Scedosporium apiospermum: SAPIO_CDS4826 Help Entry SAPIO_CDS4826     CDS       T06367                                  Name (RefSeq) putative Hybrid NRPS/PKS enzyme   KO K15394   hybrid polyketide synthase / nonribosomal peptide synthetase ACE1 Organism sapo  Scedosporium apiospermum Brite KEGG Orthology (KO) [BR:sapo00001]  09180 Brite Hierarchies   09181 Protein families: metabolism    01008 Polyketide biosynthesis proteins [BR:sapo01008]     SAPIO_CDS4826 Polyketide biosynthesis proteins [BR:sapo01008]  Polyketide synthase (PKS)   PKS-NRPS hybrid    Fungal type (iterative)     SAPIO_CDS4826 BRITE hierarchy SSDB OrthologParalogGFIT Motif Pfam:  ketoacyl-synt Condensation AMP-binding KR Acyl_transf_1 NAD_binding_4 Ketoacyl-synt_C PS-DH Methyltransf_12 PKS_DH_N Methyltransf_31 PP-binding Epimerase KAsynt_C_assoc Methyltransf_11 Methyltransf_25 Methyltransf_23 CurL-like_PKS_C adh_short DUF7080 RhiE-like_linker Ubie_methyltran Methyltransf_16 Thiolase_N 3Beta_HSD Anamorsin_N mRNA_G-N7_MeTrfase Toprim AMP-binding_C ACP_syn_III Motif Other DBs NCBI-GeneID:  27723898 NCBI-ProteinID:  XP_016643165 UniProt:  A0A084G7Q4 LinkDB All DBs Position Unknown AA seq 4052 aa AA seqDB search MAAKSVHDYPNEPIAIVGSACRFPGDSSSPSQLWDLLREPRDVLQEIPDSRFNPDGFYHE DPLHHGTSNVRHAYLLNEDVGLFDAQFFGIKPVEANSVDPQQRILLEVVYEGLERAGLKL ESLQGSKTGVFVGVMSADYMELLARDIDAFPTYFASGTARSILSNRISYFFDWHGPSMTI DTACSSSLFALHLAVQSLRAGESPAAVVAGANLALSPEQFVAESKLKMLSPDGRSRMWDK DANGYARGDGVAALVLKTLSAALADGDAIQCIIRETGINQDGRTKGITMPSPTAQADLIW STYKKAGLDLSRPADRPQYFEAHGTGTPAGDPVEAEAIRTAFFGPSVGFKRSASEPPLYV GSIKTVIGHTEGTAGVAGIIKGALALQNGIVPPNLLLNELNPNVAPFYKDLEIPKRATEW PTLLPDVVRRVSINSFGFGGANAHAILEEYKPESIPHPVVPPQDTHLSPFNFSASSEKAL TGILSAYSSYLRANPLTNLRDLAWTLNCRRSVLPLRLTVAASNVDTLSTKLGSLAESLSG VVAASNRAPLSSTNPKLLGIFTGQGAQWASMGAKLLATSKLASDRISQLQQSLDSLPREH VPSWRLLEELSKDKANSRISEATFSQPLCTAVQIIIVDHLKAAGVHLAAVVGHSSGEIAA AYAAGYISAQDAIRIAYYRGYFLHLSEGPEGSGGGAMMAVGMTYQDAQELCELEELEGRI CIAASNSPESLTLSGDAHAIDLARQILEDEKKFARLLKVDKAYHSHHMLPCARPYIEALI DAGVKVQPRELNGEYPSWISSVYGEDIESVGLDTLSAEYWSRNMVNQVLFSQALEHAISA KGPFSLAIEVGPHPALKSPALQTFVAVAGGEVPYVGTLRRGAHDGEALAEGLGSIWQYLG AEAINFSAFDRQLHGGGSPEHRPKLLLDLPSYVWEHDRVYWHESRYSRSFRTNAQRPHQL LGTRLPDGTENEIRWKNYLHPRELPWLVHHQVDRQIVFPAAGYLSAVVEAVVQIYGLGSI