Sinocyclocheilus anshuiensis: 107668197 Help Entry 107668197         CDS       T04917                                  Name (RefSeq) ryanodine receptor 3-like   KO K04963   ryanodine receptor 3 Organism sanh  Sinocyclocheilus anshuiensis Pathway sanh04020   Calcium signaling pathway sanh04371   Apelin signaling pathway Brite KEGG Orthology (KO) [BR:sanh00001]  09130 Environmental Information Processing   09132 Signal transduction    04371 Apelin signaling pathway     107668197    04020 Calcium signaling pathway     107668197  09180 Brite Hierarchies   09183 Protein families: signaling and cellular processes    04040 Ion channels [BR:sanh04040]     107668197 Ion channels [BR:sanh04040]  Voltage-gated cation channels   Ryanodine receptor    107668197 BRITE hierarchy SSDB OrthologParalogGFIT Motif Pfam:  RYDR_Jsol RyR RYDR_ITPR RR_TM4-6 SPRY Ins145_P3_rec MIR RIH_assoc Ion_trans EF-hand_7 EF-hand_8 EF-hand_1 Ago_Mid EF-hand_6 Motif Other DBs NCBI-GeneID:  107668197 NCBI-ProteinID:  XP_016315475 LinkDB All DBs Position Unknown AA seq 4938 aa AA seqDB search MAEGGEGEDEVQFLRTDDEVVLQCVAAIQKENRKFCLSAEGLGNRLCYLEPTSEAKYFPP DLCICNFVLEQSLSVRALQEMLAGQNGEGAAQGGGHRTLLYGHAILLRHSFSGMYLTCLK TSRSLTDKLSFDVGLQEDSTGEACWWTIHPASKQRSEGEKVRIGDDLILVSVSSERYLHL SISNGSIQVDASFMQTLWNVQPTCSRSNLEVGFLLGGHVIRLFRGHDESLTIPESEQSQD QQRCILTGESFFLNCSWSGSHIRWGQPFRLRHLSTGYYLGQTEDHGLILLDKEKSDTTAT AFCFRPSKEKIDSGPKRDIDGMGVAEIKYGDSVCFIMHVSTGLWLSYLAPDAKSSRLGPP KRRAVLSPEGHMDDGLTLQLCQHEESRAARIIRNTTHLFTQFIRGLDGLNGEKTTEVTLP VCEVLQTLDDLIVYFQQPDSELEHEEKQRQLRSLIKRQDLFKEEGMLTLVSHCIDRLNVY NSAAEFEELAGEEAGEAWKDILNLLYELLATLIRGNRTNCTQFSRKLDWLVSKLERLESS SGILEVLHCILIESPESLNIIQKAHIKSIISLLYKHGRNHKILDVLCSLCVCNGVAVRAN QNFICDHLLPRRDLLLQTRLVNDVQSMRPNIFLGMSEGSAQYKKWYFELIIDQVDHYVTN EPTHLRVGWATTKGYAPYPGGGEGWGGNGVGDDLYSYGFDGLHLWSGRIPRAVASINQHL LNSDDVVSCCLDLGAPSMSFRINGQPVQGMFEDFNIDGFFFPVISFSAGVKVRFLLGGRH GDFKFLPPAGYAPCYEALLPKEKMRVEPVKEYKRDLEGVRDLLGTTEFLSQASFIPVPVD TSQIVLPPHLEHVRDKLAENIHELWGMNKIELGWMYGKVRDDNKRQHPCLVDFSKLPETE KNYNLQMSTETLKTLLALGCHVAQVNMNAEDDLKKMKLPKNYMMANGYKPTPLDLSDVKL TPGQEVLVDKLAENAHNVWAKDRIKQGWTYGIQQDLKNRRNPRLVPYALLDERTKKSNRD SLREAIRTLVGYGYFIDPPDQETAHTVEKEGIESIRLFRVEKIYAVKTGKWYFEFEALTG GDMRVGWARPGCRPDKELGLDDQSFVFDGYRGRRVHMGSHFFGRTWNKGDVVGCMINMED KSMIFTLNGEILITNKGSELCFADFETEDGFIPVCSLGLSQIGRMNLGKAASSFKYYTMC GLQEGFEPFAVNMNREVTMWFSKRLPTFVNVPEDHPHIEVTRIDETVDTPPCLKVTHKTY GTQTSNDDMVCCRLSMPVEFHSGPRKTTDINEVIAEDQRAKKDDGGKTDYGSITKHFYSV RVFAGQDPSSVWVGWVTPDYHYYSKYFSLSTVRTVTVTLGDERGRVHESVRRSNCYMVCA GDVVSGSTGRSNTDLEIGCSIDLASGLVSFTANGRDLPTAYQVEPNTKLFPAVFVQPTSP NLFQFEFPKIPDAMPLSSAIFKSLQRNPEPQCPPRLDVQTLVSVLWSRMPNTFLSVETAR VSERHGWVVQCLEPLQMMAVHIPEENRCIDIMELSENEDLRQFHYHTLKLFCALCALGNT