Streptomyces angustmyceticus: K7396_26505
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Entry
K7396_26505 CDS
T07927
Name
(GenBank) UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase
KO
K01929
UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase [EC:
6.3.2.10
]
Organism
sanu
Streptomyces angustmyceticus
Pathway
sanu00300
Lysine biosynthesis
sanu00550
Peptidoglycan biosynthesis
sanu01100
Metabolic pathways
sanu01502
Vancomycin resistance
Brite
KEGG Orthology (KO) [BR:
sanu00001
]
09100 Metabolism
09105 Amino acid metabolism
00300 Lysine biosynthesis
K7396_26505
09107 Glycan biosynthesis and metabolism
00550 Peptidoglycan biosynthesis
K7396_26505
09160 Human Diseases
09175 Drug resistance: antimicrobial
01502 Vancomycin resistance
K7396_26505
Enzymes [BR:
sanu01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.2 Acid-D-amino-acid ligases (peptide synthases)
6.3.2.10 UDP-N-acetylmuramoyl-tripeptide---D-alanyl-D-alanine ligase
K7396_26505
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Gene cluster
GFIT
Motif
Pfam:
Mur_ligase_M
Mur_ligase_C
Mur_ligase
PhageMin_Tail
Motif
Other DBs
NCBI-ProteinID:
UAL69656
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Position
5991326..5992777
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AA seq
483 aa
AA seq
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MISLSLAEIASIVGGRQYDIPDDGLRVTGPVVADSRAVCPGALFVAFAGERADGHDFAPG
AVEAGAVAVLAARPVGVPAIVVDDVVAALGALARAVVERLGTTVVGLTGSAGKTSTKDLI
AQLLQRTGPTVWPEGNLNNEIGLPLTALRADETTRHLVLEMGARGVGHIRYLAGLTPPRI
GVVLNVGSAHIGEFGGREQIALAKGELVEGLPAAEDGGVAVLNADDPYVRAMVPRTRART
ILFGEAEDAAVRAENVRITEAGQPAFTLHTPSGCSDVTMRLYGEHHVSNALAAAAVAHEL
GMPADEIATALSEAGTLSRWRMEVTERADGVTVVNDAYNANPESMRAALRALVAMGSAAK
AKGGRTWAVLGEMAELGEDALAEHDAVGRLVVRLNVSKLVAVGGREAAWLDMGAKNEGSW
GEESVHVSDARAAVDLLRSELRPGDVVLVKASRSVGLERVAAALLDDGSTLGAAGAEGGV
ASR
NT seq
1452 nt
NT seq
+upstream
nt +downstream
nt
gtgatctccctgtcgctcgccgagatcgcgagcatcgtcggcggccggcagtacgacata
ccggacgacggcctccgggtgaccggcccggtcgtggcggactcccgcgcggtgtgtccc
ggcgccctgttcgtggcgttcgccggtgaacgcgccgacggccacgacttcgcgccgggc
gccgtcgaagcgggcgcggtggccgtgctggccgcccgccccgtcggcgtccccgcgatc
gtcgtcgacgacgtggtcgcggccctcggggcgctcgcccgcgccgtggtcgagcggctg
ggcaccaccgtcgtcgggctgaccggctcggccggcaagaccagcaccaaggacctgatc
gcccagctgctgcagcgcaccggcccgacggtctggccggagggcaacctcaacaacgag
atcgggctgccgctgaccgcgctgcgcgccgatgagacgacccgtcacctcgtcctggag
atgggcgcccgcggcgtcggccacatccgctacctcgccgggctgaccccgccgaggatc
ggtgtggtgctgaacgtcggcagcgcgcacatcggcgagttcggcggccgtgagcagatc
gccctggccaagggcgaactcgtcgaggggctgccggcggccgaggacggcggggtcgcg
gtgctcaacgccgacgatccgtacgtgcgtgccatggtcccccgcacccgtgcccggacg
atcctgttcggcgaggccgaggacgccgcggtacgtgccgagaatgtccggatcacggag
gccggacagcccgccttcacgcttcacacaccctccgggtgcagcgatgtgaccatgcgg
ctgtacggtgagcaccacgtgtcgaacgcgctcgccgcggccgccgtcgcccatgagttg
ggcatgcccgcagacgagatcgccaccgcgctctccgaagccggcacgctctcccgctgg
cggatggaggtcaccgagcgcgcggacggcgtgacggtcgtcaacgacgcctacaacgcg
aatcccgagtccatgcgagcggcgctgcgtgcgctggtcgccatgggctccgccgccaag
gcgaagggcggtcgtacgtgggcggtgctcggtgagatggccgagctcggcgaggacgcg
ctcgccgaacacgacgcggtcgggcgcctggtcgtccggctcaacgtcagcaagctcgtg
gcagtcggcggcagggaagcggcctggctcgacatgggcgccaagaacgagggttcgtgg
ggtgaggagtcggtgcacgtgtccgacgcgcgggcggcggtcgacctgttgcgcagcgag
ctgcgaccgggagacgtcgtgctggtgaaggcgtccaggtcggtggggctggagcgggtc
gccgcagcattgctggacgacggaagcacgctgggcgccgcgggcgccgagggcggagtc
gcgtcccgatga
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