QVIDLYKVVIGQALVLEENSSVETLFSFRVIEASDIHVEAVFSFFSASTKDSISMSKNAS GNLRITLGAPSPDALPSPYKSEREFLEVDPQRFYNTVRDVGLGYTGPFQKIIEAQRRSGE SSGIIQTPDAEDEGSAAALIIHPGTLDCAIQSIILAYSFPGDGRMRSIYLPTSIDRLRID PAGIVHHKGSSASSHLGFFASITSNRPTDLSGDVEIHSQDGSTTLVQLQGLRTTPLTPAV PSNDLQLFFKTSWQVDAPTGNPGLWEGGENSYDYDLAFAQERVAYYYIRLLNEAIPPSKR SDLEWYHKVFYEYIDHTLAWVNKGTHPFAKPEWSKDTQYDLLKIFERFPDSIDLRIMRAV GTNLVSAMQKEMNILEAMMKDNMLNDFYATSLGMREYLQDLARMVGQLSHRYPHMNVLEI GAGTGGATDMIFQQLQGSFASYTYTDISSGFFENAQVKFDRHRGKMSFKVLDIEKDIMEQ GYAPHSFDLIIASLVLHATRDLDETMHNVRKLLKPGGRLIMLEITDNDPIRFGFIFGGLP GWWLGYDQGRKLSPCVGIEEWEALMLKTGFSTIEAITSHNKTFPLPLSVIATKAIDDRVA FLQNPLVSGAEVNLGLDSLVILGGSTSKTAEVASAIESAVIRQYKSKPKRVLYLEDISQQ DLPFLGSLVSLLDLEEESTFEQMTPGKLSALQEIFKQNRTVLWVTRGALGGSPYRNMYRG LQRTMEKELKHLRVQMLDFASDADVDGETIASKLLQLEAVNAWEQSDDTANLLWYPENEV LVQNAQTLVPRIRLDLERNRRYNSGRRLITQEVRLGQTVVTVRHSGSNFVIEQRSDTQTT AARPGYVDVCPEYSLLKTVKLPSGGFLYLSTGHDVMTEEQVIALSVALESRIRTPESWVL RLNSESEEESKRVLLGLYLQLLTENILWGVKPGESVAILNPCHSLGNVLTQNSAERGVNL ILLTDAAAGREITARPWTSIHPRATKHALGRVIPRNLRRFIHTNDNSELISAIIHALPPK CEIVNQQGFTSLEASVGLTYSAVSAVSGHLKVAWTRSVLEVTVPESHPLVGISQLAQLHV PSSATKQTFLSWSSLPSAPVQLRPATDVVHFAKDKTYWMVGLTGSLGLSLCEWMAQRGAK YIALSSRNPRVDDGWKQAMADLGCTVRVFANDVTNRDEVFALHKRISETLPPIAGVAQGA MVLDDALFPDVDIERFHKITKPKVNGSIYLDELFSSDQLEFFVFFSSVAYVTGNAGQSIY GAASAFMASLATQRRRRGLAASVINIGAILGTGYVSRELSLQQQEYLRKVGLVWMSEQDA HEIFAEGILASRVDSPDSHEFETGLRTDEGRSRDIVSEPPMLQHLGIKGNAASSGGGIQT KQNVQTRARLLEATSREQVFEILKEGFLLKLQAALQADPNKPMLDLSLDEIGADSLVAVD IRSWFLKESGVDVPVLKILNSSSVRELLLFAHDSVPKDVTPNVLGDSDNSLKPAVVSAGV AEAEDFLQPNHKSTSDSDGAPQSSSQSDTRDSEEGEITPRSSEVPSEADRDDFPKPTNPQ ELTIPGFIGNEKVTPERIVPMSFGQSRFWFLKHYVQDQTAFNITTVIKLQGRLRVDALEG ALRAVGQRHEALRTLFFVDQKTKEPKQAILPTSLLRLEKVAISDEGELAKAVLEAKQHIF DIERGEALRIQLLSLSPTAHWIVLGYHHIYMDGIGYVVFISDWERAYNGVLNTQPSDILQ YPDFSLRQIREYQTGTWSDELSFWRSQFPDLPNALPLLPVSRLSTRPISSGFGSYSASFR IDRNLTERISQVCRQFKVTSFHLHLAVFHILLYRYASLIDDMCIGIADGNRKDADVQGSL GIFLDLLPIRLRRSPQDTFANTLKDVRKTTLAAFGNSRVPFDVLLNELNVPRVPSHSPLF QAFVNYRQNHQESRSLFGCDGELDIIATGQTDYDVSVDILDLSAEGGESVVSLGVQKDLY DQHAAEVLAESYHALLRQFTNNPAARVTWVTLYSNESVKDALQLGRGTEAPGKYPTIVHR IDAMVEKYPNQTAVKDAYGKVFTYHELAGRVDSIAQNLLRLGIGNTSNVGVFQTRSAEWI FSLLAILRVGAAYVAMDVNVGPDRLSLIVDNCKPAAILVDSDTESDAFVIATQSQRPSTS