHGDTPFERVVEAVGAPREAGRNPLFDVMVLLHPDPPAA
TAPRGLTITPVAVPRQAATFDLSVEFVPDGEGLTGLLEYRTDLFDAATAERMAGQLTRLL
EGACAAPDRALGSLPLLSEAETRRVVHDWNPAPLPVTDTVHPELFERRAARTSDALALVA
GGERLDYATLNARANRLAHHLIARGAGPERLVALRLPRTADMIVAILAVWKSGAGYLPLD
PALPEERVRFLLDDARPALVLDETVLRAVPADSPDTDPTDADRRAPLAADHTAYVIYTSG
STGRPKGVTVTHRAAAHLLAAHRAGFVAEAGGGPLRVALTASFSFDTSLEGVLLMADGHP
LHLVDETTRMDPAALVEYVVEHRVDFLDVTPSYLRQLLPAGLLTDPRHHPRVLMLGGEAV
GPALWRELAAHPDVTAHNFYGPTECTVDALSCRIDGGDRPLVGRPLPGVRAYVLDDRLQP
VPPGVGGELYLAGGQLARGYAGRPGLTAARFLPDPFGGPGERMYRTGDLARWTTDGRLDY
LGRADDQVKVRGHRIEPGEIEAALLALPAVAAAAVAALPDPHGHTRLAAYVVPAPDAPRP
APADLRAALREVLPDALVPSSFTSLDALPLTTSGKLDRRALPMPENTAQEREFVAPRTPG
EETLAGIWAEVLGVARVGVTDNFFELGGDSILSIQAVSRARAAGLHIGSQDVFRHQTVAD
LAAAASRRTTAVPAPRRPHDAGPAPLTPVQEWFFATHGPLRHFAMSMLLDLPHNLDEGAL
DRALHAVVARHPALCTRFTSTDGAWRQHPGTGPATGLLTRHDAGTPPAEAAEAARAALDP
ATGALLRAALLPGGERPQLFLTAHHLAVDSVSWRVLLADLEQAYRQAAAGEEPRPEPEHT
PFADWARTLTERVRAGDLDDGLPHWTRETATPRTPLPVDLPGTPLAGSVRTVRTRVDRDT
TEALLRRVPGAYRTQVNDVLLSALGRVLADWSGTDRVTVALEGHGREEELDEGADLSRTV
GWFTTQYPVTLIPAGPDDWGTTLKSVKEQLRAVPRRGLGYQALGHLGSPRPEARALGRLP
LPDVCFTYHGQWEAPAAGDFAPVADVPGRDMDPDAPLDHLLDVSALVTDGELEITWHYSD
QVHREDTVRGLAAGMARALAAIAEHCARPGAGGRTPSDFPLARLDQAGVDRLVGDGRDVE
DLLPLTPLQEGMLFHRLVGGDDDVYVDQAALLLQGVSDPDALALAWQRVTDRTPALRTSV
VWEGVPVPLQVVHRRVEVPLTQLDWREVDAAERAERLDRLRADDLACGLDLGTAPLMRLT
FVRIPDARLHLLWTSHHLILDGWSLAQVLTEVSEEYAALTTGAEPRPPARRPFGDYVRWL
AGQDTEAAHAHWRTALDGFATPTPLPADRVRRPGHETRSADVHTSALSDEVSAQLAQSAR
SAGLTLGTVVQGAWALLLSRYSAERDVLFGTTVSGRPDDLPGAESMVGMFINTLPTRVHV
DGSRTAAAWLRDLQEEQAQARRFAAVSLAELTSLSDVPAGSPLFDSMVAFENYPFDEARS
ATTGIRLTDVSSRDATNFPLVLRAYQGERFGFDLAYDPELFDARTVRALGDRLCLLLTEL
ADDPERPVRSLAWTTAEERRRMLTDWNGTEEGRPTDTLDALFAAQAARTPDAEAVTCGDE
RLDYATLDARASRLAHRLAELGAGPETFVALALPRSADLVVAVLAVLKTGAAYLPLDPRL
PGERVRRMLADAGPVALVTTRQTVAPVTTEQTATAGPDVPRLLLDDPRVRADLARRPAAG
PTGRALPESPAYAIYTSGSTGTPKGVIVPHANVVRLFTRTRHWFGFGADDVWTLFHSYAF
DFSVWELWGPLLHGGRLVVVPEDTARSPEDFLRLLADEQVTVLNQTPSAFYPLIRADAEH
PDVGARLALRTVVFGGEALDVGRLADWYARHADTAPRLVNMYGITETTVHVTYAGLDRRA
AHSGALSPIGTGIPDLRLYVLDDTLQPVPPGAVGELFVAGEGVARGYLNRPGLTATRFLA
DPFGRPGTRMYRTGDRARWRADGTLEYLGRADQQVKIRGYRIEPGEIEAALHTHPGVGAA
AVGVYEDTAGTRRLVAHVVGTGTGGTSTSTGTGTGGARLGECATPPPAAELRAHLEGLLP
AHMVPAAYVPMAALPLTANGKLDRRALPAPGPDGFAADGTRTAPRTPAERLVAAAWTDVL
DTDEIGVDDDFFALGGDSILAVRVTSRLRAAFGTDVSPRLLFTHPTLLALAVALGEPGGA
DTADVIPATAPGAPAPLSYAQQRLWFLDRFEPGSTEFTTLSVLRLRGPLDSAALRTALDG
VVARHEALRTTFAEHDGQARQIVHPPRPVDLPVLDLPDDAALDALVDRIAAAPFDLAAGP
LLRAHLARFAADEHVLVLAVHHIVTDGWSVGVLARDLGELYAAALADRRPELPALPVRYS
DYAAWQRSRADRAENELAYWRRALDGVIPLDLPTDRPRPAVRTRDGALLTFTLPAALTER
LRERSREADATLYMTLVTACQILLARWAGQEDVTVGTVTAGRERSELHDLVGMFVNTLVL
RAKVRPGVPFRDLLAEVRDTALEAFAHQEVPFERVVDALQPERDTSRTPLFQVMVALHNL
GAEPLRLPGLTAEPVTPPVRVATYDLAFDFVEGEDGLTGHLEYNTGLFDADTAERLAARL
RVLLEAAAEDPGRNVDRLPLMTDDERQRVLRHGEGTRLPEPDTTFPALFEAQAARIPRHT
ALAARDTTLDFAALNQRANRLAHHLIAQGAGPEDVVAVRLPRTSESMVALLAVLKAGATL
LCLDPALPAERQDFLLADARPHTLLTGLDAVPWDRLPAHDPTDADRVRPLLPANAAYLIY
TSGSTGRPKGVAVEHRHLVNLCHDHRTGLLAPHTADGRRLRAALSASFSFDTSWEGPLLL
ALGHEVHLIDEDVRLDPQAFCAHIAAHRLDLVNVTPSYLRELTAAGLLATGRHHPRLLLV
GGEAVTPAVWRDLVRAEQDLGVAVYNMYGPTETTVDAVYARCAAQPHRPVIGRPGGNLRA
YVLDAALRPVPPGTPGELYLAGAQVARGYLNRPGLTAARFLADPFGPPGERMYRTGDRAR
WDREGLLEFLGRADEQIKIRGFRIEPGEVEATLLDQPDITDAAVAARDNAGRLMLVGYVV
PATDRVPSADALRLALRRTLPDHMVPAAFVPLTRIPRTTSGKTDRRALPAPPAQPDSGTP
YVAPRAGTEERLAAIWAEVLGVERVGARDNFFALGGDSILSIQIVSRARQAGLALATKDV
