Sorex araneus (European shrew): 101542148
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Entry
101542148 CDS
T07854
Symbol
PDE8B
Name
(RefSeq) high affinity cAMP-specific and IBMX-insensitive 3',5'-cyclic phosphodiesterase 8B isoform X1
KO
K18437
high affinity cAMP-specific and IBMX-insensitive 3',5'-cyclic phosphodiesterase 8 [EC:
3.1.4.53
]
Organism
sara
Sorex araneus (European shrew)
Pathway
sara00230
Purine metabolism
sara01100
Metabolic pathways
sara04927
Cortisol synthesis and secretion
sara04934
Cushing syndrome
sara05032
Morphine addiction
Brite
KEGG Orthology (KO) [BR:
sara00001
]
09100 Metabolism
09104 Nucleotide metabolism
00230 Purine metabolism
101542148 (PDE8B)
09150 Organismal Systems
09152 Endocrine system
04927 Cortisol synthesis and secretion
101542148 (PDE8B)
09160 Human Diseases
09165 Substance dependence
05032 Morphine addiction
101542148 (PDE8B)
09167 Endocrine and metabolic disease
04934 Cushing syndrome
101542148 (PDE8B)
Enzymes [BR:
sara01000
]
3. Hydrolases
3.1 Acting on ester bonds
3.1.4 Phosphoric-diester hydrolases
3.1.4.53 3',5'-cyclic-AMP phosphodiesterase
101542148 (PDE8B)
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
PDEase_I
PDE8A_N
PAS_9
PAS
PAS_3
PAS_4
PAS_8
JetB
DHH
Motif
Other DBs
NCBI-GeneID:
101542148
NCBI-ProteinID:
XP_004613195
LinkDB
All DBs
Position
Unknown
AA seq
706 aa
AA seq
DB search
MRLTQDPIQVLLIFAKEDSQSDGFWWACDRAGYRCNIARTPESALECFLDKHHEIIVIDH
RQTRNFDAEAVCRSIRATNPSEHTVILAVVSQASGDHEEASVLPLLHAGFNRRFMENSSI
IACYNELIQIEHGEVRSQFKLRACNSVFTALDHCHEAIEITSDDHVIQYVNPAFERMMGY
HKGELLGKELAELPKSDKNRADLLDTINTCIKKGKEWQGVYYARRKSGDSIQQHVKITPV
IGQGGKIRHFVSLKKLCCTTDSNKQIHKVHRDSGDNSQTESHSFRHKNRRKESIDVKSIS
SRGSDAPSLQNRRYPSMARIHSMTIEAPITKDGLRRLSGNEYVFTKNVHQSHSHLAMPLT
INDVPPSIAQLLDNEESWEFNIFELEAVTHKRPLVYLGLKVFSRFGVCEFLHCTETTLRA
WLQVIEANYHSSNAYHNSTHAADVLHATAFFLGKERVKGSLDQLDEVAALIAATVHDVDH
PGRTNSFLCNAGSELAVLYNDTAVLESHHTALAFQLTVKDAKCNIFKNMDRNHYRTLRQA
IIDMVLATEMTKHFEHVNKFVNSINKPLAAEIEGSDCECNLVGKNFPENQMLIKRMMIKC
ADVANPCRPLDLCIEWAGRISEEYFAQTDEEKRQGLPVVMPVFDRNTCSIPKSQISFIDY
FITDMFDAWDAFAHLPALMQHLADNYKHWKTLDDLKCKSLRLPSDN
NT seq
2121 nt
NT seq
+upstream
nt +downstream
nt
atgagactgacgcaggatccaattcaggttttgctgatctttgccaaggaagatagtcag
agtgacggattctggtgggcctgtgacagagctggttatagatgcaatattgctcggacg
ccagagtcagccctggagtgctttctcgataaacaccatgaaattattgtcatcgatcac
agacaaactcgtaacttcgatgcggaagcagtgtgcaggtcgatccgggccacgaatccc
tctgagcacacggtgatccttgcagtggtttcacaagcatcgggtgaccatgaagaggcc
tccgttcttcctctgctgcacgcgggcttcaacaggagatttatggagaatagcagcata
attgcttgctataatgaactgattcaaatagaacatggggaagttcgctcacagttcaaa
ttacgggcctgtaattcagtgtttacagcattagaccattgtcatgaagccatagaaatt
acaagtgatgaccacgtgattcagtatgtcaacccggccttcgagagaatgatgggctac
cacaaaggcgagctcctggggaaggaactggctgagcttcccaagagcgacaagaaccga
gcagacctcctcgacaccatcaacacgtgcatcaagaagggcaaggagtggcagggggtt
tactatgccagacggaagtccggggacagcatccagcagcacgtgaagatcaccccagtg
attggccaaggagggaaaattaggcattttgtctccctcaagaaactgtgttgtaccact
gacagtaataagcagattcacaaggtccatcgggactcaggagacaactcccagacagag
tctcactcattccgacacaagaacaggaggaaagaatccattgatgtgaagtctatatcc
tctcgaggcagtgatgcacccagcctgcagaatcggcgctacccttccatggccaggatc
cactccatgaccatagaggctcccatcacgaaggatggcttgaggaggctgtcagggaac
gagtatgtgttcactaagaatgtgcaccagagccacagtcacctggcgatgccgctgacc
atcaacgacgtgccccccagtattgcccagctcctcgataacgaggaaagctgggagttc
aacatcttcgagttggaagctgtcacacataaaagaccattggtttacctgggcttaaag
gtcttttcccggtttggggtgtgtgaatttttacactgtactgaaactactctccgagcc
tggctccaagtgattgaagccaactaccattcctccaatgcgtaccataactctacccac
gccgccgacgtcctgcatgccacagccttcttccttgggaaggaaagagtgaagggaagc
cttgatcaactggacgaggtggcggctctgatcgcagccacggtgcacgatgtcgaccac
ccaggacggaccaactcattcctgtgcaacgcaggcagcgagctggctgtgctctacaac
gacacggccgtgctggagagccaccacaccgcgctggccttccagctgaccgtcaaggac
gccaagtgcaacattttcaaaaacatggacaggaaccattatcggacattacgccaagct
attatcgacatggtgttagccacggagatgacaaagcactttgaacatgtgaacaaattt
gtgaacagcatcaacaagcccctggccgctgagattgagggcagcgactgtgaatgcaac
ctcgttgggaagaactttcccgaaaaccaaatgctgatcaaacgcatgatgattaaatgt
gctgatgttgccaacccctgccgcccgttggacttatgcatcgagtgggctgggaggatc
tccgaggagtatttcgctcagaccgacgaagagaagagacaggggcttcctgtggtgatg
ccagtgtttgaccggaatacctgtagcatccccaagtcccagatctcctttatcgactac
ttcataaccgacatgttcgatgcctgggatgcctttgcacacttgcctgctctgatgcaa
catttggctgataattacaaacactggaagacgttggatgacctgaagtgcaagagtctg
aggcttccatctgacaactga
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