Streptomyces ambofaciens: SAM23877_5305
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Entry
SAM23877_5305 CDS
T04055
Symbol
leuC
Name
(GenBank) 3-isopropylmalate isomerase subunit, dehydratase component
KO
K01703
3-isopropylmalate/(R)-2-methylmalate dehydratase large subunit [EC:
4.2.1.33
4.2.1.35
]
Organism
samb
Streptomyces ambofaciens
Pathway
samb00290
Valine, leucine and isoleucine biosynthesis
samb00660
C5-Branched dibasic acid metabolism
samb01100
Metabolic pathways
samb01110
Biosynthesis of secondary metabolites
samb01210
2-Oxocarboxylic acid metabolism
samb01230
Biosynthesis of amino acids
Module
samb_M00432
Leucine biosynthesis, 2-oxoisovalerate => 2-oxoisocaproate
Brite
KEGG Orthology (KO) [BR:
samb00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00660 C5-Branched dibasic acid metabolism
SAM23877_5305 (leuC)
09105 Amino acid metabolism
00290 Valine, leucine and isoleucine biosynthesis
SAM23877_5305 (leuC)
Enzymes [BR:
samb01000
]
4. Lyases
4.2 Carbon-oxygen lyases
4.2.1 Hydro-lyases
4.2.1.33 3-isopropylmalate dehydratase
SAM23877_5305 (leuC)
4.2.1.35 (R)-2-methylmalate dehydratase
SAM23877_5305 (leuC)
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Paralog
GFIT
Motif
Pfam:
Aconitase
DUF4946
Motif
Other DBs
NCBI-ProteinID:
AKZ58350
UniProt:
A0A0K2AYY3
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All DBs
Position
5639100..5640530
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AA seq
476 aa
AA seq
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MGRTLAEKVWDDHVVRRAEGEPDLLFIDLHLLHEVTSPQAFDGLRKSGRPVRRLDLTIAT
EDHNTPTLDIDKPIADPVSRVQLETLRKNCADFGVRLHPLGDVEQGVVHVVGPQLGLTQP
GTTVVCGDSHTSTHGAFGALAFGIGTSQVEHVLATQTLPMVRPKTMAITVNGALPDGVTA
KDLILAIIAKIGTGGGQGYVLEYRGEAIEKLSMEARMTICNMSIEAGARAGMIAPDETTF
AYLQGRPHAPEGADWDAAVEYWKTLRTDDDAEFDAEVVIEAAELSPFVTWGTNPGQGAPL
SAAVPDPASYEDASERFAAEKALEYMGLEAGQPLRSIKVDTVFVGSCTNGRIEDLRAAAE
IVRDRKVADGVRMLVVPGSARVGLQAVSEGLDVVFKEAGAEWRHAGCSMCLGMNPDQLAP
GERSASTSNRNFEGRQGKGGRTHLVSPQVAAATAVLGHLASPADLSAADVPTPAGV
NT seq
1431 nt
NT seq
+upstream
nt +downstream
nt
atgggtaggacactcgcggagaaggtctgggacgaccacgtcgtccggcgcgccgagggc
gagcccgacctcctcttcatcgatctgcacctgctgcacgaggtgaccagcccgcaggcc
ttcgacggcctccgcaagagcggccgcccggtgcgccggctcgacctgaccatcgccacc
gaggaccacaacaccccgacgctcgacatcgacaagcccatcgcggacccggtctcccgg
gtccagctggagacgctgcgcaagaactgcgcggacttcggcgtccggctgcacccgctg
ggcgacgtcgagcagggcgtcgtgcacgtcgtgggcccgcagctgggcctgacccagccc
ggcaccaccgtggtctgcggcgactcgcacacctccacgcacggcgcgttcggcgcgctg
gccttcggcatcggcacctcccaggtcgagcacgtgctggccacccagacgctgcccatg
gtccgcccgaagaccatggcgatcaccgtcaacggcgcgctgcccgacggtgtcacggcc
aaggacctcatcctggcgatcatcgccaagatcggcaccggcggcggccagggctacgtc
ctggaataccggggcgaggccatcgagaagctctcgatggaggcccgcatgaccatctgc
aacatgtcgatcgaggccggcgcccgcgcgggcatgatcgcccccgacgagaccaccttc
gcctacctccagggccgcccccacgcccccgagggcgccgactgggacgcggccgtcgag
tactggaagacgctgcgcacggacgacgacgccgagttcgacgccgaggtcgtcatcgag
gccgccgagctgtcgccgttcgtcacctggggcaccaacccggggcagggcgcaccgctg
tcggccgccgtccccgacccggcttcgtacgaggacgcttcggagcgcttcgccgccgaa
aaggccctggagtacatgggcttggaggccggacagccgctgcgctccatcaaggtggac
accgtcttcgtaggttcctgcaccaacggccgcatcgaggacctgcgcgccgccgccgag
atcgtgcgggaccgcaaagtcgccgacggcgtacggatgctggtcgtccccggctccgcg
cgggtgggcctgcaggccgtctccgagggcctggacgtggtcttcaaggaggccggggcc
gaatggcggcacgcgggctgctcgatgtgcctgggcatgaacccggaccagctcgccccc
ggtgagcgctccgcgtccacctccaaccgcaacttcgagggacggcagggcaagggcggc
cgcacccacctggtgtcgccgcaggtcgcggccgcgacggcggtcctgggccacctggcc
tccccggccgacctgtccgccgccgacgtccccacgcccgctggagtctga
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