RIAHVLCSHFDQSQLLYTIDNQYLSGQLREGFYDVLISIHLETAKEAHLMMNNEFIIPVT DETRSIRLFPDDSKRHSLPGVGLSTSLAPRFNFTPPCFITPKRDQPLFSPQIPLGILKEK AISMLTEAVQGGGAHIRDPVGGSVEYQFVPILKLIGTLLIMGALTSEEVRTILLLIDPSV FEDSKEEEEQTAVAEQGAEKEEATSNEEKAVEAGEEESKEAKQPPKGLLEKSLPESVKRQ MCELLHYFCDCELKQRIEAIVAFSDDFVSKLQYNQKFRYNELMQALNMSAAVTAKKTREF RSPPQEQINMLLNFSAGDDCTCPEELQEELQGFHDDLRLHCGIPMEEEEEEQDTSLKGRL MSLVYKIKGRPQKTEEKPTEQEQAAPTNLKELISQTMVTWAQECKIQDPALVRSMFSLLR RQYDGIGELLRALRKSYTVSAKSVGDATNLLASLGQIRSLLSVRMGEEEGQLMIDGLGDI MNNKVFYQHPNLMRVLGMHETVMEVMVNVLGGDKNKEIAFPKMVASCCRFLCYFCRISRQ NQKAMFDHLSYLLENSSVGLACPAMRGSTPLDVAASSVMDNNSLALALEEPDLEKVVTYL AGCGLQNCPMLIARGYPDIGWNPIEGERYLSFLRFAVFVNGESVEENANVVVKLLIRRPE CFGPALRGEGGQGLLAAMKEAIKISEDPALDLPNLPEGSAPTVGEDEEEEEVAHMGNSIM SFYSALIDLLGRCAPEMHLINKGKGEALRIRAILRSLVPTKDLVGIISIPLKMPVVNKDG TVTEPDMNASFCPELKAPMVLFLDRVYGIDDQSFLMHLLEVGFLPDLRASASLDSEVLRS TETALAMNRYIGSAVLPLLTRCAHLFAHTEHYAMLVDSTLHTIYRLSKGRSLTKAQRDAI DECLLAICKHLRPSMLQQLLRRLVFDVPQLTEYCKMPINLLTNHYEQNWKYYCLPTGLGS YGMASEEELHLTKKLFWGLFDALSQKKYDAELFKMAMPCLSAIAGAIPPDYVDSSPGSTL VKQASVDAQGNFDPQPINTANISLPEKLDYIASKFAEHSHEKWSSEKIALGWTAGDKVDD KAKTHPLLKPYKALSEKERETYRYPVKETLKSMLAMGWNIERTKEGEAMFQQRETEKQRK ISESSQGEFIPAPQDLENVILSRELQAMVETVAENYHNIWANKKKKELGSKGGGSHPLLV PYDTLTAKEKYRDREKAQELFKFLQVNGYAISRGLKDMEQDSSSMEKRIAYKFLKRLLNY VDSAQEFIAHLEAMASSGKTEKSPHDQEIKFFAKVLLPLLDQYFKNHCLYFLSSPNISLS SSGYASNKEKEMITSLFYKLAALVRHRISLFGSDSTTMVSCLHILSRSLDFRTVMKSGSE LVKAGVRTFFENAAEDLEKTLENLKLGKLGQSRTQMKGVTHIISYTSVALLPILTVLFQH ITQHQFGAELLLDDIQQSCYRILTSLYSLGTGKNIYVEKQLPVLGECLSTLVGAMPVAFL EPHLNMHNSQSVFNTKTPRERAILSMPDTVDEMCPEMPHLDGLMKDIGDISESGARYTEM PQVIEVILPMLCNYLSYWWAKGPESSPANTNCSTTVTSEHLSLILGNILKILNNNLGIDN ALWMKRLAVYTQPIISKASPDLLRTHFLPTLEKLKKKTMKIVAEEELLRSESRADTQEAE LQILDEFAVLCRDLYAFYPMLIRYVDNNRSKWLKQPDSDSTELFKMVSEIFILWCKSHNF KREEQNFVVQNEINNLAFLTGDSKTKMSKSGGQDQDRRGKRRKGELYSIQTSLIVAAHKK ISKWLKQPDSDSTELFKMVSEIFILWCKSHNFKREEQNFVVQNEINNLAFLTGDSKTKMS KSGGQDQERRGKRRRGELYSIQTSLIIAAHKKMLPIGLNMCTPGDQELISLAKIRYSLKD TDDEVKDYLRKNLHLQEKSADPAVQWQLNLYKDVVVKNEGPPDPEQNVERVQAISAAVYH LDQVEQPLRNKKMVFQKLLSKQRKRAVVACFRMAPLYNLPRHRSVNLFLSGYQRLWIETE EYSFEEKLVQDLAKTPMTVVEEEEEEEAEVQPDPLHQLILHFSHNALTERSFLEEDPLYI AYADMMAKSCAENEEEEEEEEGKEKTFEEKEMEKQKILYQQARLHARGAAEMVLQMISAS KGRLGPMVTGTLKLGISILNGGNVLVQQKMLDYLKEKRDAGFFKSLSGLMMSCSVLDLNA FERQNKAESLGMVTEEGSTNMRERGSKVLQNDDFTKDLFRFLQLLCEGHNNDFQNFLRTQ TGNTTTVNIIISTVDYLLRLQESISDFYWYYSGKDVIDEAGQLNFSKALAVAKQIFNSLT EYIQGPCIGNQQSLAHSRLWDAVVGFLHVFANMQMKLSQDSSQIELLKELMDLQKDMVVM MLSLLEGNVVNGTIGKQMVDTLVESSSNVEMILKFFDMFLKLKDLTTSDNFKEYDPDCKG VISKKEFHKSMDSQKQYTQSEIGFLLSCVEADENDMFNYKEFVERFHEPAKDIGFNVAVL LTNLSEHMPHDSRLSTFLDLAESVLSYFEPYLGRIEIMGGAKRIERVYFEISESSRTQWE KPQVKESKRQFIFDVVNEGGESEKMELFVNFCEDTIFEMQLASQISEPDAAERPEEEDEE