PSTSEVRIPIINITDPQPSNEVGTAPNSARPADAAVIIYSSGSTGVPKGVVLSHSNIANY ADVVPPTWGGVREGHEIFLNQASYSFDVSLQQTIVALGIGSTVVVVGNQARGDPAALLKL IIAENITVTGATPTEYLTWARHWDVDLLRKSQWRHAFTWGEPITKQQVRDLQLLGLPNLN VIDAYGPAEATITSAHGRVNLEHIKLESTTRSPNVPLTITPNGSVYIVDESLNPVPPGVL GEIVLGGAAVAKGYLNDESLTSERFIQDKFASPYFKSKGWTTAHRTGDRGFLTADGGLVL QGRIEGSTQVKLAGIRVDVQDVEATIIQAVPDVSQVVVSVRRGAESDSAPFLVAFVILSN NAAGLPADEKTRFLEDLPRNLPLPQYLKPAVVVSVDHLPTNSSHKLDRRLIDGWPLPTEG AQATNPSGDESSTLTEFEQTLRQLWGDALPDGLAQHRSIGGSSDFFHIGGSSLSLINLQG LIKERLNFPISLYKLFQNSTLSSMAASLRNERTVIDELTAVDWELETTLPLDIVRQDSEE TEYTGTVLPVRNVALTGSTGFIGKEILRRLIADDRISKVYCLAVRKKRSDLPPSLFGHEK VVVYSGDLGAPRLGLSETEVAAVFGTQGVAADAVIHAGADVSFLKTYHSLRLVNVASTRE LIRLAAPRRLPLHFISSATVARLALQAGRTSFGRESIANYPPNATRAAVEDGYVAAKWTS EVLVENAAKQLGLPVFIHRPTSVTGEDASDLDLMSNITKYVQKTRTIPDTHEWNGGFDFV SVQTVGQDIVREVLDNDQVGGEVRYVFQAGENVVDSHKMQSILELGTGTSFEVLPFDQWV DGAEQAGLSHLLALYLRRAAKGQLLIPKLLNE NT seq 12159 nt NT seq  +upstreamnt  +downstreamnt atggctgcaaagagtgtccacgactatcctaacgagcccatagctattgtcggtagcgct tgtcgctttccgggcgattcatcatcgccgtctcagctgtgggatctgctccgtgagccg cgagatgttttgcaggagattccagatagccgcttcaatccggatggcttttatcatgag gatcctttgcaccatggcacctcaaatgttcggcatgcatatcttcttaacgaagatgtt gggctattcgatgcacagttctttggcatcaaacccgttgaggccaactcggtagacccg cagcagcgaattctcctggaagtcgtgtacgaaggtttggaaagagctggtctgaagctt gagagtctgcagggctccaagaccggtgtcttcgtcggtgtcatgagtgcagactacatg gaactcctcgcacgcgacattgacgcatttccaacctacttcgcctccggcacggctcga agtatcctgtccaaccgtatttcttactttttcgattggcatgggccgtctatgaccatc gacacggcctgttcgtcgagtctttttgctctacatttagccgtccaaagccttcgtgct ggagaatcccctgctgccgtcgtggccggggctaacttggccttgagccctgaacagttc gttgccgagagtaaactcaagatgctttcgccagacgggagatcgcgcatgtgggataag gatgccaacgggtatgcgcgaggagatggggttgccgccttggtgttgaagaccttgagt gcagccttggcagatggagatgcaattcaatgtattatccgggagacggggattaatcag gatggccgcaccaagggaatcaccatgcctagtcctaccgcccaggccgatctcatctgg tccacgtataagaaggccgggcttgatttatcgagacctgccgacagacctcaatatttc gaagcccatggcactggtacacctgctggtgacccagtggaagcggaagccatccgaact gctttcttcggaccgagcgtgggattcaagcggtctgcttcggagccaccgctatacgtc ggctcgataaagacggttatcggacatacagagggaacggctggcgttgctggtattatc aaaggtgcccttgcacttcaaaatggcatcgttccaccgaacctgcttctgaatgagcta aacccaaacgtcgccccattctataaggatctcgagattcctaagcgggccacagaatgg