Sorex araneus (European shrew): 101540816
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Entry
101540816 CDS
T07854
Symbol
ERBB2
Name
(RefSeq) receptor tyrosine-protein kinase erbB-2
KO
K05083
receptor tyrosine-protein kinase erbB-2 [EC:
2.7.10.1
]
Organism
sara
Sorex araneus (European shrew)
Pathway
sara01521
EGFR tyrosine kinase inhibitor resistance
sara01522
Endocrine resistance
sara01524
Platinum drug resistance
sara04010
MAPK signaling pathway
sara04012
ErbB signaling pathway
sara04020
Calcium signaling pathway
sara04066
HIF-1 signaling pathway
sara04151
PI3K-Akt signaling pathway
sara04510
Focal adhesion
sara04520
Adherens junction
sara04530
Tight junction
sara05200
Pathways in cancer
sara05205
Proteoglycans in cancer
sara05206
MicroRNAs in cancer
sara05212
Pancreatic cancer
sara05213
Endometrial cancer
sara05215
Prostate cancer
sara05219
Bladder cancer
sara05223
Non-small cell lung cancer
sara05224
Breast cancer
sara05226
Gastric cancer
sara05230
Central carbon metabolism in cancer
Brite
KEGG Orthology (KO) [BR:
sara00001
]
09130 Environmental Information Processing
09132 Signal transduction
04010 MAPK signaling pathway
101540816 (ERBB2)
04012 ErbB signaling pathway
101540816 (ERBB2)
04066 HIF-1 signaling pathway
101540816 (ERBB2)
04020 Calcium signaling pathway
101540816 (ERBB2)
04151 PI3K-Akt signaling pathway
101540816 (ERBB2)
09140 Cellular Processes
09144 Cellular community - eukaryotes
04510 Focal adhesion
101540816 (ERBB2)
04520 Adherens junction
101540816 (ERBB2)
04530 Tight junction
101540816 (ERBB2)
09160 Human Diseases
09161 Cancer: overview
05200 Pathways in cancer
101540816 (ERBB2)
05206 MicroRNAs in cancer
101540816 (ERBB2)
05205 Proteoglycans in cancer
101540816 (ERBB2)
05230 Central carbon metabolism in cancer
101540816 (ERBB2)
09162 Cancer: specific types
05212 Pancreatic cancer
101540816 (ERBB2)
05226 Gastric cancer
101540816 (ERBB2)
05219 Bladder cancer
101540816 (ERBB2)
05215 Prostate cancer
101540816 (ERBB2)
05213 Endometrial cancer
101540816 (ERBB2)
05224 Breast cancer
101540816 (ERBB2)
05223 Non-small cell lung cancer
101540816 (ERBB2)
09176 Drug resistance: antineoplastic
01521 EGFR tyrosine kinase inhibitor resistance
101540816 (ERBB2)
01524 Platinum drug resistance
101540816 (ERBB2)
01522 Endocrine resistance
101540816 (ERBB2)
09180 Brite Hierarchies
09181 Protein families: metabolism
01001 Protein kinases [BR:
sara01001
]
101540816 (ERBB2)
09183 Protein families: signaling and cellular processes
04147 Exosome [BR:
sara04147
]
101540816 (ERBB2)
04090 CD molecules [BR:
sara04090
]
101540816 (ERBB2)
Enzymes [BR:
sara01000
]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.10 Protein-tyrosine kinases
2.7.10.1 receptor protein-tyrosine kinase
101540816 (ERBB2)
Protein kinases [BR:
sara01001
]
Receptor tyrosine kinases (RTK)