ELHSLLEGLSEEEDASLESASAFIAACASVKKSMSDFRKMLTFKSMRKQFKKFRKLTIRE MITGFFSFFWMLFTGFFKGIFSIIFGFFHIIWSSMFGGGLVEGAKNMKVTDILGNMPDPT QFGIHGDVLEAEKTESSELVVSADMVQMTGAAAEKLETDTIMDLLNPAVKKEGKHGAEPG LGDVCEVLTESSAPVEKKKSQNVAAEKPESEPEKADTENQEKEDKAKEETPEKPAAAKPA PRAKRGSPKEDSPAFMASFFAGLKVYKTKMLNYLTRNFYNLRFLALFVAFAINFILLFYK VTGEFDDEEEEEGSWGGEEEEGDEDDEGMEYFILQESTGYMAPTLTFLAVLHTIISLLCV VGYYCLKVPLVVFKREKEIARKLEFDGLYITEQPSDDDIKGQWDRLVIATPSFPNNYWDK FVKRKVINKYGDLYGAERIAELLGLDKSALDFDPTEEAVVKEASLVSWLSSIDTKYHIWK MGVVLTDNSYLYLIWYTTMSILGHYNNFFFAAHLLDIAMGFKTLRTILSSVTHNGKQLVL TVGLLAVVVYLYTVVAFNFFRKFYNKSEDEDAPDMKCDDMMTCYLFHMYVGVRAGGGIGD EIVDPAGDPYELYRILFDITFFFFVIVILLAIIQGLIIDAFGELRDQQEQVKEDMETKCF ICGIGNDYFDRTPHGFETHTLQEHNLANYLFFLMYLINKDETEYTGQESYVWKMYQERCW DFFPAGDCFRKQYEDQLG NT seq 14817 nt NT seq  +upstreamnt  +downstreamnt atggccgaaggtggtgaaggggaagatgaggttcagttcttacgaactgatgatgaggtg gtactgcagtgtgtcgccgccattcagaaggagaatcgcaaattctgcctatcagcagag ggactcggcaaccgcctgtgttatctagagcccacatcagaggcgaagtattttcctcct gacctatgcatctgtaactttgtgctggagcagtcactctcagtgcgggctctacaggag atgctcgccgggcagaacggtgaaggagcagcacagggaggtggtcatcggacactgctc tacggtcacgccatcctccttaggcattccttcagtggaatgtatctgacatgtctgaag acttccaggtctctgacagacaaactgtcttttgatgttggccttcaagaggattcaact ggggaagcttgttggtggacaattcacccggcatccaagcagaggtcagagggtgagaag gtgcgcattggagatgacctcatcttggtcagcgtgtcctctgagaggtacctgcacctc tccatctccaatggaagcattcaagtggatgcctcattcatgcaaacactgtggaacgtt cagcctacctgctccagaagcaacttggaagtggggtttcttttgggtgggcatgtgata cgcttgttccgtgggcacgacgagagtctcaccattccagaatccgagcaaagccaagac caacagagatgcatactcacaggggagtcttttttcctgaattgcagctggagcgggagt cacatcagatggggtcagcccttccgcctccgccatctctccaccggttactacctgggc cagacagaggaccatggcctgatactgctggacaaagagaagtctgacaccactgcaaca gccttctgtttccggccaagcaaggaaaagattgactccggcccaaagcgtgatattgat ggtatgggggtcgcagagatcaaatacggcgattcggtctgcttcatcatgcatgtgtcc acggggctgtggttgtcctacctggcacctgacgccaaatcttctcgcctgggaccacca aagagaagggctgtcctgtctcctgaaggccatatggatgacgggctgactctgcagctt tgccagcacgaggagtcccgggcggctcgcatcattcgtaataccacccacctcttcact cagttcatcaggggtctggatggtttgaatggggagaagacaacagaggtgacactgcct gtgtgtgaagtgctgcagacactcgatgacctcattgtgtacttccagcagcctgactct gagctcgaacatgaggagaaacagaggcagctccgatctctcatcaagcgccaagatctc ttcaaagaagagggaatgctaaccctggtctcacactgcatcgatcgcctaaacgtgtac aacagtgccgctgagtttgaggaattagcaggcgaagaagctggagaggcgtggaaggac attctcaacctcctctatgagcttctggccactctgattcgaggcaacaggaccaactgc acacagttctctcgcaagctggattggctagtcagcaagctagagcggctggagtcctca tcaggcattttagaggtgcttcattgtatcctaatcgagagtccagaatctctgaacatc atccagaaggcccacatcaaatccattatttctctgctgtacaagcatggacgcaaccac aagattctagatgttctctgttccctgtgtgtctgcaatggtgtggctgtgagagccaat