cctaccctcctcccagacgttgtgcgccgcgtgagcatcaacagcttcggtttcggaggc gcaaacgcccacgctattctggaggagtataagccggaatccattccccaccctgtcgtt cctccccaggatacccatctcagtccgttcaacttctccgcttcttcagagaaggcgctt accgggatcctttcggcatactcgtcctatctccgcgcaaatccattgaccaacttgcgg gatcttgcctggaccctgaattgtcgccgctccgttcttcccctccgactgacagtcgcg gcatcaaatgtcgataccctctctacaaagcttggtagtttagccgagtcactttctggt gtggtcgccgcgagcaacagagctccccttagttcgacaaatccgaaacttcttggtatc ttcacgggacaaggtgcacaatgggcatcgatgggagcgaaactgttggctacatcaaag ctggcatcagatcgcatttcacagttacaacagtcactcgacagtctccctagggaacac gttccatcgtggagacttttggaagagctttctaaggacaaagccaactctcgcatctcg gaagcaactttctcgcaacctctgtgcacggctgtccagatcattatcgttgatcactta aaagctgctggtgttcatcttgcggcggtggtgggccattcgtctggtgaaattgcagcc gcttatgccgccggctacatctctgcacaggacgcaattcggatcgcctactatcgcggg tacttcctccatctgtctgaagggcctgagggctctggaggcggtgcaatgatggccgta ggcatgacttaccaggacgctcaagagctctgcgagctagaagagctcgagggccgaatc tgcattgccgcaagcaattctcccgagagtctgaccctgtccggggacgctcacgccatt gacctcgcgcggcaaattctcgaggacgaaaagaaattcgccaggctcctgaaggtggat aaagcataccactcccatcatatgcttccttgtgctcgcccctacattgaagcgctcatc gatgctggggtcaaggtccagcccagggagcttaacggtgagtacccgtcatggatctct agcgtctacggtgaggatattgagagcgtcggcctcgataccctgtccgcggagtactgg agcagaaatatggtcaaccaagtccttttttcgcaggctcttgagcatgcaatcagcgca aagggacccttctcgctggcaattgaagtgggaccacatccagcgctcaagagccctgcc ttgcagacatttgtagctgtcgccggtggcgaggttccttacgtagggactctccgtcgc ggagcgcacgatggtgaagcccttgccgaggggcttggttccatctggcagtacctaggc gcagaggctattaatttctccgcattcgaccgtcaattgcatggtggggggtccccagaa catcggcccaagcttctgctagatcttccgtcctacgtctgggaacatgatcgggtatac tggcacgagtcgcggtactccagaagtttccgcaccaatgctcagcgaccgcaccagctc ctcggaacaagacttccagatggtacggagaacgaaatccgctggaaaaattatcttcac ccgagagagctaccctggttggtccatcatcaagtcgatagacagatcgtgtttccagct gcgggctatctatcagccgtggtagaagcagtggttcaaatatacggcctcggctcgata caggttattgacctctacaaagtggtgattggccaagcgcttgtcctggaggaaaattca agtgttgagactcttttcagcttccgggtgattgaggcgtctgacattcacgtcgaggcc gtcttctccttcttttctgcgtccactaaagactcaatcagcatgtcaaagaacgcatcg ggaaatctgcgaattacactcggggctccatcgccagacgcgctgccaagcccttacaag tctgaacgcgagtttctggaagttgatccccagcgtttctacaatacggttcgtgacgtc ggactaggctacaccggtccgtttcaaaagattatcgaggcccagagaagatcgggcgag tcttcgggcatcattcaaactccagatgcagaagacgaaggcagcgctgctgcactgatc