FRHQTVAELALCVQESAPKQDTAEEPAEAPLTPIQRWYLDGRTPGQRLRFTMTQRLELAP
DTTGPALQAATDALVRHHAALRTRFRHTADGWRQNVLPEAPDGVFTRHDAAGLDDTALEA
EVQRLTDEAQSALDPTTGRVVRVLFFDRGPGRPGQLVITAHHLVIDGVSWRILLADLETA
QRAAALGRPVELPPTGTSYGHWAARLDRHTRSGALDADLPYWTRTGTAPAALPAGRPGPN
THGTATTLSVTLDERTTEALLRAVPQTYRTQVNDVLLSALGRTLARWCGRDTVLLGVEGH
GREELFADVDLSRTVGWFTAEFPLALRVAPDADWHDTLRSVKEQLRAVPLHGLSHGALRH
LVPGSPLAGAPAPQVGFNYHGQWDTDGGSDGLLGGALPPAGRDTDPDEPRPYLLDITGVV
QEGRLELGWTYPAAVYDQSTVHRLADDMLAALREIVAHCADPEAGGRTPSDFPLAGLDQE
HIDRLLGTGRHVEDVLPLTPLQSGMLFHGLVDTEHAYFDRTAVRLSGVADPGAFAAAWQH
VTDRTPALRTSVHWHGLPHPVQIVHRHAELPVSHLDWRTLTPAERADATERLLAEDRAAG
MDLGTAPLTRLTLAALPGDEVLLVWSTHHIVLDGWSTGQLLTEVCERYAALTGGPDQAPP
VRRPFADFLHWLREQDETAAERHWAETLADFTARTPLPYDRTPAEAHRARSAAAVHHELD
AGASRRLRESAARAGVTVNTVVEGAWALLLARSGGRDDVVFGTTVSGRPAELPGVEGMIG
MFINTVPTRVRIPAGPVLPWLRDLQERQSDARRFDFLALPRIQAVSEVPSGEALFDSMVV
FENYPVDESATARTGVRVEEVRADDATTFPWCLRAHLGERLGFDLAYDPDLFDPATVQRA
AARLAGLLTALADGFDTDLTDLDVLAPADRELLAAWNTTARRAAPRSPVDLFAEQVRRTP
DAPAIHDGEREVTYRQLHDWARSLADRLRTDGLAPEDRVALLLDRSAELVVAQLAVLLAG
GAYVPVDTRAPEERRRTMLAQAGATLQLTATEVAAARPGTPRRGGRPAPSVDPDQLAYVM
FTSGSTGLPKAVAVRHRDVAALATDSRFADGVCDRVLLHSPVAFDAATFEVWAPLLNGGC
VVVAPGGVDAASLRRLAADGGLTALWLTAGLFRLLAQDAPDCFRGLAQVWTGGDVVPAQA
VRRVLDACPGLTVVDGYGPTETTTFATAFALTDPAAVPGTIPIGRPLDDMRALVLDPRLR
PVPPGCPGELYLAGEGVARGYLGRPGDTAGRFLADPLGPPGARMYRTGDLARRRPDGTVD
FLGRADDQVKIRGFRVEPGEVEAALAAHPDVVDVAVLAREDRPGAKRLVAYVVGPAGRDA
EELRTFAARTLPDYLVPTTVVPLTALPLSRNGKVDRAALPAPDALPGPERVEPRTEAERR
TADVFGEVLASEPPGVEDDFFQLGGDSILSIRLASRLAETFDTDLTPRAVFTHPTPAALA
RLLGERRGSGRAPLVPVTRDAVAPMSHAQQRLWFLHEFEPGGAEYVTALALRLRGTLDTD
ALRAALGAVVARHESLRTTFDSVDGHGIQRVHPPRDVPLPVHDLCRLGAAEQEPAVRRLL
AEERVRPFDLREGPLLRAGLIRLAEHDHVLTLALHHIVTDGWSTSVLVGDLAHFYRSELG
VRTVELAPLPVQYADYAHWQRTAGAAEADEHLAYWKEQLADTAPLELPTDRPRPAVRTSA
GATARLVVPAATARRLTRLARDHGTTLFTTLVAAAQSYLARLSGTEDIAVGTVTAGRDRP
ETQALVGFFVNTLVLRSRAEADRPFTGFLGDVRQTVQDAFAHQDVPFERVVDEVQPVRDT
SRSPLFQVMVVLQNTPAVALDLPGLDAADVEPESEQAAFDLTLEFAETGSGELHALLTYN
TDLFDAATAERMAGQFGTLLHAVAEDPSRPLGALPLASDDERENLLEQGRGTFRPVPEST
LPALFERQVARTPDAVALFEGDRELTYADVDRAANRLARRLVGDGVGPERVVALALPRSA
AAVVAQLAVTKAGGAFLPVDPDYPPQRREFMIRDAGAHLVLDDPAEVWSTEGPDTALTDA
DRTTALTPAHPAYVIYTSGSTGTPKGVVVTHRGLASFAAAAAEQYAAGPGDRVLQFASPS
FDASVLELCVSLLSGAALVTGEEGPLVGERLAEVLAERRVSHTLIPPAALATLPPETAAA
LPGLRTLIVGAEACPADLADTWAPGRRMVNSYGPTEATVVATWTGPLTPGTGTPTIGRPS
GATRVYVLDAALRPVPPGVTGELYIAGPGLARGYLGRPRLTAQRFLPDPFGTPGERMYRT
GDLVRWTADGQLRFAGRTDDQVKLRGFRIEPGEIESALRRSPLVRDAAVVVRAGEGPGAP
TRLVAYVVPVKPSKAGTPGTEASGTALPVGELRLHLAGSLPPHMVPSVFVPLDRLPLTPN
GKTDRRALPAPGAAQAADGPRTAPRTDTERRIARIWADVLGIKEVGADDNFFALGGDSIL
SMQVVSRMRRDGLHVATRDLFTHQTVAELATAVRAAPRSSAEGPVTGEVPLTPIQEWFLA
TPRAAHHHFNQSALLELDGRPDPRALSTALDALLEHHDALRMCFTQDEHGWRQFNPPPAA
GDGILVRHDLTGLSAEEADAAMAKAADELHASFDLARGPHLRAALFTGDPDRPAYLLLVV
HHLVVDAVSWRVLRDDLETAYRQALQGDPVGLGERGTSFRAWSLRLAAHVAEGGLDHELP
HWERTVGAEPAPAGPATATHEGPTATVSVELDEDDTTALLRSAPTAYRTRVNDVLLTALA
LALARWTGHDRVRLDLEGHGREDLLDGVDLSRTVGWFTTVYPVALQVSDPGDLGPDRDWR
SLVKSVRRQLRAVPANGIGYGALRTFGPPEVRERLGAQAHSQVVFNYLGQWDARPETADS
GLVRAEHGSFGQDHDPRDPGSHPVEVVGAVQHGRLAFTWHHRPGLHDTATVRRAAEDFAE
ALRHLARHARGGR
NT seq
20022 nt
NT seq
+upstream
nt +downstream
nt
atgacgtcttcgaccccttcgaactccgcttcgaactctgcttcggatcccgctgactcc
acacgtcagccgtcccgcccctcccggcaggcccgtgccgaggccctgcccgaggacatg
cgggaggcgctgcgacgccggctcgccggccggaccggcggcgccgccccggccgcccgg
cagggcatcccgcgcgccgaccgggagcgccccctgccgctgtccttcgcacagcagcgg
