KEGG   Streptomyces ambofaciens: SAM23877_2578
Entry
SAM23877_2578     CDS       T04055                                 
Symbol
leuA
Name
(GenBank) 2-isopropylmalate synthase
  KO
K01649  2-isopropylmalate synthase [EC:2.3.3.13]
Organism
samb  Streptomyces ambofaciens
Pathway
samb00290  Valine, leucine and isoleucine biosynthesis
samb00620  Pyruvate metabolism
samb01100  Metabolic pathways
samb01110  Biosynthesis of secondary metabolites
samb01210  2-Oxocarboxylic acid metabolism
samb01230  Biosynthesis of amino acids
Module
samb_M00432  Leucine biosynthesis, 2-oxoisovalerate => 2-oxoisocaproate
Brite
KEGG Orthology (KO) [BR:samb00001]
 09100 Metabolism
  09101 Carbohydrate metabolism
   00620 Pyruvate metabolism
    SAM23877_2578 (leuA)
  09105 Amino acid metabolism
   00290 Valine, leucine and isoleucine biosynthesis
    SAM23877_2578 (leuA)
Enzymes [BR:samb01000]
 2. Transferases
  2.3  Acyltransferases
   2.3.3  Acyl groups converted into alkyl groups on transfer
    2.3.3.13  2-isopropylmalate synthase
     SAM23877_2578 (leuA)
SSDB
Motif
Pfam: HMGL-like IPMS_D2 LeuA_dimer
Other DBs
NCBI-ProteinID: AKZ55627
UniProt: A0A0K2AS42
LinkDB
Position
complement(2697455..2699176)
AA seq 573 aa
MANRQQPSSMPITKYRGYEQVDIPDRTWPHQRITTAPRWLSTDLRDGNQALIDPMSPARK
RAMFDLLVKMGYKEIEVGFPASGQTDFDFVRSIIEDPDAIPEDVTISVLTQAREDLIERT
VESLKGARRATVHLYNATAPVFRRVVFRGSRDDIKQIAVDGTRLVMEYAEKLLGPETEFG
YQYSPEIFTDTELDFALEVCEAVMDTYQPGPGREIILNLPATVERSTPSTHADRFEWMGR
NLSRREYVCLSVHPHNDRGTAVAAAELALMAGADRVEGCLFGQGERTGNVDLVTLGMNLF
SQGVDPQIDFSDIDEIRRTWEYCNQMEVHPRHPYVGDLVYTSFSGSHQDAIKKGFDAMEA
EAAAKGVTVDDIEWAVPYLPIDPKDVGRSYEAVIRVNSQSGKGGIAYVLKNDHKLDLPRR
MQIEFSKLIQAKTDAEGGEITPTAIWDVFQDEYLPNPDNPWGRIQVANGQTTTDRDGIDT
LTVEATVDGQETTLVGTGNGPISAFFHALQGVGIDVRLLDYQEHTMSEGASAQAASYIEC
AIGDKVLWGIGIDANTTRASLKAVVSAVNRAAR
NT seq 1722 nt   +upstreamnt  +downstreamnt
atggccaaccgccagcagcccagttccatgccgatcaccaagtaccgcggctacgagcag
gtcgacatccccgaccgcacctggccccaccagcgcatcaccaccgccccccgctggctc
tccaccgacctgcgcgacggcaaccaggcactgatcgaccccatgtcgcccgcccgcaag
cgcgcgatgttcgacctgctggtcaagatgggctacaaggagatcgaggtcggcttcccc
gcctccggccagaccgacttcgacttcgtacgctcgatcatcgaggacccggacgccatc
ccggaggacgtgacgatctccgtgctgacgcaggcccgtgaggacctgatcgagcgcacg
gtggagtccctgaagggcgccaggcgggccaccgtccacctgtacaacgcgaccgccccg
gtcttccgccgggtcgtcttccgcggctcccgggacgacatcaagcagatcgccgtcgac
ggcacccggctggtcatggagtacgccgagaagctgctgggccccgagacggagttcggc
taccagtacagccccgagatcttcaccgacaccgagctggacttcgccctggaggtctgc
gaggcggtgatggacacctaccagcccggccccggccgcgagatcattctcaacctgccg
gccaccgtggagcgttcgacgccgtccacgcacgccgaccgcttcgagtggatgggccgc
aacctctcccgccgcgagtacgtctgcctgtccgtccacccgcacaacgaccgcggtacg
gcggtggcggcggccgagctggcgctgatggccggcgccgaccgcgtcgagggctgcctg
ttcggacagggcgagcgcaccggcaacgtcgacctggtcaccctgggcatgaacctgttc
tcgcagggggtcgacccgcagatcgacttctccgacatcgacgagatccgtcgcacgtgg
gagtactgcaaccagatggaggtccacccgcgccacccgtacgtgggcgacctggtctac
acgtccttctccggctcccaccaggacgccatcaagaagggcttcgacgccatggaggcc
gaggcggccgccaagggcgtcaccgtcgacgacatcgagtgggccgtgccctacctgccg
atcgaccccaaggacgtcggccgctcctacgaggcggtcatccgcgtcaactcgcagtcc
ggcaagggcggcatcgcgtacgtcctgaagaacgaccacaagctggacctgccgcgccgg
atgcagatcgagttctccaagctgatccaggccaagacggacgccgagggcggcgagatc
acgcccacggccatctgggacgtcttccaggacgagtacctgcccaacccggacaacccc
tggggccgcatccaggtcgccaacggccagaccaccaccgaccgcgacggcatcgacacc
ctcaccgtcgaggccacggtcgacggccaggagaccacgctggtcggcaccggcaacgga
ccgatctcggcgttcttccacgccctgcagggcgtcggcatcgacgtacgcctgctggac
taccaggagcacacgatgagcgagggcgcctccgcgcaggccgcctcctacatcgagtgc
gccatcggcgacaaggtgctgtggggcatcggaatcgacgcgaacaccacgcgcgcctcg
ctgaaggcggtcgtctccgccgtcaaccgagcggcgcgctga

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