atccaccccggcacccttgactgcgccatccaatcaatcatcttggcatacagcttccct ggggatgggaggatgcgttccatataccttcccacaagtatcgaccgcctacgaattgac ccggcgggtattgtccaccacaaagggtcgtcagcgagctcgcacttgggattctttgcg tccatcacatcgaacagacccacggacctctcgggagacgttgagatccattcccaagat ggtagtaccacgctagtccagcttcagggccttcggaccacccccttgactcctgcagtt ccatcaaatgaccttcagctcttcttcaagacatcgtggcaagtggatgcgccaacgggg aatccaggtttatgggaagggggtgaaaactcctacgattatgatcttgctttcgcccag gaaagagttgcctattattacatcaggctcttgaatgaagccatcccgccatccaagagg tctgaccttgagtggtatcacaaagttttctatgagtatatcgaccacaccttggcctgg gtaaacaagggaactcatccctttgcaaagccagagtggagtaaagacactcaatatgat cttcttaagatttttgagcgattccctgacagcattgatctacgtatcatgcgagccgtc ggcaccaatctagtgtccgccatgcagaaggagatgaacatcctcgaggcgatgatgaag gacaacatgctcaatgacttctacgccacctctcttggcatgcgagaatacctgcaggac ctggctcgcatggtgggccagctgagccatcgttatccacacatgaacgttttggagatt ggtgccggcactggtggcgctacggatatgattttccaacagctccaaggatccttcgcc tcatatacatacaccgacatctccagcggtttctttgaaaacgcccaagttaaattcgat agacaccgtggaaagatgtcgttcaaggtccttgacatagaaaaggacatcatggaacag ggctacgcaccgcactcattcgacctcattatcgcctcactggtcctccacgcgacgcga gatcttgacgagaccatgcacaacgtccgcaagcttctcaagccaggtgggcgtttgatc atgctcgagatcaccgacaacgaccccattcgtttcggctttatcttcgggggccttcct ggctggtggcttggctacgaccagggaaggaagctctctccctgcgtcggcattgaggag tgggaagccctcatgttaaagactggcttctccacaatcgaggcaatcacgtctcacaat aaaacgttcccgttgcccctttcggtgatcgccacgaaagccatagatgaccgtgtcgcc ttccttcaaaatccactcgtttccggtgcggaggtaaatctagggctcgactccctcgtc attctaggaggctccacgagcaagacggccgaggtagcctcagcaattgaatctgcggtg atccgtcaatacaagagcaaacctaaacgagttctctacttggaggatatatcccagcag gacctgccattcctcgggagcctagtaagccttttggacttggaagaagagtccaccttt gagcaaatgacacctgggaagctttccgctttgcaagagatcttcaagcagaataggaca gtgttatgggtgacacgtggggccctcggcggcagcccttaccgaaacatgtacagaggc ctgcagcgaacaatggagaaggagctaaagcatctgagggttcagatgctcgactttgct tcggatgctgacgttgatggtgaaaccattgcctcgaaactcctacagctggaagccgtc aacgcatgggagcaaagcgacgacacagccaatctcctctggtacccagagaacgaagtt ttggtccagaacgctcagactctagtgccacggattcgcctggatttggaaagaaaccgg cggtacaactctgggagacgcctcattacccaagaggtgagactcggccagacagtcgtc actgtgcgacattcggggtcgaacttcgtcatcgagcagaggagtgatacgcaaacaacc gcagcccgaccaggttatgtagacgtttgccccgagtactcccttcttaagacagtcaaa