Sorex araneus (European shrew): 101542520
Help
Entry
101542520 CDS
T07854
Symbol
DOT1L
Name
(RefSeq) histone-lysine N-methyltransferase, H3 lysine-79 specific
KO
K11427
[histone H3]-lysine79 N-trimethyltransferase [EC:
2.1.1.360
]
Organism
sara
Sorex araneus (European shrew)
Pathway
sara00310
Lysine degradation
sara01100
Metabolic pathways
sara05202
Transcriptional misregulation in cancer
Brite
KEGG Orthology (KO) [BR:
sara00001
]
09100 Metabolism
09105 Amino acid metabolism
00310 Lysine degradation
101542520 (DOT1L)
09160 Human Diseases
09161 Cancer: overview
05202 Transcriptional misregulation in cancer
101542520 (DOT1L)
09180 Brite Hierarchies
09182 Protein families: genetic information processing
03036 Chromosome and associated proteins [BR:
sara03036
]
101542520 (DOT1L)
Enzymes [BR:
sara01000
]
2. Transferases
2.1 Transferring one-carbon groups
2.1.1 Methyltransferases
2.1.1.360 [histone H3]-lysine79 N-trimethyltransferase
101542520 (DOT1L)
Chromosome and associated proteins [BR:
sara03036
]
Eukaryotic type
Histone modification proteins
HMTs (histone methyltransferases)
HKMTs (histone lysine methyltransferases)
101542520 (DOT1L)
HMT complexes
Dot1-containing complex
101542520 (DOT1L)
BRITE hierarchy
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
DOT1
HALZ
Motif
Other DBs
NCBI-GeneID:
101542520
NCBI-ProteinID:
XP_004615006
LinkDB
All DBs
Position
Unknown
AA seq
1688 aa
AA seq
DB search
MADDARRPNRSPDSAHYGHLAPPTETPDCSLSSNHAHEVRPRSPVSSERPIVGRGLQWAG
ASDKHHDAAHEIIETIRWVCEEIPDLKLAMENYVLIDYDTKSFESMQRLCDKYNRAIDSI
HQLWKGTTQPMKLNTRPSNGLLRHILQQVYNHSVTDPEKLNNYEPFSPEVYGETSFDLVA
QMIDEIKMTEDDLFVDLGSGVGQVVLQVAAATNCRHHYGVEKADIPAKYAETMDREFRKW
MKWYGKKHAEYTLERGDFLSEEWRERIANTSVIFVNNFAFGPEVDHQLKERFANMKEGGR
IVSSKPFAPLNFRINSRNLSDIGTIMRVVELSPLKGSVSWTGKPVSYYLHTIDRTILENY
FSSLKNPKLRDSGAEEEKAGATTVKKPSPSKARKKKLNKKGRKMAGRKRGRPKKLSASHP
ERKPRKGQTPLELLHAQAEPPPASPSPQDAYKSPHSPFYQLPPSVQRQPPDQLLLAPTPP
ALQKLLESFKVQYLQFLAYTKTPQYKANLQQLLDQEKEKNARLLGAAQQLLGHCQAQKDE
IRRLFQQKLDELGVKALTYNDLIQAQKEISAHNRQLREQTEQLEKDTRALRGQSLQLLKA
RCEELKLDWSTLSLETLLKEKQALRSQISEKQRRCLELQISIVELEKNQRRQELLQLKSC
GPPDEGLGPQPGRLPPELDASKFSLAPFSGLSPELSLNGHAAGYELCGALSRPPSKQNTP
QYLASPLDQEVVPCTPSHGGRPRLDKLTGLALPDYTRLSPAKLVLRRHLSQEPAAGTKAS
SELHPRAEHAKETGSPGLANGMKLSPQDPWPASPGALPTAGEKGSEKGVKERGSSSSGEA
ITSLPVSIPLSTVQPSKLPVSIPLASVVLPSRAEKVSRSTPSPVPQAREASTLDKGGAGS
KGLAQVPAGFYAGSVAISGALAGSPASLVPGADPSTFDESSSSGSLFATMGSRSSTPQHP
PLLAQSRGAGSISPAHQLCTSPRLGGALQGPLPDPGKGELPAEASCSDPESDAKRRIVFT
LAGGAKQSPSHKHSGLPAGAPGHGPDSRKRGRRKRAAAAGTPSLSSSVSPKRRALPAVAG
LFSPSSGSPLNLNSMVSNINQPLEITAISSPESSLKSSPIPYQDDQPPVLKKEKPLGPSN
GAQYSPLTSDEEPGSEDEPASARIERKIATISLDSKSPPKSLENGGSVTGRKVTPVGEPV
NSSKWKATFSPISDLGLPKAADSPLQAGTALCQGSLFAFRSPLDDAAADPKLAAHSRKGF
SGPLATGGLSPSNPPNGFAFADLSLHSFNDGAGLALKGPEAAGLSAPLSFPGSRGKEGAA
ELGSFLNKRQLDGLGGPKGEAGKGKEAAEPGPPSSGAPDKQALAHGAKTGRSRDRDRETD
