KEGG   Streptomyces alboniger: CP975_33840
Entry
CP975_33840       CDS       T06908                                 
Name
(GenBank) 2-isopropylmalate synthase
  KO
K01649  2-isopropylmalate synthase [EC:2.3.3.13]
Organism
salw  Streptomyces alboniger
Pathway
salw00290  Valine, leucine and isoleucine biosynthesis
salw00620  Pyruvate metabolism
salw01100  Metabolic pathways
salw01110  Biosynthesis of secondary metabolites
salw01210  2-Oxocarboxylic acid metabolism
salw01230  Biosynthesis of amino acids
Module
salw_M00432  Leucine biosynthesis, 2-oxoisovalerate => 2-oxoisocaproate
Brite
KEGG Orthology (KO) [BR:salw00001]
 09100 Metabolism
  09101 Carbohydrate metabolism
   00620 Pyruvate metabolism
    CP975_33840
  09105 Amino acid metabolism
   00290 Valine, leucine and isoleucine biosynthesis
    CP975_33840
Enzymes [BR:salw01000]
 2. Transferases
  2.3  Acyltransferases
   2.3.3  Acyl groups converted into alkyl groups on transfer
    2.3.3.13  2-isopropylmalate synthase
     CP975_33840
SSDB
Motif
Pfam: HMGL-like IPMS_D2 LeuA_dimer Nuc_deoxyri_tr2
Other DBs
NCBI-ProteinID: QEV21843
UniProt: A0A5J6HTT8
LinkDB
Position
7730123..7731931
AA seq 602 aa
MTATPSPLPVPPRITTPAGPRGADQPWWNTQLGSAMPFARYERSGTRRPRPLPLTDRTWP
SKSLVRAPLWASVDLRDGNQALRDPMDTRRKRAMFDLLVRMGFKDIEVGYPSASEADFSF
VRTLIEEDLIPDDVTISVFAPARPELIDRTFEAIDGVDRAVVHLCHATACLWREVVFAMT
PGEVEEMAVRAAEHVARRTDATKGTRLRFQYSPETFNVTEPEFVLRLSNTVAALWDASPD
RPVTLNLPTTVETDSPHVFADQVEWMHRNLHNRRSVILSVHPHNDRGTAVASAELAVMAG
AERIEGTLFGNGERTGNVCLATLALNLFSQGVDPQLDFSDIDGIRRTVEFANQLPVPPRH
PYAGDLVHTAFSGTHQDAIAKGLAAMGRRAAEADTPAAAVPWDVPYLPIDPRDVGRTYES
VVRVNSQSGRGGVAHVLNTAYGLDLPRTMRVEFGRRVQRAADHGGGELTSHELHALFTEE
YLEFDRPRLMLKEFRTTPGAAGVTLAALVVLADGAERRLAADGPDAATAFAAALADIGIT
VRRPELTCHPLPDTVGTRFAAYARVTVDGTAQHGAAVTEDAELARLTAVTSAVNRAVEHR
VP
NT seq 1809 nt   +upstreamnt  +downstreamnt
atgaccgcaaccccgtcgcccctgcccgtcccaccccggatcaccacgcccgcgggaccg
cgcggagcggatcagccgtggtggaacacccagctgggctcggccatgcccttcgcccgc
tacgagcggtccggcacacggcgtccgcgtccgcttccgctgacggaccgcacctggccc
tcgaagtccttggtcagggccccgctgtgggcgtcggtggacctcagggacggcaaccag
gcgctgcgcgacccgatggacacaagacggaagagagcgatgttcgacctgctcgtccgc
atgggcttcaaggacatcgaggtcggatacccctcggccagcgaagcggacttctcgttc
gtccgcacgctgatcgaggaggacctcatcccggacgacgtgacgatatccgtcttcgca
ccggccaggcccgaactgatcgaccggaccttcgaggccatcgacggggtggaccgggcg
gtggtgcatctgtgccacgccaccgcctgcctgtggcgcgaggtggtcttcgcgatgacc
cccggcgaggtcgaggagatggcggtccgggcagcggagcacgtcgcccggcgcacggac
gccaccaagggaacccggctgcgtttccagtactcaccggagacgttcaacgtgacggag
ccggagttcgtcctgcgcctgtcgaacaccgtcgccgcgctgtgggacgcgagtccggac
cgcccggtcaccctcaatctgccgaccacggtggagaccgactccccccacgtgttcgcc
gaccaggtcgagtggatgcaccgcaacctgcacaaccggcggtcggtcatcctctccgtc
catccgcacaacgaccgcggcaccgcggtcgcctccgcggaactggccgtcatggcgggc
gccgagcggatcgagggcacgctcttcggcaacggggaacgcacgggcaacgtctgtctc
gcgacactggcgctgaacctcttcagccagggagtcgacccccagctggacttctcggac
atcgacgggatccgccgcacggtcgagttcgccaaccagctaccggtgccgccccgtcac
ccgtacgccggcgacctcgtccacacggccttctccggcacgcaccaggacgccatagcc
aagggcctggccgcgatgggacgccgagccgccgaagcggacacgcccgccgccgcggtg
ccctgggacgtcccgtacctgcccatcgatccgagggacgtgggccggacgtacgagtcc
gtcgtgcgggtcaacagccagtccggcaggggcggggtggcgcatgtgctcaacaccgcg
tacgggctggacctgccgcgcacgatgcgggtggagttcggccgccgtgtccagcgtgcc
gcggaccacggcggcggcgaactcacctcgcacgaactgcacgccctcttcaccgaggag
tacctggagttcgaccggccgcggctcatgctcaaggagttccggacgacgcccggcgcc
gccggtgtcaccctcgccgccctggtcgtcctcgcggacggcgcggagcggcgcctggcc
gccgacggaccggacgcggccaccgccttcgccgcggccctggcggacatcggcatcacc
gtgcggcgaccggaactgacctgccacccgctgcccgacaccgtcggcacccgcttcgcc
gcgtacgcgcgggtcaccgtcgacggcacggcccagcacggcgccgccgttaccgaggac
gcggaactggcccggttgacggcggtgacctccgcggtcaaccgggcggttgagcaccgc
gttccatga

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