Sorex araneus (European shrew): 101544685
Help
Entry
101544685 CDS
T07854
Symbol
TOP2A
Name
(RefSeq) DNA topoisomerase 2-alpha
KO
K03164
DNA topoisomerase II [EC:
5.6.2.2
]
Organism
sara
Sorex araneus (European shrew)
Pathway
sara01524
Platinum drug resistance
Brite
KEGG Orthology (KO) [BR:
sara00001
]
09160 Human Diseases
09176 Drug resistance: antineoplastic
01524 Platinum drug resistance
101544685 (TOP2A)
09180 Brite Hierarchies
09182 Protein families: genetic information processing
03032 DNA replication proteins [BR:
sara03032
]
101544685 (TOP2A)
03036 Chromosome and associated proteins [BR:
sara03036
]
101544685 (TOP2A)
Enzymes [BR:
sara01000
]
5. Isomerases
5.6 Isomerases altering macromolecular conformation
5.6.2 Enzymes altering nucleic acid conformation
5.6.2.2 DNA topoisomerase (ATP-hydrolysing)
101544685 (TOP2A)
DNA replication proteins [BR:
sara03032
]
Eukaryotic type
DNA Topoisomerases
101544685 (TOP2A)
Chromosome and associated proteins [BR:
sara03036
]
Eukaryotic type
Chromosome condensation proteins
Other regulators of chromosome condensation
101544685 (TOP2A)
Centrosome formation proteins
Centriole proteins
101544685 (TOP2A)
BRITE hierarchy
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
DNA_topoisoIV
TOPRIM_C
DNA_gyraseB
DTHCT
HATPase_c
Toprim
Microp_apicomplexa_20
Motif
Other DBs
NCBI-GeneID:
101544685
NCBI-ProteinID:
XP_004608809
LinkDB
All DBs
Position
Unknown
AA seq
1538 aa
AA seq
DB search
MEVSPLQPVDENMQISKTKKNDDAKKRLSIERIYQKKTQLEHILLRPDTYIGSVELVTQQ
MWVYDEDVGINYREVTFVPGLYKIFDEILVNAADNKQRDPKMSCIRVTIDPENNLISIWN
NGKGIPVVEHKVEKMYVPALIFGQLLTSSNYDDDEKKVTGGRNGYGAKLCNIFSTKFTVE
TASREYKKMFKQTWMNNMGKAGDMELKPFNGEDYTCITFQPDLAKFKMQSLDKDIVALMV
RRAYDIAGSTKDVKVFLNGNKLPIKGFRSYVDMYLKDKVDETGNPLKIIHEQVNHRWEVC
LTMSEKGFQQISFVNSIATSKGGRHVDYIADQIVAKLVEVVKKKNKGGIAVKAHQVKNHM
WIFVNSLIENPTFDSQTKENMTLQVKSFGSTCQLSEKFIKAATGCGIVESILNWVKFKAQ
VQLNKKCSAVKHNRIKGIPKLDDANDAGGRNSTDCTLILTEGDSAKTLAVSGLGVVGRDK
YGVFPLRGKILNVREASHKQIMENAEINNIIKIVGLQYKKNYEDEDSLKSLRYGKIMIMT
DQDQDGSHIKGLLINFIHHNWPSLLRHRFLEEFITPIVKVSKNKQEISFYSLPEFEEWKS
SNPNHRKWKVKYYKGLGTSTSKEAKEYFSDMKRHRIQFKYSGPEDDAAISLAFSKKQTDD
RKEWLTHFMEDRRQRKLLGLPEDYLYGQTTTYLTYNDFINKELILFSNSDNERSIPSMVD
GLKPGQRKVLFTCFKRNDKREVKVAQLAGSVAEMSSYHHGEMSLMMTIINLAQNFVGSNN
LNLLQPIGQFGTRLHGGKDSASPRYIFTMLSPLARLLFPPKDDHTLRFLYDDNQRVEPEW
YIPIIPMVLINGAEGIGTGWSCKIPNFDVREVVNNIRRLMDGEEPLPMVPGYKNFKGTIE
ELAPNQYVISGEVAILNSTTIEITELPIRTWTQTYKEQVLEPMLNGTEKTPPLITDYREY
HTDTTVKFVVKMTEEKLAQAERAGLHKVFKLQSSLTCNSMVLFDHVGCLKKYDTVLDILR
DFYELRLKYYGLRKEWLLGMLGAESAKLNNQARFILEKIDGKIIIENKPKKELIKVLIQR
GYDSDPVKAWKEAQQKIPDEEENEESDNEKESEKSDSVTDSGPTFNYLLDMPLWYLTKEK
