Streptomyces aquilus: EJC51_16615
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Entry
EJC51_16615 CDS
T07011
Symbol
leuA
Name
(GenBank) 2-isopropylmalate synthase
KO
K01649
2-isopropylmalate synthase [EC:
2.3.3.13
]
Organism
saqu
Streptomyces aquilus
Pathway
saqu00290
Valine, leucine and isoleucine biosynthesis
saqu00620
Pyruvate metabolism
saqu01100
Metabolic pathways
saqu01110
Biosynthesis of secondary metabolites
saqu01210
2-Oxocarboxylic acid metabolism
saqu01230
Biosynthesis of amino acids
Module
saqu_M00432
Leucine biosynthesis, 2-oxoisovalerate => 2-oxoisocaproate
Brite
KEGG Orthology (KO) [BR:
saqu00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00620 Pyruvate metabolism
EJC51_16615 (leuA)
09105 Amino acid metabolism
00290 Valine, leucine and isoleucine biosynthesis
EJC51_16615 (leuA)
Enzymes [BR:
saqu01000
]
2. Transferases
2.3 Acyltransferases
2.3.3 Acyl groups converted into alkyl groups on transfer
2.3.3.13 2-isopropylmalate synthase
EJC51_16615 (leuA)
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GFIT
Motif
Pfam:
HMGL-like
IPMS_D2
LeuA_dimer
Motif
Other DBs
NCBI-ProteinID:
AZP17591
UniProt:
A0A3S9HZQ6
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All DBs
Position
complement(3609614..3611335)
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AA seq
573 aa
AA seq
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MANRQQPSSMPIHKYGQYDQVDIPDRTWPDNRITVAPRWLSTDLRDGNQALIDPMSPERK
RRMFDQLVKMGYKEIEVGFPASGQTDFDFVRSIIEEPGAIPDDVTISVLTQAREDLIERT
VESLKGAKRATVHLYNATAPVFRRVVFRGSKDDIKQIAVDGTRLVMEYAEKLLGPETEFG
YQYSPEIFTDTELDFALEVCEAVMDVYQPGPGREIILNLPATVERSTPSTHADRFEWMHR
NLSRREYVCISVHPHNDRGTAVAAAELALMAGADRVEGCLFGQGERTGNVDLVTLGMNLF
SQGVDPQIDFSDIDEIRRVWEYCNQMEVHPRHPYVGDLVYTSFSGSHQDAIKKGFDAMEA
DAAAKGVTVDDIEWAVPYLPIDPKDVGRSYEAVIRVNSQSGKGGIAYVLKNDHKLDLPRR
MQIEFSKIIQAKTDAEGGEVTGSDIWATFQDEYLPNPENPWGRIQVKNGQSTTDTDGVDT
LKVEATVDGVDTVLTGTGNGPISAFFDALAKVDIDARLLDYQEHTMSEGASAQAASYIEC
AIDGKVLWGIGIDANTTRASLKAVVSAVNRAAR
NT seq
1722 nt
NT seq
+upstream
nt +downstream
nt
atggcgaaccgccagcagcccagcagcatgccgatccacaagtacggccagtacgaccag
gtcgacatcccggaccgcacctggccggacaaccggatcaccgtcgccccccgctggctc
tccaccgacctgcgtgacggcaaccaggccctgatcgaccccatgtcgcccgagcgcaag
cgccggatgttcgaccagctggtcaagatgggctacaaggagatcgaggtcggcttcccg
gcctccggccagacggacttcgacttcgtacgctcgatcatcgaggagcccggggcgatc
ccggacgacgtcaccatctccgtgctgacccaggcccgcgaggacctgatcgagcggacc
gtggagtccctgaagggcgccaagcgcgcgaccgtccacctgtacaacgcgacggctccc
gtcttccgccgggtcgtcttccgcggctccaaggacgacatcaagcagatcgccgtcgac
ggcacccgcctggtcatggagtacgccgagaagctgctgggccccgagaccgagttcggc
taccagtacagccccgagatcttcaccgacaccgagctggacttcgccctggaggtctgc
gaggcggtcatggacgtctaccagccgggcccgggccgcgagatcatcctcaacctgccc
gccacggtggagcgttcgacgccgtccacgcacgcggaccgcttcgagtggatgcaccgc
aacctgtcccgccgcgagtacgtctgcatctccgtccacccgcacaacgaccgcggtacg
gccgtcgccgccgccgagctggcgctgatggccggcgccgaccgcgtcgagggctgtctg
ttcgggcagggcgagcgcaccggcaacgtcgacctggtcaccctgggcatgaacctgttc
tcccagggcgtcgacccccagatcgacttctccgacatcgacgagatccgtcgcgtgtgg
gagtactgcaaccagatggaggtccacccgcgccacccgtacgtgggcgacctggtctac
acgtccttctccggctcccaccaggacgccatcaagaagggcttcgacgcgatggaggcc
gacgcggccgccaagggcgtcaccgtcgacgacatcgagtgggcggtgccgtacctgccc
atcgaccccaaggacgtcggccgctcctacgaggcggtcatccgggtcaactcgcagtcc
ggcaagggcggtatcgcgtacgtcctgaagaacgaccacaagctggacctgccgcgccgg
atgcagatcgagttctcgaagatcatccaggccaagacggacgccgagggcggcgaggtc
acgggctcggacatctgggcgaccttccaggacgagtacctgccgaaccccgagaacccg
tggggccgtatccaggtcaagaacgggcagtcgacgaccgacacggacggtgtggacacg
ctgaaggtggaggccacggtggatggtgtcgacaccgtcctgaccggtaccggcaacggt
ccgatctcggccttcttcgacgcgctggccaaggtcgacatcgacgcgcggctgctggac
taccaggagcacacgatgagtgagggtgcgtccgcgcaggccgcgtcgtacatcgaatgt
gcgatcgacggcaaggttctgtgggggatcgggatcgatgcgaacacgacacgtgcgtcg
ctgaaggcggttgtgtccgctgttaacagggctgcgcgctga
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