ctgccgagcggagggttcctctacctatcaaccggccacgacgtcatgaccgaggaacag gttatcgccctatctgtagccctggaatctcggatccgaacccccgaaagttgggttctt cggctcaattccgaatctgaagaagagtctaagcgagtattactggggctttaccttcaa cttttgacggaaaacatcctttggggtgtcaagcctggagagtcggtggcgatcttgaac ccttgccattctctgggcaacgtcctcacacagaatagtgcggagaggggggttaatctt atcttactgaccgacgccgctgctggtagagagataacagctcggccttggacttcaatc caccctcgagccaccaagcatgccctcggaagggtgataccaagaaacttgagacgcttt atccataccaacgacaacagcgagcttatcagcgcaatcatacacgccttgcccccgaag tgtgaaatagtgaatcaacagggcttcacaagcctggaagcgagtgttggcctcacgtac tcggccgtttccgccgtgtctggccatctgaaagtggcatggacgcgatccgttctggag gttaccgtgccggaatcgcaccccttggtcggtatttcccagttagcccagcttcatgtc ccgtcaagcgctacgaaacagactttcctgtcctggtcatcgttgccatccgccccagta cagcttcggcctgccacggatgtggtacacttcgccaaagacaagacgtactggatggtt ggactcacagggagcttaggcttgtctctgtgcgagtggatggcccagcgtggcgcgaaa tacattgcgctctcgagtagaaatccgcgtgttgatgatgggtggaagcaggcaatggcg gatcttggctgcactgtccgagtctttgccaacgatgtaaccaaccgcgacgaagttttt gcccttcataaacgaatatccgagacccttcctccgattgcgggtgtagctcagggtgct atggtcctagatgacgcgctgttccccgatgtcgacattgaacggttccacaaaatcacg aagcccaaggtgaatggcagcatctatctagacgagctgttctccagcgatcaactcgaa ttcttcgtctttttttcatcggtagcttacgtcactggaaatgctggtcaaagcatttac ggcgcagcgagcgccttcatggcgagtctcgccacacagaggcgtcgaaggggcctggcc gcttccgtcatcaacatcggtgccatcctcggaaccggctacgtttccagggagctttcg ctacagcagcaggagtatctgcgtaaggtcggtctcgtatggatgtcggagcaagatgct catgaaatatttgccgagggtatcctcgccagcagggtggactcaccagacagccacgag ttcgagacgggccttcggactgacgaaggccgatctcgcgatatcgttagtgagccaccc atgctacagcatctcggcatcaagggcaatgctgcttcctcaggtggaggtattcaaacg aagcaaaatgtccagacaagagcccgactgctcgaggcgacttcacgcgaacaagtattt gagatcctaaaagagggtttcctactcaagctacaggcagctctccaagcggatccaaat aaaccaatgttggacttaagtttggacgagatcggcgcggattccttggtcgccgttgat atccgctcttggttcctcaaggaatcgggagtggatgtgccagtcctcaagatcctgaat tcatcctctgtccgggaactcctacttttcgcacatgactctgttcccaaggatgtgact ccgaacgtgcttggagactctgataactctctcaagccggcagtagtgtcagccggcgtg gccgaggcggaggatttcctacagccgaatcacaaatcaacatcggactcggatggggcc cctcaatcttcatctcaatcagataccagagactcagaggaaggggagatcacacccaga agctcagaggtgccatcggaggctgaccgagatgactttccgaagccgacgaaccctcaa gagctcacaatccccggtttcattggaaatgagaaagtcacccctgagagaatcgtccca atgtcctttggtcagtcgagattctggtttttgaaacactacgttcaggaccagacggcc