Streptomyces anulatus: KZO11_27410
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Entry
KZO11_27410 CDS
T09280
Symbol
leuC
Name
(GenBank) 3-isopropylmalate dehydratase large subunit
KO
K01703
3-isopropylmalate/(R)-2-methylmalate dehydratase large subunit [EC:
4.2.1.33
4.2.1.35
]
Organism
sanl
Streptomyces anulatus
Pathway
sanl00290
Valine, leucine and isoleucine biosynthesis
sanl00660
C5-Branched dibasic acid metabolism
sanl01100
Metabolic pathways
sanl01110
Biosynthesis of secondary metabolites
sanl01210
2-Oxocarboxylic acid metabolism
sanl01230
Biosynthesis of amino acids
Module
sanl_M00432
Leucine biosynthesis, 2-oxoisovalerate => 2-oxoisocaproate
Brite
KEGG Orthology (KO) [BR:
sanl00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00660 C5-Branched dibasic acid metabolism
KZO11_27410 (leuC)
09105 Amino acid metabolism
00290 Valine, leucine and isoleucine biosynthesis
KZO11_27410 (leuC)
Enzymes [BR:
sanl01000
]
4. Lyases
4.2 Carbon-oxygen lyases
4.2.1 Hydro-lyases
4.2.1.33 3-isopropylmalate dehydratase
KZO11_27410 (leuC)
4.2.1.35 (R)-2-methylmalate dehydratase
KZO11_27410 (leuC)
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GFIT
Motif
Pfam:
Aconitase
Motif
Other DBs
NCBI-ProteinID:
QYA97078
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Position
6210432..6211859
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AA seq
475 aa
AA seq
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MGRTLAEKVWDDHVVRRAEGEPDLLFIDLHLLHEVTSPQAFDGLRQAGRPVRRLDLTIAT
EDHNTPTLDIDKPIADPVSRAQLETLRKNCADFGVRLHPLGDVEQGVVHVVGPQLGLTQP
GTTVVCGDSHTSTHGAFGALAFGIGTSQVEHVLATQTLPLARPRTMAITVEGELPDEVTA
KDLILAIIARIGTGGGQGYILEYRGSAIEKLSMEARMTICNMSIEAGARAGMIAPDATTF
DYLKGRDHAPEGEDWDAAVAYWKTLRSDDDAVFDAEVVIDATELAPFVTWGTNPGQGAPL
SANVPDPASYEDASERFAAEKALEYMGLTAGQPLRDINVDTVFVGSCTNGRIEDLRNAAS
ILDGRKVANGVRMLVVPGSVRVALQAVSEGLDKVFTEAGAEWRHAGCSMCLGMNPDQLAP
GERSASTSNRNFEGRQGKGGRTHLVSPQVAAATAVLGHLASPADLSDARTPAGVR
NT seq
1428 nt
NT seq
+upstream
nt +downstream
nt
atgggtaggacactcgcggagaaggtctgggacgaccatgtcgtccggcgcgcggagggc
gagcccgaccttctcttcatcgatctgcacctgctgcacgaggtgaccagcccgcaggcc
ttcgacgggctgcgccaggccggacgtccggtacgacgcctcgacctcaccatcgccacc
gaggaccacaacaccccgaccctcgacatcgacaagccgatcgccgacccggtatcgcgc
gcccagctggagaccctgcgcaagaactgcgcggacttcggcgtgcggctgcacccgctg
ggcgacgtcgagcagggcgtcgtacacgtggtcggcccgcagctggggctgacccagccc
ggcaccacggtggtctgcggcgactcccacacctccacgcacggcgcgttcggcgcgctg
gcgttcggcatcggcaccagccaggtggagcacgtcctcgccacccagacgctgccgctg
gcccgccccaggaccatggccatcacggtcgagggcgagctgcccgacgaggtcaccgcg
aaggacctgatcctggcgatcatcgcccggatcggcaccggcggcggccagggctacatc
ctcgaataccgcggctccgccatcgagaagctctcgatggaggctcggatgaccatctgc
aacatgtcgatcgaggccggcgcccgtgcgggcatgatcgccccggacgccaccaccttc
gactacctcaagggtcgcgaccacgcccccgagggcgaggactgggacgccgccgtcgcg
tactggaagaccctgcgctccgacgacgacgcggtgttcgacgccgaggtcgtcatcgac
gccaccgaactggccccgttcgtcacctggggcaccaaccccggccagggcgcgcccctg
tcggccaacgtccccgacccggcttcgtacgaggacgcctcggagcgcttcgccgccgaa
aaagccctggaatacatggggttgaccgcagggcagccgctgcgcgacatcaacgtcgac
accgtcttcgtaggttcgtgcaccaacggccgcatcgaggacctgcgcaacgcggcctcg
atcctggacggccgcaaagtcgcgaacggcgtacggatgctggtcgtccccggctcggtc
cgggtcgccctccaggccgtctccgagggcctggacaaggtcttcaccgaggccggagcc
gaatggcggcacgcgggttgctcgatgtgcctcggcatgaaccccgaccagctcgccccc
ggcgagcgctccgcctccacctcgaaccgcaacttcgaggggcggcagggcaagggcgga
cgcacccatctggtctcgccccaggtcgccgccgccaccgcggtgctgggccatctggcc
tcgcccgccgacctgtccgacgcccgtacccccgccggagtccgatag
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