Streptomyces ambofaciens: SAM23877_2179
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Entry
SAM23877_2179 CDS
T04055
Symbol
murF
Name
(GenBank) UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alan ine ligase
KO
K01929
UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase [EC:
6.3.2.10
]
Organism
samb
Streptomyces ambofaciens
Pathway
samb00300
Lysine biosynthesis
samb00550
Peptidoglycan biosynthesis
samb01100
Metabolic pathways
samb01502
Vancomycin resistance
Brite
KEGG Orthology (KO) [BR:
samb00001
]
09100 Metabolism
09105 Amino acid metabolism
00300 Lysine biosynthesis
SAM23877_2179 (murF)
09107 Glycan biosynthesis and metabolism
00550 Peptidoglycan biosynthesis
SAM23877_2179 (murF)
09160 Human Diseases
09175 Drug resistance: antimicrobial
01502 Vancomycin resistance
SAM23877_2179 (murF)
Enzymes [BR:
samb01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.2 Acid-D-amino-acid ligases (peptide synthases)
6.3.2.10 UDP-N-acetylmuramoyl-tripeptide---D-alanyl-D-alanine ligase
SAM23877_2179 (murF)
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Motif
Pfam:
Mur_ligase_M
Mur_ligase_C
Mur_ligase
DUF561
Motif
Other DBs
NCBI-ProteinID:
AKZ55228
UniProt:
A0A0K2AQE7
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Position
complement(2267038..2268468)
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AA seq
476 aa
AA seq
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MIALSLAEIAEVVGGRMHDIPDASVQVTGPVVRDSREAGPGSLFVAFVGERVDGHDYAPS
VVEAGAVAVLGSRPVGVPAIVVDDVQTALGALARHVVRRLGTTLVALTGSAGKTSTKDLI
AQVLRRKAPTVFTPGSMNNEVGLPLTALTATDETRFLVLEMGARGIGHIRYLTELTPPKV
GLVLNVGSAHIGEFGGREQIAQAKGELVEALPPAEEGGAAILNADDPLVRAMASRTKAKV
ILFGESDEADVRGENVRLTDSGQPSFRLHTPSGASDVTMRLYGEHHVSNALAAAAVAHEL
GMSADEIATALSEAGSLSRWRMEVTERPDGVTVVNDAYNANPESMKAALRALVAMGKAAQ
AKGGRTWAVLGKMAELGDEALAEHDAVGRLAVRLNVSKLVAVGGREAQWLQLGAYNEGSW
GEESVHVSDAQAAVDLLRSELRPGDVVLVKASRSVGLERVATALLETGAEGEVAAR
NT seq
1431 nt
NT seq
+upstream
nt +downstream
nt
gtgatcgccctctctctcgccgagatcgcagaagtcgtcggcgggcggatgcatgacata
ccggacgcgtccgtgcaggtcaccgggccggtcgtccgggactcgcgggaagcggggccc
ggcagcctgttcgtcgccttcgtcggcgagcgggtggacggccacgactacgcgccgtcg
gtcgtcgaggcgggcgcggtggccgtgctcggctcccggcccgtcggcgtgcccgcgatc
gtcgtggacgacgtacagaccgccctcggggccctcgcccggcatgtcgtacggcgcctc
ggcaccaccctcgtggccctcaccgggtccgccggcaagaccagcaccaaggacctcatc
gcccaggtgctgcgccgcaaggcgcccacggtgttcacgccgggctccatgaacaacgag
gtcgggctgccgctcaccgcgctcaccgccaccgacgagacgaggttcctcgtcctggag
atgggcgcccgcggcatcggccacatccgctacctcaccgaactcaccccgccgaaggtc
ggcctcgtcctcaacgtcggctccgcgcacatcggcgagttcggcggccgggagcagatc
gcccaggccaagggcgaactcgtcgaggcgctgccgccggccgaggagggcggtgccgcg
atcctcaacgcggacgacccgctcgtacgggccatggcctcccgaacgaaggcgaaggtg
atccttttcggagagtccgacgaagcggacgttcgcggtgagaacgtgcgactcacggac
agcggacagccctcgttcaggcttcacacaccctccggtgcaagcgatgtgaccatgcgc
ctgtacggtgagcaccacgtgtcgaacgcgctcgccgcggccgccgtcgcccacgagttg
ggcatgtccgcagacgagatcgccaccgcgctctccgaggcgggctccctctcccgctgg
cggatggaggtcaccgagcgcccggacggcgtgacggtcgtcaacgacgcctacaacgcg
aaccccgagtcgatgaaggccgcgctgcgtgcgctggtcgccatgggcaaagccgcacag
gcgaaggggggccgtacgtgggcggtgctcggcaagatggccgagctcggggacgaggcg
ctcgccgagcacgacgcggtcggacggctcgccgtccggctcaacgtcagcaagctcgtc
gcggtcgggggcagggaagcccaatggctgcaactgggcgcatataacgagggttcgtgg
ggtgaggagtcggtgcacgtgtccgacgcacaggcggcggtcgacctgttgcgcagcgag
ttgcgcccgggagacgtcgtactcgtgaaggcgtcccgttcggtgggtctggagcgcgtc
gccacggcgctgctggagaccggcgccgagggtgaggtcgccgcccgatga
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