tttaatatcacgacagtgattaaattacaaggtcgtttgcgcgttgatgcactggaggga gcattacgtgccgttggccaacgccacgaggcccttcgtaccctcttctttgtcgaccag aagaccaaggaacctaaacaggcaatactgcccacgtctctcttacggctcgaaaaagtc gccatttccgacgaaggagaattagccaaggcggtcttggaagcaaaacagcatatcttc gacattgagcgtggtgaagctctgcggatccaactgctatctctttcgcccacggctcac tggatcgtgcttggctatcaccatatctacatggacggaattggatacgtcgtgttcatc tctgactgggaaagggcatacaacggggttcttaatacacagccttccgatatcctacag tacccagacttttcgctgaggcagatccgagagtatcaaacgggcacatggtccgacgag ctctcgttctggcgaagccagttcccggaccttcccaacgcacttccgttattgcctgtc agtcgattgtccacccggccgatctcgtctggatttggctcctactctgctagcttcagg atcgaccgaaaccttaccgagagaattagtcaggtctgccgccagttcaaggtgacatcc ttccacctacatctcgcagtcttccatattcttctctaccgctacgcttccctgatcgat gacatgtgtatcggcatagccgatggaaatcgcaaggacgccgatgttcaaggtagtcta ggaatattcctggatctccttcccatccgtctccgtcgttcccctcaggatacctttgca aataccctcaaggacgtgcggaagaccacactcgccgcctttgggaactcacgcgttccg ttcgatgtgcttctgaatgagctaaatgtacccagagtcccgtcacatagtcctttgttc caagctttcgtgaactatcggcaaaaccatcaagagtcgcgctccttgtttggatgcgat ggcgagcttgatattatcgctaccggccaaacagactacgacgtcagcgttgatatcttg gatctgagtgccgaaggaggcgagagcgttgtatccttgggggttcagaaggatctctac gaccaacatgctgcagaagttctggccgagagttaccacgccctcctccgtcaatttacc aacaaccctgcagctagggttacctgggttactctctattctaatgagagcgttaaagat gcacttcagctcggtcgaggcactgaagcacccggaaaataccctaccattgtccatcgg atcgacgccatggtcgagaaatacccgaaccagacggccgtgaaagacgcttacgggaaa gtattcacctatcacgagctcgccggtcgagtcgacagcatcgcacagaatctcctcaga ctcgggatcggaaacacatccaacgtgggtgtgttccagacccgcagtgcggaatggatc ttctctctccttgccatcttacgtgtcggcgccgcctacgtagcgatggatgtaaacgtg ggcccggatagactatcccttatcgtggacaactgcaagccagcagccatccttgtggac tcggacacagagagcgatgcgttcgttattgctactcagtcgcagcgcccgtctacttct ccttctacctcggaagtccgtattcccatcattaacatcacagacccgcaaccctcaaat gaagtcggtactgccccgaacagcgccaggccggcagacgcagccgttatcatttactcc agcggctcaactggtgtgccaaagggagttgtcctctcgcactccaacatcgcgaattac gcagacgttgtgccacccacctggggcggtgttcgggagggtcacgagatctttttgaac caggcctcctactccttcgatgtctctctacagcaaacaatcgtggctcttggtattgga agtaccgtcgtcgttgtcggaaaccaagcgcgcggcgatccagcagccctgttgaagcta ataatcgccgagaacatcaccgtcacgggggccacgccgacggagtatctgacatgggca cgacactgggatgtggacctcctccgcaagtctcagtggcgtcatgccttcacctgggga