cagaatttcatctgtgaccacctgcttcccaggagagacctactgctccagacacgactg gtcaatgatgtccaaagtatgagacccaacatcttcctgggcatgagtgagggctcggca cagtataagaaatggtactttgagctgatcatcgatcaagtagaccactatgtgaccaat gagcccacccaccttcgtgttggctgggccaccaccaaaggctacgccccctatcctggg ggtggagagggctggggaggaaatggtgtgggtgacgatctttactcctatggttttgat gggcttcatctgtggtcagggcgaatcccacgggccgtggcctctattaaccagcacttg ctgaattcagatgatgttgtgagctgttgtcttgatctcggagcccctagcatgtctttc cgaattaacggtcagcctgttcaaggcatgtttgaagacttcaacatagatggcttcttc tttcccgtcatcagtttctctgcaggggtcaaggtccgtttcttgttgggtggtcgccat ggagactttaagttcctgcctccagcaggctatgcaccatgttatgaagccctgcttccc aaagaaaagatgcgtgtggagcctgtgaaggagtataaaagagacctggagggagtgaga gatctgctgggcaccacagagttcctgtcccaggcttccttcattcctgttcctgttgac accagccagattgtcctgcctccgcatcttgaacatgtgcgggacaagttagctgagaac atccatgagctctggggcatgaacaaaatagagcttggctggatgtatggcaaggtccga gatgacaacaagagacagcacccttgtcttgttgacttctctaaactgccagaaacagaa aagaattataacctgcaaatgtcaactgaaactttgaagaccctacttgctttgggatgc catgtcgcacaagtcaatatgaatgctgaagacgacctgaaaaaaatgaaactccccaag aactacatgatggcaaatggttataaacctacaccactggacctctctgatgtaaaactg acacctggtcaagaggttctagttgataaactggctgaaaatgctcataatgtttgggcc aaagatcgcataaaacaaggatggacctatggtattcagcaggatttgaaaaaccgtcgg aatccacgtctggtgccatatgctttattagatgaacgcactaagaaatcaaatagagac agtcttcgagaggccattcgtactctggttggatatggatatttcatagacccacctgat caagagactgctcacacagtagagaaggaaggtatcgaatccatccgtctcttccgtgtg gagaagatctacgctgtgaagacagggaagtggtattttgagtttgaggcgctcactgga ggtgacatgcgggtgggctgggcacggcccggatgcagacctgataaagaactgggacta gatgaccagtccttcgtctttgatggctacaggggccgccgggttcatatgggcagtcat ttctttgggaggacgtggaataaaggagatgtggtgggctgcatgatcaacatggaggac aaatccatgatattcaccttgaatggagagatcttaatcaccaacaagggctctgagctc tgctttgccgactttgaaactgaagatggattcatcccagtgtgcagcctgggtctttcc caaattggccgcatgaatttaggaaaagccgctagtagttttaagtactacactatgtgt ggccttcaggagggctttgaaccctttgctgtcaacatgaatcgagaggtcaccatgtgg ttcagcaaacgcctgcctacgtttgttaatgtaccagaggaccatccccatattgaggtc actagaatagatgagactgtggacacacctccatgtctaaaggtaacacacaagacatat gggacccagaccagcaatgatgacatggtctgttgtcgtctaagcatgcctgttgagttc cactctggccctcggaagacaactgatatcaatgaggtgatcgctgaggaccaaagagcc aagaaggatgatggaggcaagactgattatggcagcattacaaagcacttctactctgtg agagtgtttgctggacaagatccatcgtccgtttgggtgggctgggtgacaccagactac cactactacagcaaatacttcagcctcagcacagttcgcactgtcactgtaacgctggga gatgagcggggacgtgttcacgagagtgtgaggaggagtaattgttacatggtctgtgct ggtgatgttgtcagcggctccacaggccgtagtaacactgatctggagattggctgctcc atagacctggcctcaggcctggtttcattcactgccaatggcagagatctgcctactgca taccaggttgagcctaacacgaagctcttccctgctgtgtttgttcaacctacgagtccc aacctcttccagtttgagtttccaaaaatcccagatgcaatgcccctgtcttcagccatc tttaagagtttacaaagaaacccagagccccagtgtcctcctcggctggatgtgcagaca