Sorex araneus (European shrew): 101545951
Help
Entry
101545951 CDS
T07854
Symbol
LRP6
Name
(RefSeq) low-density lipoprotein receptor-related protein 6
KO
K03068
low density lipoprotein receptor-related protein 5/6
Organism
sara
Sorex araneus (European shrew)
Pathway
sara04150
mTOR signaling pathway
sara04310
Wnt signaling pathway
sara04928
Parathyroid hormone synthesis, secretion and action
sara05010
Alzheimer disease
sara05022
Pathways of neurodegeneration - multiple diseases
sara05200
Pathways in cancer
sara05224
Breast cancer
sara05225
Hepatocellular carcinoma
sara05226
Gastric cancer
Brite
KEGG Orthology (KO) [BR:
sara00001
]
09130 Environmental Information Processing
09132 Signal transduction
04310 Wnt signaling pathway
101545951 (LRP6)
04150 mTOR signaling pathway
101545951 (LRP6)
09150 Organismal Systems
09152 Endocrine system
04928 Parathyroid hormone synthesis, secretion and action
101545951 (LRP6)
09160 Human Diseases
09161 Cancer: overview
05200 Pathways in cancer
101545951 (LRP6)
09162 Cancer: specific types
05225 Hepatocellular carcinoma
101545951 (LRP6)
05226 Gastric cancer
101545951 (LRP6)
05224 Breast cancer
101545951 (LRP6)
09164 Neurodegenerative disease
05010 Alzheimer disease
101545951 (LRP6)
05022 Pathways of neurodegeneration - multiple diseases
101545951 (LRP6)
09180 Brite Hierarchies
09182 Protein families: genetic information processing
04131 Membrane trafficking [BR:
sara04131
]
101545951 (LRP6)
Membrane trafficking [BR:
sara04131
]
Endocytosis
Clathrin-mediated endocytosis
Low-density lipoprotein receptor (LDLR) family proteins
101545951 (LRP6)
BRITE hierarchy
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
Ldl_recept_b
FXa_inhibition
Ldl_recept_a
Vgb_lyase
SGL
DUF5050
EGF_LRP2
cEGF
Motif
Other DBs
NCBI-GeneID:
101545951
NCBI-ProteinID:
XP_012788843
LinkDB
All DBs
Position
Unknown
AA seq
1581 aa
AA seq
DB search
MGHEKAPRDRAAPLLLYANRRDLRLVDATNGRENATIVVGGLEDAAAVDFVFGHGLIYWS
DVSEEAIKRAEFNRTESVQNVVVSGLLSPDGLACDWLGEKLYWTDSETNRIEVSNLDGSL
RKVLFWQELDQPRAIALDPSSGFMYWTDWGEVPKIERAGMDGSSRYIIINTEIYWPNGLT
LDYEERKLYWADAKLNFIHKSNLDGTNRQAVVKGSLPHPFALTLFEDTLYWTDWNTHSIL
ACNKYTGEGLREIHSNIFSPMDIHAFSQQRQPNATNPCGSDNGGCSHLCLMSPVKPFYQC
ACPTGVRLLENGKTCKDGATELLLLARRTDLRRISLDTPDFTDIVLQLEDIRHAIAIDYD
PVEGYIYWTDDEVRAIRRSFIDGSGSQFVVTAQIAHPDGIAVDWVARNLYWTDTGTDRIE
VTRLNGTMRKILISEDLEEPRAIVLDPMIGYMYWTDWGEIPKIERAALDGSDRVVLVNTS
LGWPNGLALDYDEGKIYWGDAKTDKIEELSLDEDFQCLYLYPSGDLHKRSAEREIIIDQL
PDLMGLKATNVHRIFGSNPCAEENGGCSHLCLYRPQGLRCACPIGFELISDMKTCIVPEA
FLLFSRRADIRRISLETNNNNVAIPLTGVKEASALDFDVTDNRIYWTDISLKTISRAFMN
GSALEHVVEFGLDYPEGMAVDWLGKNLYWADTGTNRIEVSKLDGQHRQVLVWKDLDSPRA
LALDPAEGFMYWTEWGGKPKIDRAAMDGSERTTLVPNVGRANGLTIDYAKRRLYWTDLDT
NLIESSNMLGLNREVIADDLPHPFGLTQYQDYIYWTDWSRRSIERANKTSGQNRTIIQGH
LDYVMDILVFHSSRQAGWNECASSNGHCSHLCLAVPVGGFVCGCPAHYSLNADNRTCSAP