ctgtggttcctggaccggctgcggcccggcgacgcccgctacaacagcgcggtcgccctg
cgcctcaccggcgcgccggaccaggaggcgctgcgcgcggccctgaccgccgtcgtggcc
cggcacgaggcgctgcgcaccaccttcgaggagaccgaagggcgcccggtgcagcgcgtc
cacccggcgggcccggtgccgctgccggtccgggacgcgggcgacctgcacaaggacctc
ctggccgagtactcccgccccttcgacctgagcagtgggccgctgctgcgcgccctgctg
ctgcgcgagtccgccacctcccacgtcctgctgctgacggcccatcacatcatcacggac
ggctggtcgacgggcatcgtcctggacgagctgtgcaccgcctacgacgccttcgcgcag
ggcgccgcgcccgccctgccgccggtggccacgcagtacccggacttcgcggcgtggcag
cgcgcccggctctcgggcgcccgcctcgacggcgaactcgcccactggagacagcgtctg
gccggggctgtggcgcccgagctgcccctggaccggccgcggcgcggcgaggaggcgggc
gagggcgccgtccactccttcgccgtcccggcccgtctgaccgcgcgcctgcgcgacctc
gccaggcagcagcacaccaccctgcacaccgccctggtcgctaccgcacaggcgctgctg
gcccgctggtcgggccaggacgacatcaccgtcggctccctcacgcccggccgctcccgc
accgacctggaacgcagcgtcgggttcttcgtgaacaccgtcgtgctgcgcaccccggtg
gaggcctccgggtccttccgtgaactcctcgccctggcggccgagacggtgggcgacgcc
ttcgcccacggcgacaccccgttcgagcgggtcgtggaggcggtgggcgcgccccgcgag
gccggccgcaacccgctgttcgacgtgatggtcctgctgcaccccgacccgcccgccgcg
accgccccgcgcgggctcaccatcactccggtcgccgtgccccggcaggcggccaccttc
gacctgagcgtcgagttcgtgccggacggtgagggcctgaccggcctccttgagtaccgc
accgacctgttcgacgcggccaccgccgagcggatggccggacagctgacacgtctgctc
gaaggcgcctgcgccgcgccggaccgagcgctgggcagcctgcccctgctctccgaggcg
gagacccgacgggtcgtccacgactggaaccccgccccgctccccgtcacggacaccgtc
caccccgaactgttcgagcgccgcgcggcccggacctccgacgccctcgcgctcgtcgcg
ggcggcgaacggctggactacgccacgctcaacgcccgcgccaaccggctcgcccaccat
ctcatcgcccgcggcgcaggtcccgaacggctggtcgcactgcggctcccgcgcaccgcc
gacatgatcgtcgcgatcctcgccgtctggaagtccggcgcgggatatctcccgctggat
ccggccctgcccgaggagagggtccggttcctgctggacgacgcccgcccggccctggtc
ctcgacgagacggtcctgcgcgccgtgcccgcggactccccggacaccgaccccacggac
gccgaccggcgcgccccactggcggcggatcacaccgcgtacgtcatctacacctccggc
tccaccggccggccgaagggcgtcaccgtcacccaccgcgcggcggcgcacctgctcgcc
gcccaccgggccggcttcgtcgccgaggcgggcggcggccccctgcgggtcgcgctcacc
gcgtccttctccttcgacacctccctcgaaggcgtgctgctgatggccgacggccatccg
ctgcacctggtcgacgagaccacccggatggacccggccgcgctggtcgagtacgtcgtc
gagcaccgcgtcgacttcctcgacgtcaccccgtcctacctgcggcaactgctgcccgcc
ggactgctcaccgacccccggcaccacccccgggtcctcatgctcggcggtgaggcggtc
ggccccgcgctctggcgcgagctggccgcccacccggacgtgaccgcccacaacttctac
ggccccaccgagtgcacggtcgacgccctgtcctgccgtatcgacggcggggaccgcccg
ctggtgggccgccccctgcccggcgtacgggcctatgtgctggacgaccggctccagccg
gtgccgcccggcgtcggcggcgagctgtacctggcgggcggccagctcgcccggggttac
gccggacggccgggcctgaccgcggcccgcttcctgcccgacccgttcggcggacccggg
gagcggatgtaccgcaccggcgacctggcccgctggaccaccgacggccgactcgactac
ctcgggcgcgccgacgaccaggtcaaggtgcgcggccaccgaatcgagcccggcgagatc
gaggccgccctgctcgcgctgcccgccgtcgccgccgccgcggtcgccgccctgcccgac
ccgcacggccacacgcgcctcgccgcctacgtcgtccccgcacccgacgcgccccggccc
gcccccgccgacctgcgcgcggccctgcgtgaggtgctgcccgacgccctggtgccgtcc
tccttcacctcgctggacgcgctgccgctgaccaccagcggcaagctggaccgccgagcc
ctgcccatgccggaaaacaccgcgcaggagcgggagttcgtcgccccgcgcacccccggc
gaggagaccctggccggtatctgggccgaggtgctcggagtggcccgggtgggtgtcacg
gacaacttcttcgagctgggcggcgactcgatcctgagcatccaggccgtctcccgggcc
cgcgccgcgggcctgcacatcggttcgcaggacgtcttccgccaccagaccgtcgccgac
ctggccgccgccgcgtcccgccgcaccaccgccgtgcccgcgccccgccgcccgcacgat
gccggacccgcgccgctcacccccgtacaggagtggttcttcgccacgcacgggccgctg
cggcacttcgccatgtcgatgctgctcgacctgcctcacaacctcgacgagggggccctg
gaccgggcactgcacgccgtggtggcacgccacccggccctgtgcacccgcttcacctcc
accgacggcgcctggcggcagcaccccggcaccggcccggcgaccggactgctcacccgc