cttgtgtctgtgctgtggagcagaatgcccaacaccttcctgtctgtggagacggcccgc gtgagtgagaggcatggctgggtggtgcagtgtctagagcccttgcagatgatggctgtt catatcccagaggagaacaggtgtatcgacatcatggaactatcagaaaatgaagatcta cggcagttccactatcacactttaaaactcttctgtgccctatgtgccctgggcaacacc cgcattgcacacgtcctctgtagtcattttgaccaatcgcagctcttatacaccattgat aaccagtacctgtctggtcaactgcgtgaaggcttttatgatgtcctcatcagcattcac ctggagacggccaaagaggcccatctcatgatgaacaatgagtttataatcccagtaacg gacgagacgaggagcatccgcctcttccctgatgactctaagcgccactctcttcctggc gtaggcttaagcacttcacttgcccctcgtttcaacttcacccctccgtgtttcattacc cccaagcgcgatcagcctctcttcagcccacagatccccctgggtatcctgaaggagaaa gccatcagcatgcttacggaagccgttcagggcggaggtgcccacattcgagatcctgtg ggtggaagcgttgagtatcagtttgtgccgattctcaagctgattggcaccctgctgata atgggggcgctgaccagtgaggaggtgaggaccatcctgcttctcattgaccccagtgtg tttgaggacagtaaggaggaggaggaacagacagcagtggcagaacagggagccgagaaa gaggaggccaccagtaatgaagagaaggctgtggaggctggagaggaagagagtaaagag gccaagcagcctcccaaaggtctactggagaaaagtttgcctgaatcggtcaaacggcag atgtgtgaactgctacactatttctgtgactgtgagctgaagcagcgcattgaagctata gtggccttctcagatgatttcgtgtccaagctgcaatacaatcagaagttccgctacaac gagttgatgcaagccctcaacatgtcagctgctgtcactgccaagaagacaagagagttc cgctcacctccccaagagcagataaatatgttgttgaacttcagtgctggtgatgattgc acctgccctgaggagctgcaagaggagcttcaaggcttccatgatgacctgcgactgcat tgtggcatccctatggaggaggaagaggaggagcaggacacatctcttaaaggccgccta atgtccctggtatacaagattaaaggtcgtccccaaaaaactgaggaaaaaccaacagag caagaacaggctgctcctaccaacctgaaggagctgatatctcagactatggtcacatgg gctcaggagtgcaagatccaagacccggcactggtccgcagcatgttcagccttttgaga aggcagtatgatggcatcggtgagctgctcagggccttgaggaagagctacaccgtcagt gccaagtctgtaggggacgcgacaaacctgttggcctcactgggccagatccgttcacta ctcagcgtccgcatgggggaagaggagggccagctcatgatcgatggcctgggggacatc atgaacaacaaagtgttttaccagcatccaaatctgatgcgtgttcttggcatgcatgag acagtaatggaggtcatggtcaatgtgctgggaggagacaagaataaggagattgccttc cccaagatggtggccagctgttgtcgcttcctatgctacttctgtcgcatcagccgtcag aaccagaaggctatgtttgaccacctgagctacctcctggagaacagcagtgtggggctg gcatgcccagccatgagaggatccacacctttagatgtggctgcctcctctgtaatggac aacaacagtttagctctggcacttgaagaacctgatcttgagaaggtggtgacatatctg gcaggctgtggtttacagaactgcccaatgctcattgccaggggatacccagatatcggc tggaacccaatagaaggagaacgctatttgtccttcctacggtttgctgtctttgtcaat ggtgaaagtgttgaagagaacgctaatgtagtggtgaagcttttgatcaggcgtccggag tgctttggacctgctctcagaggagagggagggcaaggtttactcgctgccatgaaggaa gccatcaagatctcagaagatcctgctttagatctgcctaatttacccgaggggtctgca cccaccgtcggagaggatgaagaggaggaggaggtcgcccacatgggcaactctattatg tccttctactcagcccttattgatcttctgggtcgctgtgcacctgagatgcatcttata aacaaaggcaaaggtgaagcactgcgtatccgtgccatcctccgttccttagttcccact aaggatttggttggaattatcagtattccactcaaaatgccagtcgtcaataaagatggc