TTFLLFSQKSAINRMVIDEQQSPDIILPIHSLRNVRAIDYDPLDKQLYWIDSRQNVIRKA
QEDGGQGFTVVVSSVPNQNLEIQPYDLSIDIYSRYIYWTCEATNVINVTRLDGRSIGVVL
KGDQDRPRAIVVNPEKGYMYFTNLQERSPKIERAALDGTEREVLFFSGLSKPIALALDSR
LGKLFWADSDLRRIESSDLSGANRIVLEDSNILQPVGLTVFENWLYWIDKQQQMIEKIDM
TGRESRTKVQARIAQLSDIHAVKELNLQEYRQHPCAQDNGGCSHICLVKGDGTTRCSCPM
HLVLLQDELSCGEPPTCSPQQFTCFTGEIDCIPVAWRCDGFTECEDHSDELNCPVCSESQ
FQCASGQCVDGALRCNGDANCQDKSDEKNCEVLCLIDQFRCANGQCIGKHKKCDHNVDCS
DKSDELDCYPTEEPAPQATNTVGSVIGVIITILVSGTIYFICQRMLCPRMKGDGETMTND
YVVHGPASVPLGYVPHPSSLSGSLPGMSRGKSMISSLSIMGGSSGPPYDRAHVTGASSSS
SSSTKGTYFPAILNPPPSPATERSHYTMEFGYSSNSPSTHRSYSYRPYSYRHFAPPTTPC
STDVCDSDYAPSRRMTSVATAKGYTSDLNYDSEPVPPPPTPRSQYLSAEENYESCPPSPY
TERSYSHHLYPPPPSPCTDSS
NT seq
4746 nt
NT seq
+upstream
nt +downstream
nt
atggggcatgagaaggcacctagagacagagcggcccctttgttgctttatgcaaacaga
cgggacttgcgattggtcgatgctacaaatggcagagagaatgccaccattgtagtcgga
ggcctggaggatgctgcagcggtggactttgtgtttggccatggcttgatatactggagt
gatgtcagcgaagaagccattaaacgagcagagtttaaccggactgagagtgtgcagaat
gttgtggtttctggattactgtcccctgatggactggcatgtgattggcttggggaaaaa
ttatattggacagattcagaaactaaccggattgaagtttctaatttagatggatcttta
cgaaaagttttattttggcaagagttggatcaacccagagctattgctttagatccttca
agtgggttcatgtactggacagactggggagaagtgccaaagatagaacgtgctggaatg
gatggttcaagtcgctacattataataaacactgaaatttactggccaaatggattgact
ttggattatgaggaacggaaactttattgggcagatgcaaaacttaatttcatccacaaa
tcaaatttggatggaacaaatcggcaggcagttgttaaaggttcccttccacatccgttt
gctttgacgttatttgaggacacattgtactggactgactggaatacacactccattttg
gcttgcaacaagtacactggcgagggtctgcgtgaaatccattctaacatcttctctccc
atggatatacatgctttcagccagcagaggcagccaaatgctacaaatccatgtggaagt
gataatggtggttgttcccacttgtgtttgatgtctccagtcaagcctttctatcagtgt
gcttgcccaacgggggtcagacttctagagaatggaaaaacctgcaaagatggggccact
gaattactgcttttagcccgaaggacagacttgagacgcatttccttggatacaccagat
ttcacagacattgttctacagttagaagacattcgtcatgccattgccatagattatgat
cccgtagaaggctatatctactggactgacgatgaagtgagggcaatacgccgttcattc
atagatggatctggaagtcagtttgtggtcactgctcagattgctcatcctgacggaatt
gctgttgattgggtcgcccgaaatctttattggacagatactggcactgatcgaatagaa
gtgacaagactcaatgggaccatgaggaagatcttgatttcagaggacttagaggaaccc
cgagccattgtgttagatcctatgattgggtacatgtattggactgactggggagaaatc
ccgaaaatcgagcgagcagctctggacggttctgaccgagtagtgttggtgaacacttct
cttggttggccaaatggtttagccttggattatgatgaaggcaaaatatactggggagat
gccaaaacagacaaaattgaggaattgtcattagatgaagattttcagtgtctgtacctt
tatcccagtggtgatttacacaaacgaagtgcagagagggaaatcatcatagatcagctt
cctgacctcatgggcctcaaagccacaaatgttcatagaatctttggttctaatccctgt
gctgaggaaaatggggggtgtagccatctttgcctctatagaccacagggccttcgctgt
gcttgccccattggctttgagctcatcagcgacatgaagacctgcattgtcccagaggct
ttccttttgttttcacggagagcagatatcagacgaatttctttggaaacaaacaacaat
aatgtcgccattccgctcactggcgtcaaagaagcttctgctttggattttgatgtgaca
gacaaccgaatttactggactgacatatctctcaagaccatcagcagagcctttatgaat
ggcagtgcactggagcatgtggtagaatttggcttagattatccagaaggcatggcagtg