FKGGPNLFISAAAVPPGGLLSGQGLSTATSTSAGSAATSAQTHRPFLGTFAPAPQFALGP
MSLQANLGSSVLQSLFSSVPAAAGLVHVSSAATRLTNSHAMGSFSGVAGGAVGGVFNHAV
PSASSQSFGASFGSGAACHSAALSLAPLQAVATTPAASFQGPAPADPQPPPPPPAPHLGR
PPPGPPPPHVPGPPNAALPPAPALLASNSEPVLLQSLAPRPPNQAFLPPASAASLQPANA
SLSIKLASLPHKATRPSFTVHHQPLPGLALAPATPGIPPGSTTGPPAVWVSLGMPSPYAS
RLAGVKPR
NT seq
5067 nt
NT seq
+upstream
nt +downstream
nt
atggcggacgacgcccggcggcccaataggagtccggactccgcccactacggccatctg
gccccgcccaccgagactccggactgttccctctcatctaaccacgcccacgaggtgcgc
cctcgcagccccgtctcgtcggagagacccatcgtggggcggggcctgcagtgggcgggg
gcttcggacaaacaccatgatgctgctcacgaaatcatcgagacgatccggtgggtgtgc
gaagaaatcccagacctcaagctggccatggagaattacgtcttgatcgactacgataca
aaaagctttgagagcatgcagaggctctgcgacaagtacaaccgggccatcgacagcatc
caccagctgtggaaggggaccacgcagcccatgaagctgaacacgcggccgtccaacggg
ctcctgcggcacatcctgcagcaggtgtacaaccactccgtgaccgaccctgagaagctc
aacaactacgagcccttctcccccgaggtgtatggcgagacgtcctttgacctggtggca
cagatgatcgacgagatcaagatgaccgaggacgacctgttcgtggacctgggcagtggt
gtgggccaggtggtgctgcaggtcgcggcggccaccaactgcaggcatcattacggcgtg
gagaaagccgacatcccggccaagtacgcggagaccatggaccgagagttccggaagtgg
atgaaatggtacgggaaaaagcatgcagagtacacactggaaagaggcgactttctttca
gaagagtggagggagcgaatcgccaacacgagtgttatatttgtgaataactttgccttt
ggtcctgaggtggatcaccagctgaaggagcggtttgcaaacatgaaggaaggtggcaga
atcgtgtcctcgaagccctttgcccccttaaacttcagaatcaacagccggaacttgagc
gacattggcaccatcatgcgcgtggtggagctgtccccgctgaagggctccgtgtcgtgg
acggggaagccagtgtcctactatctgcacactatcgaccgtaccatacttgaaaactat
ttctctagtctgaaaaatcccaaactcagggactctggtgctgaggaagagaaagccggg
gcgaccaccgtcaaaaagccatccccctccaaggcccggaagaagaagctgaacaagaag
gggcgcaaaatggcgggccggaagcgggggcgccccaagaagctgagcgcgtcgcacccc
gagcgcaagccccgcaagggtcagacgccgctggagctgctgcacgcgcaggcggagccg
ccgcccgcctcgccctcaccccaggatgcctacaagtcacctcacagccccttctaccag
ctacctcccagcgtgcagcgccagccccccgaccagctgctgctggcccccaccccgccc
gcactgcagaagctgcttgagtccttcaaggtccagtatctgcagttcctggcctacacc
aagaccccacaatacaaagccaacctgcaacagctgctggaccaggagaaggagaagaac
gccaggctcctgggtgccgcgcagcagctgcttggccactgccaggcccagaaggatgag
atccggaggctctttcagcagaagctggacgagctgggcgtgaaggcgctgacctacaac
gacctgatccaagcacagaaggagatctcggcacacaaccggcagctgcgcgagcagacc
gagcagctggagaaggacacgcgggcactgcgggggcagagtctgcagctgctcaaggct
cggtgcgaggagctgaagctggactggtccacgctgtcgctggagacgctgctgaaggag
aagcaggcgctccgcagccagatctccgagaagcagcggcgctgcctggagctgcagatc
agcatcgtggagctggagaagaaccagcggcggcaggagctcttgcagctcaagtcatgc
gggccccccgacgagggcctgggcccccagcccggccggctgcccccggagttggacgcc
tccaagttctccctggcaccctttagtggcttgagccccgagctctccctcaacggccat
gcggcgggctacgagctctgtggggcactcagccggcccccctccaagcagaacaccccc
cagtacctggcgtcacccctagaccaggaggtggtgccctgcacccccagccacggcggc
cggcctcgcctcgacaagctgacaggcctggccctgcccgactacacccgcctgtcgccc
gccaagctggtactgcggcgacacctgagccaggagcccgcagctggtaccaaggcctca