cacgacgccggaaccccgcccgccgaggccgcggaagcggcccgcgcggccctggacccg
gcgaccggcgccctgctgcgcgcggccctcctgcccggcggggaacgcccgcaactgttc
ctcactgcccaccacctggcggtcgacagcgtctcctggcgggtgctcctcgccgacctg
gagcaggcctaccgacaggcggcggccggcgaggaaccccgaccggaaccggagcacacc
ccgttcgccgactgggcgcggaccctcaccgaacgcgtccgcgcaggcgacctcgacgac
ggcctgccccactggacgcgcgagacggcgacgccgcgcaccccgctccccgtcgacctg
cccggcaccccgctcgccgggtccgtgcgcaccgtccgcacacgcgtggaccgggacacc
accgaggcactcctgcggcgggtaccgggcgcgtaccgcacccaggtcaacgacgtgctg
ctgagcgcgctgggccgggtgctcgccgactggtccggcaccgaccgggtgaccgtcgcc
ctggagggccacggccgcgaggaggaactggacgagggcgccgacctgtcccgcacggtc
ggctggttcaccacccagtacccggtcaccctgatcccggccggaccggacgactggggg
accaccctcaagtccgtcaaggaacagctgcgcgccgtgccccgccgcggcctgggctac
caggcgctcggccacctcggctcaccccggcccgaggcccgggcgctcggccgactgccg
ctgcccgacgtctgcttcacctatcacgggcagtgggaagcgcccgccgcaggagacttc
gcgcccgtcgccgacgtccccggccgggacatggaccccgacgcgccactggaccacctc
ctcgacgtgtccgccctcgtgaccgacggcgaactggagatcacctggcactacagcgac
caggtgcaccgcgaggacaccgtccggggcctggccgcgggcatggcgcgggcgctcgcc
gccattgccgagcactgcgcccgccccggcgcgggcgggcgtacaccctccgacttcccg
ctggcccgcctggaccaggccggtgtggaccggctcgtcggtgacggccgggacgtcgag
gacctgctgccgctcaccccgctccaggagggcatgctcttccaccgtcttgtcggcgga
gacgacgacgtgtacgtggaccaggccgcgctgctcctccagggcgtgagcgacccggac
gccctcgccctggcctggcagcgggtgaccgaccgcacccccgccctgcgcacctcggtg
gtgtgggagggcgtcccggtgccgctccaggtcgtacaccgccgggtcgaagtccccctc
acacagctggactggcgcgaagtggacgcggcggagcgggccgagcgcctcgaccggctg
cgcgccgacgacctcgcctgcggcctcgacctgggcacggcgcccctgatgcggctcact
ttcgtccggatccccgacgcccggctgcacctgctgtggacctcccaccacctgatcctg
gacggctggagcctcgcccaggtgctcaccgaggtgtccgaggagtacgcggcgctcacc
accggcgccgaaccccggccaccggcccgacggccgttcggcgactacgtgcgctggctg
gccggccaggacaccgaggcagcccacgcgcactggcggaccgccctcgacgggttcgcc
accccgaccccgctgccggccgaccgcgtccggcgccccggccacgagacccgctccgcc
gacgtgcacacgagcgcgctgtccgacgaggtctccgcccaactggcgcagtccgcccgg
tcggccggactcaccctcggcaccgtggtgcagggcgcctgggcactgctcctgtcgcgc
tacagcgccgaacgggacgtgctgttcgggaccaccgtctccggacggcccgacgacctg
cccggcgccgagtcgatggtgggcatgttcatcaacaccctgcccacccgcgtccatgtg
gacggcagccgcaccgccgccgcctggctcagggacctccaggaggaacaggcgcaggca
cggcgcttcgcggcggtgtccctcgccgaactgacctcgctgagcgacgtgccggccggg
agccccctcttcgacagcatggtggccttcgagaactaccccttcgacgaggcgcgttcg
gccacgaccgggatacgtctcaccgatgtctcctcccgggacgccaccaacttcccgctg
gtgctgcgggcctaccagggcgagcggttcggcttcgacctcgcctacgaccccgaactg
ttcgacgcgaggaccgtacgcgccctcggcgaccggctctgcctgctgctcacggaactg
gccgacgaccccgagcggcccgtgcgctccctggcctggaccaccgccgaggaacggcgg
cggatgctcaccgactggaacggcaccgaggagggccggcccaccgacacgctggacgcg
ctgttcgccgcccaggccgcccgcacccccgacgccgaggccgtcacctgcggcgacgaa
cgcctcgactacgccaccctggacgcacgggcaagccgtctcgcccaccggctcgccgaa
ctcggcgccgggcccgagacgttcgtcgccctcgcgctgccccgctccgccgacctcgtc
gtcgcggtcctcgccgtcctcaagaccggcgccgcctacctgcccctcgacccccggctg
cccggggagcgcgtccggcggatgctcgccgacgccggtcccgtcgccctggtcaccacg
cggcagaccgtcgccccggtcaccaccgagcagaccgcgacggccggcccggacgtgccc
cgcctgctgctcgacgacccgcgggtgcgcgccgacctcgcccgccgcccggccgcggga
ccgacggggcgcgcgctgcccgagagccccgcctacgccatctacacctccggctccacc
ggtacgcccaagggcgtgatcgtcccgcacgccaacgtggtcaggctcttcacccgcacc
cggcactggttcggcttcggagccgacgacgtgtggacgctcttccactcctacgccttc
gacttctcggtgtgggagctgtggggcccgctgctgcacggcggccggctcgtggtcgtc
cccgaggacaccgcccgctccccggaggacttcctgcgcctgctcgccgacgagcaggtc
accgtgctcaaccagacgccgtccgcgttctacccgttgatccgagcggacgccgaacac
