Streptomyces alboniger: CP975_09130
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Entry
CP975_09130 CDS
T06908
Symbol
murF
Name
(GenBank) UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase
KO
K01929
UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase [EC:
6.3.2.10
]
Organism
salw
Streptomyces alboniger
Pathway
salw00300
Lysine biosynthesis
salw00550
Peptidoglycan biosynthesis
salw01100
Metabolic pathways
salw01502
Vancomycin resistance
Brite
KEGG Orthology (KO) [BR:
salw00001
]
09100 Metabolism
09105 Amino acid metabolism
00300 Lysine biosynthesis
CP975_09130 (murF)
09107 Glycan biosynthesis and metabolism
00550 Peptidoglycan biosynthesis
CP975_09130 (murF)
09160 Human Diseases
09175 Drug resistance: antimicrobial
01502 Vancomycin resistance
CP975_09130 (murF)
Enzymes [BR:
salw01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.2 Acid-D-amino-acid ligases (peptide synthases)
6.3.2.10 UDP-N-acetylmuramoyl-tripeptide---D-alanyl-D-alanine ligase
CP975_09130 (murF)
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Motif
Pfam:
Mur_ligase_M
Mur_ligase_C
Mur_ligase
DUF561
DUF2126
DHHA1
Motif
Other DBs
NCBI-ProteinID:
QEV17647
UniProt:
A0A5J6HKE9
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All DBs
Position
complement(2065262..2066677)
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AA seq
471 aa
AA seq
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MIALSLAEIATVVGGQTYDIPDPAIQVTGPVVRDSREVEPGSLFVAFVGERVDGHDYAAD
VVAAGAAAVLASRPVGVPAIVVDDVQAALGALARHVVERLGATLVALTGSVGKTSSKDLL
AQVLRRKAPTVFTPGSLNNEIGLPLTALSATDDTRFLVLEMGARGIGHIRYLAGLTPPKI
GLVLNVGTAHIGEFGGREQIAQAKGELVEALPEDGAAVLNADDPLVRAMASRTKARVLLF
GEAEDADVRAENVRLTKNGQPAFTLHTPSGCSDVTLRLYGEHHVSNALAAAAVAHELGMS
VDEIALALSEAGTLSRWRMEVTERPDGVTVVNDAYNANPESMRAALRALAAMGKGRRTWA
VLGQMAELGDESLTEHDAVGRLAVRLNVSKLVAVGGREASWLQLGAYNEGSWGEESVHVS
DAQAAIDLLRSELRAGDVVLVKASRSVGLERVATALLDDAAVSSEGQVSGR
NT seq
1416 nt
NT seq
+upstream
nt +downstream
nt
gtgatcgccctctccctcgccgagatcgccaccgtcgtcggcgggcagacgtacgacata
ccggatccggccatccaggtcaccggacccgtcgtccgggactcccgtgaggtggagccc
ggcagcctcttcgtcgccttcgtcggcgagcgcgtcgacggccacgactacgcggcggac
gtcgtcgcggcgggtgccgcggccgtcctcgcgtcgcggcccgtcggggtgcccgccatc
gtcgtcgacgacgtacaggcggcgctcggcgcccttgcacggcacgtcgtcgagcgcctc
ggcgccacgttggtggcactgaccggctcggtcggcaagaccagctccaaggacctgctc
gcccaggtgctgcgccgcaaggcgcccacggtcttcacgccgggctccctcaacaacgag
atcggcctgccgctgaccgcgctcagcgccaccgacgacacgaggttcctcgtcctggag
atgggggcgcgcggaatcggccatatccggtacctcgccgggctcacgccgccgaagatc
ggcctcgtcctgaacgtcggcaccgcccacatcggcgagttcggcggccgcgagcagatc
gcacaagcgaagggcgagctggtcgaggcgctgcccgaggacggcgccgcggtcctcaac
gccgacgacccgctcgtacgcgccatggcgtcgcgtacgaaggcgcgcgtgctgctcttc
ggagaggccgaggacgccgacgtacgtgccgagaatgtccgtctcacgaagaacggacag
cctgcttttacgctgcacacaccctccgggtgcagcgacgtgaccttgcggctgtacggt
gagcaccacgtgtcgaacgcgcttgccgcggccgccgtcgcccatgagctgggcatgtcc
gtcgacgagatcgccctcgcgctctccgaggcgggcacgctgtcccgctggcggatggag
gtcaccgagcgcccggacggtgtgacggtcgtcaacgacgcctacaacgcgaaccccgag
tccatgcgagccgctctgcgcgcgctcgcggccatgggcaaggggcgcaggacgtgggcg
gtgctcggtcagatggccgagctgggggacgagagtctcaccgagcacgacgcggtcgga
cgccttgccgtccggctcaacgtgagcaagctcgtggcagtcgggggcagggaagcgtcc
tggctccaactgggcgcatacaacgagggttcgtggggtgaggagtcggtgcacgtgtcc
gacgcacaggcggcgatcgacctgctgcgcagcgagctgcgcgcgggagacgtcgtactg
gtgaaggcgtccagatcggtcggtctcgagcgggtcgccacggcgctgctcgacgacgcc
gcggtgtcttctgaggggcaggtctccggccgatga
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