KDELCKLRKEKEEELEILKRKSPADLWREDLAAFVEELEAVEAKEKRDEQVGLPVKGGKA
KGKKPQMTEVLPSPSGKRVIPVVTVEMKAEAERKNKRKIKNENTEGSPQENGEAEGLKKR
LEKKLKKEKEPGAKTMKQTTLSFKPVKKGKKKNPWSDSESDMSSDESDFDVPPREIELRK
ASTKTKTMVDLDSDENFSDFDEKYQDEDDGDFVPSDDSLPTTKTSQKQTNKEQKPPKSAV
SVMDIDADDAKNDVPLSPSPPAADFTAKTETVEPISKKKVTVKKTAAKSQSSTTTAGTKK
RGAPKVTKKDSGLNSETSKKPDPTKTKIRRKRKPSSSDDSDSNFEERISKAAASKKSKGE
TDDFHQDLDSALAPRAKSGRAKKPIKYLEESDDDDDLF
NT seq
4617 nt
NT seq
+upstream
nt +downstream
nt
atggaggtgtcacccctgcagcccgtggatgaaaatatgcagatcagcaagaccaagaaa
aatgacgatgccaagaaaagattgtccattgaaagaatatatcaaaagaaaacacaactg
gagcacattttgctccggccagacacatacattggctccgtggagctagtgacccagcaa
atgtgggtttacgatgaagacgttggcatcaactacagggaagtcacttttgttcctggc
ttgtacaaaatctttgatgagattctagttaatgctgctgacaacaaacaaagggaccca
aaaatgtcttgcattagagtcacaattgacccagaaaacaatttaattagtatatggaat
aatggaaaaggtattcctgttgttgaacacaaagttgagaagatgtatgtcccagctctc
atctttggacaacttctaacctctagcaactatgacgatgatgagaagaaagtaacaggt
ggccgaaatggctatggagccaagttgtgtaatatattcagtaccaaatttaccgtggaa
acagccagtagagaatacaagaaaatgttcaaacagacatggatgaataacatggggaaa
gctggtgacatggaactcaagccctttaatggagaagattatacatgtattacctttcag
cctgatttggctaagtttaaaatgcaaagcctagacaaagatattgttgcacttatggtt
agaagagcatacgatattgctggatccactaaagatgtcaaagtcttcctcaatggaaat
aagctaccaataaaaggattccgtagctatgtggatatgtatttgaaggataaggtagat
gaaactggcaatccactgaaaattattcatgaacaagtaaatcaccggtgggaagtgtgc
ttaacaatgagtgaaaaaggctttcagcaaattagcttcgtcaatagcattgctacttcc
aagggtggcagacatgtagactatatcgctgatcagattgtggctaaacttgttgaagtt
gtcaagaagaaaaacaaaggtggtattgcagtaaaagcacatcaggtgaaaaatcacatg
tggatttttgtgaattccttaattgaaaatccaacctttgactctcagacaaaagaaaac
atgactttacaagtcaagagttttggatcaacatgccaactaagtgaaaaattcattaaa
gctgcaactggctgtggtatcgtagaaagcatattaaactgggtgaagtttaaagcccag
gtccaattaaacaagaagtgttcagctgtaaaacataacagaatcaaaggaattcctaaa
ctcgatgatgccaatgatgcagggggtcgaaactccactgactgtacactgatcctgact
gaaggagactcggccaaaactttggctgtttcagggcttggtgtggttggaagagacaaa
tatggggttttcccacttagaggaaaaatactcaatgttcgagaagcttctcataagcag
atcatggaaaatgctgaaattaacaatatcatcaagattgtgggtcttcagtacaagaaa
aactatgaagatgaagattcattaaagtctcttcgttatggaaagataatgatcatgaca
gatcaggatcaagacggttcccacattaaaggcttattgattaattttatccatcacaat
tggccgtctcttctacgtcatcgttttctggaagaatttatcacacccattgtaaaggtg
tctaaaaacaagcaagaaatatcattttatagccttcctgaatttgaagaatggaagagt
tctaatccaaatcatagaaaatggaaagtcaagtattacaaaggtttgggcaccagcaca
tcaaaagaagctaaagaatatttctcagatatgaaaagacatcgcatccaattcaaatat
tctggacctgaagatgatgctgccatcagcctggccttcagcaaaaaacaaacagatgat
cggaaggaatggttaactcatttcatggaagacagaaggcagcgaaagttacttggtctt
cctgaggattacttgtacggacaaactaccacgtatctgacatataatgacttcataaac