actgtgacagagccagatatgaatgccagcttctgtccagagctcaaggcacccatggtg cttttcctggaccgtgtctatggcattgacgaccaaagcttcttgatgcacctgctggag gtgggcttcctgccagacctgcgagcatcagcctccctggactcggaggtgctcaggtcc acagagacagccctggccatgaaccgctacattggatccgcagtgcttcctctgttgacc cgctgcgctcatctgttcgctcacactgagcactatgcaatgctcgttgactccacgctg cacactatctatcgcctctcaaagggccgatcactcaccaaggcccagagagatgctatt gatgaatgtctactggccatctgcaagcacctgcggccatcaatgctacagcagcttttg cgtcgtcttgtatttgatgttccacagcttacagagtactgcaagatgcccattaatctt ttgaccaatcactatgagcagaactggaagtactactgtctgccaacaggcctgggcagc tatggaatggcatcagaggaggaactccacctcaccaagaaactcttctggggacttttt gatgctctttctcaaaagaaatatgacgcagagcttttcaaaatggccatgccgtgtctg agtgccatagctggtgccataccacctgactacgtcgactccagtccaggttccacatta gttaagcaggcctctgtggatgcgcaaggcaactttgaccctcagcctattaacactgct aacatctcgctgcctgaaaagctagattacattgcaagcaagtttgctgagcattcccat gagaaatggtcctctgagaagatcgctcttggctggactgcgggagataaagtagatgac aaagctaaaactcatccactgctgaaaccgtacaaagcactgagtgaaaaggaaagggag acttaccgctatcctgtgaaagagactctaaagagcatgttggcaatgggatggaacatt gagaggaccaaagaaggagaggccatgttccagcaaagggaaaccgaaaaacagcgcaag atatcagagtcctcacagggtgagtttattccagccccacaagatttggaaaatgttatt ctatcaagagaactacaggcgatggttgaaacagttgcagaaaattaccacaacatttgg gcaaacaagaagaaaaaggaacttggcagtaaaggaggaggaagtcatccattgttggta ccgtacgacacgctgacggcaaaggagaagtacagagatcgagaaaaggcccaggaactc tttaaattcctgcaggtcaatggatacgccatcagcagaggtctgaaggacatggagcag gattcctcttctatggaaaagaggattgcctataagttcctcaagaggctcttgaattat gtagattctgcacaggagtttatcgctcatcttgaggctatggcttccagtgggaagaca gaaaaatctccccatgatcaagagatcaagttttttgctaaggttctgctgcccctccta gaccagtacttcaaaaaccactgcttgtactttctgtcatcccccaacatcagcctgagc agcagtggctatgcatccaacaaagagaaggagatgatcaccagtctattctataagctg gcagcccttgtcagacatagaatatcactctttggaagtgactccaccaccatggtgagc tgcttgcacatcctgtcacgctcactggacttcaggactgtgatgaagtctggctcagag ctggtgaaggctggtgtcaggacattcttcgagaatgcagcagaagacctggagaagact ctggagaacttaaagctggggaagttgggtcagtcacgcacccagatgaagggcgttacg cacatcatcagctacacctcagtggccctgctgcccatcctgacggtgctttttcagcat atcacccaacaccagtttggagcagagctgcttttggatgacattcagcagtcctgctac cgcatcctgaccagcctctactctttgggcactggcaagaacatctatgtggaaaaacag cttccagtgctgggtgaatgtttatctactctggttggagccatgcctgttgcattcctg gaaccccacctaaatatgcacaattcccaatctgtcttcaacaccaagacaccaagggaa cgagctattttgagcatgccagacactgtggatgagatgtgtcctgagatgccccatctg gacggcctgatgaaggacattggtgacatttctgaatccggagcacgctacacagagatg ccacaggtcattgaggtcatcctgcccatgttgtgtaactacctgtcttactggtgggca aaaggcccagaaagctccccagctaataccaattgcagcacaactgtcacatctgagcat ctcagtctaattctgggcaatatccttaagattctcaataacaaccttggcattgacaac gccctgtggatgaaaagacttgcagtatacacccagcctatcattagcaaggctagccca gatcttcttagaacgcacttcctgccgacgctggagaaactgaagaagaagacaatgaag