ccggatgtcggcgcccggttggcgctgcgcacggtcgtcttcggcggcgaggccctggac
gtgggcagactcgccgactggtacgcccgccacgcggacaccgcgccccgcctggtgaac
atgtacggcatcaccgagaccaccgtgcacgtgacgtacgccggtctcgaccggcgggcc
gcccactccggtgccctgagccccatcggcaccggcatccccgacctgcggctctacgtc
ctcgacgacacgctccagccggtaccgccgggcgccgtgggcgaactgttcgtggccggt
gagggggtggcgcgcggttacctgaaccggcccggactgaccgcgacccgctttctcgcc
gaccccttcggccgtccgggcacccgtatgtaccgcaccggggaccgggcgcgctggcgg
gccgacggcaccctggagtacctgggccgcgccgaccagcaggtcaagatccgcggctac
cgcatcgagcccggcgagatcgaggccgccctgcacacccaccccggcgtcggcgcggcc
gccgtcggcgtgtacgaggacaccgccgggacccgccgcctcgtcgcccacgtcgtcggc
accggcacgggcggcaccagcaccagcaccggcaccggcaccggcggcgcccgcctcggg
gagtgcgccacgcccccgcccgccgccgaactccgcgcccacctcgaaggcctgctgccc
gcgcacatggtgcccgccgcctatgtgccgatggccgcgctgccgctcaccgccaacggc
aagctcgaccggcgcgccctgcccgcgcccggccccgacggcttcgccgccgacggcacg
cggaccgcgccgcgcacccccgccgagcggctcgtcgccgccgcctggacggacgtactg
gacaccgacgagatcggcgtcgacgacgacttcttcgccctgggcggcgactccatcctc
gccgtccgtgtcacctcccgactgcgcgccgccttcggcacggacgtctcgccccggctg
ctgttcacccaccccacgctcctcgccctcgccgtcgccctgggcgagccgggcggcgcg
gacaccgccgacgtcatcccggccaccgcccccggcgccccggcgcccctgtcgtacgcc
cagcaacgcctgtggttcctcgaccggttcgagccgggcagcacggagttcaccaccctg
tccgtgctgcggctgcgcggcccgctggacagcgcggccctgcgtaccgccctggacggt
gtggtcgcccggcacgaggccctgcgcaccacgttcgccgaacacgacggccaggcacgt
cagatcgtccacccgccccggcccgtggacctgccggtgctcgacctcccggacgacgcc
gccctggacgcactcgtggaccggatcgccgccgctcccttcgacctggccgccggcccc
ctgctgcgggcccacctggcgcgcttcgccgccgacgagcacgtcctcgtcctggccgtc
caccacatcgtcaccgacggctggtccgtcggcgtactggccagggacctcggcgagctg
tacgcggccgccctagcggaccgccgccccgagctgcccgcgctgcccgtccgctacagc
gactacgcggcctggcagcgttcccgcgccgaccgcgcggagaacgaactcgcctactgg
cgccgggctttggacggcgtgatcccgctggatctgcccaccgaccggccgcgcccggcc
gtccgcacccgcgacggcgccctgctgaccttcaccctgcccgccgcactcaccgagcgg
ctgcgcgaacggtcacgggaggccgacgccaccctctacatgacgctggtgaccgcctgc
cagatcctgctcgcccggtgggcgggacaggaggacgtcaccgtcggcaccgtcaccgcg
ggacgcgagcggtccgaactgcacgacctggtcggcatgttcgtcaacactctggtgctc
cgcgccaaggtccgccccggtgtgcccttccgggacctgctcgccgaggtgcgcgacacc
gccctggaggcgttcgcccaccaagaggtgcccttcgagcgcgtggtggacgccctccag
cccgagcgggacaccagccgcacccccctgttccaggtcatggtcgccctgcacaacctc
ggcgccgagccgctccgactgcccggcctgacggcggagccggtcaccccgccggtgcgc
gtcgccacctacgacctcgccttcgacttcgtggagggcgaggacggactcaccgggcac
ctggagtacaacaccggtctgttcgacgccgacaccgccgaacgcctggccgcccggctg
cgcgtcctgctggaggccgccgccgaggacccgggccggaacgtggaccggctgccgctg
atgaccgacgacgagcggcagcgcgtactgcgccacggggagggcacccgcctgcccgag
ccggacaccaccttccccgccctgttcgaggcccaggcagcccgcatcccgcggcacacc
gccctggccgcccgcgacaccacgctggacttcgccgcgctgaaccagcgcgccaaccgg
ctcgcccaccacctcatcgcccagggcgcaggccccgaagacgtggtcgccgtccggctg
ccgcgcacctccgagtcgatggtggcgctgctcgccgtcctcaaggcgggcgccaccctg
ctctgcctggaccccgcgctccccgccgaacggcaggacttcctcctcgccgacgcccgc
ccgcacaccctgctgaccggcctcgacgcggtgccctgggaccggctgcccgcccacgac
ccgaccgacgccgaccgcgtccggcccctgctgcccgccaacgccgcctacctcatctac
acctccggctccaccggccgccccaagggcgtcgccgtcgaacaccggcacctggtcaac
ctctgccacgaccaccgcacgggcctgctcgccccgcacaccgccgacggacggcggctg
cgggccgcactcagcgcctccttctccttcgacacctcctgggaaggaccgctgctcctc
gctctcggccacgaggtccacctgatcgacgaggacgtacgcctcgacccgcaggcgttc
tgcgcccacatcgccgcacaccgcctcgacctggtcaacgtcacgccgtcctacctgcgc
gaactcaccgccgcaggactactcgccaccggccgccaccacccgcgccttctgctcgtc
ggcggcgaggccgtcaccccggccgtctggcgcgacctcgtgcgcgccgaacaggacctg