EGFR family [OT]
101540816 (ERBB2)
Exosome [BR:
sara04147
]
Exosomal proteins
Exosomal proteins of breast cancer cells
101540816 (ERBB2)
CD molecules [BR:
sara04090
]
Proteins
101540816 (ERBB2)
BRITE hierarchy
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
PK_Tyr_Ser-Thr
Recep_L_domain
GF_recep_IV
Pkinase
Furin-like
TM_ErbB1
Haspin_kinase
Kinase-like
DUF5316
CD34_antigen
Motif
Other DBs
NCBI-GeneID:
101540816
NCBI-ProteinID:
XP_004608792
LinkDB
All DBs
Position
Unknown
AA seq
1224 aa
AA seq
DB search
MKLRRPASPETHLHMLRHLYLGCQVVQGNLELTYLPASANLSFLQDIQEVQGYVLIARSR
VSRVPLQRLRIVRGTQLFEDKYALAVLENGDLQDTAEGGLRELQLRNLTEILKGGVLIQR
NPHLCHQDTILWEDIFHKKNELAQQLIDSNRSRTCKPCSPTCKTSGCWGESSEDCQILTR
TVCASGCARCKGPLSTDCCHEQCAAGCTGPKHSDCLACLNFNHSSICEQLCPTLVTYNTD
TFESMLNPEGRYTFGASCVTACPYNYLSTDVGSCTLVCPMDSQEVTASDGTQRCEKCSKP
CAPVCYGLGMEHLREVRAVTSANIQMFAGCKKIFGSLAFLRESFEGDSASGTAPLQPEQL
HVFESLEEITGFLYISAWPDSLPDLGVFQNLRVIRGRILHDGAYSLTVQGLGIRWLGLRS
LRELGSGMALVHRNPHLCFIHTVPWEQLFRNPHQTLLRSANRPVDECEGEGLGCYPLCAQ
GHCWGPGPTQCVNCSQFLRGQECVEECRVLQGSPPEYVKDRRCLPCHAECQPQNGSITCF
GSEADECVACAHYKDPPFCVARCPSGVKPDLSFMPIWKFPDEERMCQPCPINCTHSCVDL
DDKGCPAEPRASPVTSIIATVVGILLFLLVCLVSGIFIKRRRQKIRKYTMRRLLQETELV
EPLTPSGAVPNQAQMRILKETELRKVKVLGSGAFGTVYKGIWIPDGENVKIPVAIKVLRE
NTSPKANKEILDEAYVMAGVGSPYVSRLLGICLTSTVQLVTQLMPYGCLLDHVREHRGRL
GSQDLLNWCVQIAKGMSYLEEVRLVHRDLAARNVLVKSPNHVKITDFGLARLLDIDETEY
HADGGKVPIKWMALESILRRRFTHQSDVWSYGVTVWELMTFGAKPYDGIPAREIPDLLEK
GERLPQPPICTIDVYMIMVKCWMIDSECRPRFRELVAEFSRMARDPQRFVVIQNEDLGPA
SPLDSTFYRSLLEDDDMGDLVDAEEYLVPQQGFFCPDPAPGTGGTAHRRHRSSSTRSGGG
GELTLGLEPAEEEPPRSPLAPSEGAGSDVFDGDLGMGAAKGQQSLPTHDLSPLQRYSEDP
TAPLPPETDGYVAPLTCSPQPEYVNQLEVWAQPPSPLAAPLSPARPAGATLERPRTLSPK
TLSPGKNGVVKDVFAFGGAVENPEYLAPRGGVAPQPHPPPGFSPAFDNLYYWDQDPSERG
SPPATFEGTPTAENPEYLGLDVTV
NT seq
3675 nt
NT seq
+upstream
nt +downstream
nt
atgaagctgcggcggcccgccagtcccgagacccacctgcacatgctccgccacctctac
ctcggctgccaggtggtgcagggcaacctggagctcacctacctgcccgccagcgccaac
ctctccttcctgcaggacatccaggaggtgcaaggctacgtgctcattgctcgcagccgg
gtgagccgggtgcctctgcagcggctgaggatcgtgcgcggcactcagctctttgaggac
aagtatgccctggcggtgctggaaaacggggacctgcaggacaccgccgagggaggactg
cgtgagctgcagcttcggaacctcacagagatcctgaaaggaggggtcctgatccagcgg
aacccccatctgtgccatcaggacacgattttgtgggaggacattttccacaagaagaat
gagctagcgcagcagctgatagacagcaaccgatctcgcacgtgcaaaccctgttctccc
acctgcaaaacctctggttgctggggagaaagttctgaggattgtcagattctgacgcgg
acggtctgcgccagtggctgtgcccgctgcaaaggcccgctgtccaccgactgttgccac
gagcagtgtgcggccggctgcacaggccccaagcactccgactgcctggcctgcctcaac
ttcaaccacagcagcatctgtgagcagctctgcccgacactggtcacctacaacacggac
accttcgagtccatgctcaaccccgagggccgctataccttcggcgccagctgcgtgact
gcctgtccctacaactacctgtctacggacgtgggctcctgcaccctggtctgcccgatg
gacagtcaggaggtgacagctagtgacggaacccagcggtgtgagaaatgcagcaagccc
tgtgctccagtgtgctatggtctgggcatggagcacctgcgggaggtgagggctgtcacc
agtgccaacatccagatgtttgcgggctgcaagaagatcttcgggagtctggcgtttctt