aaggagcttattcttttttccaattctgataatgaaagatctattccatctatggtagat
ggtttgaaaccagggcagagaaaggtattgtttacttgtttcaaacggaatgacaagcga
gaggtgaaagttgcccagcttgctgggtcagtggctgagatgtcctcctatcaccatggt
gagatgtcactgatgatgaccattatcaacttggcccaaaattttgtggggagcaataat
ttaaacctcttgcaacccattggtcagtttggtaccaggctacatggtggcaaagattct
gctagtcctcgatacatcttcacaatgctcagccctttggctaggttgttattcccacca
aaggatgatcataccttaagattcttatatgatgacaaccaacgtgttgagcctgaatgg
tacattcctattatccccatggtgctgataaacggtgctgaaggaattggtacagggtgg
tcctgcaaaatccctaattttgatgttcgtgaagttgtaaataacatcaggcgtttgatg
gatggagaagaacctttaccaatggttccaggttacaagaacttcaagggaacaatcgaa
gagctggctccaaatcaatacgtgattagtggtgaagtggcgattcttaattccacaacc
attgaaatcacagagcttcccatcagaacatggacccagacatataaggaacaagttctt
gagcccatgttgaatggaaccgagaagactcccccactcatcacagactatcgagaatac
cacacagataccaccgtgaagtttgttgtgaagatgacagaagaaaaactggcacaagca
gaaagagctggacttcacaaagtcttcaaactccaatctagtctcacatgcaactctatg
gtgctttttgaccacgtaggctgcttaaagaaatatgataccgtattagatattctaaga
gacttctatgaactcaggcttaaatattatggactgagaaaagaatggcttctgggaatg
cttggtgctgaatctgctaaactgaataatcaggctcgctttatcttagagaaaatcgat
ggcaaaataatcattgaaaataaacctaagaaagaattaattaaggttttgatccagagg
ggatatgactcagatcctgtcaaggcttggaaagaagcccagcaaaagattccagatgaa
gaagaaaatgaagagagtgataatgaaaaggaatctgaaaaaagtgactctgtgacagat
tctggaccaaccttcaattaccttcttgatatgcctctttggtatctaactaaggagaag
aaggatgaactatgcaaactgagaaaggaaaaagaggaagaattagaaatattaaagagg
aagagcccagcagacttatggagagaagacttggctgcttttgttgaagaactggaggct
gttgaagccaaggaaaaaagggatgaacaagtaggattacctgtgaaaggtggaaaagca
aaggggaaaaaaccccaaatgaccgaagtcttgccttctccaagtggaaaaagagtcatc
cctgtagtgactgtagagatgaaagcagaggcagaaaggaaaaataaaaggaaaattaag
aatgaaaacactgaaggaagcccacaggagaatggtgaagcagaaggccttaaaaaaaga
ttagaaaagaaactgaaaaaagaaaaagaaccaggtgccaagacaatgaaacaaactaca
ttgtcttttaagccagtcaaaaaagggaagaagaaaaacccctggtctgattcagaatca
gatatgagcagtgatgaaagtgattttgatgtccctccacgagaaatagagctacggaaa
gcatcaacaaaaactaaaaccatggtagatttggattcagatgaaaatttctctgatttt
gatgaaaaatatcaagatgaagatgatggagattttgttccatcagatgacagtctacct
acaaccaaaacttcccaaaaacaaactaacaaagaacagaaaccaccaaaaagtgccgta
tcggtaatggacattgatgctgatgatgccaagaatgatgtaccactttccccaagcccc
cctgctgccgattttacagctaaaacggaaactgtagagcctatttctaaaaagaaggtg
acggtgaagaaaacagcagcaaaaagtcaatcttccaccaccactgcaggcaccaaaaaa
cggggtgcaccaaaagtaaccaaaaaggattctggcttgaattctgaaacctctaaaaag
cctgaccccactaaaacgaagattcgtcgcaaaaggaaaccttcttcttctgatgattct
gactctaattttgaggagagaatttctaaggcagctgcaagtaagaaatccaagggggag
accgatgacttccatcaggacttagactcagctctcgccccacgggcaaaatctggacgg
gcaaagaagcctataaagtaccttgaagagtcagatgatgacgatgatctgttttaa
DBGET
integrated database retrieval system
