Streptomyces ambofaciens: SAM23877_4216
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Entry
SAM23877_4216 CDS
T04055
Symbol
ilvD
Name
(GenBank) dihydroxyacid dehydratase
KO
K01687
dihydroxy-acid dehydratase [EC:
4.2.1.9
]
Organism
samb
Streptomyces ambofaciens
Pathway
samb00290
Valine, leucine and isoleucine biosynthesis
samb00770
Pantothenate and CoA biosynthesis
samb01100
Metabolic pathways
samb01110
Biosynthesis of secondary metabolites
samb01210
2-Oxocarboxylic acid metabolism
samb01230
Biosynthesis of amino acids
Module
samb_M00019
Valine/isoleucine biosynthesis, pyruvate => valine / 2-oxobutanoate => isoleucine
samb_M00570
Isoleucine biosynthesis, threonine => 2-oxobutanoate => isoleucine
Brite
KEGG Orthology (KO) [BR:
samb00001
]
09100 Metabolism
09105 Amino acid metabolism
00290 Valine, leucine and isoleucine biosynthesis
SAM23877_4216 (ilvD)
09108 Metabolism of cofactors and vitamins
00770 Pantothenate and CoA biosynthesis
SAM23877_4216 (ilvD)
Enzymes [BR:
samb01000
]
4. Lyases
4.2 Carbon-oxygen lyases
4.2.1 Hydro-lyases
4.2.1.9 dihydroxy-acid dehydratase
SAM23877_4216 (ilvD)
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Ortholog
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Motif
Pfam:
ILVD_EDD_N
ILV_EDD_C
DUF4154
Motif
Other DBs
NCBI-ProteinID:
AKZ57261
UniProt:
A0A0K2AWI5
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Position
4475353..4477206
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AA seq
617 aa
AA seq
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MPELRSRTVTHGRNMAGARALMRASGVPGADIGRKPIIAVANSFTEFVPGHTHLAPVGRI
VSEAVVAAGGIPREFNTIAVDDGIAMGHGGMLYSLPSRDLIADSVEYMVEAHCADALICI
SNCDKITPGMLNAALRLNIPTVFVSGGPMESGRATLVDGTVRTLDLVDAMSEAVNDKISD
EDILRIEENACPTCGSCSGMFTANSMNCLTEAIGLSLPGNGSVLATHTARKALYENAART
VLDLTRRYYEQDDDSVLPRNIATPAAFGNAMALDIAMGGSTNTILHLLAAAQEAEVSFGL
TEMDALSRRVPCLAKVAPNVAKDRTYYMEDVHRAGGIPALLGELHRGGLLNEDVHSVHSP
SLADWLKTWDVRGGSPSQEAVELWHAAPGCVRSAEAFSQSERWDSLDEDAEGGCIRSVEH
AYSKDGGLAVLRGNLAVDGCVVKTAGVDESIWTFEGPAVVCESQEEAVEKILTQQVKEGD
VVVIRYEGPKGGPGMQEMLYPTSYLKGRGLGKTCALVTDGRFSGGTSGLSIGHASPEAAA
GGTIALVEDGDRVRIDIPNRSIELLVDDAELARREQALNGRYAPRKRDRKVSAALKAYAA
MATSADKGAVRDVSRLG
NT seq
1854 nt
NT seq
+upstream
nt +downstream
nt
atgcccgagctgaggtcccgcacagtcacccacggccgcaacatggcgggcgcccgcgcc
ctgatgcgtgcctccggtgtacccggcgcggacatcggccggaagccgatcatcgccgtc
gccaacagcttcacggagttcgtgccgggccacacccacctcgccccggtcggccggatc
gtcagcgaggcggtcgtggcggccggcggcatcccgcgcgagttcaacacgatcgccgtc
gacgacggcatcgccatgggccacggcggcatgctctactccctgccctcccgcgacctg
atcgcggacagcgtggagtacatggtcgaggcccactgcgccgacgcgctgatctgcatc
tccaactgcgacaagatcaccccgggcatgctcaacgcggcgctccgcctgaacatcccc
acggtcttcgtctccggcggccccatggagtccggccgcgccaccctggtcgacggcacc
gtccgcaccctggacctggtcgacgcgatgtcggaggcggtcaacgacaagatctccgac
gaggacatcctccgcatcgaggagaacgcctgcccgacctgcggctcgtgttccggcatg
ttcaccgccaactcgatgaactgcctcaccgaggccatcggcctctccctccccggcaac
ggctcggtcctggccacccacaccgcccgcaaggcgctctacgagaacgccgcccgcacg
gtgctggacctgacccgccgctactacgagcaggacgacgactcggtcctgccccgcaac
atcgccacccccgcggccttcggcaacgccatggccctggacatcgcgatgggcggctcg
accaacacgatcctgcacctgctggccgccgcgcaggaggcggaggtctccttcggcctc
accgagatggacgccctctcgcgccgcgtcccgtgcctcgccaaggtcgcgcccaacgtc
gccaaggaccgcacgtactacatggaggacgtgcaccgcgccggcggcatccccgccctc
ctcggcgaactgcaccgcggcggcctgctcaacgaggacgtgcactccgtccacagcccg
tccctggccgactggctgaagacctgggacgtgcgcggcggctccccgtcgcaggaggcg
gtcgagctgtggcacgccgctcccgggtgtgtgcggtcggcggaggccttctcccagtcc
gagcgctgggactccctggacgaggacgccgagggcggctgcatccgctccgtcgagcac
gcctactccaaggacggcggcctcgccgtcctgcgcggcaacctcgccgtcgacggctgc
gtcgtgaagacggcgggcgtcgacgagtccatctggaccttcgagggcccggcggtcgtc
tgcgagtcgcaggaggaggccgtcgagaagatcctcacccagcaggtcaaggagggcgac
gtcgtcgtcatccgctacgagggccccaagggcggccccggcatgcaggagatgctctac
cccacctcgtacctgaagggccgcggcctcgggaagacctgcgccctggtcaccgacggc
cgcttctccggcggcacctcgggcctgtccatcggccacgcctcgccggaggcggccgcc
ggcggcaccatcgccctcgtcgaggacggcgaccgcgtccgcatcgacatcccgaaccgc
tccatcgagctgctggtcgacgacgccgaactggcccgccgcgagcaggccctgaacggc
aggtacgccccgaggaagcgcgaccgcaaggtctccgcggccctgaaggcgtacgcggcc
atggcgaccagcgccgacaagggcgcggtgcgggacgtgagcaggctgggctga
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