atagtggctgaggaggagctgctgaggtctgaaagcagggcagacactcaggaagctgaa ctgcagattctggatgagtttgctgttctctgcagggatctgtatgccttctatccaatg ctcattcgttatgtggacaacaacagatccaaatggctgaagcaaccagattcagattca actgaacttttcaaaatggtgtcagagattttcatcctttggtgtaaatctcataacttt aaaagggaagagcaaaattttgtggtgcaaaatgaaattaacaacctggcgttcctcact ggagacagcaagacgaagatgtcaaaatctggaggtcaggaccaagacagaagaggaaaa aggagaaaaggagagttgtactccattcagacttcccttatcgtagcagctcacaagaag atatccaaatggctgaagcaaccagattcagattcaactgaacttttcaaaatggtgtca gagattttcatcctttggtgtaaatctcataactttaaaagggaagagcaaaattttgtg gtgcaaaatgaaattaacaacctggcgttcctcactggagacagcaagacgaagatgtca aaatctggaggtcaggaccaagagagaagaggaaaaaggagaagaggagagttgtactcc atccagacttcccttatcatagcagctcacaagaagatgttacccattggtctgaacatg tgcactcctggagaccaggagctcatttcccttgccaagatccgttacagtctgaaagac acagatgatgaggttaaggattacctgaggaagaacctccatcttcaggagaagtcagca gatccagcagtgcagtggcagttgaacctctacaaagatgttgtggtgaagaatgaggga cctccagacccagagcaaaatgtggagagagttcaggccatctccgctgctgtctaccac cttgatcaggttgaacagccgctgaggaacaagaagatggtgtttcaaaagctgctgtca aagcaaagaaagcgtgccgtggtggcttgtttccgcatggcaccactctacaacttacca aggcatcgctcagttaacctcttcctcagtggctatcagagactttggatagagacagag gagtactcctttgaggagaagctagtgcaggacctggcaaaaactcccatgactgtggta gaggaagaagaggaagaagaagctgaagttcagccagaccctcttcatcagctcatcctt cacttcagtcacaatgctctgacagagagaagtttcctagaagaggatccactctacatt gcttatgctgacatgatggcaaagagctgtgccgagaatgaggaagaggaagaggaagag gagggaaaagaaaaaacttttgaggaaaaagaaatggagaagcagaagattctttaccag caggccagacttcacgcccgaggggctgctgagatggtgctacagatgatcagtgccagt aaaggccgacttggtcccatggtgactggcacccttaaactgggcatttctatcctaaat ggaggcaacgttcttgttcaacagaaaatgctggattatttgaaggaaaaacgagatgcg ggtttctttaaaagtttatctggactaatgatgtcatgcagtgtgctggatttaaatgca tttgaaaggcaaaataaggccgagagtcttggaatggtgactgaagaggggtcaaccaac atgagagagcggggttccaaagtcttacaaaatgatgactttacaaaggatctattcagg tttttgcaacttctgtgcgagggacacaataatgatttccaaaacttcttgcggacacag accggaaacactactacagtcaacatcatcattagcactgtggactacttgttgcgtcta caggaatctataagtgatttttactggtattactctgggaaagatgtcattgacgaggct gggcaacttaacttctccaaagctttggcagtagccaaacaaatctttaactcactcact gagtacattcagggcccttgtattgggaatcagcaaagtttggcacacagcaggttgtgg gacgcagtggtcggattcctgcatgtttttgcaaacatgcaaatgaaactgtcacaggat tctagtcaaatcgagttattgaaagagctgatggatttgcagaaagatatggtggtcatg atgttatctcttctggagggtaatgtggtgaatggaactatcggtaagcagatggttgac acattagtggagtcctccagcaatgtggaaatgatcctcaagttcttcgacatgttcctc aaactgaaggacctcactacatctgataacttcaaggagtacgacccagattgcaaaggc gttatatccaagaaggagttccacaagtctatggatagccaaaagcaatacacacagtct gagatcgggtttcttctctcctgtgtggaggcagatgaaaatgacatgttcaactacaag gagtttgtggaacgcttccatgaaccagccaaggacatcggcttcaacgtggctgtgctt