Salinispora arenicola: Sare_1133
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Entry
Sare_1133 CDS
T00613
Name
(GenBank) 2-isopropylmalate synthase/homocitrate synthase family protein
KO
K01649
2-isopropylmalate synthase [EC:
2.3.3.13
]
Organism
saq
Salinispora arenicola
Pathway
saq00290
Valine, leucine and isoleucine biosynthesis
saq00620
Pyruvate metabolism
saq01100
Metabolic pathways
saq01110
Biosynthesis of secondary metabolites
saq01210
2-Oxocarboxylic acid metabolism
saq01230
Biosynthesis of amino acids
Module
saq_M00432
Leucine biosynthesis, 2-oxoisovalerate => 2-oxoisocaproate
Brite
KEGG Orthology (KO) [BR:
saq00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00620 Pyruvate metabolism
Sare_1133
09105 Amino acid metabolism
00290 Valine, leucine and isoleucine biosynthesis
Sare_1133
Enzymes [BR:
saq01000
]
2. Transferases
2.3 Acyltransferases
2.3.3 Acyl groups converted into alkyl groups on transfer
2.3.3.13 2-isopropylmalate synthase
Sare_1133
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Paralog
Gene cluster
GFIT
Motif
Pfam:
HMGL-like
LeuA_dimer
HCS_D2
Motif
Other DBs
NCBI-ProteinID:
ABV97041
UniProt:
A8M5G7
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All DBs
Position
1283032..1284615
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AA seq
527 aa
AA seq
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MTFQVYDTTLRDGAQREGVSYSVVDKLAVARLLDEFGVGFIEGGWPGAVPKDTEFFRRAR
TDLDLNHAVLVAFGATRRAGLGVDNDPQVHSLLAAETPVVTLVAKADLRHVQRALRTTAD
ENLAMIHDTVTYLVAEGRRVFVDGEHFFDGYRDDPTYTSSVVEAALAAGAERFVLCDTNG
GMLPSQVTAVIADLTARLGVAPEQLGIHGQDDTACAVANTIAAVEAGVRHVQGTANGYGE
RPGNADLFAVVANLQLKLGLPVLPAGCLERMVRVSRGIADIANIAPDDHQAYVGAAAFAH
KAGLHASAIKVDPLFYNHVDPQAVGNHMRILVTEMAGRASIELKSRELGLALADHPEALN
RVTKRVKDLEAAGWSFEAADASFELLVRSELPDGAPARPFTLESYRILVEHREDNAVVSE
ATVKIRIGGERMIATAEGNGPVNALDEALRVGLARHYPELRDFELADYKVRILEGSHGTG
AVTRVLVETADGAGRDWTTVGVHPNVVEASWGALVDALTYGLDRART
NT seq
1584 nt
NT seq
+upstream
nt +downstream
nt
atgacgttccaggtatacgacacgaccctgcgcgacggcgcccagcgtgagggggtcagc
tattcggtcgtcgacaaactcgcggtggcccggcttctcgacgagttcggcgtcggtttc
atcgaaggaggatggccgggcgcagtaccgaaggacaccgagttcttccgtcgcgcgcgc
accgacctcgacctgaaccacgcggtgctggtggccttcggcgccacccgtcgcgccggt
ctgggcgtcgacaacgacccgcaggtgcacagcctgctcgccgccgagacccccgtcgtc
acgctggtcgccaaggccgacctgcggcacgtgcagcgggccctgcgtaccaccgcggac
gagaacctggcgatgatccatgacaccgtgacgtacctggtggccgagggccggcgggtg
ttcgttgacggggagcacttcttcgacggctaccgtgacgatcccacgtacacctcgtcg
gtggtcgaggccgcgctcgccgccggtgcggagcggttcgtgctgtgcgacaccaatggt
ggcatgcttccgtcccaggtcaccgccgtgatcgctgacctcaccgcccgactcggcgtg
gcacccgagcaactcggcatccacggccaggacgacaccgcctgtgccgtggcgaacacc
atcgccgcggtggaggcgggcgtacggcacgtgcagggcaccgccaacgggtacggcgag
cgacccggtaacgccgacctcttcgcggtggtggcgaaccttcaactcaagctcgggctg
ccagtcctaccagcgggctgcctggaacggatggtgcgggtgtcccgcggcatcgccgac
atcgccaacatcgcacccgacgaccaccaggcgtacgtcggtgccgcggccttcgcccac
aaggcggggctgcacgcgagcgcgatcaaggtggatccgttgttctacaaccatgtggac
ccgcaggcggtgggaaaccacatgcgcattctcgtcaccgagatggccggacgggccagc
atcgaactcaagagccgcgagctgggtctcgcactggccgaccacccggaggccctgaac
cgggtcaccaagcgggtcaaggacctggaggccgccggctggtcgttcgaggcggcggat
gcctccttcgaacttctggtccgctccgaactgcccgacggggcgccggcgcgaccgttc
accctcgagtcctaccgcatcctggtcgagcaccgggaggacaacgcggtggtctccgag
gcgacggtaaagatccggataggcggtgagcggatgatcgccaccgcggagggcaacggc
ccggtgaacgcgctcgacgaggcgttacgcgtcggcctcgcccggcactatccggagctg
cgtgacttcgagttggccgactacaaggtgaggattctggagggcagccacggcaccggg
gcggtgaccagggtgctggtggagacggccgatggggccggccgggactggaccacggtg
ggcgtgcatcccaacgtggtggaggcgagttggggcgcactggtcgacgccctgacctac
gggctggatcgggcccggacctga
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