agcgagctgcacccccgggccgagcacgccaaggagactgggagccccggcctggccaac
ggcatgaagctgagcccacaggacccgtggcctgcgtcccccggggccctgcccacagcc
ggggagaagggcagcgagaagggtgtgaaggagcgtggctccagcagcagcggggaggcc
atcaccagcctgcccgtcagcatcccgctgagcacggtgcagcccagcaagctgcccgtc
agcatccccctggcaagcgtggtgctccccagccgtgccgagaaggtgagtagaagcact
cccagcccagtgccccaggcccgggaggcctccacgctggacaaagggggtgcaggcagc
aaaggcctggcacaagtgcccgcaggcttctatgcgggctcagtggccatcagcggggcc
ctggcgggcagcccggcctccctggtgcccggggccgatccctcgaccttcgatgagtcc
tcaagctcagggagtctctttgccaccatgggctctcgcagctccaccccgcagcaccca
ccactgctggcgcagtcccggggcgcgggctccatctccccggcccaccagctctgcacc
agcccccggctcggtggcgccctccagggcccccttccggaccccggcaagggggagctg
ccagcggaggccagctgctcagaccccgagagtgacgccaagagacggatcgtcttcacc
ctggcgggcggcgccaagcagtcaccctcccacaagcacagtgggctgcctgcgggcgcc
ccgggccacgggcccgacagccgcaagcgaggccgcaggaagagggcagcagcagcgggc
acccccagcctgagctcgagcgtgtcccccaagcgccgggccctgccagccgttgccggc
ctcttctcgccgtcgtcgggctccccgctgaacctcaactccatggtcagcaacatcaac
cagcccctggagatcaccgccatctcgtcccccgagagctcgctcaagagctcccccatt
ccctaccaggatgaccagccccccgtgctcaagaaggagaagccgctgggcccgagcaac
ggcgcccagtactcgccgctcacctcggacgaagagccgggctctgaggacgagccggct
agtgccaggatcgagaggaagattgcaaccatctcattggacagcaagtcgcccccaaag
tccttggaaaatgggggcagcgtgaccggcaggaaggtcaccccggtgggcgagccggtc
aacagcagcaagtggaaggctaccttctcacccatctcggacctcggcctgcccaaggcc
gctgacagccccttgcaggcgggcacggcgctgtgccagggctccctgttcgccttccgg
tcccccctggacgacgcggccgctgaccccaagctggctgcgcactcaaggaaaggcttc
tctgggcccctggccacggggggcctcagccctagcaacccccccaacggcttcgccttc
gccgaccttagtttacacagcttcaacgatggtgctgggctggccctcaagggccccgag
gcagccggcctgagcgccccgctcagcttccccggctcccgcggcaaggagggcgccgcc
gaattgggctccttcctgaacaagagacagctggacggactggggggtcccaagggtgag
gctggcaagggcaaggaggccgctgagccgggcccaccctccagcggggcccccgacaag
caggccctcgcgcacggggccaagacgggccggagtcgcgaccgggaccgcgagacggac
ttcaagggcggccccaacctcttcatctctgccgctgccgttccccctgggggcctcctc
agcggccagggcctcagcacggcgacgtcgacctcggcgggcagcgcggccacctcggcg
cagacgcaccggcccttcctgggcaccttcgcgccggccccgcagttcgccctgggcccc
atgtccctgcaggccaacctgggctcgtctgtgctccagtccctgttcagctccgtgccc
gccgccgcgggcctggtgcacgtctcgtccgccgccaccagactgaccaactcgcatgcc
atgggcagcttctccggggtggccggcggggccgtcggaggtgtctttaaccacgcggtg
ccttccgcctcctcgcagtcgttcggagccagcttcggcagtggggctgcatgccacagc
gccgcgctgagcttagccccgctgcaggccgtggccaccacccccgccgcttcctttcag
ggcccggcccccgccgatccgcagccgcccccgcctccgccagctccgcacctgggccgg
cccccgccggggccgcccccgccccacgttcccggcccccctaacgctgccttgcctccc
gcccccgcgctgctggcgtctaactcggagcctgtgcttctgcagagcctcgcgccccgc
ccgcctaaccaagctttcttgccccccgcttctgccgcctcgctccagcctgctaacgcc
tctttgtccatcaagctcgcctccctcccgcacaaggccacccgcccctccttcacggtg
caccaccagcctctgcccgggctggccctggcgccggccacgcccgggatcccacccggc
agcaccacggggccacccgccgtgtgggtttccctgggcatgccgtctccgtatgcctcg
cgcctcgcgggggttaagccacgctaa
DBGET
integrated database retrieval system