cttactaacctatcagagcacatgcctcacgactcacgcctgtccacctttttagacctg gctgaaagcgttctcagttactttgagccgtacctgggccgcattgaaatcatggggggt gccaagaggattgagagggtttactttgagatcagcgagtctagcagaacccaatgggaa aagcctcaggtcaaagagtccaaacggcaattcatctttgatgtggtcaatgaaggtggt gagagtgagaagatggagttatttgtgaacttctgtgaggacaccatctttgagatgcag ctggcctctcagatctctgagccagatgcagcagaacgacctgaggaggaggatgaagag gagttgcacagtctgcttgaaggcttgtctgaggaggaagatgcatctcttgagtcggcc tcggccttcatagcggcctgcgcctctgtgaagaagagcatgtctgatttccgtaaaatg ctgacgtttaagagtatgaggaaacagtttaagaaattcaggaaactgaccatcagggaa atgatcacagggttcttctcctttttctggatgctcttcaccgggttcttcaaaggcatt ttcagcatcatctttgggttcttccatattatttggtcctccatgtttggagggggtctt gtggagggtgctaaaaacatgaaagtgacagatatcttgggtaacatgcctgatccaaca cagtttgggatccatggtgatgtactggaagcagaaaaaaccgagagcagcgagttggtg gtgtcggcagatatggtgcagatgactggcgctgctgctgagaagctggagacggatacg attatggatctacttaatccagctgtgaagaaggaggggaagcatggggcagaacctggt ctgggtgatgtctgtgaagtcctgacagagtctagcgcccctgttgagaaaaagaagagc cagaatgtagcagcagagaagccagaatccgagccagagaaagctgacactgagaatcag gagaaagaagacaaggctaaagaggaaacacctgagaaaccagcagcggcaaaaccagct ccaagagccaaacgtggctcaccaaaggaagactctccagcattcatggccagcttcttt gcagggcttaaagtctacaaaaccaaaatgctgaactacctgactcgcaatttctacaac cttcgttttctggccctgtttgtggcctttgccatcaacttcatcctgctcttctacaag gtgactggagaattcgatgatgaggaagaggaagagggatcctggggtggtgaagaggag gaaggtgatgaagatgatgaaggaatggaatacttcattcttcaggagagcactggctac atggcacccacattgacgttcttggctgtactgcacacgatcatctccttactctgtgtc gttggatattactgccttaaggttcctttagtcgtgttcaagcgggagaaggagatcgct aggaagcttgagtttgatggtttgtatattactgagcagccgtctgatgatgacatcaaa ggacagtgggatcgtttggtcattgcaactccgtccttccctaacaattactgggacaaa tttgttaagaggaaggtcatcaataaatatggtgacttgtacggggctgaacgcatagct gaactcctgggtctggataagagtgctctggactttgatcccactgaagaagccgtggtg aaggaagcctccctggtgtcctggttgagctcaattgataccaagtaccacatctggaaa atgggggtggtgctgacggacaactcttacctctacctgatctggtacaccaccatgtct attttgggacattacaataacttcttctttgccgctcatttgctggacattgccatgggc ttcaagaccttgaggaccatcctctcttctgtgacccacaatggcaaacagctggtgttg accgtggggctcctggcggtcgtggtctacctgtacaccgtggtggcttttaacttcttc cgcaagttctacaacaagagcgaggatgaggatgcgcctgacatgaagtgtgatgatatg atgacttgctacctgttccacatgtacgtgggtgtgagagctggcggtggcatcggtgat gaaatcgtggacccagccggtgacccatacgagctctaccgcattctgtttgacatcacc ttcttcttctttgtcatcgtcattctgctggccatcattcagggtttgatcattgatgcc ttcggtgagctgagagaccagcaggagcaggtgaaagaggacatggagacaaaatgcttc atctgtggaattggaaatgactacttcgacagaacccctcatggctttgagacccatacc ttacaagagcacaatctggccaactatttattcttcctgatgtatcttatcaacaaagat gagactgaatacactggtcaggagtcgtatgtttggaagatgtatcaggagaggtgctgg gatttcttccctgccggagactgtttccggaagcaatacgaggaccagctgggctag

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