gattggcttggcaagaacttgtactgggcagacacaggaacgaatcgaattgaagtgtca
aagttggatgggcagcacagacaggttttggtgtggaaagacctcgatagtcccagagct
cttgcattggatcctgctgaagggtttatgtattggactgaatggggtggaaaacctaag
atagacagagctgctatggacggaagtgaacgaaccacactagttccaaacgtggggcga
gcaaatggcctaactattgattatgctaaaaggagactttattggacagaccttgatacc
aacttaatagaatcttcaaatatgcttggactcaaccgtgaagttatagcagatgacttg
cctcatccttttggcttaactcagtaccaagattacatctactggacggattggagccga
cgcagcattgagcgtgccaacaaaaccagcggccaaaaccgcaccatcattcagggccat
ttggattatgtgatggacatcctcgtctttcactcctctcgacaggcaggatggaatgaa
tgtgcttccagcaatgggcactgctcccacctctgcttggctgtgccagtaggaggtttt
gtttgtggatgtcctgcccactactctcttaatgctgacaacaggacttgtagtgctcca
accaccttcttactcttcagtcagaaaagtgccatcaaccgcatggtgattgatgaacag
caaagccctgacatcatccttcctatccacagtcttcggaatgttcgggccattgactat
gacccactggacaagcagctctattggattgactcgcggcaaaatgtgattcgaaaagca
caagaagatggtggccagggctttaccgtggttgtgagctcagttccaaatcagaaccta
gaaatccagccctatgatctcagcattgatatttatagccgctacatttactggacttgt
gaggctacgaatgtgattaatgtaacaagattagatgggagatcgattggagtggtgctc
aaaggggaccaagacagacctcgggccattgtggtgaatcctgagaaagggtatatgtat
tttactaatcttcaggaaaggtcacccaaaattgaacgagctgctttggatggaacagaa
cgtgaggtcctctttttcagtggtctaagtaaaccaattgctttagcccttgatagcaga
ttgggcaagctcttttgggctgattcggaccttcgacgaattgaaagcagtgatctttca
ggtgccaaccgtatagtattagaggactccaatatcttgcagcctgtggggctgactgtg
tttgaaaattggctgtactggattgataaacagcagcaaatgatcgaaaaaattgacatg
acaggccgggagagtagaaccaaagtccaggctcgaattgctcagctgagtgacatccac
gccgtgaaggagctgaacctgcaggagtaccgacaacatccttgtgctcaggataatggt
ggctgctcacatatctgtcttgtgaaaggagatggtacgaccaggtgctcttgccccatg
catttagttctgctgcaagatgagttatcatgtggagaacccccaacgtgttctccacag
cagttcacttgtttcacgggggaaatcgactgtattcctgtggcctggcggtgtgacggg
tttactgaatgtgaggaccacagcgatgagctcaattgtcccgtgtgctcagagtcccag
ttccagtgcgccagcgggcagtgtgttgacggtgcccttcgatgcaatggagatgccaac
tgccaagataaatcagatgagaagaactgtgaagtactttgtttaattgatcagttccgc
tgtgccaatggtcagtgcattggaaagcacaagaaatgtgatcataatgtggattgcagt
gacaaatcagatgagctggattgttatccaacggaggagccagcaccacaggccaccaat
acagttggttcagttattggagtgattatcaccattttggtgtctggaaccatatacttt
atctgccaaaggatgttgtgtccacgtatgaaaggagatggggaaaccatgactaatgac
tatgtagttcacggaccagcttctgtgcccctgggttatgtgcctcacccaagttctttg
tcaggctctctgccaggaatgtctagaggcaaatcgatgatcagctctctcagtatcatg
ggcgggagcagtgggcccccttacgaccgtgctcatgtcacaggcgcatcttcaagtagt
tcatcaagcaccaaaggcacttacttcccagctattttgaaccctcctccatccccagcc
acagaacgatcccattacactatggaatttggttattcttcgaacagtccatctactcat
aggtcctacagctataggccatacagttaccggcactttgcacctcccacgaccccctgc
agtacggacgtctgtgacagtgactatgcgcccagcaggagaatgacttcagtggcaacc
gccaaggggtacaccagtgacttgaactatgactcagagcctgtgcccccgcctcccaca
ccccgcagccagtacttgtcagcagaagagaactatgaaagctgcccgccttccccgtac
acagagaggagctactctcatcacctctacccgccgccgccctcgccctgcaccgactcc
tcctga
DBGET
integrated database retrieval system