gagcccatcacaaaacaacaggtccgagacctgcagcttctcggtcttcctaacctcaat gtcatcgacgcctatgggcctgccgaagcgaccattaccagcgcacatggacgcgtcaac ttagagcacattaagctcgagagcacaaccaggagtccaaatgtccccttgaccatcacg cctaacggttccgtttacattgtggatgagagcttgaaccctgtgccgcctggagtcttg ggcgaaattgttctcggtggcgcagccgtcgcaaaaggttatctaaacgacgagtcacta acatcagagaggtttatccaagacaaattcgccagcccttatttcaagtctaaaggctgg actactgcgcatcgcactggcgatcgcggattcttgacggcggatggcgggcttgtgttg caaggtagaattgaaggcagcacacaagtcaagttggcaggtatacgtgttgacgtccag gatgtagaggcaacgatcatccaagcagtcccagatgtcagccaggtcgtggtatcggtc cgcaggggcgcagaatctgatagcgctcctttcctcgttgctttcgttatactctccaac aatgctgccgggctccccgcagacgaaaagacacgcttcctagaggacctaccgcgaaat ctgcccctaccacagtacttgaagcccgctgtggtcgtctccgtcgaccaccttccgact aacagctctcataagctggaccgccgtttgattgatggatggccactgccgactgaagga gcacaagccacaaatcctagcggcgacgaatcttccactcttacggaatttgagcaaacg cttcgccagctctggggggacgcactccctgacggcctcgcccaacatcgctctatcggt ggctcctctgacttcttccacatcggcggcagctctctctctttgatcaatcttcagggc cttatcaaggagagactcaattttcccatttccctttacaaacttttccagaacagtacc ttgagcagcatggcggcttcacttcgaaatgagaggacagtcatcgatgaactaactgca gtcgactgggagcttgaaaccacgttgccacttgacattgttcggcaagacagtgaagaa acagagtacacaggaacagtgttgccagtcagaaatgtcgcccttaccggatctacgggg ttcatcggaaaagaaatccttcggcgtcttatagcggatgaccgcatctccaaagtgtac tgcctcgcagtgcggaagaagagatcagacctgccgcccagcctcttcggtcacgaaaaa gtagtggtatattctggtgatctcggcgcaccgcgactcggcttatccgaaacggaagtt gcggctgtttttggtacccaaggagttgctgccgatgcggtgattcacgcaggcgcggac gtctcgtttctgaaaacttaccattccctacgacttgtcaacgtcgcttcaacccgcgaa ctaatccggctcgctgctccacgccggctccctctacatttcatctcttcagctacagtg gcccgactcgcacttcaagcgggacgtacgagcttcgggcgagagtctatcgcgaactat ccccccaatgcaacacgcgcggctgtagaagacggttacgtggcagccaaatggacaagc gaggtcctcgtcgagaacgcggccaaacaactcggtcttcctgtcttcattcaccgaccg actagcgtcaccggcgaggatgctagcgatcttgaccttatgagcaacatcacgaagtat gtgcaaaagaccagaaccatcccggatacgcatgagtggaacgggggcttcgatttcgta tccgtgcagacagtcggccaggacatcgtgcgtgaggtcttggacaacgatcaggtcggc ggtgaggtgcggtatgtgttccaggcgggcgagaacgtggttgacagccacaagatgcaa tctatcctggagcttggaacggggacttcgttcgaggttttgccgtttgaccagtgggtt gatggcgcggaacaggccggactgagtcatctgttggccctctacttgagaagggccgcc aagggacagttgttaattccgaagctgttaaacgaatag

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