ggcgtcgccgtgtacaacatgtacgggccgaccgagaccaccgtcgacgccgtctacgcc
cgctgcgccgcccagccgcaccgcccggtcatcggccgccccggcggcaatctgcgcgcc
tacgtcctcgacgccgccctgcgcccggtgccgcccggcacgcccggcgagctgtacctg
gccggggcgcaggtggcccgcggctatctgaaccggcccggcctcaccgccgcccgcttc
ctcgccgacccgttcggcccgcccggcgagcggatgtaccgcaccggcgaccgggcccgc
tgggaccgggaagggctcctcgaattcctggggcgggcggacgagcagatcaagatccgc
gggttccggatcgagcccggtgaggtggaggccaccctcctggaccaaccggacatcacc
gatgccgccgtcgccgcccgcgacaacgcgggccgcctcatgctcgtcggctatgtcgtg
cccgccaccgaccgcgtcccgtccgcggacgccctgcgcctcgcgctgcgccgcaccctg
cccgaccacatggtgcccgccgcgttcgtcccgctgacccgcatcccccgcaccaccagc
ggaaagacggaccggcgcgccctgcccgccccgcccgcacagcccgacagcggcacgccc
tacgtcgccccccgggccggcacagaggaacgcctggccgcgatctgggcggaggtgctc
ggtgtcgaacgcgtcggcgcccgcgacaacttcttcgcgctcggcggcgactccatcctg
agcatccagatcgtctcccgcgcccgacaggccggactcgccctcgccaccaaggacgtc
ttccgccaccagaccgtcgccgaactcgccctgtgcgtacaggagtcggcgccgaagcag
gacaccgccgaggaaccggccgaggcgcccctcaccccgatccagcgctggtatctggac
ggccgcacacccgggcagcgcctccggttcaccatgacccagcgcctcgaactcgccccg
gacaccaccgggcccgcgctccaggccgccaccgacgccctcgtacgccaccacgccgcc
ctgcgcacccggttccgccacaccgccgacggctggcgccagaacgtcctgcccgaggca
ccggacggcgtcttcacccggcacgacgcggcaggcctggacgacacggcactggaggcc
gaggtccagcggctgacggacgaggcgcaatccgccctcgaccccaccaccgggcgggtc
gtgcgcgtactgttcttcgaccgcggcccgggacggcccggacaactcgtcatcaccgca
caccacttggtcatcgacggcgtctcctggcgcatcctgctcgcggacctggagaccgcc
cagcgggcggcggcgctcggccggcccgtggaactgccccccaccggcacgtcctacggc
cactgggccgcccggctcgaccggcacacccgatccggcgcactcgacgccgacctgccg
tactggacacgcaccggcacggcaccggccgccctgcccgcgggccgacccggccccaac
acccacggaaccgccaccaccctctccgtcaccctcgacgagcggactaccgaagccctg
ctgcgcgcggttccgcagacctaccgcacccaggtcaacgacgtcctgctcagcgccctc
ggccgcaccctggcccgctggtgcggacgcgacaccgtcctgctcggcgtcgagggccac
ggcagggaggaactgttcgcggacgtcgacctgtcgcggaccgtcggctggttcaccgcc
gagttcccgctcgccctgcgcgtcgccccggacgccgactggcacgacacgctccgctcg
gtgaaggagcaactgcgcgcggtgccgctgcacggcctgagccacggcgccctgcgccac
ctcgtgcccggcagcccgctcgccggggcccccgccccgcaggtcggcttcaactaccac
ggccaatgggacacggacggcggctccgacggcctgctgggcggcgccctgcccccggcc
ggccgggacaccgacccggacgaaccccggccctacctcctggacatcaccggcgtggtc
caggagggcaggctcgaactcggctggacctaccccgccgccgtctacgaccagagcacc
gtccaccggctcgccgatgacatgctcgcggccctgcgggagatcgtggcccactgcgcc
gaccccgaggcgggcggccgcaccccctccgacttcccgctcgccggcctcgaccaggag
cacatcgaccggctcctcggaacaggccgccacgtcgaggacgtcctgccgctcaccccg
ctccagtccggcatgctcttccacggcctcgtggacaccgagcacgcctacttcgaccgc
acggccgtacggctgtccggcgtcgccgacccgggggccttcgccgccgcctggcagcac
gtcaccgaccgcaccccggcgctgcgcaccagcgtccactggcacggcctgccgcacccg
gtccagatcgtccaccgccacgcggaactgcccgtcagccacctcgactggcgcacgctc
acacccgccgagcgcgccgacgcgaccgagcggctgctcgccgaggaccgcgccgccggc
atggacctcggcacggccccgctcacccggctcaccctggccgccctgcccggcgacgag
gtgctcctcgtgtggtccacccaccacatcgtcctcgacggctggagcaccgggcagttg
ctcaccgaggtctgcgagcgctacgccgcgctcaccggcggccccgaccaggcgcctccc
gtacggcggcccttcgcggacttcctgcactggctgcgggagcaggacgagacggcggcg
gagcggcactgggccgaaaccctcgccgacttcaccgcccggaccccgctgccgtacgac
cgcacacccgccgaggcccaccgcgcccgttccgccgcggccgtccaccacgagctggac
gccggggcctcgcggcgcctgcgggagagtgccgcccgtgccggagtcaccgtgaacacg
gtggtggagggcgcctgggcgctgctcctggcccgctccggcggacgggacgacgtggtc
ttcggcaccaccgtctccggccgcccggccgaactgcccggcgtcgaaggcatgatcggc
atgttcatcaacacggtgccgacccgggtccgcatacccgcggggccggtgctgccgtgg
ctgcgcgacctccaggaaaggcagagtgacgcccgccgcttcgacttcctcgccctgccc
cgcatccaggccgtgagcgaggtcccgtccggcgaggccctgttcgacagcatggtggtg
