Sandaracinus amylolyticus: DB32_004446
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Entry
DB32_004446 CDS
T03935
Name
(GenBank) UDP-N-acetylmuramoylalanyl-D-glutamyl-2,6-diaminopimelate--D-alanyl-D-alanine ligase
KO
K01929
UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase [EC:
6.3.2.10
]
Organism
samy
Sandaracinus amylolyticus
Pathway
samy00300
Lysine biosynthesis
samy00550
Peptidoglycan biosynthesis
samy01100
Metabolic pathways
samy01502
Vancomycin resistance
Brite
KEGG Orthology (KO) [BR:
samy00001
]
09100 Metabolism
09105 Amino acid metabolism
00300 Lysine biosynthesis
DB32_004446
09107 Glycan biosynthesis and metabolism
00550 Peptidoglycan biosynthesis
DB32_004446
09160 Human Diseases
09175 Drug resistance: antimicrobial
01502 Vancomycin resistance
DB32_004446
Enzymes [BR:
samy01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.2 Acid-D-amino-acid ligases (peptide synthases)
6.3.2.10 UDP-N-acetylmuramoyl-tripeptide---D-alanyl-D-alanine ligase
DB32_004446
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Gene cluster
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Motif
Pfam:
Mur_ligase_M
Mur_ligase_C
Mur_ligase
TPP_enzyme_N
Desulfoferrod_N
Motif
Other DBs
NCBI-ProteinID:
AKF07297
UniProt:
A0A0F6YIR8
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Position
5131087..5132580
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AA seq
497 aa
AA seq
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MATPIPANSARFSIDELAVATRGTVAASTDRPLVGVVTDSRAVTPGCIFVALRGAKHDAH
DFVPAVIAAGAGALVVSQPVSAPPGVAVVIVPDTLRALGDLAHAHRRRFPVALVAVTGSV
GKTTTKELTAAGLEALGLRVLRSAGNLNNRIGVPMTLLTLGADDDVAVIEMGMNVPGEIA
RLTEIAMPSVGVVTAVAEVHTEGVGGIEGVAREKGALLLGLGADAAAVFTADDGILAPYA
ERSPARTKLSFGLAEGSDVRVADVQIALDGTRCIYVVQGLNEFVNAKLALIGEGPARCGA
AALAAIVALRGADAVPAALEGIQRVAPGEGRARPIHGVGGTVILDDAYNASPRSTELALR
TCYELARARGGRAIAVLGDMLELGVESERLHESVGEAAVASGIALLVCCGPEMRAAARGA
LTAGMASGVSGIRIERLDDPTEAISLVRAFVEPNDVILVKGSRSMRMERVVEGLREVDAF
GSTAPGIIAPGSEEAPR
NT seq
1494 nt
NT seq
+upstream
nt +downstream
nt
atggccacgccgattcccgcgaactccgcgcgattctcgatcgacgagctcgccgtcgcg
acgcgcggcaccgtcgccgcgagcaccgatcgcccgctcgtcggcgtcgtcaccgactct
cgcgccgtcacgcccggatgcatcttcgtcgcgctgcgcggcgcgaagcacgacgcgcac
gacttcgtgcccgccgtcatcgccgcgggcgcgggcgcgctcgtcgtctcgcagccggtg
agcgcgccccccggcgtcgcggtggtgatcgtccccgacacgctccgcgcgctcggtgat
ctcgcgcatgcgcatcgccgtcgcttccccgtcgcgctcgtggccgtcaccggatcggtc
ggcaagacgacgaccaaggagctcaccgccgcgggcctcgaggcgctcggcctgcgcgtg
ctgcgcagcgcgggcaacctcaacaaccgcatcggcgtgcccatgaccctgctgacgctc
ggcgccgatgacgacgtcgcggtgatcgagatgggcatgaacgtgcccggcgagatcgcg
cggctcaccgagatcgcgatgccgagcgtcggcgtcgtcaccgcggtcgccgaggtgcac
accgagggcgtgggcggcatcgagggcgtcgcgcgcgagaagggcgcgctcctgctcggg
ctcggcgccgacgcggcggccgtgttcaccgcggacgacgggatcctcgcgccctacgcc
gagcgcagccccgcgcgcacgaagctctcgttcgggctcgcagagggatcggacgtgcgc
gtcgcggacgtccagatcgcgctcgacggaacgcgctgcatctacgtcgtgcagggcctc
aacgagttcgtgaacgcgaagctcgcgctgatcggcgaaggtcccgcgcgctgcggcgcg
gccgcgctcgccgcgatcgtcgcgctccgcggcgccgacgcggtgcccgcggcgctcgag
ggcatccagcgcgtcgcgcccggcgaaggccgcgcgcgtccgatccacggcgtgggcggc
accgtcatcctcgacgacgcctacaacgcgagcccgcgctcgaccgagctcgcgctgcgc
acctgctacgagctcgcgcgcgctcgcggcgggcgcgcgatcgcggtgctcggcgacatg
ctcgagctcggcgtcgagagcgagcgcctgcacgagagcgtcggtgaagcggcggtcgcg
agcggcatcgcgctgctcgtctgctgcggccccgagatgcgcgcggccgcgcgcggcgcg
ctcaccgcgggcatggcgagcggcgtgagcggcatccgcatcgagcgcctcgacgatccc
accgaggcgatctcgctggtgcgcgcgttcgtcgagccgaacgacgtcatcctcgtgaag
ggatcgcgctcgatgcgcatggagcgcgtggtcgaagggctgcgcgaagtggacgcgttc
ggaagcaccgcgcccggcatcatcgcccccggcagtgaagaggcgccgcgatga
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