Staphylococcus aureus subsp. aureus MRSA252 (MRSA): SAR1749
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Entry
SAR1749 CDS
T00182
Symbol
hemD
Name
(GenBank) uroporphyrinogen III synthase
KO
K01719
uroporphyrinogen-III synthase [EC:
4.2.1.75
]
Organism
sar
Staphylococcus aureus subsp. aureus MRSA252 (MRSA)
Pathway
sar00860
Porphyrin metabolism
sar01100
Metabolic pathways
sar01110
Biosynthesis of secondary metabolites
sar01120
Microbial metabolism in diverse environments
sar01240
Biosynthesis of cofactors
Module
sar_M00926
Heme biosynthesis, bacteria, glutamyl-tRNA => coproporphyrin III => heme
Brite
KEGG Orthology (KO) [BR:
sar00001
]
09100 Metabolism
09108 Metabolism of cofactors and vitamins
00860 Porphyrin metabolism
SAR1749 (hemD)
Enzymes [BR:
sar01000
]
4. Lyases
4.2 Carbon-oxygen lyases
4.2.1 Hydro-lyases
4.2.1.75 uroporphyrinogen-III synthase
SAR1749 (hemD)
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Gene cluster
GFIT
Motif
Pfam:
HEM4
IMS_HHH
Motif
Other DBs
NCBI-ProteinID:
CAG40740
UniProt:
A0A7U7IDI1
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All DBs
Position
complement(1811978..1812646)
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AA seq
222 aa
AA seq
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MKPVVVMTQTNDMQSDLVSIIHKPFIDIKPLNFDIHLLNQRYDWLIFSSKNAVKFFYKYL
KGINVDNIAVIGSKTAQYCESLGIRVDFMPNDFSQEGFLESFNQTNQKILLPSSELARPL
LSAALSEDNEVVKIDLYTSVPNKQNIQDVKEMIEHQQIDALTFSSSSAVRYYFNEGFVPK
FKSYFAIGEQTARTIKSYQQPVTIAEIQTLESLIEKILESRG
NT seq
669 nt
NT seq
+upstream
nt +downstream
nt
atgaagccagttgtagttatgacacaaacaaatgacatgcaaagtgatttagtatcaatt
attcacaaaccttttattgatataaagccactaaattttgatattcatttgttaaatcaa
cgctatgactggcttattttttcatctaaaaatgctgtgaaattcttttataaatatcta
aaaggaattaatgttgataacattgctgtgataggaagtaagacagcgcaatattgtgaa
tcacttggcattcgagttgattttatgccaaacgacttttctcaagaaggatttttagaa
tcatttaatcaaactaaccaaaaaatacttttgccttcgagtgaattggcgagaccattg
ttatcagcagcgttatctgaagataatgaagttgttaaaatagatttatatacttcagtg
cctaacaaacaaaatatacaagatgttaaagaaatgatagaacatcaacaaatcgatgca
ttaacattttcaagttcgtcggcagtacgttattattttaatgaaggatttgtaccaaaa
ttcaagtcgtattttgctattggagaacaaacagcacggaccattaaatcatatcaacag
ccagtaacaattgcagaaattcaaacactcgaatcactaattgaaaagattttagaaagt
aggggctaa
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