ttcgagaactaccccgtggacgagtcggcgacggcccgcaccggggtccgggtcgaggag
gtgcgcgccgacgacgccaccaccttcccctggtgcctccgcgctcacctgggtgaacga
ctcggcttcgacctggcctacgaccccgacctgttcgaccctgccaccgtccagcgcgcc
gcggcccgccttgccggactgctcaccgccctcgccgacggcttcgacaccgacctgacc
gacctggacgtgctcgctccagccgaccgcgaactgctggccgcctggaacaccaccgcc
cgccgggccgcgccgcgcagccccgtcgacctgttcgccgaacaggtgcgccgcaccccg
gacgcacccgcgatccacgacggcgaacgcgaggtgacgtaccgtcaactccatgactgg
gcacgctcactggccgaccggctccgcaccgacggactggcacccgaggaccgggtggcg
ctgctcctcgaccgctccgccgaactggtcgtcgcccagctcgcggtgctcctggccggc
ggcgcctacgtccccgtcgatacccgcgcccccgaggagcgccgccgcaccatgctcgcc
caggcgggcgcgacccttcaactgaccgccacggaggtggcggcggcccggcccgggaca
ccgcggcgaggcggtcggcccgccccgtccgtcgatcccgaccaactggcgtacgtgatg
ttcacctccggctccaccgggctgcccaaggcggtcgccgtgcggcaccgggacgtggcg
gcgctcgccaccgacagccggttcgccgacggggtctgcgaccgcgtgctgctgcactcg
ccggtggcgttcgacgccgccaccttcgaggtgtgggcaccgctcctcaacggcggctgc
gtggtcgtggccccgggcggcgtcgacgcggcctcgctgcgccgactcgccgccgacggc
ggactcaccgcgctgtggctgaccgccggactgttccggctcctcgcccaggacgcgccc
gactgcttccgcggcctcgcgcaggtgtggaccggcggtgacgtcgtaccggcgcaggcc
gtgcgccgggtcctcgacgcctgccccggcctgaccgtcgtggacggctacggccccacc
gagaccaccaccttcgcgaccgccttcgccctcaccgacccggcggcggtacccggcacg
atccccatcggacgcccgctggacgacatgcgggcactggttctcgacccccggctgcgg
cccgttccgccgggctgcccgggcgagttgtacctggccggcgagggcgtcgcccggggc
tacctgggccgtcccggcgacacggccggccgcttcctcgccgacccgctcggccctccc
ggcgcccgcatgtaccgcacgggcgacctggcccggcggcgcccggacggcaccgtcgac
ttcctcggccgcgccgacgaccaggtgaagatccgcggcttccgggtggagccgggcgag
gtcgaggccgccctcgccgcccacccggacgtcgtcgacgtggccgtcctggcccgcgag
gaccgccccggcgccaaacggctcgtcgcctacgtcgtcggaccggccggccgggacgcc
gaggagctgcggaccttcgccgcccgcaccctgcccgactacctcgtacccaccaccgtg
gtcccgctcaccgcgctgccgctcagccgcaacggcaaggtcgaccgggccgccctgccc
gcgccggacgccctgccgggccccgagcgggtcgagccccgcaccgaggccgagcgccgc
acggcggacgtcttcggcgaggtcctcgccagcgaaccgcccggcgtggaggacgacttc
ttccagctcggcggcgactcgatcctcagcatccggctcgcctcccgcctcgccgagacc
ttcgacaccgacctcacaccgcgcgcggtcttcacccacccgacaccggccgccctggcc
cgcctgctcggcgaacggcggggatccggccgcgcgccgctcgtcccggtcacccgcgac
gcggtcgctccgatgtcacacgcccagcaacgcctgtggttcctgcacgagttcgagccc
ggcggcgccgagtacgtcaccgcgctcgccctgcggctgcgcggcaccctggacaccgac
gcgctgcgcgccgccctcggcgccgtggtagcgcggcacgagtcgctgcgcaccaccttc
gacagcgtcgacgggcacggcatccagcgcgtccacccgccccgcgacgtgccactgccc
gtacacgacctgtgccgactcggcgcggcggagcaggaaccggccgtgcgccgcctgctc
gccgaggagcgcgtccgccccttcgacctgcgcgagggcccgctgctgcgcgccggcctg
atccggctggccgagcacgaccacgtactcaccctcgccctgcaccacatcgtcaccgac
ggctggtccacctccgtcctggtcggcgacctcgcgcatttctaccgctccgaactcggc
gtgcggacagtcgagttggctccgttgccggtgcagtacgccgactacgcccactggcag
cgcacggccggcgccgccgaggccgacgaacacctcgcctactggaaggagcaactggcc
gacaccgcaccgctggagctgcccaccgaccggccacggcccgcggtgcgcaccagcgcc
ggcgcgaccgcccggctcgtggtgcccgccgcgaccgcccgccgcctcacccggctcgcc
cgggaccacggcaccaccctgttcaccacgctcgtggccgccgcccagagctacctcgcc
cggctctccggcaccgaggacatagccgtcggcaccgtcaccgcgggccgcgaccggccc
gagacacaggccctcgtcggcttcttcgtcaacaccctggtgctgcgctcccgcgccgag
gccgaccggccgttcaccgggttcctcggcgacgtacggcagaccgtgcaggacgccttc
gcccatcaggacgtgccgttcgaacgggtcgtggacgaggtgcagcccgtccgcgacacc
agccgcagcccgctcttccaggtcatggtcgtcctccagaacaccccggccgtcgccctc
gacctgcccggcctcgacgccgccgacgtcgaaccggagtcggagcaggccgcgttcgac
ctcaccctggagttcgccgagaccggctccggtgagctgcacgccctgctcacctacaac
accgacctgttcgacgcggccacggccgaacggatggcgggacagttcggcaccctgctg
