KEGG   Streptomyces antimycoticus: QR300_28675
Entry
QR300_28675       CDS       T09335                                 
Symbol
leuA
Name
(GenBank) 2-isopropylmalate synthase
  KO
K01649  2-isopropylmalate synthase [EC:2.3.3.13]
Organism
sant  Streptomyces antimycoticus
Pathway
sant00290  Valine, leucine and isoleucine biosynthesis
sant00620  Pyruvate metabolism
sant01100  Metabolic pathways
sant01110  Biosynthesis of secondary metabolites
sant01210  2-Oxocarboxylic acid metabolism
sant01230  Biosynthesis of amino acids
Module
sant_M00432  Leucine biosynthesis, 2-oxoisovalerate => 2-oxoisocaproate
Brite
KEGG Orthology (KO) [BR:sant00001]
 09100 Metabolism
  09101 Carbohydrate metabolism
   00620 Pyruvate metabolism
    QR300_28675 (leuA)
  09105 Amino acid metabolism
   00290 Valine, leucine and isoleucine biosynthesis
    QR300_28675 (leuA)
Enzymes [BR:sant01000]
 2. Transferases
  2.3  Acyltransferases
   2.3.3  Acyl groups converted into alkyl groups on transfer
    2.3.3.13  2-isopropylmalate synthase
     QR300_28675 (leuA)
SSDB
Motif
Pfam: HMGL-like IPMS_D2 LeuA_dimer
Other DBs
NCBI-ProteinID: WJD99639
LinkDB
Position
6702321..6704117
AA seq 598 aa
MTTHSDTPGHSATSGSAVGRPTPLTAATVTQRPSGMPIHKYGPYEAVDIPDRTWPDNRIT
VAPRWLSTDLRDGNQALIDPMSPARKREMFDLLVRMGYKEIEVGFPSSGQTDFDFVRSII
EEGAIPEDVTISVLTQAREELIERTVESLRGAHRATVHLYNATAPTFRRVVFRGTREQVK
QIAVDGTRLVVEYADKILGDETVFGYQYSPEIFTDTELDFALEVCEGVMDVWQPEEGREI
ILNLPATVERSTPSTHADRFEWMSRRLSRREYICLSVHPHNDRGTAVAAAELAIMAGADR
IEGCLFGQGERTGNVDLVTLGMNLFSQGVDPQIDFSQIDEVRRTAEYCNQMEIHPRHPYA
GDLVYTSFSGSHQDAIKKGFEALEASAAEQGKTVDEIEWAVPYLPIDPKDVGRSYEAVIR
VNSQSGKGGIAYVLKNDHNLDLPRRMQIEFSKTIQAKTDAEGGEVTPGQIWAAFQDEYLP
TDDNRWGRIALRSAQTSTTSEGTDALTVETVVDGTETVLTGTGNGPLAAFFDALASIDVD
VRLLDYSEHTLSEGAASQAAAYIECAIDGQVLWGVGIDANIVRASLKAVVSAVNRARR
NT seq 1797 nt   +upstreamnt  +downstreamnt
atgacgactcattccgatacgcccggccattccgcgacctccggcagcgccgtcggccgt
cccacgcccctcacggccgcgaccgtcacccagcgcccctccggtatgccgatccacaag
tacggcccgtacgaggccgtcgacatcccggaccgcacctggccggacaaccgcatcacc
gtcgccccgcgctggctgtccaccgatctgcgggacggcaaccaggcgctgatcgacccg
atgtccccggcccgcaagcgcgagatgttcgacctgctggtgcgcatgggctacaaggag
atcgaggtcggcttcccctcctccggccagaccgacttcgacttcgtacggtcgatcatc
gaggagggcgcgatcccggaggacgtgacgatctccgtcctcacccaggcgcgcgaggag
ctgatcgagcgcaccgtggagtcgctgcgcggggcgcaccgggccaccgtgcacctgtac
aacgccaccgcccccaccttccgccgcgtcgtcttccgcggcacccgggagcaggtcaag
cagatcgcggtggacggcacccggctggtggtggagtacgcggacaagatcctcggcgat
gagacggtcttcggctaccagtacagcccggagatcttcaccgacaccgagctggacttc
gcgctggaggtctgcgagggcgtcatggacgtctggcagcccgaggagggccgcgagatc
atcctcaatctgccggccaccgtcgagcgctcgaccccgtccacccacgcggaccgcttc
gagtggatgtcccgccggctgtcccggcgcgagtacatctgcctgtcagtgcatccgcac
aacgaccgcggcaccgccgtcgccgccgccgagctggcgatcatggccggggcggaccgg
atcgagggctgtctgttcgggcagggcgagcgcaccggcaatgtcgacctggtgacgctg
ggcatgaacctgttctcccagggcgtcgacccgcagatcgacttctcgcagatcgacgag
gtccgccgcaccgccgagtactgcaaccagatggagatccacccgcgccacccctacgcg
ggcgatctggtctacacctccttctccggctcccaccaggacgccatcaagaagggattc
gaggcgctggaggcgagcgccgccgagcagggcaagacggtggacgagatcgagtgggcg
gtcccgtacctgcccatcgaccccaaggacgtcggccgctcgtacgaggccgtgatccgg
gtgaattcgcagtccggcaagggcggcatcgcctatgtcctgaagaacgaccacaacctg
gacctgccgcgcaggatgcagatcgagttctccaagacgattcaggccaaaaccgatgcc
gagggcggcgaggtcaccccgggccagatctgggcggccttccaggacgagtacctgccg
accgacgacaaccggtggggccggatcgcgctgcgcagcgcgcagacgtccaccaccagc
gagggcaccgacgcgctcaccgtcgagacggtcgtggacggcaccgagacggtgctgacc
ggcaccggcaacggcccgctggcggccttcttcgacgccctggcctcgatcgatgtggac
gtacgactgctggactactccgagcacaccctgagcgagggcgccgcgtcccaggccgcc
gcgtacatcgaatgcgcgatcgacgggcaggtgctgtggggtgtcgggatcgacgccaac
atcgtgcgggcctcgctcaaggcggtcgtctccgcggtgaaccgggcgcgccggtga

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