cgggagagctttgagggggactcggcctccggcacggcccccctccagcccgagcagctc
cacgtcttcgagagtctggaggagatcacaggtttcctgtacatctctgcctggccggac
agcctgcctgacctcggcgttttccagaatctccgtgtcatccgaggacgaatcctgcat
gacggcgcctactccctcaccgtgcaaggcctgggcatccgctggctggggctgcgctcg
ctgcgggagctgggcagcgggatggcccttgtccaccgcaacccccacctctgcttcatc
cacacggtgccctgggaacagctcttccggaacccccaccagactctgctccgcagtgcc
aaccggcctgtggatgagtgtgagggcgagggcctgggctgctaccctctgtgtgcccag
gggcactgctggggcccggggcccacccagtgtgtcaactgcagccagttcctccggggt
caggagtgcgtggaggagtgccgagtcctgcaggggtcccccccggagtacgtgaaggac
aggcgctgcctgccgtgccacgctgagtgccagccgcagaacggctccatcacctgcttt
ggctcagaggcagatgagtgcgtggcctgtgcccactacaaggaccctcccttctgcgtg
gcccgctgccccagcggcgtgaaacctgacctctccttcatgcccatatggaagtttccc
gatgaggagcgcatgtgccagccatgccccatcaactgcacccactcctgtgtggacctg
gatgacaagggctgccccgctgagccgagagccagccccgtgacgtccatcatcgccacc
gtggtgggcatcctgctctttctgctcgtgtgtctggtctcgggcatcttcatcaagcgc
cggcggcagaagatccgcaagtacaccatgcgcaggctgctgcaggagaccgagctggtg
gagccgctgacgcccagcggggcggtgcccaaccaggctcagatgcggatcctgaaagaa
acggagctgaggaaggtgaaggtgctgggatccggagccttcggcaccgtctacaaggga
atctggattcccgacggagaaaatgtgaaaatcccagtggccatcaaagtactgcgggag
aacacgtctcccaaagccaacaaagaaatcctggacgaggcgtatgtgatggccggtgtg
ggctctccgtatgtgtcccgcctgctgggcatctgcctgacgtccacggtgcagctggtc
acacagctcatgccctacggctgcctcctagaccacgtgcgggaacaccgcgggcgcctg
ggctcccaggacctgctcaattggtgtgtgcagatcgccaaggggatgagttacctggag
gaagtgcggctcgtgcatagggacctggctgcccgcaacgtgctggtcaagagccccaac
cacgtcaagatcacggactttgggctggctcggctgctggacatcgatgagacagagtac
cacgcggatgggggcaaggtacccatcaagtggatggccctcgagtccattctccgccgg
cgcttcacccaccagagtgatgtgtggagctatggtgtgactgtgtgggagttgatgacc
ttcggggccaagccttacgatgggatcccggcccgggagattccagacctgctggagaag
ggggaacggctgccccagccccccatctgcaccattgatgtctacatgatcatggtcaaa
tgctggatgatagactcggaatgccggccacggttccgggagttggtggccgaattctca
cgcatggccagggacccccagcgctttgtggtcatccagaatgaagacctgggccccgcc
agccccttggacagcaccttctaccgctccctgctggaagatgatgacatgggggacctg
gtggacgctgaggagtacctggtaccccagcagggcttcttctgccccgaccctgccccg
ggcacggggggcactgctcaccgccggcaccgcagctcctccaccaggagcggcggtggt
ggtgagctgacgttggggctggagcccgcggaggaggagccccccaggtctcccctggcc
ccctcagaaggggccggctccgatgtgttcgatggtgacttgggaatgggggcagccaag
gggcagcagagcctccctacacacgacctcagccctctacagcggtacagcgaggaccct
acggcacccctgccccccgagaccgatggctacgttgcccccctcacttgcagcccccag
ccggaatacgtgaaccagctggaggtctgggcgcagcccccctcgcccttagctgcaccc
ctgtctcctgctcgacctgctggggccactctggaaaggcccaggactctgtcccccaag
acactctcccctgggaagaatggggttgtcaaagacgtttttgccttcgggggtgctgtg
gagaatcccgagtacttggcacctcggggtggggttgcccctcagcctcaccctcctccc
ggctttagcccggccttcgacaacctctattactgggaccaggacccatcagagcggggc
tccccaccggccacctttgaggggacccctacagctgagaaccccgagtacctgggtctg
gatgtgactgtgtga
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integrated database retrieval system