cacgccgtcgcggaggacccctcccgcccgctcggcgcgctgccgctggcctccgacgac
gagcgggagaacctgctggagcagggccggggcaccttccgcccggttcccgaatccacc
ctgcccgccctgttcgaacggcaggtggcccgcaccccggacgccgtggcactgttcgag
ggcgaccgggagctgacgtacgcggacgtggaccgggccgccaaccggctggcccgccgg
ctcgtcggggacggcgtcggaccggagcgtgtggtggccctcgccctgccgcgctcggcg
gcggccgtggtggcgcagctcgccgtcaccaaggccggcggggccttcctgcccgtggac
cccgactacccgccgcagcggagggagttcatgatccgggacgcgggcgcccacctggtc
ctcgacgacccggccgaggtgtggtccaccgagggaccggacacggcactcacggacgcc
gaccgcaccacggcgctcactcccgcccaccccgcctacgtcatctacacctccggttcc
accggcacgcccaagggcgtcgtggtcacccaccggggcctcgcctccttcgccgcggcg
gccgccgagcagtacgcggcgggtcctggcgaccgggtcctccagttcgcctccccgagc
ttcgacgcctccgtcctcgaactgtgcgtctccctgctcagcggcgccgcgctggtgacg
ggcgaggaagggccgctggtcggcgagcggctcgccgaggtcctcgccgagcggcgggtc
agccacacgctgattccaccggcggcgctggccacgctcccgccggagaccgccgccgcc
ctgcccggcctgcgcaccctgatcgtcggcgccgaggcctgtccggcggacctggccgac
acctgggcccccggccgccgcatggtcaactcctacggccccaccgaggccaccgtggtc
gccacctggaccggcccgctcaccccgggcacaggcaccccgaccatcggccgcccgtcc
ggcgccacgcgcgtgtacgtgctcgacgccgccctgcgccccgtaccgcccggcgtgacc
ggcgagctgtacatcgccgggcccggcctggcccgcggctacctgggcaggccgcgactc
accgcgcaacggttcctgcccgacccgttcggcacgccgggggagcggatgtaccgcacc
ggagacctggtccgctggaccgccgacggccaactgcggttcgccggccgcaccgacgac
caggtcaagctgcgcggcttccggatcgagcccggggagatcgagagcgcgctgcgccgc
agcccgctggtgcgggacgcggccgtggtcgtccgcgcgggggaggggcccggcgcaccg
accaggctcgtcgcgtacgtcgtaccggtaaagccgtccaaagccggcaccccgggcacg
gaggcgtccggaaccgcgctgcccgtcggggaactgcggctgcacctggccgggtcgctg
cccccgcacatggtgccgtcggtcttcgtccccctcgaccggctgccgctcaccccgaac
ggcaagaccgaccggcgcgcactgcccgcgcccggggccgcccaggccgcggacggcccg
cggaccgcgccgcgcaccgacaccgaacgccgtatcgcccgtatatgggccgacgtgctc
ggcatcaaggaggtcggcgccgacgacaacttcttcgcgctcggcggcgactccatcctg
agtatgcaggtcgtctcccggatgcgccgcgacggactgcacgtggcgacccgggacctg
ttcacccaccagaccgtcgccgaactcgccaccgcggtccgcgccgcgccccggagctcc
gccgaaggcccggtgaccggcgaggtaccgctcaccccgatccaggagtggttcctggcc
acgccccgcgcggcccaccaccacttcaaccagtcggcgctcctcgaactcgacggccgc
cccgacccgcgggcactgagcaccgcgctcgacgccctgctggagcaccacgacgccctg
cgcatgtgcttcacccaggacgagcacggctggcggcagttcaacccgccgcccgccgca
ggcgacggcatcctcgtacgccacgacctgacgggtctgtccgccgaggaggccgacgcc
gcgatggcgaaagccgccgacgaactccacgcgagcttcgacctggcccgcggcccgcac
ctgcgggcggccctgttcacgggggacccggaccggcccgcgtacctcctcctcgtcgtc
caccacctggtggtggacgccgtctcctggcgcgtcctgcgcgacgacctggagacggcc
taccggcaggccctccagggtgacccggtcgggctgggcgagcgcggcaccagcttccgc
gcatggtccctgcgtctggccgcgcacgtcgccgagggcggcctcgaccacgaactgccg
cactgggagcggacggtgggcgccgaacccgccccggcgggcccggccacggcaacccac
gaggggccgaccgccacggtgagcgtggaactcgacgaggacgacaccacggccctgctg
cgctccgcgcccaccgcctaccgcacccgggtcaacgacgtcctgctcaccgcgctcgcc
ctggcactggcccgctggaccggccacgaccgcgtccgtctggacctggagggccacggc
cgggaggacctgctggacggcgtcgacctctcgcgcaccgtcgggtggttcaccaccgtc
taccccgtcgccctccaggtgtccgaccccggcgacctcggcccggaccgcgactggcgc
tccctggtgaagtcggtccgccgccagctgcgcgccgtgcccgccaacggcatcggctac
ggcgccctgcgcaccttcggaccgcccgaggtccgcgaacgcctcggcgcccaggcccac
agccaggtggtgttcaactacctcggccagtgggacgcacgccccgagacggcggacagc
ggcctcgtccgcgccgaacacggctccttcggacaggaccacgacccgcgcgaccccggc
tcgcacccggtggaggtggtgggcgcggtgcagcacggccgcctcgccttcacctggcac
caccggccgggcctgcacgacacggcgaccgtgcgccgggcggccgaggacttcgccgag
gccctgcgccacctcgcccggcacgcccggggaggccgatga
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